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  1. Article: Réinnervations laryngées.

    Salati, Victoria / Beharry, Avinash / Fries, Sophie / Sandu, Kishore / Gorostidi, François

    Revue medicale suisse

    2020  Volume 16, Issue 709, Page(s) 1845–1848

    Abstract: The surgical management of unilateral and bilateral vocal cord paralysis depends on the severity of the condition, the potential for spontaneous recovery, the patient's age and vocal expectations. Standardized re-innervation surgeries, unilateral non- ... ...

    Title translation Laryngeal reinnervation.
    Abstract The surgical management of unilateral and bilateral vocal cord paralysis depends on the severity of the condition, the potential for spontaneous recovery, the patient's age and vocal expectations. Standardized re-innervation surgeries, unilateral non-selective and bilateral selective, are viable alternatives to static procedures currently under evaluation in prospective studies. Neurorraphy of the ansa cervicalis loop to the recurrent laryngeal nerve allows lasting vocal recovery and potentially superior results to medialization and thyroplasty, by maintaining the visco-elastic properties of the vocal cord and preventing its atrophy. Selective bilateral reinnervation shows potential for recovery of inspiratory abduction with improved respiratory function without vocal deterioration.
    MeSH term(s) Humans ; Larynx/surgery ; Prospective Studies ; Recurrent Laryngeal Nerve/surgery ; Vocal Cord Paralysis/surgery ; Vocal Cords/surgery
    Language French
    Publishing date 2020-10-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5998: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: The robotic-assisted extended "Sistrunk" approach for tumors of the upper aerodigestive tract with limited transoral access: First description of oncological and functional outcomes.

    Simon, Christian / Beharry, Avinash / Paleri, Vinidh / Dübi, Pascaline / Lambercy, Karma / Holsinger, F Christopher / Todic, Jelena

    Head & neck

    2022  Volume 44, Issue 10, Page(s) 2335–2341

    Abstract: We report on the first clinical experience with the robotic-assisted extended "Sistrunk" approach (RESA) for access to constrained spaces of the upper aerodigestive tract. This prospective case cohort study include six patients that underwent RESA if ... ...

    Abstract We report on the first clinical experience with the robotic-assisted extended "Sistrunk" approach (RESA) for access to constrained spaces of the upper aerodigestive tract. This prospective case cohort study include six patients that underwent RESA if transoral exposure could not be achieved. Three patients received previous radiation. Patients were postoperatively followed until week 16 for perioperative complications, surgical margins, and functional outcomes. In all patients RESA allowed adequate exposure and resection with negative margins. Three patients who underwent salvage surgery experienced a minor or intermediate grade postoperative bleeding. No patient developed a pharyngocutaneous fistula. Three patients recovered their swallowing to their preoperative status and the remaining three experienced an improvement. All patients experienced complete recovery of their voice. RESA has the potential to provide a new organ preservation approach for head and neck cancer (HNC) not amenable to transoral exposure and thus warrants further prospective clinical studies.
    MeSH term(s) Cohort Studies ; Head and Neck Neoplasms/surgery ; Humans ; Margins of Excision ; Robotic Surgical Procedures ; Robotics
    Language English
    Publishing date 2022-06-02
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 645165-2
    ISSN 1097-0347 ; 0148-6403 ; 1043-3074
    ISSN (online) 1097-0347
    ISSN 0148-6403 ; 1043-3074
    DOI 10.1002/hed.27114
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1493: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  3. Article ; Online: Predictive Factors of Swallowing Disorders and Bronchopneumonia in Acute Ischemic Stroke.

    Beharry, Avinash / Michel, Patrik / Faouzi, Mohamed / Kuntzer, Thierry / Schweizer, Valérie / Diserens, Karin

    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

    2019  Volume 28, Issue 8, Page(s) 2148–2154

    Abstract: Background: In stroke patients, early complications such as swallowing disorders (SD) and bronchopneumonia (BP) are frequent and may worsen outcome. The aim of this study was to evaluate the prevalence of SD in acute ischemic stroke (AIS) and the risk ... ...

