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  1. Article ; Online: A Rare Cause of Preseptal Cellulitis: Neisseria meningitidis.

    Atay Ünal, Nursel / Bedir Demirdağ, Tuğba / Tarlan, Bercin / Polat, Meltem / Tapisiz, Anil / Tezer, Hasan

    The Pediatric infectious disease journal

    2024  

    Language English
    Publishing date 2024-04-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000004352
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1852: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Novel coronavirus disease (COVID-19) in children

    Tezer, Hasan / Bedir Demirdağ, Tuğba

    Turkish journal of medical sciences

    2020  Volume 50, Issue SI-1, Page(s) 592–603

    Abstract: Coronavirus disease (COVID-19) was firstly reported at the end of 2019. The disease rapidly spread all around the world in a few months and was declared a worldwide pandemic by WHO in March 2020. By April 9, there were 1,436,198 confirmed COVID-19 cases ... ...

    Abstract Coronavirus disease (COVID-19) was firstly reported at the end of 2019. The disease rapidly spread all around the world in a few months and was declared a worldwide pandemic by WHO in March 2020. By April 9, there were 1,436,198 confirmed COVID-19 cases in the world, nearly with 6% mortality rate. This novel infectious disease causes respiratory tract illness that may generally occur as mild upper respiratory tract disease or pneumonia. In older patients and/or patients with underlying conditions, it may result in acute respiratory distress syndrome, multi organ failure and even death. According to the current literature, children account approximately for 1%–5% of diagnosed COVID-19 cases. Generally, COVID-19 seems to be a less severe disease for children than adults. Approximately 90% of pediatric patients are diagnosed as asymptomatic, mild, or moderate disease. However, up to 6.7% of cases may be severe. Severe illness is generally seen in patients smaller than 1 year of age and patients who have underlying disesases. The epidemiological and clinical patterns of COVID-19 and treatment approaches in pediatric patients still remain unclear although many pediatric reports are published. This review aims to summarize the current epidemics, clinical presentations, diagnosis, and treatment of COVID-19 in pediatric patients.
    MeSH term(s) Adolescent ; Antiviral Agents/therapeutic use ; Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Child ; Child, Preschool ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; Coronavirus Infections/drug therapy ; Coronavirus Infections/physiopathology ; Coronavirus Infections/therapy ; Humans ; Infant ; Infant, Newborn ; Pandemics ; Pediatrics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/therapy ; Respiratory Therapy ; Risk Factors ; SARS-CoV-2 ; COVID-19 Drug Treatment
    Chemical Substances Antiviral Agents
    Keywords covid19
    Language English
    Publishing date 2020-04-21
    Publishing country Turkey
    Document type Journal Article ; Review
    ZDB-ID 1183461-4
    ISSN 1303-6165 ; 1300-0144
    ISSN (online) 1303-6165
    ISSN 1300-0144
    DOI 10.3906/sag-2004-174
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3242: Show issues Location:
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  3. Article ; Online: A Case of Late Congenital Syphilis.

    Atay Ünal, Nursel / Kara Ulu, Nursel / Güdeloğlu, Elif / Bedir Demirdağ, Tuğba / Polat, Meltem / Tezer, Hasan / Tapisiz, Anil

    The Pediatric infectious disease journal

    2024  

    Language English
    Publishing date 2024-04-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000004377
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1852: Show issues Location:
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  4. Article: Novel coronavirus disease (COVID-19) in children

    Tezer, Hasan / Bedir Demirdag, Tugba

    Turk J Med Sci

    Abstract: Coronavirus disease (COVID-19) was firstly reported at the end of 2019. The disease rapidly spread all around the world in a few months and was declared a worldwide pandemic by WHO in March 2020. By April 9, there were 1,436,198 confirmed COVID-19 cases ... ...

    Abstract Coronavirus disease (COVID-19) was firstly reported at the end of 2019. The disease rapidly spread all around the world in a few months and was declared a worldwide pandemic by WHO in March 2020. By April 9, there were 1,436,198 confirmed COVID-19 cases in the world, nearly with 6% mortality rate. This novel infectious disease causes respiratory tract illness that may generally occur as mild upper respiratory tract disease or pneumonia. In older patients and/or patients with underlying conditions, it may result in acute respiratory distress syndrome, multi organ failure and even death. According to the current literature, children account approximately for 1%­5% of diagnosed COVID-19 cases. Generally, COVID-19 seems to be a less severe disease for children than adults. Approximately 90% of pediatric patients are diagnosed as asymptomatic, mild, or moderate disease. However, up to 6.7% of cases may be severe. Severe illness is generally seen in patients smaller than 1 year of age and patients who have underlying disesases. The epidemiological and clinical patterns of COVID-19 and treatment approaches in pediatric patients still remain unclear although many pediatric reports are published. This review aims to summarize the current epidemics, clinical presentations, diagnosis, and treatment of COVID-19 in pediatric patients.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #71833
    Database COVID19

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  5. Article ; Online: Congenital Rubella syndrome: A short report and literature review.

