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  1. Article: Critical care escalation for treatment-refractory haematological malignancies.

    Benger, Matthew / Petsas, Anna

    British journal of hospital medicine (London, England : 2005)

    2019  Volume 80, Issue 4, Page(s) 238

    MeSH term(s) Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Clinical Decision-Making ; Critical Care ; Disease Progression ; Female ; Hematologic Neoplasms/therapy ; Humans ; Middle Aged ; Multiple Myeloma/complications ; Multiple Myeloma/drug therapy ; Palliative Care ; Pleural Effusion/etiology ; Pleural Effusion/therapy ; Treatment Failure
    Language English
    Publishing date 2019-04-25
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1750-8460
    ISSN 1750-8460
    DOI 10.12968/hmed.2019.80.4.238
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The critical distinction between characterisation and causation in studies of COVID-19-associated cerebrovascular pathology.

    Benger, Matthew / Williams, Owain / Siddiqui, Juveria / Sztriha, Laszlo

    Brain, behavior, and immunity

    2020  Volume 91, Page(s) 790–791

    MeSH term(s) COVID-19/complications ; COVID-19/physiopathology ; Cerebral Hemorrhage/etiology ; Cerebral Hemorrhage/physiopathology ; Cerebrovascular Disorders/etiology ; Humans ; Risk Factors ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-11-13
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 639219-2
    ISSN 1090-2139 ; 0889-1591
    ISSN (online) 1090-2139
    ISSN 0889-1591
    DOI 10.1016/j.bbi.2020.11.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Intracerebral haemorrhage and COVID-19: Clinical characteristics from a case series.

    Benger, Matthew / Williams, Owain / Siddiqui, Juveria / Sztriha, Laszlo

    Brain, behavior, and immunity

    2020  Volume 88, Page(s) 940–944

    MeSH term(s) Adult ; Anticoagulants/therapeutic use ; Basal Ganglia Hemorrhage/complications ; Basal Ganglia Hemorrhage/diagnostic imaging ; Basal Ganglia Hemorrhage/epidemiology ; Basal Ganglia Hemorrhage/physiopathology ; Betacoronavirus ; Brain/diagnostic imaging ; COVID-19 ; Cerebral Angiography ; Cerebral Hemorrhage/complications ; Cerebral Hemorrhage/diagnostic imaging ; Cerebral Hemorrhage/epidemiology ; Cerebral Hemorrhage/physiopathology ; Comorbidity ; Computed Tomography Angiography ; Coronavirus Infections/complications ; Coronavirus Infections/epidemiology ; Coronavirus Infections/physiopathology ; Diabetes Mellitus, Type 2/epidemiology ; Endothelium, Vascular/physiopathology ; Female ; Frontal Lobe/blood supply ; Heparin, Low-Molecular-Weight/therapeutic use ; Humans ; Hypertension/epidemiology ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Myocardial Ischemia/epidemiology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/physiopathology ; Pulmonary Embolism/drug therapy ; Pulmonary Embolism/epidemiology ; Retrospective Studies ; Risk Factors ; SARS-CoV-2 ; Severity of Illness Index ; Tomography, X-Ray Computed ; Venous Thrombosis/drug therapy ; Venous Thrombosis/epidemiology ; Warfarin/therapeutic use
    Chemical Substances Anticoagulants ; Heparin, Low-Molecular-Weight ; Warfarin (5Q7ZVV76EI)
    Keywords covid19
    Language English
    Publishing date 2020-06-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 639219-2
    ISSN 1090-2139 ; 0889-1591
    ISSN (online) 1090-2139
    ISSN 0889-1591
    DOI 10.1016/j.bbi.2020.06.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Autism spectrum disorder: prospects for treatment using gene therapy.

    Benger, Matthew / Kinali, Maria / Mazarakis, Nicholas D

    Molecular autism

    2018  Volume 9, Page(s) 39

    Abstract: Autism spectrum disorder (ASD) is characterised by the concomitant occurrence of impaired social interaction; restricted, perseverative and stereotypical behaviour; and abnormal communication skills. Recent epidemiological studies have reported a ... ...

