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  1. Article ; Online: The future of STI screening and treatment for youth: a National Survey of youth perspectives and intentions.

    Gogineni, Vinaya / Waselewski, Marika E / Jamison, Cornelius D / Bell, Jasmine A / Hadler, Nicole / Chaudhry, Kiren A / Chang, Tammy / Mmeje, Okeoma O

    BMC public health

    2021  Volume 21, Issue 1, Page(s) 2006

    Abstract: Background: Sexually transmitted infection (STI) rates continue to rise in the U.S., with disproportionately high rates among those aged 15-24 years. Effective programs and policies are necessary to address this growing public health problem. The ... ...

    Abstract Background: Sexually transmitted infection (STI) rates continue to rise in the U.S., with disproportionately high rates among those aged 15-24 years. Effective programs and policies are necessary to address this growing public health problem. The purpose of this study is to assess the perspectives of a national sample of youth on access to STI care and behaviors regarding STIs.
    Methods: MyVoice, a national text message survey of youth, was used to pose four open-ended questions on STI screening and treatment to 1115 youth aged 14-24 in August 2018. A mixed-methods strategy was employed for the study. Qualitative data was analyzed using a modified grounded theory approach. Summary statistics were calculated for demographic data and prevalence of themes.
    Results: Of the 800 participants who responded to at least one question (72% response rate), mean age was 19 years (SD = 3.1), 55% identified as female, 61% identified as non-Hispanic white, and 33% qualified for free/reduced lunch. A majority felt it would be easy to get screened (69%) or treated (68%) for an STI. Nearly all respondents (95%) stated they would share an STI diagnosis with their sexual partners.
    Conclusions: Despite high rates of STIs among youth, most respondents reported that STI screening and treatment is accessible, and they would share an STI diagnosis with their partner.
    MeSH term(s) Adolescent ; Adult ; Female ; Humans ; Intention ; Mass Screening ; Sexual Behavior ; Sexual Partners ; Sexually Transmitted Diseases/diagnosis ; Sexually Transmitted Diseases/epidemiology ; Sexually Transmitted Diseases/therapy ; Text Messaging ; Young Adult
    Language English
    Publishing date 2021-11-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1471-2458
    ISSN (online) 1471-2458
    DOI 10.1186/s12889-021-12091-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Youth Knowledge and Perspectives on Expedited Partner Therapy.

    Jamison, Cornelius D / Waselewski, Marika / Gogineni, Vinaya / Bell, Jasmine / Hadler, Nicole / Chaudhry, Kiren / Chang, Tammy / Mmeje, Okeoma

    The Journal of adolescent health : official publication of the Society for Adolescent Medicine

    2021  Volume 70, Issue 1, Page(s) 114–119

    Abstract: Purpose: Expedited partner therapy (EPT) is an effective sexually transmitted infection (STI) treatment and prevention practice that allows clinicians to provide treatment to the sexual partner(s) of individuals diagnosed with chlamydia and/or gonorrhea ...

    Abstract Purpose: Expedited partner therapy (EPT) is an effective sexually transmitted infection (STI) treatment and prevention practice that allows clinicians to provide treatment to the sexual partner(s) of individuals diagnosed with chlamydia and/or gonorrhea infections without a clinical evaluation. Due to the high incidence of STIs among youth, we sought to understand youth awareness and beliefs about EPT use.
    Methods: MyVoice, a national text message survey of youth aged 14-24 years, posed 5 questions on EPT knowledge and perceptions to 1,115 youth in August 2018. Responses were reviewed to identify themes and iteratively develop a codebook. Two reviewers independently coded each question, and a third reviewer resolved discrepancies. Summary statistics were calculated for demographic and thematic analysis.
    Results: A total of 835 participants responded to at least 1 question (74.9% response rate). Majority of youth (91.9%, n = 730/794) felt that it would be important to help their partners get treatment if they tested positive for chlamydia or gonorrhea. Although most participants were unaware of EPT (86.4%, n = 657/760), 81.3% (n = 624/768) supported the policy stating that it is "pretty darn convenient." Youth also noted they would be interested in asking their provider for EPT. Participants opposing EPT (6.9%, n = 53/768) noted that "they [sexual partner] are responsible for their own health" and preferred to "tell my partner to go to [their] doctor."
    Conclusions: Most youth in the MyVoice cohort felt that EPT was a good way to get treatment for their partners, even though the majority were not aware that EPT was available as an STI treatment option.
    MeSH term(s) Adolescent ; Adult ; Chlamydia Infections/drug therapy ; Chlamydia Infections/epidemiology ; Chlamydia Infections/prevention & control ; Contact Tracing ; Gonorrhea/drug therapy ; Gonorrhea/epidemiology ; Gonorrhea/prevention & control ; Humans ; Sexual Partners ; Sexually Transmitted Diseases/diagnosis ; Young Adult
    Language English
    Publishing date 2021-08-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1063374-1
    ISSN 1879-1972 ; 1054-139X
    ISSN (online) 1879-1972
    ISSN 1054-139X
    DOI 10.1016/j.jadohealth.2021.06.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Using a multicultural and multilingual awareness-raising strategy to enhance enrollment of racially underrepresented minoritized communities - the

    Bell, Jasmine / Cook, Sarah / Edwards, Terri L / Rice, Todd W / Self, Wesley H / Wheeler, Allison / Rhoads, Jillian / Stewart, Thomas G / Pulley, Jill M / Benhoff, Katelyn / Harris, Paul A / Wilkins, Consuelo

    Journal of clinical and translational science

    2022  Volume 7, Issue 1, Page(s) e9

    Abstract: Racially and ethnically minoritized populations have been historically excluded and underrepresented in research. This paper will describe best practices in multicultural and multilingual awareness-raising strategies used by the Recruitment Innovation ... ...

