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  1. Article ; Online: ICD early after myocardial infarction: it is really necessary to wait 40 days before implantation?

    Bellicini, Maria Giulia / Cersosimo, Angelica / Cerini, Manuel / Bontempi, Luca / Curnis, Antonio / Arabia, Gianmarco

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

    2023  Volume 67, Issue 3, Page(s) 439–441

    Abstract: ESC Guidelines don't recommend ICD implantation within 40 days after MI, on the basis of old evidence with several limitations. However, a significant number of patients remain at high risk of arrhythmic death also in the early period after ACS, in these ...

    Abstract ESC Guidelines don't recommend ICD implantation within 40 days after MI, on the basis of old evidence with several limitations. However, a significant number of patients remain at high risk of arrhythmic death also in the early period after ACS, in these patients early ICD implantation or LifeVest may be use with benefit on survival.
    MeSH term(s) Humans ; Myocardial Infarction/therapy ; Time Factors ; Defibrillators, Implantable ; Death, Sudden, Cardiac/prevention & control
    Language English
    Publishing date 2023-12-15
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 1329179-8
    ISSN 1572-8595 ; 1383-875X
    ISSN (online) 1572-8595
    ISSN 1383-875X
    DOI 10.1007/s10840-023-01711-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Ion channel dysfunction and fibrosis in atrial fibrillation: Two sides of the same coin.

    Arabia, Gianmarco / Bellicini, Maria Giulia / Cersosimo, Angelica / Memo, Maurizio / Mazzarotto, Francesco / Inciardi, Riccardo Maria / Cerini, Manuel / Chen, Lin Yee / Aboelhassan, Mohamed / Benzoni, Patrizia / Mitacchione, Gianfranco / Bontempi, Luca / Curnis, Antonio

    Pacing and clinical electrophysiology : PACE

    2024  Volume 47, Issue 3, Page(s) 417–428

    Abstract: Background: Atrial fibrillation (AF) is a common heart rhythm disorder that is associated with an increased risk of stroke and heart failure (HF). Initially, an association between AF and ion channel dysfunction was identified, classifying the pathology ...

    Abstract Background: Atrial fibrillation (AF) is a common heart rhythm disorder that is associated with an increased risk of stroke and heart failure (HF). Initially, an association between AF and ion channel dysfunction was identified, classifying the pathology as a predominantly electrical disease. More recently it has been recognized that fibrosis and structural atrial remodeling play a driving role in the development of this arrhythmia also in these cases.
    Purpose: Understanding the role of fibrosis in genetic determined AF could be important to better comprise the pathophysiology of this arrhythmia and to refine its management also in nongenetic forms. In this review we analyze genetic and epigenetic mechanisms responsible for AF and their link with atrial fibrosis, then we will consider analogies with the pathophysiological mechanism in nongenetic AF, and discuss consequent therapeutic options.
    MeSH term(s) Humans ; Atrial Fibrillation/complications ; Heart Atria ; Fibrosis ; Ion Channels/genetics ; Ion Channels/therapeutic use ; Heart Failure
    Chemical Substances Ion Channels
    Language English
    Publishing date 2024-02-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 424437-0
    ISSN 1540-8159 ; 0147-8389
    ISSN (online) 1540-8159
    ISSN 0147-8389
    DOI 10.1111/pace.14944
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Telemedicine for the treatment of heart failure: new opportunities after COVID-19.

    Bellicini, Maria Giulia / D'Altilia, Francesca Pia / Gussago, Cristina / Adamo, Marianna / Lombardi, Carlo Mario / Tomasoni, Daniela / Inciardi, Riccardo Maria / Metra, Marco / Pagnesi, Matteo

    Journal of cardiovascular medicine (Hagerstown, Md.)

    2023  Volume 24, Issue 10, Page(s) 700–707

    Abstract: Abstract: During the Coronavirus Disease 2019 (COVID-19) pandemic, the epidemiology of heart failure significantly changed with reduced access to health system resources and a worsening of patients' outcome. Understanding the causes of these phenomena ... ...

    Abstract Abstract: During the Coronavirus Disease 2019 (COVID-19) pandemic, the epidemiology of heart failure significantly changed with reduced access to health system resources and a worsening of patients' outcome. Understanding the causes of these phenomena could be important to refine the management of heart failure during and after the pandemic. Telemedicine was associated with an improvement in heart failure outcomes in several studies; therefore, it may help in refining the out-of-hospital care of heart failure. In this review, the authors describe the changes in heart failure epidemiology during the COVID-19 pandemic; analyse available evidence on use and benefit of telemedicine during the pandemic and prepandemic periods; and discuss approaches to optimize the home-based or outpatient heart failure management in the future, beyond the pandemic.
    MeSH term(s) Humans ; COVID-19 ; SARS-CoV-2 ; Pandemics ; Telemedicine ; Heart Failure/diagnosis ; Heart Failure/epidemiology ; Heart Failure/therapy
    Language English
    Publishing date 2023-06-26
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 2223461-5
    ISSN 1558-2035 ; 1558-2027
    ISSN (online) 1558-2035
    ISSN 1558-2027
    DOI 10.2459/JCM.0000000000001514
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Left ventricular wall thickness and severity of cardiac disease in women and men with transthyretin amyloidosis.

