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Article ; Online: Drinking Water Quality Assessment Using a Fuzzy Inference System Method: A Case Study of Rome (Italy).

Barzegar, Yas / Gorelova, Irina / Bellini, Francesco / D'Ascenzo, Fabrizio

International journal of environmental research and public health

2023 Volume 20, Issue 15

Abstract: Drinking water quality assessment is a major issue today, as it is crucial to supply safe drinking water to ensure the well-being of society. Predicting drinking water quality helps strengthen water management and fight water pollution; technologies and ... ...

Abstract	Drinking water quality assessment is a major issue today, as it is crucial to supply safe drinking water to ensure the well-being of society. Predicting drinking water quality helps strengthen water management and fight water pollution; technologies and practices for drinking water quality assessment are continuously improving; artificial intelligence methods prove their efficiency in this domain. This research effort seeks a hierarchical fuzzy model for predicting drinking water quality in Rome (Italy). The Mamdani fuzzy inference system is applied with different defuzzification methods. The proposed model includes three fuzzy intermediate models and one fuzzy final model. Each model consists of three input parameters and 27 fuzzy rules. A water quality assessment model is developed with a dataset that considers nine parameters (alkalinity, hardness, pH, Ca, Mg, fluoride, sulphate, nitrates, and iron). These nine parameters of drinking water are anticipated to be within the acceptable limits set to protect human health. Fuzzy-logic-based methods have been demonstrated to be appropriate to address uncertainty and subjectivity in drinking water quality assessment; they are an effective method for managing complicated, uncertain water systems and predicting drinking water quality. The proposed method can provide an effective solution for complex systems; this method can be modified easily to improve performance.
MeSH term(s)	Humans ; Water Quality ; Drinking Water ; Artificial Intelligence ; Rome ; Fuzzy Logic ; Italy
Chemical Substances	Drinking Water
Language	English
Publishing date	2023-08-04
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph20156522
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Conference proceedings: AIR FILLED GASTRIC ENDOSCOPIC BALLON FOR OBESITY; OUR RESULTS

Bonfante, F.P. / Zagni, I. / Anni, G. / Rossoni, G. / Bellini, F.

Endoscopy

2022 Volume 54, Issue S 01

Event/congress	ESGE Days 2022, Prague, Czech Republic, 2022-04-28
Language	English
Publishing date	2022-04-01
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	80120-3
ISSN	1438-8812 ; 0013-726X
ISSN (online)	1438-8812
ISSN	0013-726X
DOI	10.1055/s-0042-1745343
Database	Thieme publisher's database

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Article: Description of Twenty-Nine Animal Hoarding Cases in Italy: The Impact on Animal Welfare.

Sacchettino, Luigi / Gatta, Claudia / Giuliano, Viviana Orsola / Bellini, Francesca / Liverini, Alessia / Ciani, Francesca / Avallone, Luigi / d'Angelo, Danila / Napolitano, Francesco

Animals : an open access journal from MDPI

2023 Volume 13, Issue 18

Abstract: The hoarding of animals is a psychiatric disease, characterized by a compulsive collection of animals, with a relevant impact upon the care and welfare of animals, as well as on human society. In Italy, there are neither substantial reports nor ... ...

Abstract	The hoarding of animals is a psychiatric disease, characterized by a compulsive collection of animals, with a relevant impact upon the care and welfare of animals, as well as on human society. In Italy, there are neither substantial reports nor information shared about such a phenomenon, making it difficult to draw a clear picture of the hoarder profile. Therefore, in the present work, we sought to detail 29 cases of animal accumulators in Italy, who lived within two areas of the Lazio region, and accumulated a total of 1080 animals from 2019 to 2022. In line with other international studies, we observed a prevalence of middle-aged (in their fifties) women, who lived mainly alone in a high level of social and health degradation. Most of the hoarded animals exhibited severe signs of dehydration and malnutrition, muscle hypotrophy, dermatological injuries, and behavioral disorders. Animal hoarding is not yet fully understood nor recognized as a psychosocial disorder, although it produces a deep suffering for the hoarder themselves, as well as corresponding family members, and the animals accumulated. Therefore, given the crucial impact of animal hoarding upon human and animal welfare, cross-cultural networks aimed at properly raising awareness of the problem could be established.
Language	English
Publishing date	2023-09-20
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani13182968
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Article: Risk management with expectiles

