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  1. Article ; Online: The Effect of Vitamin D Deficiency on Overgrowth of Uterine Fibroids

    Fatemeh Davari Tanha / Elham Feizabad / Maryam Vasheghani Farahani / Hoora Amuzegar / Behnaz Moradi / Saghar Samimi Sadeh

    International Journal of Fertility and Sterility, Vol 15, Iss 2, Pp 95-

    A Blinded Randomized Clinical Tria

    2021  Volume 100

    Abstract: Background: To evaluate the effects of vitamin D (vitD) supplement on uterine fibroid growth.Materials and Methods: A randomized blinded clinical trial was conducted at a tertiary university-based hospitalfrom August 2017 to September 2018. Totally, 204 ... ...

    Abstract Background: To evaluate the effects of vitamin D (vitD) supplement on uterine fibroid growth.Materials and Methods: A randomized blinded clinical trial was conducted at a tertiary university-based hospitalfrom August 2017 to September 2018. Totally, 204 women were enrolled into the study. They had at least one uterinefibroid >10 mm on transvaginal ultrasound and their vitD level was insufficient (i.e. 20-30 ng/ml). The interventiongroup was treated with vitD 50000 U supplements for two months. After 2 months, ultrasound screening and vitDlevel measurement was done in both groups.Results: At first, the mean serum vitD levels in intervention and control group were 23.62 and 23.20 ng/ml, respectively.After 8 weeks, the mean serum vitD levels in the control and intervention group were 22.72 and 28.56 ng/mlrespectively (p <0.05). Also, mean fibroma diameter in the intervention group before and after 8 weeks of vitD supplementationwas 43 ± 4.68 and 42.6 ± 1.31 mm, respectively. Mean uterine fibroid diameter in the control group whichdid not receive vitD supplements, before and after 8 weeks was 41.98 ± 5.25 and 47.81 ± 3.42 mm, respectively. Thevariation in the mean size of the uterine fibroid between the control and intervention group which was respectivelyabout 5.83 mm increase and 0.48 mm decrease, was significant (p <0.001).Conclusion: Our results showed that vitD supplementation prevents fibroid growth. It seems that vitD supplementis a simple, safe and inexpensive modality for leiomyoma growth prevention (Registration number:IRCT201703122576N15).
    Keywords cell proliferation ; dietary supplements ; leiomyoma ; premenopausal women ; vitamin d ; Medicine (General) ; R5-920
    Subject code 630
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher Royan Institute (ACECR), Tehran
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Differentiation of benign and malignant breast lesions by apparent diffusion coefficient value in mass and non-mass lesions

    Masoumeh Gity / Behnaz Moradi / Rasool Arami / Ali Arabkheradmand / Mohamad Ali Kazemi

    Tehran University Medical Journal, Vol 77, Iss 1, Pp 13-

    2019  Volume 18

    Abstract: Background: Diffusion-weighted imaging (DWI) is one of methods in evaluation of breast lesions. We aimed to investigate the apparent diffusion coefficient (ADC) values in breast tumors and their accuracy in differentiating benign versus malignant lesions. ...

    Abstract Background: Diffusion-weighted imaging (DWI) is one of methods in evaluation of breast lesions. We aimed to investigate the apparent diffusion coefficient (ADC) values in breast tumors and their accuracy in differentiating benign versus malignant lesions. Methods: In this cross-sectional study, 72 patients with 88 breast lesions were investigated by 1.5-T breast MRI from 2015 to 2017 in Athari Imaging Center in Tehran, Iran. Nearly all patients has undergone histopathology evaluation. One small region of interest (ROI) were placed on the most restricted region inside the solid part on the ADC map. Care was taken to avoid cystic or necrotic, fatty regions and hematoma inside the mass. A large round ROIs were placed in healthy fibroglandular tissue of contralateral breast ADC values were measured and compared in normal breast tissue and in most restricted parts of breast lesions (mass and non-mass). After determining cut-off for differentiation of benign and malignant lesions, sensitivity, specificity, accuracy, positive predictive value and negative predictive value were calculated. Results: Mean age of patients was 43.3 years. The average tumor size of benign and malignant lesions were calculated 26.0 mm, 35.3 mm respectively and 23 mm and 46 mm in mass and non-mass respectively. Invasive ductal carcinoma include the majority of pathology result (in 37.5% of the patients). Our results revealed that the measured ADC values in normal breast tissue were higher than breast lesions (P≤0.01). Mean ADC value in benign lesions was 1.40×10-3 mm²/s and for malignant lesion was 1.08×10-3 mm²/s. ADC value in the normal breast tissue was 1.79×10-3 mm2/s and was significantly higher than ADC value of breast lesions (benign and malignant). Cut-off value in non-mass was not valid, but in mass was 1.19×10-3 mm²/s with sensitivity, specificity, positive predictive value, negative predictive and accuracy of 89.7%, 83.8%, 87.5%, 86.6%, and 87.1% respectively. Conclusion: In DWI imaging, ADC value can differentiate benign and ...
    Keywords apparent diffusion coefficient ; breast neoplasms ; diffusion-weighted imaging ; ROC curve ; Medicine (General) ; R5-920
    Subject code 616 ; 610
    Language Persian
    Publishing date 2019-04-01T00:00:00Z
    Publisher Tehran University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: A case report of prenatally detected achondrogenesis type Ⅱ with an occipital cephalocele