    Gudeloglu, Elif / Akillioglu, Merve / Bedir Demirdag, Tugba / Unal, Nursel Atay / Tapisiz, Anil Aktas

    Tropical doctor

    2022  Volume 53, Issue 1, Page(s) 171–175

    Abstract: Rubella infections are rarely seen where immunization programmes are in place. Congenital rubella syndrome is however still observed where the vaccination programme against rubella is not administered or interrupted. We present such a case, with typical ... ...

    Abstract Rubella infections are rarely seen where immunization programmes are in place. Congenital rubella syndrome is however still observed where the vaccination programme against rubella is not administered or interrupted. We present such a case, with typical clinical anomalies including congenital cataracts, sensorineural hearing loss and bone lesions. The diagnosis was verified by detection of rubella immunoglobulin M positivity in the mother in the first trimester and positive rubella serology in both baby and mother.
    MeSH term(s) Infant ; Female ; Humans ; Rubella Syndrome, Congenital/diagnosis ; Rubella Syndrome, Congenital/prevention & control ; Rubella/diagnosis ; Rubella/prevention & control ; Immunization ; Vaccination ; Mothers
    Language English
    Publishing date 2022-11-01
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 193169-6
    ISSN 1758-1133 ; 0049-4755
    ISSN (online) 1758-1133
    ISSN 0049-4755
    DOI 10.1177/00494755221134327
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    Zs.A 1056: Show issues Location:
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  6. Article ; Online: A pediatric case series of invasive pneumococcal disease caused by

    Cura Yayla, Burcu Ceylan / Bedir Demirdag, Tugba / Akkuzu, Emine / Kara, Nursel / Tezer, Hasan / Tapisiz, Anıl

    Human vaccines & immunotherapeutics

    2023  Volume 19, Issue 2, Page(s) 2219186

    Abstract: Streptococcus ... ...

    Abstract Streptococcus pneumoniae
    MeSH term(s) Child ; Humans ; Infant ; Serogroup ; Pneumococcal Infections/microbiology ; Streptococcus pneumoniae ; Pneumococcal Vaccines ; Pneumonia ; Vaccination ; Vaccines, Conjugate
    Chemical Substances Pneumococcal Vaccines ; Vaccines, Conjugate
    Language English
    Publishing date 2023-06-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2664176-8
    ISSN 2164-554X ; 2164-5515
    ISSN (online) 2164-554X
    ISSN 2164-5515
    DOI 10.1080/21645515.2023.2219186
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    Zs.A 6967: Show issues Location:
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  7. Article ; Online: Relationship between biologic modifying agents and development of latent tuberculosis in pediatrics.

    Bedir Demirdag, Tugba / Ozkaya Parlakay, Aslinur / Aydin, Fatma / Tugcu, Gokcen Dilsa / Santaflıoglu, Beytullah / Kanik Yuksek, Saliha / Gulhan, Belgin / Cinel, Guzin / Celikel Acar, Banu

    Journal of infection in developing countries

    2024  Volume 18, Issue 1, Page(s) 116–121

    Abstract: Introduction: Biologic modifying agents are associated with an increased risk for infection with mycobacteria. The aim of this study is to document patients who received different biologic modifying therapies in our pediatric rheumatology department and ...

    Abstract Introduction: Biologic modifying agents are associated with an increased risk for infection with mycobacteria. The aim of this study is to document patients who received different biologic modifying therapies in our pediatric rheumatology department and the possibility of development of tuberculosis (TB).
    Methodology: This retrospective study was conducted in Ankara City Hospital. Pediatric patients who were treated with biologic modifying agents between 2010-2020 were documented. Development of TB and the risk factors were assessed in this patient group.
    Results: There were 72 patients who were treated with different biologic modifying agents. Tuberculin skin test (TST) was positive in 7 (9.7%) patients during follow up. Three patients whose TST was positive had received canakinumab, 2 received etanercept, 1 received adalimumab and 1 received anakinra. Median duration of therapy was 43.5 (16.5-168) months for these patients and the duration was longer than patients who did not develop latent tuberculosis (p = 0.04). Patients who developed latent TB under treatment were significantly older than the patients who did not (p = 0.01).
    Conclusions: According to our findings, 9.7% of pediatric patients who received biologic modifying agent therapy developed latent TB. Patients who developed latent TB were older, and the duration of treatment was longer than patients who did not develop latent TB. Although not statistically significant, canakinumab, which is known as an agent less likely to cause TST conversion, was in fact the most common agent that caused TST conversion.
    MeSH term(s) Humans ; Child ; Latent Tuberculosis/diagnosis ; Latent Tuberculosis/drug therapy ; Latent Tuberculosis/epidemiology ; Retrospective Studies ; Interferon-gamma Release Tests ; Adalimumab ; Tuberculin Test ; Tuberculosis/drug therapy ; Biological Products/adverse effects
    Chemical Substances Adalimumab (FYS6T7F842) ; Biological Products
    Language English
    Publishing date 2024-01-31
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2394024-4
    ISSN 1972-2680 ; 2036-6590
    ISSN (online) 1972-2680
    ISSN 2036-6590
    DOI 10.3855/jidc.18000
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  8. Article ; Online: Persistent Rhinovirus Infection in a Child With Leukemia.