Bellini, Fabio / Di Bernardino, Elena

The European journal of finance Vol. 23, No. 4/6 , p. 487-506

2017 Volume 23, Issue 4, Page(s) 487–506

Author's details	Fabio Bellini and Elena Di Bernardino
Keywords	Risikomaß ; Prognoseverfahren ; Portfolio-Management
Language	English
Dates of publication	2017-9999
Publisher	Routledge, Taylor & Francis Group
Publishing place	Abingdon, Oxon
Document type	Article
ZDB-ID	1282412-4 ; 2001610-4
ISSN	1466-4364 ; 1351-847X
ISSN (online)	1466-4364
ISSN	1351-847X
Database	ECONomics Information System

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Article: Cow's milk allergy (CMA) in children: identification of allergologic tests predictive of food allergy.

Bellini, F / Ricci, G / Remondini, D / Pession, A

European annals of allergy and clinical immunology

2014 Volume 46, Issue 3, Page(s) 100–105

Abstract: Oral food challenge (OFC) is still considered the gold standard for diagnosis of food allergy (FA). Skin prick test (SPT) and specific IgE (sIgE) tests are very useful but limited in their predictive accuracy. End point test (EPT) has been recently ... ...

Abstract	Oral food challenge (OFC) is still considered the gold standard for diagnosis of food allergy (FA). Skin prick test (SPT) and specific IgE (sIgE) tests are very useful but limited in their predictive accuracy. End point test (EPT) has been recently considered to determine the starting dose to induce oral desensitization. Allergometric tests combined may discriminate children at higher risk of reactions during OFC. We considered 94 children referred to our Allergy and Immunology Pediatric Department between January 2009 and December 2011 with CMA. Cutaneous allergometric skin tests (SPT and EPT) were periodically performed on all 94 children with CMA; sIgE levels against cow's milk proteins (CMP) α-lactalbumin, β-lactoglobulin and casein were periodically evaluated through blood samples every 6-12 months. During the period of the study, 26/94 (27.6%) children underwent more than once OFC. We collected 135 OFC compared with clinical presentation: 49/135 (36.2%) OFC were performed shortly after the onset of symptoms directly related to spontaneous intake of milk, to confirm suspicion of FA; 86/135 (63.7%) OFC were performed to evaluate the acquisition of tolerance. Of these, 52/86 (60.4%) OFC resulted positive, 34/86 (39.5%) were negative. The 3D EPT has the best ratio sensitivity (SE) / positive predictive value (PPV), SE 83%, specificity (SP) 58.3%, PPV 89.3%, negative predictive value (NPV) 45.1%. EPT 6D and 7D have the best PPV (100%) with a low NPV (respectively 22.2% and 21.2%). We obtained that a mean fresh milk wheal diameter ≥ 12 mm was predictive of 97% OFC, but only 32/101 (31.6%) allergic children presented this value. The tests with a wheal diameter ≤ 5 were performed on younger children, all of which were less than 9 months old; only 5 other tests performed on less than 9 months olds resulted in the others subgroups (1 in ≥ 12 mm wheal and 4 in the group between 6-11 mm). We also found that 95% of children with 4D EPT wheal diameter < 6 mm resulted tolerant. This cut off could be useful to decide which children have a lower risk of reactions during the OFC. EPT is more useful than SPT especially for children < 1 year of age being a less operator dependent test, and it could be helpful to discriminate between children with the highest risk to develop anaphylaxis following an OFC (≥ 5D positive EPT) and children with lowest risk (> 2D positive EPT), but it can't replace OFC, that currently remains the gold standard in the diagnosis of FA. We also underline that in allergic children younger than 9 months old, the values of SPT with fresh milk is much lower than in older children, so that it's better to separate this group of age when we try to predict the evolution of OFC through the evaluation with EPT. A validation of such results in a prospective study could maybe be useful to confirm the outcome of our data in the predictivity of OFC.
MeSH term(s)	Age Factors ; Anaphylaxis/immunology ; Biomarkers/blood ; Caseins/immunology ; Dermatitis, Atopic/diagnosis ; Dermatitis, Atopic/immunology ; Endpoint Determination ; Humans ; Immunoglobulin E/blood ; Infant ; Intradermal Tests ; Lactalbumin/immunology ; Lactoglobulins/immunology ; Milk Hypersensitivity/blood ; Milk Hypersensitivity/diagnosis ; Milk Hypersensitivity/immunology ; Milk Proteins/immunology ; Predictive Value of Tests ; Risk Factors ; Severity of Illness Index ; Time Factors
Chemical Substances	Biomarkers ; Caseins ; Lactoglobulins ; Milk Proteins ; Immunoglobulin E (37341-29-0) ; Lactalbumin (9013-90-5)
Language	English
Publishing date	2014-05
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2105540-3
ISSN	1764-1489 ; 0397-9148
ISSN	1764-1489 ; 0397-9148
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Predictors and moderators of burden of care and emotional distress in first-episode psychosis caregivers: results from the GET UP pragmatic cluster randomised controlled trial.

