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  1. Article ; Online: Advances in Feline Viruses and Viral Diseases.

    Beatty, Julia A / Hartmann, Katrin

    Viruses

    2021  Volume 13, Issue 5

    Abstract: Viral diseases play a very important role in feline medicine, and research on feline viruses and viral diseases is a well-established field that helps to safeguard the health of domestic cats and non-domestic felids, many of which are endangered [ ... ]. ...

    Abstract Viral diseases play a very important role in feline medicine, and research on feline viruses and viral diseases is a well-established field that helps to safeguard the health of domestic cats and non-domestic felids, many of which are endangered [...].
    MeSH term(s) Animals ; Animals, Domestic ; Cat Diseases/epidemiology ; Cat Diseases/virology ; Cats ; Disease Susceptibility ; Humans ; Public Health
    Language English
    Publishing date 2021-05-17
    Publishing country Switzerland
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v13050923
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Advances in Feline Viruses and Viral Diseases

    Beatty, Julia A / Hartmann, Katrin

    Viruses. 2021 May 17, v. 13, no. 5

    2021  

    Abstract: Viral diseases play a very important role in feline medicine, and research on feline viruses and viral diseases is a well-established field that helps to safeguard the health of domestic cats and non-domestic felids, many of which are endangered [ ... ] ...

    Abstract Viral diseases play a very important role in feline medicine, and research on feline viruses and viral diseases is a well-established field that helps to safeguard the health of domestic cats and non-domestic felids, many of which are endangered [...]
    Keywords Felidae ; cats ; medicine
    Language English
    Dates of publication 2021-0517
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 2516098-9
    ISSN 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v13050923
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Successful management of feline pemphigus foliaceus with pentoxifylline and topical hydrocortisone aceponate.

    Hobi, Stefan / Beatty, Julia A / Sandy, Jeanine R / Barrs, Vanessa R

    Veterinary medicine and science

    2022  Volume 8, Issue 3, Page(s) 937–944

    Abstract: The treatment regimen for feline pemphigus foliaceus (PF), an autoimmune disease caused by auto-antibodies against proteins of the desmosome junction, usually includes high doses of oral or parenteral immunosuppressive drugs, typically glucocorticoids. ... ...

    Abstract The treatment regimen for feline pemphigus foliaceus (PF), an autoimmune disease caused by auto-antibodies against proteins of the desmosome junction, usually includes high doses of oral or parenteral immunosuppressive drugs, typically glucocorticoids. This case adds to a growing body of evidence that topical hydrocortisone aceponate is effective for the treatment of feline PF, and demonstrates the practical use of a non-invasive diagnostic method for histopathology when owners refuse a biopsy to support a clinical diagnosis of PF. Finally, this case highlights an international trend of owner-initiated treatment of feline infectious peritonitis (FIP) using unlicensed, unregistered drugs.
    MeSH term(s) Animals ; Cat Diseases/drug therapy ; Cats ; Glucocorticoids/therapeutic use ; Hydrocortisone/analogs & derivatives ; Immunosuppressive Agents ; Pemphigus/diagnosis ; Pemphigus/drug therapy ; Pemphigus/veterinary ; Pentoxifylline/therapeutic use
    Chemical Substances Glucocorticoids ; Immunosuppressive Agents ; hydrocortisone aceponate (2340UP1L2G) ; Pentoxifylline (SD6QCT3TSU) ; Hydrocortisone (WI4X0X7BPJ)
    Language English
    Publishing date 2022-02-25
    Publishing country England
    Document type Case Reports ; Research Support, Non-U.S. Gov't
    ZDB-ID 2819409-3
    ISSN 2053-1095 ; 2053-1095
    ISSN (online) 2053-1095
    ISSN 2053-1095
    DOI 10.1002/vms3.768
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Babesia gibsoni

    Almendros, Angel / Choi, Y R / Bęczkowski, Paweł M / Baiker, Kerstin / Barrs, Vanessa R / Beatty, Julia A

    Animals : an open access journal from MDPI

    2023  Volume 13, Issue 13

    Abstract: Tick-borne ... ...