    Abstract Racially and ethnically minoritized populations have been historically excluded and underrepresented in research. This paper will describe best practices in multicultural and multilingual awareness-raising strategies used by the Recruitment Innovation Center to increase minoritized enrollment into clinical trials. The Passive Immunity Trial for Our Nation will be used as a primary example to highlight real-world application of these methods to raise awareness, engage community partners, and recruit diverse study participants.
    Language English
    Publishing date 2022-12-07
    Publishing country England
    Document type Journal Article
    ISSN 2059-8661
    ISSN (online) 2059-8661
    DOI 10.1017/cts.2022.506
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Research Bronchoscopies in Critically Ill Research Participants: An Official American Thoracic Society Workshop Report.

    Mikacenic, Carmen / Fussner, Lynn A / Bell, Jasmine / Burnham, Ellen L / Chlan, Linda L / Cook, Sarah K / Dickson, Robert P / Almonor, Francis / Luo, Fengming / Madan, Karan / Morales-Nebreda, Luisa / Mould, Kara J / Simpson, A John / Singer, Benjamin D / Stapleton, Renee D / Wendt, Chris H / Files, D Clark

    Annals of the American Thoracic Society

    2022  Volume 20, Issue 5, Page(s) 621–631

    Abstract: Bronchoscopy for research purposes is a valuable tool to understand lung-specific biology in human participants. Despite published reports and active research protocols using this procedure in critically ill patients, no recent document encapsulates the ... ...

    Abstract Bronchoscopy for research purposes is a valuable tool to understand lung-specific biology in human participants. Despite published reports and active research protocols using this procedure in critically ill patients, no recent document encapsulates the important safety considerations and downstream applications of this procedure in this setting. The objectives were to identify safe practices for patient selection and protection of hospital staff, provide recommendations for sample procurement to standardize studies, and give guidance on sample preparation for novel research technologies. Seventeen international experts in the management of critically ill patients, bronchoscopy in clinical and research settings, and experience in patient-oriented clinical or translational research convened for a workshop. Review of relevant literature, expert presentations, and discussion generated the findings presented herein. The committee concludes that research bronchoscopy with bronchoalveolar lavage in critically ill patients on mechanical ventilation is valuable and safe in appropriately selected patients. This report includes recommendations on standardization of this procedure and prioritizes the reporting of sample management to produce more reproducible results between laboratories. This document serves as a resource to the community of researchers who endeavor to include bronchoscopy as part of their research protocols and highlights key considerations for the inclusion and safety of research participants.
    MeSH term(s) Humans ; Bronchoscopy ; Critical Illness ; Bronchoalveolar Lavage ; Dimercaprol ; Patient Selection
    Chemical Substances Dimercaprol (0CPP32S55X)
    Language English
    Publishing date 2022-05-24
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202302-106ST
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Decentralized clinical trials in the trial innovation network: Value, strategies, and lessons learned.

    Hanley, Daniel F / Bernard, Gordon R / Wilkins, Consuelo H / Selker, Harry P / Dwyer, Jamie P / Dean, J Michael / Benjamin, Daniel Kelly / Dunsmore, Sarah E / Waddy, Salina P / Wiley, Kenneth L / Palm, Marisha E / Mould, W Andrew / Ford, Daniel F / Burr, Jeri S / Huvane, Jacqueline / Lane, Karen / Poole, Lori / Edwards, Terri L / Kennedy, Nan /
    Boone, Leslie R / Bell, Jasmine / Serdoz, Emily / Byrne, Loretta M / Harris, Paul A

    Journal of clinical and translational science

    2023  Volume 7, Issue 1, Page(s) e170

    Abstract: New technologies and disruptions related to Coronavirus disease-2019 have led to expansion of decentralized approaches to clinical trials. Remote tools and methods hold promise for increasing trial efficiency and reducing burdens and barriers by ... ...

    Abstract New technologies and disruptions related to Coronavirus disease-2019 have led to expansion of decentralized approaches to clinical trials. Remote tools and methods hold promise for increasing trial efficiency and reducing burdens and barriers by facilitating participation outside of traditional clinical settings and taking studies directly to participants. The Trial Innovation Network, established in 2016 by the National Center for Advancing Clinical and Translational Science to address critical roadblocks in clinical research and accelerate the translational research process, has consulted on over 400 research study proposals to date. Its recommendations for decentralized approaches have included eConsent, participant-informed study design, remote intervention, study task reminders, social media recruitment, and return of results for participants. Some clinical trial elements have worked well when decentralized, while others, including remote recruitment and patient monitoring, need further refinement and assessment to determine their value. Partially decentralized, or "hybrid" trials, offer a first step to optimizing remote methods. Decentralized processes demonstrate potential to improve urban-rural diversity, but their impact on inclusion of racially and ethnically marginalized populations requires further study. To optimize inclusive participation in decentralized clinical trials, efforts must be made to build trust among marginalized communities, and to ensure access to remote technology.
    Language English
    Publishing date 2023-07-25
    Publishing country England
    Document type Journal Article
    ISSN 2059-8661
    ISSN (online) 2059-8661
    DOI 10.1017/cts.2023.597
    Database MEDical Literature Analysis and Retrieval System OnLINE

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