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  1. Article ; Online: Melatonin Relations with Energy Metabolism as Possibly Involved in Fatal Mountain Road Traffic Accidents.

    Behn, Claus / De Gregorio, Nicole

    International journal of molecular sciences

    2020  Volume 21, Issue 6

    Abstract: Previous results evidenced acute exposure to high altitude (HA) weakening the relation between daily melatonin cycle and the respiratory quotient. This review deals with the threat extreme environments pose on body time order, particularly concerning ... ...

    Abstract Previous results evidenced acute exposure to high altitude (HA) weakening the relation between daily melatonin cycle and the respiratory quotient. This review deals with the threat extreme environments pose on body time order, particularly concerning energy metabolism. Working at HA, at poles, or in space challenge our ancestral inborn body timing system. This conflict may also mark many aspects of our current lifestyle, involving shift work, rapid time zone crossing, and even prolonged office work in closed buildings. Misalignments between external and internal rhythms, in the short term, traduce into risk of mental and physical performance shortfalls, mood changes, quarrels, drug and alcohol abuse, failure to accomplish with the mission and, finally, high rates of fatal accidents. Relations of melatonin with energy metabolism being altered under a condition of hypoxia focused our attention on interactions of the indoleamine with redox state, as well as, with autonomic regulations. Individual tolerance/susceptibility to such interactions may hint at adequately dealing with body timing disorders under extreme conditions.
    MeSH term(s) Accidents, Traffic ; Altitude ; Animals ; Circadian Rhythm ; Energy Metabolism ; Humans ; Melatonin/metabolism
    Chemical Substances Melatonin (JL5DK93RCL)
    Language English
    Publishing date 2020-03-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms21062184
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Varicocele at High Altitude; Venous Outflow Restriction by Hypobaric Hypoxia.

    Alcántara-Zapata, Diana / Nazzal, Carolina / Muñoz, Sergio / De Gregorio, Nicole / Marchetti, Nella / Behn, Claus

    Current vascular pharmacology

    2022  Volume 20, Issue 3, Page(s) 303–309

    Abstract: Background: Testicular aches have been reported to occur on exposure to high altitude (HA). As a painful expression of venous congestion at the pampiniform plexus, varicocele (VC) might be a consequence of cardiovascular adjustments at HA. Chile's ... ...

    Abstract Background: Testicular aches have been reported to occur on exposure to high altitude (HA). As a painful expression of venous congestion at the pampiniform plexus, varicocele (VC) might be a consequence of cardiovascular adjustments at HA. Chile's National Social Security Regulatory Body (SUSESO) emphasized evaluating this condition in the running follow-up study "Health effects of exposure to chronic intermittent hypoxia in Chilean mining workers."
    Objectives: This study aimed at investigating the prevalence of VC in a population usually shifting between sea level and HA, thereby intermittently being exposed to hypobaric hypoxia.
    Methodology: Miners (n=492) agreed to be examined at their working place by a physician, in the context of a general health survey, for the presence of palpable VC, either visible or not. Among them was a group exposed to low altitude (LA) <2,400 m; n=123; another one exposed to moderate high altitude (MHA) working 3,050 m; n=70, and a third one exposed to very high altitude (VHA) >3,900 m, n=165. The Chi
    Results: VC prevalence (grades 2 and 3) was found to be 10% at LA, 4.1% at MHA, and 16.7% at VHA (p≤0.05). Hemoglobin oxygen saturation (SaO
    Conclusion: Association of VC with HA, a clinically relevant finding, may be related to blood volume centralization mediated by hypobaric hypoxia.
    MeSH term(s) Altitude ; Follow-Up Studies ; Hemoglobins ; Humans ; Hypoxia/epidemiology ; Male ; Varicocele/complications ; Varicocele/diagnosis ; Varicocele/epidemiology
    Chemical Substances Hemoglobins
    Language English
    Publishing date 2022-05-11
    Publishing country United Arab Emirates
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2192362-0
    ISSN 1875-6212 ; 1570-1611
    ISSN (online) 1875-6212
    ISSN 1570-1611
    DOI 10.2174/1570161120666220510120831
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Thesis: Physikalisch-technologische Eigenschaften von unterschiedlich verleimten Recyclingspan- und -faserplatten