    Behnaz Moradi / Khadijeh Adabi / Mohamad Ali Kazemi / Farzaneh Fattahi Masrour

    Asian Pacific Journal of Reproduction, Vol 6, Iss 5, Pp 238-

    2017  Volume 240

    Abstract: Achondrogenesis is a very rare lethal skeletal disorder. Here we describe a case of prenatally diagnosed achondrogenesis type Ⅱ in a 28 year-old woman at (17+4) wk. She had history of 5 first trimester missed abortions. The couple is consanguineous. ... ...

    Abstract Achondrogenesis is a very rare lethal skeletal disorder. Here we describe a case of prenatally diagnosed achondrogenesis type Ⅱ in a 28 year-old woman at (17+4) wk. She had history of 5 first trimester missed abortions. The couple is consanguineous. Ultrasonography showed extreme micromelia, short neck and trunk, large head and prominent abdomen. Delayed ossification in sacral bones was detected and ossification of pubic rami was poor. There were associated large cystic hygroma, anasarca and also high occipital cephalocele. Posterior fossa was normal. Mild hypothelorism, depressed nasal bridge, low set ear and mild retrognathia were identified too. Amniocentesis result was compatible with a normal female fetus. Post mortem whole body radiography confirmed the diagnosis. To our knowledge, this is the second case report with association of cephalocele and achondrogenesis type Ⅱ.
    Keywords Achondrogenesis type Ⅱ ; Cephalocele ; Cystic hygroma ; Lethal skeletal dysplasia ; Medicine ; R
    Language English
    Publishing date 2017-09-01T00:00:00Z
    Publisher Hainan Medical University Journal Publisher
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Ovarian hyperstimulation syndrome followed by ovarian torsion in premenopausal patient using adjuvant tamoxifen treatment for breast cancer

    Behnaz Moradi / Mohammad Ali Kazemi / Maryam Rahamni / Masoumeh Gity

    Asian Pacific Journal of Reproduction, Vol 5, Iss 5, Pp 442-

    2016  Volume 444

    Abstract: Tamoxifen is a popular medication used in the adjuvant therapy of hormone sensitive breast cancer. In this case report we describe a 39 years old woman presented with ovarian hyperstimulation on the underlying thamoxifen treatment and consecutive ovarian ...

    Abstract Tamoxifen is a popular medication used in the adjuvant therapy of hormone sensitive breast cancer. In this case report we describe a 39 years old woman presented with ovarian hyperstimulation on the underlying thamoxifen treatment and consecutive ovarian torsion.
    Keywords Tamoxifen ; Ovarian hyperstimulation ; OHSS ; Ovarian torsion ; Medicine ; R
    Language English
    Publishing date 2016-09-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Prenatal diagnosis of concurrent facial and cerebral vascular malformation which caused congestive heart failure

    Behnaz Moradi / Ahmad-Reza Tahmasebpour / Mohamad Ali Kazemi / Hashem Sharifian / Hadi Rokni-Yazdi

    Middle East Fertility Society Journal, Vol 22, Iss 4, Pp 343-

    2017  Volume 346

    Abstract: Arteriovenous malformations (AVMs) are rarely reported antenatally. Most in utero diagnosis of vascular malformation is related to vein of Galen malformation (VGM). We describe a case of simultaneously diagnosed pial arteriovenous fistula (AVF) and ... ...