Onwumere, J / Bonetto, C / Lasalvia, A / Miglietta, E / Veronese, A / Bellini, F / Imbesi, M / Bebbington, P / Kuipers, E / Ruggeri, M

Epidemiology and psychiatric sciences

2019 Volume 29, Page(s) e27

Abstract: Aims: First-episode psychosis (FEP) is a major life event and can have an adverse impact on the diagnosed individual and their families. The importance of intervening early and providing optimal treatments is widely acknowledged. In comparison to ... ...

Abstract	Aims: First-episode psychosis (FEP) is a major life event and can have an adverse impact on the diagnosed individual and their families. The importance of intervening early and providing optimal treatments is widely acknowledged. In comparison to patient groups, literature is scarce on identifying treatment predictors and moderators of caregiver outcomes. This study aimed to identify pre-treatment characteristics predicting and/or moderating carer outcomes, based on data from a multi-element psychosocial intervention to FEP patients and carers (GET-UP PIANO trial). Methods: Carer demography, type of family relationship, patient contact hours, pre-treatment carer burden, patient perceptions of parental caregiving and expressed emotion (EE) were selected, a priori, as potential predictors/moderators of carer burden and emotional distress at 9 months post treatment. Outcomes were analysed separately in mixed-effects random regression models. Results: Analyses were performed on 260 carers. Only patient perceptions of early maternal criticism predicted reports of lower carer burden at follow-up. However, multiple imputation analysis failed to confirm this result. For treatment moderators: higher levels of carer burden at baseline yielded greater reductions in carer emotional distress at follow-up in the experimental group compared with treatment as usual (TAU). Higher levels of perceived EE moderated greater reductions in carer reports of tension in experimental group, compared with TAU, at follow-up. In younger caregivers (<51 years old), there were greater reductions in levels of worry during the baseline to follow-up period, within the experimental group compared with TAU. Conclusion: The study failed to identify significant treatment predictors of FEP carer outcomes. However, our preliminary findings suggest that optimal treatment outcomes for carers at first episode might be moderated by younger carer age, and carers reporting higher baseline levels of burden, and where patients perceive higher levels of negative effect from caregivers.
MeSH term(s)	Caregivers/psychology ; Caregivers/statistics & numerical data ; Cluster Analysis ; Cost of Illness ; Expressed Emotion ; Female ; Humans ; Italy ; Male ; Middle Aged ; Psychological Distress ; Psychotic Disorders/psychology ; Psychotic Disorders/therapy
Language	English
Publishing date	2019-04-10
Publishing country	England
Document type	Journal Article ; Multicenter Study ; Randomized Controlled Trial
ZDB-ID	2607964-1
ISSN	2045-7979 ; 2045-7960
ISSN (online)	2045-7979
ISSN	2045-7960
DOI	10.1017/S2045796019000155
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Article ; Online: Stopping Feline Coronavirus Shedding Prevented Feline Infectious Peritonitis.