    Behn, Claus

    2006  

    Title variant Recyclingspanplatten Recyclingfaserplatten
    Author's details vorgelegt von Claus Behn
    Keywords Recycling ; Quellung ; Faserplatte ; Altholz ; Spanplatte ; Feuchtigkeit ; Dimensionsstabilität
    Language German
    Size VII, 144 S, Ill., graph. Darst, 21 cm
    Edition 1. Aufl
    Publisher Cuvillier
    Publishing place Göttingen
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Göttingen, 2005
    ISBN 386727987X ; 9783867279871
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  4. Book ; Thesis: Physikalisch-technologische Eigenschaften von unterschiedlich verleimten Recyclingspan- und -faserplatten

    Behn, Claus

    2006  

    Title variant Recyclingspanplatten Recyclingfaserplatten
    Author's details vorgelegt von Claus Behn
    Keywords Recycling ; Quellung ; Faserplatte ; Altholz ; Spanplatte ; Feuchtigkeit ; Dimensionsstabilität
    Language German
    Size VII, 144 S, Ill., graph. Darst, 21 cm
    Edition 1. Aufl
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Zugl.: Göttingen, Univ., Diss., 2005
    ISBN 386727987X ; 9783867279871
    Database Johann Heinrich von Thünen-Institut, Federal Research Institute for Rural Areas, Forestry and Fisheries

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  5. Book ; Online: Untersuchungen zur Verminderung der Längenänderung von Holzspanplatten durch gezielte Nutzung von materialimmanenten Eigenschaften und Verwendung von feuchtebeständigen Zusatzstoffen

    Behn, Claus / Roffael, E

    Schlussbericht ; Laufzeit: 01.07.1999 bis 31.08.2003

    2004  

    Author's details [E. Roffael; C. Behn]
    Language German
    Size Online-Ressource (108 S., 3,12 MB), Ill., graph. Darst., Tab
    Publisher Technische Informationsbibliothek u. Universitätsbibliothek ; Inst. f. Holzbiologie u. Holztechnologie, Lehrbereich Holzchemie u. Holztechnologie, Univ
    Publishing place Hannover ; Göttingen
    Document type Book ; Online
    Note Förderkennzeichen BMBF 0339851 8. - Literaturverz. ; IMD-Felder maschinell generiert ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  6. Book: Untersuchungen zur Verminderung der Längenänderung von Holzspanplatten durch gezielte Nutzung von materialimmanenten Eigenschaften und Verwendung von feuchtebeständigen Zusatzstoffen

    Roffael, Edmone / Behn, Claus

    Schlussbericht ; Laufzeit: 01.07.1999 bis 31.08.2003

    2004  

    Author's details [Autoren des Berichts: Roffael, Edmone; Behn, Claus]
    Language German
    Size 103 Bl, Ill., graph. Darst
    Publisher Univ., Inst. f. Holzbiologie u. Holztechnologie, Lehrbereich Holzchemie u. Holztechnologie
    Publishing place Göttingen
    Document type Book
    Note Förderkennzeichen BMBF 0339851/8. - Literaturverz. Bl. 92 - 97 ; Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  7. Article ; Online: Melatonin and sleep responses to normobaric hypoxia and aerobic physical exercise: A randomized controlled trial.

    de Aquino Lemos, Valdir / Dos Santos, Ronaldo Vagner Thomatieli / Antunes, Hanna Karen Moreira / Behn, Claus / Viscor, Gines / Lira, Fabio Santos / Bittar, Irene Guarido Luz / Caris, Aline Venticinque / Tufik, Sergio / De Mello, Marco Tulio

    Physiology & behavior

    2018  Volume 196, Page(s) 95–103

    Abstract: This work evaluated the effects of moderate physical exercise performed under hypoxic conditions on melatonin and sleep. Forty healthy men were randomized into four groups: Normoxia (N) (n = 10); Hypoxia (H) (n = 10); Exercise under Normoxia (EN) (n = 10) ...