    Abstract Arteriovenous malformations (AVMs) are rarely reported antenatally. Most in utero diagnosis of vascular malformation is related to vein of Galen malformation (VGM). We describe a case of simultaneously diagnosed pial arteriovenous fistula (AVF) and facial vascular malformation in a 20 weeks old fetus. The dilated intracranial venous pouch appeared as a midline anechoic structure which was misdiagnosed as a VGM in her previous ultrasound exam. Another AVM was diagnosed in the same side of fetal face which fed by a branch of external carotid artery and communicated with the mentioned pial AVF. High output cardiac failure and hydrops were evident. To our knowledge this is the first report of prenatally detected combination of facial and cerebral vascular malformations at such as early pregnancy week.
    Keywords Arteriovenous malformation ; Pial arteriovenous fistula ; Heart failure ; Antenatal ultrasound ; Face ; Medicine (General) ; R5-920 ; Reproduction ; QH471-489
    Language English
    Publishing date 2017-12-01T00:00:00Z
    Publisher SpringerOpen
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Two Consecutive Stillbirths with Multiple Intestinal Atresias in a 30-Year-Old Female

    Nargess Tabarzan / Behnaz Moradi / Maliheh Kadivar / Fatemeh Mahjoub

    Iranian Journal of Pediatrics, Vol 19, Iss 4, Pp 435-

    2009  Volume 438

    Abstract: Background:Multiple duodenal and jejuno-ileal atresias are extremely uncommon. The familial occurrence of multiple intestinal atresias is even more unusual. Also fetal death with isolated intestinal atresia is very rare, and the combination of recurrent ... ...

    Abstract Background:Multiple duodenal and jejuno-ileal atresias are extremely uncommon. The familial occurrence of multiple intestinal atresias is even more unusual. Also fetal death with isolated intestinal atresia is very rare, and the combination of recurrent familial intestinal atresias and intra-uterine fetal death has not been reported previously. Case Presentation:We report on two cases of intra-uterine fetal death in a 30-year-old woman who is consanguineous with her husband and they have only one boy who carries chromosomal abnormality. To best of our knowledge this is the first reported case of two consecutive pregnancies with multiple intestinal atresias leading to intrauterine fetal death. Conclusion:Multiple and recurrent intestinal atresias are extremely uncommon. These rare cases may contribute to genetic mapping for intestinal atresias.
    Keywords Multiple Intestinal Atresias ; Repeated ; Consanguineous ; Marriage ; Intrauterine Fetal Death ; Familial ; Pediatrics ; RJ1-570 ; Medicine ; R ; DOAJ:Pediatrics ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Subject code 610
    Language English
    Publishing date 2009-12-01T00:00:00Z
    Publisher Kowsar Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Two Consecutive Stillbirths with Multiple Intestinal Atresias in a 30-Year-Old Female

    Fatemeh Mahjoub / Maliheh Kadivar / Behnaz Moradi / Nargess Tabarzan

    Iranian Journal of Pediatrics, Vol 19, Iss 4, Pp 435-

    2009  Volume 438

    Abstract: Background:Multiple duodenal and jejuno-ileal atresias are extremely uncommon. The familial occurrence of multiple intestinal atresias is even more unusual. Also fetal death with isolated intestinal atresia is very rare, and the combination of recurrent ... ...

    Abstract Background:Multiple duodenal and jejuno-ileal atresias are extremely uncommon. The familial occurrence of multiple intestinal atresias is even more unusual. Also fetal death with isolated intestinal atresia is very rare, and the combination of recurrent familial intestinal atresias and intra-uterine fetal death has not been reported previously. Case Presentation:We report on two cases of intra-uterine fetal death in a 30-year-old woman who is consanguineous with her husband and they have only one boy who carries chromosomal abnormality. To best of our knowledge this is the first reported case of two consecutive pregnancies with multiple intestinal atresias leading to intrauterine fetal death.Conclusion:Multiple and recurrent intestinal atresias are extremely uncommon. These rare cases may contribute to genetic mapping for intestinal atresias.
    Keywords Multiple Intestinal Atresias ; Repeated ; Consanguineous ; Marriage ; Intrauterine Fetal Death ; Familial ; Pediatrics ; RJ1-570 ; Medicine ; R ; DOAJ:Pediatrics ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Subject code 610
    Language English
    Publishing date 2009-12-01T00:00:00Z
    Publisher Tehran University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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