Addie, Diane D / Bellini, Flora / Covell-Ritchie, Johanna / Crowe, Ben / Curran, Sheryl / Fosbery, Mark / Hills, Stuart / Johnson, Eric / Johnson, Carrie / Lloyd, Steven / Jarrett, Oswald

Viruses

2023 Volume 15, Issue 4

Abstract: After an incubation period of weeks to months, up to 14% of cats infected with feline coronavirus (FCoV) develop feline infectious peritonitis (FIP): a potentially lethal pyogranulomatous perivasculitis. The aim of this study was to find out if stopping ... ...

Abstract	After an incubation period of weeks to months, up to 14% of cats infected with feline coronavirus (FCoV) develop feline infectious peritonitis (FIP): a potentially lethal pyogranulomatous perivasculitis. The aim of this study was to find out if stopping FCoV faecal shedding with antivirals prevents FIP. Guardians of cats from which FCoV had been eliminated at least 6 months earlier were contacted to find out the outcome of their cats; 27 households were identified containing 147 cats. Thirteen cats were treated for FIP, 109 cats shed FCoV and 25 did not; a 4-7-day course of oral GS-441524 antiviral stopped faecal FCoV shedding. Follow-up was from 6 months to 3.5 years; 11 of 147 cats died, but none developed FIP. A previous field study of 820 FCoV-exposed cats was used as a retrospective control group; 37 of 820 cats developed FIP. The difference was statistically highly significant (
MeSH term(s)	Animals ; Cats ; Feline Infectious Peritonitis/drug therapy ; Feline Infectious Peritonitis/prevention & control ; Coronavirus, Feline ; Retrospective Studies ; Coronavirus Infections/drug therapy ; Coronavirus Infections/prevention & control ; Coronavirus Infections/veterinary ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use
Chemical Substances	Antiviral Agents
Language	English
Publishing date	2023-03-23
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2516098-9
ISSN	1999-4915 ; 1999-4915
ISSN (online)	1999-4915
ISSN	1999-4915
DOI	10.3390/v15040818
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Option pricing in a conditional Bilateral Gamma model

Bellini, Fabio / Mercuri, Lorenzo

Central European journal of operations research : CEJOR ; official journal of the Austrian, Croatian, Czech, Hungarian, Slovakian and Slovenian OR Societies Vol. 22, No. 2 , p. 373-390

2014 Volume 22, Issue 2, Page(s) 373–390

Author's details	Fabio Bellini; Lorenzo Mercuri
Keywords	Bilateral Gamma ; Garch ; Bilateral Esscher transform ; Semianalytical pricing ; SPX options
Language	English
Size	graph. Darst.
Publisher	Springer
Publishing place	Berlin ; Heidelberg
Document type	Article
ZDB-ID	1178875-6 ; 2093829-9
ISSN	1613-9178 ; 1435-246X
ISSN (online)	1613-9178
ISSN	1435-246X
Database	ECONomics Information System

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Article ; Online: A bilateral N2pc (N2pcb) component is elicited by search targets displayed on the vertical midline.

Doro, Mattia / Bellini, Francesco / Brigadoi, Sabrina / Eimer, Martin / Dell'Acqua, Roberto

Psychophysiology

2019 Volume 57, Issue 3, Page(s) e13512

Abstract: The study of visually elicited event-related potentials (ERPs) detected at posterior recording sites during visual search has enormously advanced our knowledge about how and when visuo-spatial attention locks onto one or more laterally presented target ... ...

