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  1. Book ; Online: Embeddedness of liquid-vapour interfaces in stable equilibrium

    Bellettini, Costante

    2021  

    Abstract: We consider a classical (capillary) model for a one-phase liquid in equilibrium. The liquid (e.g. water) is subject to a volume constraint, it does not mix with the surrounding vapour (e.g. air), it may come into contact with solid supports (e.g. a ... ...

    Abstract We consider a classical (capillary) model for a one-phase liquid in equilibrium. The liquid (e.g. water) is subject to a volume constraint, it does not mix with the surrounding vapour (e.g. air), it may come into contact with solid supports (e.g. a container), and is subject to the action of an analytic potential field (e.g. gravity). The region occupied by the liquid is described as a set of locally finite perimeter (Caccioppoli set) in $\mathbb{R}^3$; no a priori regularity assumption is made on its boundary. The (twofold) scope in this note is to propose a weakest possible set of mathematical assumptions that sensibly describe a condition of stable equilibrium for the liquid-vapour interface (the capillary surface), and to infer from those that this interface is a smoothly embedded analytic surface. (The liquid-solid-vapour junction, or free boundary, can be present but is not analysed here.) The result relies fundamentally on the recent varifold regularity theory developed by Wickramasekera and the author, and on the identification of a suitable formulation of the stability condition.

    Comment: 32 pages, 3 Figures
    Keywords Mathematics - Analysis of PDEs ; Mathematical Physics ; Mathematics - Differential Geometry ; 49Q20 ; 49Q10 ; 35J62 ; 53A10
    Subject code 621
    Publishing date 2021-04-25
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: Antithrombotic Therapy in Patients with Coronary Artery Disease and Prior Stroke.

    Bellettini, Elisa / De Luca, Leonardo

    Journal of clinical medicine

    2021  Volume 10, Issue 9

    Abstract: Patients with coronary artery disease (CAD) and prior cerebrovascular events (CVE) are frequently faced in clinical practice and present a high rate of both ischemic and bleeding events. For these reasons, the antithrombotic management is particularly ... ...

    Abstract Patients with coronary artery disease (CAD) and prior cerebrovascular events (CVE) are frequently faced in clinical practice and present a high rate of both ischemic and bleeding events. For these reasons, the antithrombotic management is particularly challenging in this subgroup of patients. Recent trials suggest that, although a potent antiplatelet strategy is safe in the acute phases of myocardial ischemia for these patients, the risk of major bleeding complications, including intracranial hemorrhage, is extremely high when the antithrombotic therapy is prolonged for a long period of time. Therefore, especially in patients with chronic CAD and history of CVE, the antithrombotic management should be carefully balanced between ischemic and bleeding risks. The present review is aimed at critically evaluating the available evidence to help make these crucial clinical decisions regarding the better antithrombotic therapy to use in this high-risk subgroup of patients.
    Language English
    Publishing date 2021-04-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm10091923
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Antithrombotic Therapy in Patients with Coronary Artery Disease and Prior Stroke

    Elisa Bellettini / Leonardo De Luca

    Journal of Clinical Medicine, Vol 10, Iss 1923, p

    2021  Volume 1923

    Abstract: Patients with coronary artery disease (CAD) and prior cerebrovascular events (CVE) are frequently faced in clinical practice and present a high rate of both ischemic and bleeding events. For these reasons, the antithrombotic management is particularly ... ...

    Abstract Patients with coronary artery disease (CAD) and prior cerebrovascular events (CVE) are frequently faced in clinical practice and present a high rate of both ischemic and bleeding events. For these reasons, the antithrombotic management is particularly challenging in this subgroup of patients. Recent trials suggest that, although a potent antiplatelet strategy is safe in the acute phases of myocardial ischemia for these patients, the risk of major bleeding complications, including intracranial hemorrhage, is extremely high when the antithrombotic therapy is prolonged for a long period of time. Therefore, especially in patients with chronic CAD and history of CVE, the antithrombotic management should be carefully balanced between ischemic and bleeding risks. The present review is aimed at critically evaluating the available evidence to help make these crucial clinical decisions regarding the better antithrombotic therapy to use in this high-risk subgroup of patients.
    Keywords antithrombotic therapy ; clopidogrel ; ticagrelor ; prasugrel ; aspirin ; rivaroxaban ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
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  4. Article ; Online: Balancing gene transfection and cytotoxicity of nucleic acid carriers with focus on ocular and hepatic disorders: evaluation of hydrophobic and hydrophilic polyethyleneimine derivatives.

    de Oliveira, Fernando A / Albuquerque, Lindomar J C / Nascimento-Sales, Michelle / Christoffolete, Marcelo A / Bellettini, Ismael C / Giacomelli, Fernando C

    Journal of materials chemistry. B

    2023  Volume 11, Issue 20, Page(s) 4556–4571

    Abstract: Polyethyleneimine (PEI) derivatives substituted by lactose, succinic acid or alkyl domains were evaluated as nonviral gene delivery vectors towards balancing gene transfection and cytotoxicity. The investigations were focused on pDNA transfection into ... ...

