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  1. Article ; Online: When should I give corticosteroids to my patient with

    Gupta, Simran / Bebell, Lisa M

    Cleveland Clinic journal of medicine

    2024  Volume 91, Issue 4, Page(s) 217–219

    MeSH term(s) Humans ; Pneumonia, Pneumocystis/complications ; Pneumonia, Pneumocystis/drug therapy ; Adrenal Cortex Hormones/therapeutic use
    Chemical Substances Adrenal Cortex Hormones
    Language English
    Publishing date 2024-04-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639116-3
    ISSN 1939-2869 ; 0891-1150
    ISSN (online) 1939-2869
    ISSN 0891-1150
    DOI 10.3949/ccjm.91a.23082
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  2. Article ; Online: Editorial: Viral Infections at the Maternal-Fetal Interface-Setting the Research Agenda.

    Bebell, Lisa M / Zash, Rebecca

    The Journal of infectious diseases

    2021  Volume 224, Issue 12 Suppl 2, Page(s) S629–S630

    MeSH term(s) Female ; Humans ; Maternal Health ; Maternal-Fetal Relations ; Placentation ; Pregnancy ; Pregnancy Complications, Infectious ; Pregnancy Outcome ; Virus Diseases
    Language English
    Publishing date 2021-07-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3019-3
    ISSN 1537-6613 ; 0022-1899
    ISSN (online) 1537-6613
    ISSN 0022-1899
    DOI 10.1093/infdis/jiab356
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  3. Article ; Online: Response.

    Okin, Daniel / Alba, George A / Bebell, Lisa M / Lai, Peggy S

    Chest

    2023  Volume 163, Issue 6, Page(s) e291

    Language English
    Publishing date 2023-06-10
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2023.02.043
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  4. Article ; Online: Cough It Up: A Health Care Paradox.

    Bebell, Lisa M

    JAMA

    2016  Volume 316, Issue 14, Page(s) 1449–1450

    MeSH term(s) Biopsy ; Cost Sharing/economics ; Diagnosis, Differential ; Fees, Pharmaceutical ; Gatekeeping ; General Practice ; Humans ; Lung/pathology ; Lung Neoplasms/diagnosis ; Lung Neoplasms/drug therapy ; Male ; Medicaid/economics ; Medicaid/legislation & jurisprudence ; Medically Uninsured ; Patient Care Team ; Physician-Patient Relations ; United States
    Language English
    Publishing date 2016-10-11
    Publishing country United States
    Document type Journal Article ; Personal Narratives ; Research Support, N.I.H., Extramural
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2016.8186
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Response.

    Okin, Daniel / Huang, Ching-Ying / Alba, George A / Thompson, B Taylor / Bebell, Lisa M / Lai, Peggy S

    Chest

    2024  Volume 163, Issue 6, Page(s) e287–e288

    Language English
    Publishing date 2024-02-05
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2023.02.029
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  6. Article ; Online: Severe Acute Respiratory Syndrome Coronavirus 2 ACE2 and TMPRSS2 Receptor Protein Expression Patterns Throughout Gestation.

    Roberts, Drucilla J / Bebell, Lisa M / Edlow, Andrea G

    The Journal of infectious diseases

    2021  Volume 224, Issue Supplement_6, Page(s) S642–S646

    Abstract: We previously demonstrated that the late gestation placental expression pattern of ACE2 (the primary severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2] receptor) is localized to the villous syncytiotrophoblast (ST), usually in a polarized ... ...

    Abstract We previously demonstrated that the late gestation placental expression pattern of ACE2 (the primary severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2] receptor) is localized to the villous syncytiotrophoblast (ST), usually in a polarized membranous pattern at the ST base sparing the apical surface (that directly exposed to maternal blood). We found that the late gestation placental expression pattern of TMPRSS2 (the spike proteinase required for SARS-CoV-2 cellular infection), is usually absent in the trophoblast but is rarely, weakly expressed in the placental endothelium. We now show the developmental protein expression patterns of ACE2 and TMPRSS2 by immunohistochemistry throughout gestation, from the first through third trimester. We found that TMPRSS2 expression was rarely detectable in villous endothelium and very rarely detectable in the ST across gestation. We found that ACE2 expression varied during gestation with circumferential ST expression more common in early gestations and polarized expression more common in later gestation. Although this study is small, these preliminary results suggest that earlier gestation pregnancies may be more vulnerable to infection than later gestation pregnancies.
    MeSH term(s) Adult ; Angiotensin-Converting Enzyme 2/genetics ; Angiotensin-Converting Enzyme 2/metabolism ; COVID-19 ; Female ; Gestational Age ; Humans ; Placenta/metabolism ; Placenta/virology ; Pregnancy ; Pregnancy Complications, Infectious/metabolism ; Pregnancy Complications, Infectious/pathology ; Pregnancy Complications, Infectious/virology ; SARS-CoV-2/metabolism ; Serine Endopeptidases/genetics ; Serine Endopeptidases/metabolism ; Trophoblasts
    Chemical Substances ACE2 protein, human (EC 3.4.17.23) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23) ; Serine Endopeptidases (EC 3.4.21.-) ; TMPRSS2 protein, human (EC 3.4.21.-)
    Language English
    Publishing date 2021-04-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3019-3
    ISSN 1537-6613 ; 0022-1899
    ISSN (online) 1537-6613
    ISSN 0022-1899
    DOI 10.1093/infdis/jiab164
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Africa needs local solutions to face the COVID-19 pandemic.