    Abstract Tick-borne haemoparasite
    Language English
    Publishing date 2023-06-27
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani13132128
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Epidemiology of Pathogenic Retroviruses and Domestic Cat Hepadnavirus in Community and Client-Owned Cats in Hong Kong.

    Beatty, Julia A / Choi, Yan Ru / Nekouei, Omid / Woodhouse, Fiona M / Gray, Jane J / Hofmann-Lehmann, Regina / Barrs, Vanessa R

    Viruses

    2024  Volume 16, Issue 2

    Abstract: Understanding the local epidemiology of feline leukaemia virus (FeLV) and feline immunodeficiency virus (FIV) in Hong Kong will inform retrovirus prevention strategies. Domestic cat hepadnavirus (DCH), a novel hepatitis-B-like virus, is commonly detected ...

    Abstract Understanding the local epidemiology of feline leukaemia virus (FeLV) and feline immunodeficiency virus (FIV) in Hong Kong will inform retrovirus prevention strategies. Domestic cat hepadnavirus (DCH), a novel hepatitis-B-like virus, is commonly detected among client-owned cats in Hong Kong, but community cats have not been studied. The aims of this study were to investigate the frequency and potential risk factors for (i) FeLV and FIV among community and client-owned cats and (ii) perform molecular detection of DCH among community cats in Hong Kong. Blood samples from 713 cats were obtained from client-owned (n = 415, residual diagnostic) and community cats (n = 298, at trap-neuter-return). Point-of-care (POC) testing for FeLV antigen and feline immunodeficiency virus (FIV) anti-p15 and p24 antibodies was performed. FeLV-positive samples were progressed to p27 sandwich enzyme-linked immunosorbent assay. Whole blood DNA was tested with qPCRs for FeLV U3 and gag, and nested PCRs where additional information was required. DCH qPCR was performed on a subset of community cats (n = 193). A single, regressive, FeLV infection was detected in a client-owned cat (1/415 FeLV U3 qPCR positive, 0.2%, 95% CI 0.0-1.3%). Five/415 client-owned cats tested presumably false FeLV-antigen positive (qPCR negative). No markers of FeLV infection were detected in community cats (0/298; 0%). FIV seroprevalence was much higher in community cats (46/298, 15.4%) than in client-owned cats (13/415, 3.1%) (
    MeSH term(s) Humans ; Animals ; Cats ; Feline Acquired Immunodeficiency Syndrome ; Retroviridae/genetics ; Hepadnaviridae/genetics ; Seroepidemiologic Studies ; Hong Kong/epidemiology ; Immunodeficiency Virus, Feline/genetics ; Leukemia, Feline ; Leukemia Virus, Feline/genetics ; Antibodies, Viral ; DNA ; Cat Diseases/diagnosis ; Cat Diseases/epidemiology
    Chemical Substances Antibodies, Viral ; DNA (9007-49-2)
    Language English
    Publishing date 2024-01-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v16020167
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Babesia gibsoni Infection in a Cat with Immune-Mediated Haemolytic Anaemia and Thrombocytopenia

    Almendros, Angel / Choi, Y. R. / Bęczkowski, Paweł M. / Baiker, Kerstin / Barrs, Vanessa R. / Beatty, Julia A.

    Animals. 2023 June 27, v. 13, no. 13

    2023  

    Abstract: Tick-borne haemoparasite Babesia gibsoni has been detected rarely in cats, in surveys of apparently healthy animals. In stored blood from a 6-year-old male-neutered domestic shorthair cat in Hong Kong, B. gibsoni DNA was detected retrospectively using ... ...