    Aimo, Alberto / Tomasoni, Daniela / Porcari, Aldostefano / Vergaro, Giuseppe / Castiglione, Vincenzo / Passino, Claudio / Adamo, Marianna / Bellicini, Maria Giulia / Lombardi, Carlo Mario / Nardi, Matilde / Palamara, Gloria / Varrà, Guerino Giuseppe / Saro, Riccardo / Allegro, Valentina / Merlo, Marco / Sinagra, Gianfranco / Metra, Marco / Emdin, Michele / Rapezzi, Claudio

    European journal of heart failure

    2023  Volume 25, Issue 4, Page(s) 510–514

    Abstract: Aims: Cardiac amyloidosis (CA) is due to a deposition of amyloid fibrils in the heart causing an increase in wall thickness. A left ventricular (LV) wall thickness ≥12 mm plus at least one red flag should raise the suspicion of CA. As normal values of ... ...

    Abstract Aims: Cardiac amyloidosis (CA) is due to a deposition of amyloid fibrils in the heart causing an increase in wall thickness. A left ventricular (LV) wall thickness ≥12 mm plus at least one red flag should raise the suspicion of CA. As normal values of LV wall thickness are lower in women, the adoption or the same cut-off values for men and women could lead to underdiagnosis or delayed diagnosis in women. We investigated the relationship between LV wall thickness and the severity of cardiac involvement in women and men with transthyretin (ATTR) CA.
    Methods and results: We evaluated 330 consecutive patients diagnosed with ATTR-CA at three centres (Pisa, n = 232; Brescia, n = 69; Trieste, n = 29). Interventricular septum (IVS) and posterior wall (PW) thickness values were lower in women (n = 53, 16%) than men, but most differences were abolished when indexing by body surface area (BSA), height, or height
    Conclusions: Indexed LV wall thickness values, particularly by height
    MeSH term(s) Female ; Humans ; Male ; Amyloid Neuropathies, Familial/complications ; Amyloid Neuropathies, Familial/diagnostic imaging ; Heart Diseases/diagnostic imaging ; Heart Ventricles/pathology
    Language English
    Publishing date 2023-03-15
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1483672-5
    ISSN 1879-0844 ; 1388-9842
    ISSN (online) 1879-0844
    ISSN 1388-9842
    DOI 10.1002/ejhf.2824
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Value of the HFA-PEFF and H

    Tomasoni, Daniela / Aimo, Alberto / Merlo, Marco / Nardi, Matilde / Adamo, Marianna / Bellicini, Maria Giulia / Cani, Dario / Franzini, Maria / Khalil, Anas / Pancaldi, Edoardo / Panichella, Giorgia / Porcari, Aldostefano / Rossi, Maddalena / Vergaro, Giuseppe / Lombardi, Carlo Mario / Sinagra, Gianfranco / Rapezzi, Claudio / Emdin, Michele / Metra, Marco

    European journal of heart failure

    2022  Volume 24, Issue 12, Page(s) 2374–2386

    Abstract: Aims: The HFA-PEFF and H: Methods and results: We evaluated the diagnostic and prognostic value of the HFA-PEFF and H: Conclusions: The HFA-PEFF score has a higher diagnostic utility in HFpEF caused by CA and holds independent prognostic value for ...

    Abstract Aims: The HFA-PEFF and H
    Methods and results: We evaluated the diagnostic and prognostic value of the HFA-PEFF and H
    Conclusions: The HFA-PEFF score has a higher diagnostic utility in HFpEF caused by CA and holds independent prognostic value for all-cause mortality, while the H
    MeSH term(s) Humans ; Heart Failure/diagnosis ; Heart Failure/etiology ; Stroke Volume ; Ventricular Function, Left ; Prognosis ; Amyloidosis/complications ; Amyloidosis/diagnosis
    Language English
    Publishing date 2022-08-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 1483672-5
    ISSN 1879-0844 ; 1388-9842
    ISSN (online) 1879-0844
    ISSN 1388-9842
    DOI 10.1002/ejhf.2616
    Database MEDical Literature Analysis and Retrieval System OnLINE

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