    Boum, Yap / Bebell, Lisa M / Bisseck, Anne-Cécile Zoung-Kanyi

    Lancet (London, England)

    2021  Volume 397, Issue 10281, Page(s) 1238–1240

    MeSH term(s) Africa ; COVID-19 ; Cross-Sectional Studies ; Humans ; Pandemics/prevention & control ; SARS-CoV-2
    Language English
    Publishing date 2021-03-24
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(21)00719-4
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  8. Article: Intravenous cephalosporin versus non-cephalosporin-based prophylaxis to prevent surgical site infections in colorectal surgery patients: A systematic review and meta-analysis.

    Bowder, Alexis N / Yen, Christina F / Bebell, Lisa M / Fernandes, Alisha R

    Annals of medicine and surgery (2012)

    2021  Volume 67, Page(s) 102401

    Abstract: Background: Surgical site infection (SSI) is common in colorectal surgery patients and associated with morbidity and mortality. Guidelines recommend preoperative intravenous antimicrobial prophylaxis with aerobic and anaerobic coverage to reduce SSI ... ...

    Abstract Background: Surgical site infection (SSI) is common in colorectal surgery patients and associated with morbidity and mortality. Guidelines recommend preoperative intravenous antimicrobial prophylaxis with aerobic and anaerobic coverage to reduce SSI risk. Cephalosporin based prophylaxis (CBP) regimens are recommended as first-line prophylaxis, and non-cephalosporin based are recommended as alternative prophylaxis (AP). We evaluate the efficacy of CBP versus AP in preventing surgical site infections in colorectal surgery patients.
    Methods: A systematic review and meta-analysis was conducted of studies published between 2005 and 2020 in MEDLINE and Web of Science. Studies were excluded if intravenous antimicrobial prophylaxis was not administered, or if oral and intravenous prophylaxis were routinely co-administered. Heterogeneity was reported using the Q-statistic and I
    Results: 11 studies met inclusion criteria. AP was not associated with increased SSI risk at 30 days compared to CBP (OR 1.01, 95% CI 0.91, 1.13; OR < 1 favors AP). There was no effect size variability in subgroup analysis comparing higher-to lower-quality studies (I
    Conclusions: Meta-analysis of 11 studies of SSI risk in adult colorectal surgery patients suggest that SSI risk is similar for patients receiving CBP or AP, subgroup analysis of studies published since 2014 suggest increased SSI risk with AP compared to CBP.
    Language English
    Publishing date 2021-06-16
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2745440-X
    ISSN 2049-0801
    ISSN 2049-0801
    DOI 10.1016/j.amsu.2021.102401
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Case 1-2021: A 76-Year-Old Woman with Lethargy and Altered Mental Status.

    Bebell, Lisa M / Gonzalez, R Gilberto / Barczak, Amy K / Anahtar, Melis N

    The New England journal of medicine

    2021  Volume 384, Issue 2, Page(s) 166–176

    MeSH term(s) Adenocarcinoma/complications ; Aged ; Brain/diagnostic imaging ; Brain/pathology ; Cerebral Infarction/diagnostic imaging ; Cerebral Infarction/etiology ; Cerebrospinal Fluid/microbiology ; Diagnosis, Differential ; Dyspnea/etiology ; Female ; Headache/etiology ; Humans ; Lethargy/etiology ; Lung/diagnostic imaging ; Lung/pathology ; Magnetic Resonance Imaging ; Mental Disorders/etiology ; Mycobacterium tuberculosis/isolation & purification ; Radiography, Thoracic ; Stomach Neoplasms/complications ; Tomography, X-Ray Computed ; Tuberculosis, Meningeal/complications ; Tuberculosis, Meningeal/diagnosis
    Language English
    Publishing date 2021-01-26
    Publishing country United States
    Document type Case Reports ; Clinical Conference ; Journal Article
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMcpc2027084
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Negative antigen RDT and RT-PCR results do not rule out COVID-19 if clinical suspicion is strong - Authors' reply.

    Mandeng, Nadia / Fai, Karl Njuwa / Bebell, Lisa M / Boum, Yap

    The Lancet. Infectious diseases

    2021  Volume 21, Issue 9, Page(s) 1210

    MeSH term(s) Antigens, Viral ; COVID-19 ; Humans ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2 ; Sensitivity and Specificity
    Chemical Substances Antigens, Viral
    Language English
    Publishing date 2021-05-28
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(21)00288-7
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