    Abstract Polyethyleneimine (PEI) derivatives substituted by lactose, succinic acid or alkyl domains were evaluated as nonviral gene delivery vectors towards balancing gene transfection and cytotoxicity. The investigations were focused on pDNA transfection into arising retinal pigment epithelia (ARPE-19) and human hepatocellular carcinoma (HepG2) cell lines. The first mentioned cell line was chosen as motivated by the non-negligible number of ocular disorders linked to gene aberrations, whereas the second one is a cell line overexpressing the asialoglycoprotein receptor (ASGP-R), which can bind to galactose residues. The presence of short alkyl domains (C
    MeSH term(s) Humans ; Polyethyleneimine/chemistry ; Plasmids ; Nucleic Acids ; Succinic Acid ; Lactose ; Transfection ; DNA/genetics ; DNA/chemistry ; Liver Neoplasms/genetics
    Chemical Substances Polyethyleneimine (9002-98-6) ; Nucleic Acids ; Succinic Acid (AB6MNQ6J6L) ; Lactose (J2B2A4N98G) ; DNA (9007-49-2)
    Language English
    Publishing date 2023-05-24
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2702241-9
    ISSN 2050-7518 ; 2050-750X
    ISSN (online) 2050-7518
    ISSN 2050-750X
    DOI 10.1039/d3tb00477e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Polyethylenimine as a Versatile Simultaneous Reducing and Stabilizing Agent Enabling One-Pot Synthesis of Transition-Metal Nanoparticles: Fundamental Aspects and Practical Implications.

    Ribeiro, Caroline A S / Panico, Karine / Handajevsky, Tamara J / da Silva, Fernanda Dias / Bellettini, Ismael C / Pavlova, Ewa / Giacomelli, Fernando C

    Langmuir : the ACS journal of surfaces and colloids

    2023  Volume 39, Issue 48, Page(s) 17353–17365

    Abstract: The large surface area of metallic nanoparticles provides them with particular optical, chemical, and biological properties, accordingly enabling their use in a wide array of applications. In this regard, facile and fast synthetic approaches are ... ...

    Abstract The large surface area of metallic nanoparticles provides them with particular optical, chemical, and biological properties, accordingly enabling their use in a wide array of applications. In this regard, facile and fast synthetic approaches are desirable for ready-to-use functional materials. Following early investigations focused on the direct synthesis of polymer-coated gold nanoparticles, we herein demonstrate that such a strategy can be used to manufacture different types of d-block transition-metal nanoparticles via a one-pot method in aqueous media and mild temperature conditions. Gold (Au
    Language English
    Publishing date 2023-11-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.3c02538
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: An analysis of urban population structure and dynamics through the automated management of the registry office

    Athos Bellettini

    Statistica, Vol 71, Iss 1, Pp 3-

    2013  Volume 8

    Keywords Probabilities. Mathematical statistics ; QA273-280 ; Mathematics ; QA1-939 ; Science ; Q
    Language English
    Publishing date 2013-05-01T00:00:00Z
    Publisher University of Bologna
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Book ; Online: Lecture Notes on Mean Curvature Flow, Barriers and Singular Perturbations

    Bellettini, Giovanni

    (Publications of the Scuola Normale Superiore ; 12)

    2013  

    Abstract: The aim of the book is to study some aspects of geometric evolutions, such as mean curvature flow and anisotropic mean curvature flow of hypersurfaces. We analyze the origin of such flows and their geometric and variational nature. Some of the most ... ...

    Author's details by Giovanni Bellettini
    Series title Publications of the Scuola Normale Superiore ; 12
    Abstract The aim of the book is to study some aspects of geometric evolutions, such as mean curvature flow and anisotropic mean curvature flow of hypersurfaces. We analyze the origin of such flows and their geometric and variational nature. Some of the most important aspects of mean curvature flow are described, such as the comparison principle and its use in the definition of suitable weak solutions. The anisotropic evolutions, which can be considered as a generalization of mean curvature flow, are studied from the view point of Finsler geometry. Concerning singular perturbations, we discuss the convergence of the Allen-Cahn (or Ginsburg-Landau) type equations to (possibly anisotropic) mean curvature flow before the onset of singularities in the limit problem. We study such kinds of asymptotic problems also in the static case, showing convergence to prescribed curvature-type problems
    Keywords Geometry ; Mathematics
    Language English
    Size Online-Ressource (Approx. 350 p), online resource
    Publisher Scuola Normale Superiore
    Publishing place Pisa ;s.l
    Document type Book ; Online
    ISBN 9788876424281 ; 9788876424298 ; 8876424288 ; 8876424296
    DOI 10.1007/978-88-7642-429-8
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  8. Article ; Online: Reduced cytotoxicity of nanomaterials driven by nano-bio interactions: Case study of single protein coronas enveloping polymersomes.

    de Oliveira, Fernando A / Albuquerque, Lindomar J C / Castro, Carlos E / Riske, Karin A / Bellettini, Ismael C / Giacomelli, Fernando C

    Colloids and surfaces. B, Biointerfaces

    2022  Volume 213, Page(s) 112387

    Abstract: The protein adsorption onto poly(acrylic acid)-block-polystyrene ( ... ...