    Abstract Tick-borne haemoparasite Babesia gibsoni has been detected rarely in cats, in surveys of apparently healthy animals. In stored blood from a 6-year-old male-neutered domestic shorthair cat in Hong Kong, B. gibsoni DNA was detected retrospectively using PCR for Babesia spp. 18S rRNA and mitochondrial cytochrome B genes, followed by sequencing and basic local alignment search tool (BLAST) analysis. The cat presented with severe haemolytic anaemia and thrombocytopenia. The cat responded to supportive care and glucocorticoids and was clinically normal despite persistent subclinical thrombocytopenia until six months after presentation, when it succumbed to a fatal haemorrhagic episode. Necropsy revealed severe intestinal and pulmonary haemorrhage and hypocellular bone marrow with megakaryocytosis but no other causes of immune-mediated thrombocytopenia (IMTP) or immune-mediated haemolytic anaemia (IMHA). Blood stored on days 158 and 180 tested PCR negative for Babesia spp. This report demonstrates that geographic range of B. gibsoni detection in cats includes Hong Kong. The exclusion of other causes suggests that B. gibsoni might have potentially played a role in triggering immune-mediated disease in this case.
    Keywords Babesia gibsoni ; DNA ; blood ; bone marrow ; cytochrome b ; geographical distribution ; glucocorticoids ; hemolytic anemia ; hemoparasites ; hemorrhage ; intestines ; mitochondria ; necropsy ; thrombocytopenia ; China
    Language English
    Dates of publication 2023-0627
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani13132128
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Nasal Lymphoma with Low Mitotic Index in Three Cats Treated with Chlorambucil and Prednisolone

    Ng, Karen W. L. / Beatty, Julia A. / Tse, May P. Y. / Giuliano, Antonio

    Veterinary sciences. 2022 Sept. 01, v. 9, no. 9

    2022  

    Abstract: Lymphoma is the most common tumor of the nasal cavity in cats. Commonly used treatment modalities are radiotherapy and chemotherapy, or both. Typical chemotherapy protocols used in cats with nasal lymphoma are COP (cyclophosphamide, vincristine ... ...

    Abstract Lymphoma is the most common tumor of the nasal cavity in cats. Commonly used treatment modalities are radiotherapy and chemotherapy, or both. Typical chemotherapy protocols used in cats with nasal lymphoma are COP (cyclophosphamide, vincristine prednisolone) and CHOP (cyclophosphamide, doxorubicin, vincristine and prednisolone). Thus far, the use of single-agent chlorambucil in nasal lymphoma has been evaluated in a single case report. We report a case series of three cats with B cell nasal lymphoma, two cats with intermediate cell, and one large cell, all with a low mitotic index (MI) of less than 5 mitotic figures per ×400 field, treated with chlorambucil and prednisolone. Two of the cases achieved a long disease-free interval, while the one with the highest MI did not. Protocols using chlorambucil and prednisolone may have potential as a first-line therapy for feline nasal lymphoma cases with a very low mitotic index.
    Keywords B-lymphocytes ; case studies ; cats ; cyclophosphamide ; doxorubicin ; drug therapy ; lymphoma ; mitosis ; nasal cavity ; prednisolone ; radiotherapy ; vincristine
    Language English
    Dates of publication 2022-0901
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2768971-2
    ISSN 2306-7381
    ISSN 2306-7381
    DOI 10.3390/vetsci9090472
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Brachycephalic obstructive airway syndrome: much more than a surgical problem

    Mitze, Stefanie / Barrs, Vanessa R. / Beatty, Julia A. / Hobi, Stefan / Bęczkowski, Paweł M.

    Veterinary Quarterly. 2022 Dec. 2, v. 42, no. 1 p.213-223

    2022  

    Abstract: Brachycephalic obstructive airway syndrome (BOAS) is a chronic, lifelong, debilitating, primarily obstructive airway disease which adversely affects the quality of life of many popular dog breeds. Respiratory restriction in bulldog breeds, pugs and ... ...