    Abstract This work evaluated the effects of moderate physical exercise performed under hypoxic conditions on melatonin and sleep. Forty healthy men were randomized into four groups: Normoxia (N) (n = 10); Hypoxia (H) (n = 10); Exercise under Normoxia (EN) (n = 10); and Exercise under Hypoxia (EH) (n = 10). The observation period for all groups was approximately 36 h, beginning with a first night devoid of any intervention. Aerobic exercise was performed by the EN and EH groups on a treadmill at 50% of the ventilatory threshold intensity for 60 min. Sleep evaluation was performed on the 1st and 2nd nights. Venous blood samples for the melatonin measurement were obtained on the 1st and 2nd days at 7:30 AM as well as on the 1st and 2nd nights at 10:30 PM. On the 2nd night, melatonin was higher in the H group than in the N group, but both were lower than values of the EH group. The nocturnal increase in melatonin was inversely correlated with the oxygen saturation of hemoglobin (SaO
    MeSH term(s) Adult ; Exercise/physiology ; Humans ; Hypoxia/physiopathology ; Male ; Melatonin/blood ; Oxygen/blood ; Photoperiod ; Sleep/physiology ; Young Adult
    Chemical Substances Melatonin (JL5DK93RCL) ; Oxygen (S88TT14065)
    Language English
    Publishing date 2018-08-29
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 3907-x
    ISSN 1873-507X ; 0031-9384
    ISSN (online) 1873-507X
    ISSN 0031-9384
    DOI 10.1016/j.physbeh.2018.08.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Melatonin Relations With Respiratory Quotient Weaken on Acute Exposure to High Altitude.

    Tapia, Marcelo / Wulff-Zottele, Cristian / De Gregorio, Nicole / Lang, Morin / Varela, Héctor / Josefa Serón-Ferré, María / Vivaldi, Ennio A / Araneda, Oscar F / Silva-Urra, Juan / Gunga, Hanns-Christian / Behn, Claus

    Frontiers in physiology

    2018  Volume 9, Page(s) 798

    Abstract: High altitude (HA) exposure may affect human health and performance by involving the body timing system. Daily variations of melatonin may disrupt by HA exposure, thereby possibly affecting its relations with a metabolic parameter like the respiratory ... ...

    Abstract High altitude (HA) exposure may affect human health and performance by involving the body timing system. Daily variations of melatonin may disrupt by HA exposure, thereby possibly affecting its relations with a metabolic parameter like the respiratory quotient (RQ). Sea level (SL) volunteers (7 women and 7 men, 21.0 ± 2.04 y) were examined for daily changes in salivary melatonin concentration (SMC). Sampling was successively done at SL (Antofagasta, Chile) and, on acute HA exposure, at nearby Caspana (3,270 m asl). Saliva was collected in special vials (Salimetrics Oral Swab, United Kingdom) at sunny noon (SMC
    Language English
    Publishing date 2018-06-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2018.00798
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Antioxidant capacity and oxidative damage determination in synovial fluid of chronically damaged equine metacarpophalangeal joint

    Villasante, Alejandro / Araneda, Oscar F / Behn, Claus / Galleguillos, Marco / Adarmes, Hector

    Veterinary research communications. 2010 Feb., v. 34, no. 2

    2010  

    Abstract: In order to determine oxidative stress in equine joints with degenerative processes, we analyzed synovial fluid (SF) antioxidant capacity and the concentration of oxidative damage biomarkers in healthy and chronically damaged metacarpophalangeal joints. ... ...