    Abstract Autism spectrum disorder (ASD) is characterised by the concomitant occurrence of impaired social interaction; restricted, perseverative and stereotypical behaviour; and abnormal communication skills. Recent epidemiological studies have reported a dramatic increase in the prevalence of ASD with as many as 1 in every 59 children being diagnosed with ASD. The fact that ASD appears to be principally genetically driven, and may be reversible postnatally, has raised the exciting possibility of using gene therapy as a disease-modifying treatment. Such therapies have already started to seriously impact on human disease and particularly monogenic disorders (e.g. metachromatic leukodystrophy, SMA type 1). In regard to ASD, technical advances in both our capacity to model the disorder in animals and also our ability to deliver genes to the central nervous system (CNS) have led to the first preclinical studies in monogenic ASD, involving both gene replacement and silencing. Furthermore, our increasing awareness and understanding of common dysregulated pathways in ASD have broadened gene therapy's potential scope to include various polygenic ASDs. As this review highlights, despite a number of outstanding challenges, gene therapy has excellent potential to address cognitive dysfunction in ASD.
    MeSH term(s) Animals ; Autism Spectrum Disorder/genetics ; Autism Spectrum Disorder/therapy ; Genetic Therapy/methods
    Language English
    Publishing date 2018-06-20
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2540930-X
    ISSN 2040-2392 ; 2040-2392
    ISSN (online) 2040-2392
    ISSN 2040-2392
    DOI 10.1186/s13229-018-0222-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Comparing APLS and oranges: caution with the use of direct-acting oral anticoagulants (DOACs) instead of warfarin in the treatment of antiphospholipid syndrome (APLS).

    Benger, Matthew / Vink, Jasper / Snell, Luke Blagdon / Breen, Karen

    BMJ case reports

    2019  Volume 12, Issue 4

    Abstract: A 63-year-old woman with known antiphospholipid syndrome (APLS) presented with catastrophic APLS and multiorgan dysfunction after a change in her anticoagulation from warfarin to rivaroxaban. Evidence suggests direct-acting oral anticoagulants (DOACs) ... ...

    Abstract A 63-year-old woman with known antiphospholipid syndrome (APLS) presented with catastrophic APLS and multiorgan dysfunction after a change in her anticoagulation from warfarin to rivaroxaban. Evidence suggests direct-acting oral anticoagulants (DOACs) like rivaroxaban may be less effective than warfarin in secondary prevention of thrombotic events in high-risk APLS patients.
    MeSH term(s) Administration, Oral ; Anticoagulants/therapeutic use ; Antiphospholipid Syndrome/complications ; Antiphospholipid Syndrome/drug therapy ; Factor Xa Inhibitors/administration & dosage ; Factor Xa Inhibitors/adverse effects ; Female ; Humans ; Middle Aged ; Rivaroxaban/administration & dosage ; Rivaroxaban/adverse effects ; Secondary Prevention ; Thrombosis/etiology ; Thrombosis/prevention & control ; Warfarin/therapeutic use
    Chemical Substances Anticoagulants ; Factor Xa Inhibitors ; Warfarin (5Q7ZVV76EI) ; Rivaroxaban (9NDF7JZ4M3)
    Language English
    Publishing date 2019-04-01
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2018-227695
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The critical distinction between characterisation and causation in studies of COVID-19-associated pathology

    Benger, Matthew / Williams, Owain / Siddiqui, Juveria / Sztriha, Laszlo

    Brain behav. immun

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #921828
    Database COVID19

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  7. Article ; Online: The critical distinction between characterisation and causation in studies of COVID-19-associated pathology

    Benger, Matthew / Williams, Owain / Siddiqui, Juveria / Sztriha, Laszlo

    Brain, Behavior, and Immunity ; ISSN 0889-1591

    2020  

    Keywords Immunology ; Behavioral Neuroscience ; Endocrine and Autonomic Systems ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.bbi.2020.11.017
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Intracerebral haemorrhage and COVID-19

    Benger, Matthew / Williams, Owain / Siddiqui, Juveria / Sztriha, Laszlo

    Brain, Behavior, and Immunity

    Clinical characteristics from a case series

    2020  Volume 88, Page(s) 940–944

    Keywords Immunology ; Behavioral Neuroscience ; Endocrine and Autonomic Systems ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 639219-2
    ISSN 0889-1591
    ISSN 0889-1591
    DOI 10.1016/j.bbi.2020.06.005
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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