Abstract	The study of visually elicited event-related potentials (ERPs) detected at posterior recording sites during visual search has enormously advanced our knowledge about how and when visuo-spatial attention locks onto one or more laterally presented target objects. The N2pc component to lateral targets has been pivotal to further our understanding of the mechanisms and time course of target selection in visual search. However, the N2pc cannot track visuo-spatial attention deployment to targets displayed along the vertical midline. Here, we introduce a new ERP marker (N2pcb component) that is elicited during the selection of such midline targets. In line with retinal and callosal projections from striate to ventral extrastriate cortex, this component reflects an enhanced negativity elicited by midline targets over both posterior hemispheres. By comparing the attentional selection of lateral and midline targets in a singleton search condition and a feature search condition, we show that the N2pcb is triggered at the same time as the N2pc to lateral targets, and shows the same onset latency difference between singleton and feature search. We conclude that the N2pcb and N2pc components reflect the same attentional target selection processes in visual search.
MeSH term(s)	Adult ; Attention/physiology ; Electroencephalography ; Evoked Potentials/physiology ; Evoked Potentials, Visual/physiology ; Female ; Humans ; Male ; Space Perception/physiology ; Visual Fields/physiology ; Visual Perception/physiology ; Young Adult
Language	English
Publishing date	2019-12-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	209486-1
ISSN	1540-5958 ; 0048-5772
ISSN (online)	1540-5958
ISSN	0048-5772
DOI	10.1111/psyp.13512
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Oral Mutian®X stopped faecal feline coronavirus shedding by naturally infected cats.

Addie, Diane D / Curran, Sheryl / Bellini, Flora / Crowe, Ben / Sheehan, Emily / Ukrainchuk, Lesya / Decaro, Nicola

Research in veterinary science

2020 Volume 130, Page(s) 222–229

Abstract: Feline coronavirus (FCoV) is common among cats living indoors in groups. In about 10% of infected cats, a potentially lethal disease, feline infectious peritonitis (FIP) occurs. Virus transmission is faecal-oral. Mutian® Xraphconn (Mutian X) is a product ...

Abstract	Feline coronavirus (FCoV) is common among cats living indoors in groups. In about 10% of infected cats, a potentially lethal disease, feline infectious peritonitis (FIP) occurs. Virus transmission is faecal-oral. Mutian® Xraphconn (Mutian X) is a product marketed to treat cats with FIP but is also being used to stop virus shedding, although no clear guidelines exist for its use for this purpose. The aim of this study was to establish the minimum dose and treatment duration required to ensure viral clearance from the faeces of asymptomatic virus-shedding cats. In five multicat households, 29 cats naturally infected with FCoV and actively shedding virus in the faeces were given Mutian X pills. Virus shedding was monitored using reverse-transcription quantitative polymerase chain reaction (RT-qPCR) controlled for faecal inhibitors to ensure sensitivity. Mutian X given orally cleared the virus in 29 cats; although four cats required a repeated course to finally stop virus shedding. A dose of 4 mg/kg q24 h for four days was found to be the optimal treatment protocol: 2 mg/kg cleared only 80% of cats. Post-treatment using a sensitive RT-qPCR test was essential to ensure that virus clearance had been achieved, since failure to clear even one cat can result in re-infection of the others. Records of virus shedding by cats before treatment provided a retrospective control: significantly more cats stopped shedding virus after Mutian X than recovered from infection during the control period (p < .00001). This is the first report of the successful elimination of faecal FCoV shedding in chronically infected cats.
MeSH term(s)	Administration, Oral ; Animals ; Antiviral Agents/therapeutic use ; Cats ; Coronavirus, Feline/drug effects ; Feces/virology ; Feline Infectious Peritonitis/drug therapy ; Retrospective Studies ; Virus Shedding/drug effects
Chemical Substances	Antiviral Agents
Keywords	covid19
Language	English
Publishing date	2020-02-19
Publishing country	England
Document type	Journal Article
ZDB-ID	840961-4
ISSN	1532-2661 ; 0034-5288
ISSN (online)	1532-2661
ISSN	0034-5288
DOI	10.1016/j.rvsc.2020.02.012
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