    Abstract In order to determine oxidative stress in equine joints with degenerative processes, we analyzed synovial fluid (SF) antioxidant capacity and the concentration of oxidative damage biomarkers in healthy and chronically damaged metacarpophalangeal joints. SF samples were collected from joints of thirty 2-5 year-old crossbreed male equine, macroscopically classified at post mortem inspection and later histologically confirmed. The antioxidant capacity was determined measuring uric acid and the concentration of sulfhydryl groups and the total radical trapping antioxidant potential (TRAP). The oxidative damage was determined by assessing malondialdehyde (MDA) and carbonyl protein concentration. TRAP was significantly higher (p < 0.05) in the group with chronic damage (CD). The sulfhydryl groups and concentration of uric acid did not show significant difference between the groups (p > 0.05). Although carbonyl concentration did not show significant difference between groups, it was slightly higher in the group with CD (p = 0.05009). Concentration of MDA did not show significant difference (p > 0.05) between groups. The observed significant increase in TRAP in the group with CD could be related to the participation of components other than protein, sulfhydryl groups, or uric acid coming from degenerating joint tissues. These findings could be helpful for a better understanding of the oxidative stress role in equine joints with chronic degenerative process.
    Keywords horses ; horse diseases ; joint diseases ; chronic diseases ; synovial fluid ; antioxidant activity ; oxidative stress ; biomarkers ; histopathology ; malondialdehyde ; sulfhydryl groups
    Language English
    Dates of publication 2010-02
    Size p. 133-141.
    Publisher Springer Netherlands
    Publishing place Dordrecht
    Document type Article
    ZDB-ID 406735-6
    ISSN 1573-7446 ; 0165-7380
    ISSN (online) 1573-7446
    ISSN 0165-7380
    DOI 10.1007/s11259-009-9338-9
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Antioxidant capacity and oxidative damage determination in synovial fluid of chronically damaged equine metacarpophalangeal joint.

    Villasante, Alejandro / Araneda, Oscar F / Behn, Claus / Galleguillos, Marco / Adarmes, Hector

    Veterinary research communications

    2009  Volume 34, Issue 2, Page(s) 133–141

    Abstract: In order to determine oxidative stress in equine joints with degenerative processes, we analyzed synovial fluid (SF) antioxidant capacity and the concentration of oxidative damage biomarkers in healthy and chronically damaged metacarpophalangeal joints. ... ...

    Abstract In order to determine oxidative stress in equine joints with degenerative processes, we analyzed synovial fluid (SF) antioxidant capacity and the concentration of oxidative damage biomarkers in healthy and chronically damaged metacarpophalangeal joints. SF samples were collected from joints of thirty 2-5 year-old crossbreed male equine, macroscopically classified at post mortem inspection and later histologically confirmed. The antioxidant capacity was determined measuring uric acid and the concentration of sulfhydryl groups and the total radical trapping antioxidant potential (TRAP). The oxidative damage was determined by assessing malondialdehyde (MDA) and carbonyl protein concentration. TRAP was significantly higher (p < 0.05) in the group with chronic damage (CD). The sulfhydryl groups and concentration of uric acid did not show significant difference between the groups (p > 0.05). Although carbonyl concentration did not show significant difference between groups, it was slightly higher in the group with CD (p = 0.05009). Concentration of MDA did not show significant difference (p > 0.05) between groups. The observed significant increase in TRAP in the group with CD could be related to the participation of components other than protein, sulfhydryl groups, or uric acid coming from degenerating joint tissues. These findings could be helpful for a better understanding of the oxidative stress role in equine joints with chronic degenerative process.
    MeSH term(s) Animals ; Antioxidants/metabolism ; Horse Diseases/metabolism ; Horses ; Joint Diseases/metabolism ; Joint Diseases/veterinary ; Male ; Malondialdehyde/metabolism ; Oxidative Stress/physiology ; Statistics, Nonparametric ; Sulfhydryl Compounds/metabolism ; Synovial Fluid/metabolism ; Uric Acid/metabolism
    Chemical Substances Antioxidants ; Sulfhydryl Compounds ; Uric Acid (268B43MJ25) ; Malondialdehyde (4Y8F71G49Q)
    Language English
    Publishing date 2009-12-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 406735-6
    ISSN 1573-7446 ; 0165-7380
    ISSN (online) 1573-7446
    ISSN 0165-7380
    DOI 10.1007/s11259-009-9338-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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