    Özbek Siddiqui, Duygu / Bedir Demirdağ, Tuğba / Karamercan, Sirma / Kirkiz Kayali, Serap / Kaya, Zühre / Koçak, Ülker

    Journal of pediatric hematology/oncology

    2022  Volume 45, Issue 1, Page(s) e119–e120

    Abstract: Human Rhinovirus (HRV) is one of the most common pathogens causing acute respiratory tract infections in infants and children. Several reports suggest that HRV has the potential to cause chronic infection after an acute viral infection in an ... ...

    Abstract Human Rhinovirus (HRV) is one of the most common pathogens causing acute respiratory tract infections in infants and children. Several reports suggest that HRV has the potential to cause chronic infection after an acute viral infection in an immunosuppressed patient. Although chronic HRV infection has been reported in lung transplant recipients, patients with hypogammaglobulinemia and cystic fibrosis, the duration and severity of HRV infection remain unclear. In this study, we present a case of persistent HRV infection in a stem cell transplanted leukemia patient. This report raises several questions regarding the risk factors, duration, and severity of persistent HRV infection in acute leukemia patients, which warrants prospective and longitudinal studies.
    MeSH term(s) Infant ; Humans ; Child ; Rhinovirus ; Prospective Studies ; Persistent Infection ; Picornaviridae Infections/complications ; Enterovirus Infections ; Respiratory Tract Infections/etiology ; Enterovirus ; Leukemia/complications ; Leukemia/therapy
    Language English
    Publishing date 2022-03-30
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1231152-2
    ISSN 1536-3678 ; 1077-4114 ; 0192-8562
    ISSN (online) 1536-3678
    ISSN 1077-4114 ; 0192-8562
    DOI 10.1097/MPH.0000000000002459
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    Zs.A 1537: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article ; Online: The effect of apoprotein E gene polymorphism on neurocognitive functions of children with CHD.

    Bedir Demirdag, Tugba / Gucuyener, Kivilcim / Soysal, A Sebnem / Guntekin Ergun, Sezen / Ozturk, Zeynep / Ergun, Mehmet Ali / Tunaoğlu, Sedef

    Cardiology in the young

    2022  Volume 33, Issue 9, Page(s) 1556–1560

    Abstract: Studies have demonstrated an association between CHD and neurodevelopmental delay. This delay is associated with many factors like reduced blood flow and oxygen, cardiac catheterisations, and genetic factors. Apo E gene polymorphism is one of these ... ...

    Abstract Studies have demonstrated an association between CHD and neurodevelopmental delay. This delay is associated with many factors like reduced blood flow and oxygen, cardiac catheterisations, and genetic factors. Apo E gene polymorphism is one of these genetic factors. This study aims to show the effect of Apo E gene polymorphism on neurodevelopmental process in children having CHD. A total of 188 children having CHD were admitted to the study. Apo E gene polymorphism of these patients was determined, and psychometric evaluation was performed. The relationship between psychometric test results and gene polymorphism was evaluated. This study shows that, similar to the literature, patients having cyanotic CHD have worse scores than acyanotic patients, and the children with CHD are under risk in terms of neuropsychiatric disorders. Other novel and important findings of this study were the lower verbal scores of ε2 allele carriers than ε4 carriers in Wechsler Intelligence Scale for Children-Revised group and the worse test score of patients having VSD than other acyanotic patients. Besides, some special disorders may be seen in this patient group.
    MeSH term(s) Child ; Humans ; Alleles ; Apolipoproteins E/genetics ; Cyanosis ; Heterozygote ; Polymorphism, Genetic
    Chemical Substances Apolipoproteins E
    Language English
    Publishing date 2022-09-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 1078466-4
    ISSN 1467-1107 ; 1047-9511
    ISSN (online) 1467-1107
    ISSN 1047-9511
    DOI 10.1017/S1047951122002621
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4050: Show issues Location:
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  10. Article ; Online: Multisystem inflammatory syndrome in children or invasive bacterial infection?

    Atay Ünal, Nursel / Bedir Demirdağ, Tuğba / İncedere, Fatma / Karakaş, Mutlu / Tapısız, Anıl / Tezer, Hasan / Çağlar, Kayhan / Gücüyener, Kıvılcım

    Journal of paediatrics and child health

    2022  Volume 58, Issue 10, Page(s) 1880–1882

    MeSH term(s) Bacterial Infections/diagnosis ; COVID-19/complications ; Child ; Humans ; SARS-CoV-2 ; Systemic Inflammatory Response Syndrome
    Language English
    Publishing date 2022-05-26
    Publishing country Australia
    Document type Case Reports
    ZDB-ID 1024476-1
    ISSN 1440-1754 ; 1034-4810
    ISSN (online) 1440-1754
    ISSN 1034-4810
    DOI 10.1111/jpc.16022
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    Zs.A 227: Show issues Location:
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