    Abstract Background: In stroke patients, early complications such as swallowing disorders (SD) and bronchopneumonia (BP) are frequent and may worsen outcome. The aim of this study was to evaluate the prevalence of SD in acute ischemic stroke (AIS) and the risk of BP, as well as to identify factors associated with these conditions.
    Methods: We retrospectively studied all AISs over a 12-month period in a single-center registry. We determined the frequency of SD in the first 7 days and of BP over the entire hospital stay. Associations of SD and BP with patient characteristics, stroke features, dental status, and presence of a feeding tube were analyzed in multivariate analyses.
    Results: In the 340 consecutive patients, the overall frequency of SD and BP was 23.8% and 11.5%, respectively. The multivariate analyses showed significant associations of SD with NIHSS scores >4, involvement of the medulla oblongata and wearing a dental prosthesis (area under the receiver-operator curve (AUC) of 76%). BP was significantly associated with NIHSS scores >4, male sex, bilateral cerebral lesions, the presence of SD, and the use of an enteral feeding tube (AUC 84%). In unadjusted analysis, unfavorable 12-month outcome and mortality were increased in the presence of SD.
    Conclusion: In AIS, SD and BP are associated with stroke severity and localization and wearing a dental prosthesis increases the risk of SD. Given that patients with SD have an increased risk of poor outcome and mortality, high-risk patients warrant early interventions, including more randomized trials.
    MeSH term(s) Aged ; Aged, 80 and over ; Brain Ischemia/diagnosis ; Brain Ischemia/epidemiology ; Brain Ischemia/physiopathology ; Bronchopneumonia/diagnosis ; Bronchopneumonia/epidemiology ; Deglutition ; Deglutition Disorders/diagnosis ; Deglutition Disorders/epidemiology ; Deglutition Disorders/physiopathology ; Dental Prosthesis/adverse effects ; Enteral Nutrition/adverse effects ; Female ; Hospitalization ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Prevalence ; Prognosis ; Registries ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Severity of Illness Index ; Sex Factors ; Stroke/diagnosis ; Stroke/epidemiology ; Stroke/physiopathology ; Time Factors
    Language English
    Publishing date 2019-05-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1131675-5
    ISSN 1532-8511 ; 1052-3057
    ISSN (online) 1532-8511
    ISSN 1052-3057
    DOI 10.1016/j.jstrokecerebrovasdis.2019.04.025
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    Zs.A 3519: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  4. Article ; Online: Transoral Robotic Surgery for Recurrent Tumors of the Upper Aerodigestive Tract (RECUT): An International Cohort Study.

    Hardman, John C / Holsinger, F Chris / Brady, Grainne C / Beharry, Avinash / Bonifer, Alec T / D'Andréa, Gregoire / Dabas, Surender K / de Almeida, John R / Duvvuri, Umamaheswar / Floros, Peter / Ghanem, Tamer A / Gorphe, Philippe / Gross, Neil D / Hamilton, David / Kurukulasuriya, Chareeni / Larsen, Mikkel Hjordt Holm / Lin, Daniel J / Magnuson, J Scott / Meulemans, Jeroen /
    Miles, Brett A / Moore, Eric J / Pantvaidya, Gouri / Roof, Scott / Rubek, Niclas / Simon, Christian / Subash, Anand / Topf, Michael C / Van Abel, Kathryn M / Vander Poorten, Vincent / Walgama, Evan S / Greenlay, Emily / Potts, Laura / Balaji, Arun / Starmer, Heather M / Stephen, Sarah / Roe, Justin / Harrington, Kevin / Paleri, Vinidh

    Journal of the National Cancer Institute

    2022  Volume 114, Issue 10, Page(s) 1400–1409

    Abstract: Background: Transoral robotic surgery (TORS) is an emerging minimally invasive surgical treatment for residual, recurrent, and new primary head and neck cancers in previously irradiated fields, with limited evidence for its oncological effectiveness.: ...

    Abstract Background: Transoral robotic surgery (TORS) is an emerging minimally invasive surgical treatment for residual, recurrent, and new primary head and neck cancers in previously irradiated fields, with limited evidence for its oncological effectiveness.
    Methods: A retrospective observational cohort study of consecutive cases performed in 16 high-volume international centers before August 2018 was conducted (registered at clinicaltrials.gov [NCT04673929] as the RECUT study). Overall survival (OS), disease-free survival, disease-specific survivals (DSS), and local control (LC) were calculated using Kaplan-Meier estimates, with subgroups compared using log-rank tests and Cox proportional hazards modeling for multivariable analysis. Maximally selected rank statistics determined the cut point for closest surgical resection margin based on LC.
    Results: Data for 278 eligible patients were analyzed, with median follow-up of 38.5 months. Two-year and 5-year outcomes were 69.0% and 62.2% for LC, 71.8% and 49.8% for OS, 47.2% and 35.7% for disease-free survival, and 78.7% and 59.1% for disease-specific survivals. The most discriminating margin cut point was 1.0 mm; the 2-year LC was 80.9% above and 54.2% below or equal to 1.0 mm. Increasing age, current smoking, primary tumor classification, and narrow surgical margins (≤1.0 mm) were statistically significantly associated with lower OS. Hemorrhage with return to theater was seen in 8.1% (n = 22 of 272), and 30-day mortality was 1.8% (n = 5 of 272). At 1 year, 10.8% (n = 21 of 195) used tracheostomies, 33.8% (n = 66 of 195) used gastrostomies, and 66.3% (n = 53 of 80) had maintained or improved normalcy of diet scores.
    Conclusions: Data from international centers show TORS to treat head and neck cancers in previously irradiated fields yields favorable outcomes for LC and survival. Where feasible, TORS should be considered the preferred surgical treatment in the salvage setting.
    MeSH term(s) Carcinoma, Squamous Cell/pathology ; Cohort Studies ; Head and Neck Neoplasms/surgery ; Humans ; Margins of Excision ; Natural Orifice Endoscopic Surgery ; Oropharyngeal Neoplasms ; Retrospective Studies ; Robotic Surgical Procedures/adverse effects ; Treatment Outcome
    Language English
    Publishing date 2022-08-10
    Publishing country United States
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 2992-0
    ISSN 1460-2105 ; 0027-8874 ; 0198-0157
    ISSN (online) 1460-2105
    ISSN 0027-8874 ; 0198-0157
    DOI 10.1093/jnci/djac130
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh III Zs.131: Show issues Location:
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