    Abstract The protein adsorption onto poly(acrylic acid)-block-polystyrene (PAA
    MeSH term(s) Adsorption ; Nanoparticles/chemistry ; Nanostructures ; Protein Corona/chemistry ; Serum Albumin, Bovine/chemistry
    Chemical Substances Protein Corona ; Serum Albumin, Bovine (27432CM55Q)
    Language English
    Publishing date 2022-02-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1500523-9
    ISSN 1873-4367 ; 0927-7765
    ISSN (online) 1873-4367
    ISSN 0927-7765
    DOI 10.1016/j.colsurfb.2022.112387
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Cardiac imaging for the prediction of sudden cardiac arrest in patients with heart failure.

    De Lio, Francesca / Andreis, Alessandro / De Lio, Giulia / Bellettini, Matteo / Pidello, Stefano / Raineri, Claudia / Gallone, Guglielmo / Alunni, Gianluca / Frea, Simone / Imazio, Massimo / Castagno, Davide / De Ferrari, Gaetano Maria

    Heliyon

    2023  Volume 9, Issue 7, Page(s) e17710

    Abstract: The identification of heart failure (HF) patients at risk for arrhythmic sudden cardiac arrest (SCA) is a major challenge in the cardiovascular field. In addition to optimal medical treatment for HF, implantable cardioverter defibrillator (ICD) is ... ...

    Abstract The identification of heart failure (HF) patients at risk for arrhythmic sudden cardiac arrest (SCA) is a major challenge in the cardiovascular field. In addition to optimal medical treatment for HF, implantable cardioverter defibrillator (ICD) is currently recommended to prevent SCA in patients with reduced left ventricular ejection fraction (LVEF). The indication for an ICD implantation, in addition to HF etiology, New York Health Association (NYHA) class and life expectancy, mainly depends on LVEF value at echocardiography. However, the actual role of LVEF in the prediction of SCA has recently been debated, while newer multimodality imaging techniques with increased prognostic accuracy have been developed. Speckle tracking imaging allows the quantification of mechanical dispersion, a marker of electrophysiological heterogeneity predisposing to malignant arrhythmias, while advanced cardiac magnetic resonance techniques such as myocardial T1-mapping and extracellular volume fraction assessment allow the evaluation of interstitial diffuse fibrosis. Nuclear imaging is helpful for the appraisal of sympathetic nervous system dysfunction, while newer computed tomography techniques assessing myocardial delayed enhancement allow the identification of focal myocardial scar. This review will focus on the most modern advances in the field of cardiovascular imaging along with its applications for the prediction of SCA in patients with HF. Modern artificial intelligence applications in cardiovascular imaging will also be discussed.
    Language English
    Publishing date 2023-06-28
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e17710
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Electrospun blends comprised of poly(methyl methacrylate) and ethyl(hydroxyethyl)cellulose functionalized with perichromic dyes.

    Dreyer, Juliana P / Stock, Rafaela I / Nandi, Leandro G / Bellettini, Ismael C / Machado, Vanderlei G

    Carbohydrate polymers

    2020  Volume 236, Page(s) 115991

    Abstract: Ethyl(hydroxyethyl)cellulose (EHEC) was modified with 4-(2- (pyridin-4-yl)vinyl) phenol (PBM) and 4- [4-(dimethylamino)styryl]pyridine (DMASP), which are precursors of two well-known perichromic/fluorescent dyes, Brooker's merocyanine (BM) and 4- [4-( ... ...

    Abstract Ethyl(hydroxyethyl)cellulose (EHEC) was modified with 4-(2- (pyridin-4-yl)vinyl) phenol (PBM) and 4- [4-(dimethylamino)styryl]pyridine (DMASP), which are precursors of two well-known perichromic/fluorescent dyes, Brooker's merocyanine (BM) and 4- [4-(dimethylamino)styryl]-1-methypyridinium iodide (DSMI). The EHECs were mixed with poly(methyl methacrylate) (PMMA) to allow electrospinning and the nanofibers obtained were characterized by scanning electron microscopy, fluorescence microscopy, ATR-FTIR spectroscopy, thermogravimetry analysis, differential scanning calorimetry and fluorescence spectrophotometry and the absolute quantum yield and contact angle were determined. The PMMA/EHEC blends formed hydrophilic nanofibers, with high water absorption, in contrast to the pure PMMA nanofibers. PMMA/EHEC-PBM nanofibers exhibited cyan emission when excited in the UV region and PMMA/EHEC-DMASP showed intense green emission under excitation with laser in the blue region. Electrospinning of PMMA/modified EHEC in the proportion of 5:2 (wt/wt) provided nanochain-like nanofibers, which were verified by confocal microscopy. The potential for the use of the electrospun PMMA/EHEC-PBM nanofibers in the detection of CN
    Language English
    Publishing date 2020-02-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1501516-6
    ISSN 1879-1344 ; 0144-8617
    ISSN (online) 1879-1344
    ISSN 0144-8617
    DOI 10.1016/j.carbpol.2020.115991
    Database MEDical Literature Analysis and Retrieval System OnLINE

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