    Abstract Brachycephalic obstructive airway syndrome (BOAS) is a chronic, lifelong, debilitating, primarily obstructive airway disease which adversely affects the quality of life of many popular dog breeds. Respiratory restriction in bulldog breeds, pugs and Boston terriers frequently co-exist with pathologies of the gastrointestinal tract. In addition, many brachycephalic dogs that appear clinically normal are, in fact suffering from chronic hypoxia and its systemic consequences. Concurrent gastroesophageal reflux-associated conditions, sleep disorders and systemic hypertension further impact the welfare of affected dogs. Acceptance of BOAS and associated clinical signs as being ‘normal for the breed’ is common amongst owners. While surgical correction of the upper airway is the mainstay of treatment, the provision of subsequent, frequently lifelong medical management is equally important for the maintenance of an acceptable quality of life, at least for some affected patients. Here we review the current knowledge concerning brachycephaly, combine it with shared clinical experience in the management of this debilitating condition, and discuss ethical considerations and the responsibility of veterinarians to contribute public education and to support appropriate breed standards for animals under our care.
    Keywords digestive tract ; dogs ; education ; ethics ; hypertension ; hypoxia ; quality of life ; sleep ; Canine ; bulldog ; brachycephaly ; airway obstruction ; surgery ; ethical ; welfare
    Language English
    Dates of publication 2022-1202
    Size p. 213-223.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ZDB-ID 754161-2
    ISSN 1875-5941 ; 0165-2176
    ISSN (online) 1875-5941
    ISSN 0165-2176
    DOI 10.1080/01652176.2022.2145621
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  9. Article ; Online: A shift towards early-age desexing of cats under veterinary care in Australia.

    Mazeau, Loic / Wylie, Claire / Boland, Lara / Beatty, Julia A

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 811

    Abstract: The global problem of unowned domestic cats, driven by their phenomenal reproductive success, carries significant economic, animal welfare and biodiversity costs. Desexing owned cats prior to puberty prevents unwanted litters that contribute to unowned ... ...

    Abstract The global problem of unowned domestic cats, driven by their phenomenal reproductive success, carries significant economic, animal welfare and biodiversity costs. Desexing owned cats prior to puberty prevents unwanted litters that contribute to unowned cat populations. The prevalence and predictors of desexing, and the age at which surgery was carried out were investigated using anonymized electronic patient records in the VetCompass Australia database of cats presented to veterinary practices. Of 52,941 cats born between 2010 and 2017, 83.6% were desexed. Among 7463 desexed females, 21.5% had been desexed by 4 months of age, 59.8% by 6 months and 85.4% by 1 year. Sex, breed, location and socioeconomic indices significantly influenced desexing status and age at surgery. Cats born between 2010 and 2017 had greater odds of being desexed than cats born between 1995and 2009 at each age cut-off (≤ 4 months [OR 1.76, CI
    MeSH term(s) Animal Welfare ; Animals ; Australia ; Castration ; Cats ; Female ; Male ; Sexual Maturation
    Language English
    Publishing date 2021-01-18
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-020-79513-6
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  10. Article ; Online: Nasal Lymphoma with Low Mitotic Index in Three Cats Treated with Chlorambucil and Prednisolone.

    Ng, Karen W L / Beatty, Julia A / Tse, May P Y / Giuliano, Antonio

    Veterinary sciences

    2022  Volume 9, Issue 9

    Abstract: Lymphoma is the most common tumor of the nasal cavity in cats. Commonly used treatment modalities are radiotherapy and chemotherapy, or both. Typical chemotherapy protocols used in cats with nasal lymphoma are COP (cyclophosphamide, vincristine ... ...

    Abstract Lymphoma is the most common tumor of the nasal cavity in cats. Commonly used treatment modalities are radiotherapy and chemotherapy, or both. Typical chemotherapy protocols used in cats with nasal lymphoma are COP (cyclophosphamide, vincristine prednisolone) and CHOP (cyclophosphamide, doxorubicin, vincristine and prednisolone). Thus far, the use of single-agent chlorambucil in nasal lymphoma has been evaluated in a single case report. We report a case series of three cats with B cell nasal lymphoma, two cats with intermediate cell, and one large cell, all with a low mitotic index (MI) of less than 5 mitotic figures per ×400 field, treated with chlorambucil and prednisolone. Two of the cases achieved a long disease-free interval, while the one with the highest MI did not. Protocols using chlorambucil and prednisolone may have potential as a first-line therapy for feline nasal lymphoma cases with a very low mitotic index.
    Language English
    Publishing date 2022-09-01
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2768971-2
    ISSN 2306-7381 ; 2306-7381
    ISSN (online) 2306-7381
    ISSN 2306-7381
    DOI 10.3390/vetsci9090472
    Database MEDical Literature Analysis and Retrieval System OnLINE

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