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  1. AU="Bennett, Matthew R"
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  1. Article ; Online: Insights Into Informal Caregivers' Well-being: A Longitudinal Analysis of Care Intensity, Care Location, and Care Relationship.

    Zhang, Yanan / Bennett, Matthew R

    The journals of gerontology. Series B, Psychological sciences and social sciences

    2024  Volume 79, Issue 2

    Abstract: Objectives: This study investigates the psychological well-being of informal caregivers over time. It identifies the thresholds (or "tipping points") of caring intensity at which caregiving is associated with lower psychological well-being, and how this ...

    Abstract Objectives: This study investigates the psychological well-being of informal caregivers over time. It identifies the thresholds (or "tipping points") of caring intensity at which caregiving is associated with lower psychological well-being, and how this varies by care location and caregiver-care recipient relationships. It also examines how caring location and relationship are linked to informal caregivers' psychological well-being while controlling for caring intensity.
    Methods: Waves 1-18 (1991-2009) of the harmonized British Household Panel Survey and Waves 1-8 (2009-2017) of the U.K. Household Longitudinal Study were analyzed. Psychological well-being was measured using the General Health Questionnaire (GHQ)-12 score. Care intensity was measured by the weekly hours of care provided. Fixed-effects estimators were applied to the GHQ-12 score of caregivers across different care intensities, caring locations, and caring relationships.
    Results: All levels of informal care intensity are associated with lower psychological well-being among spousal caregivers. The thresholds to well-being are 5 hours per week when caring for a parent, and 50 hours per week when caring for a child (with a disability or long-term illness). Caring for "other relatives" or nonrelatives is not negatively associated with psychological well-being. The thresholds are 5 hours per week for both coresident and extraresident caregivers. Extraresident caregivers experience better psychological well-being compared to coresident caregivers, given relatively lower weekly care hours. Caring for primary kin (especially spouses) is linked to lower psychological well-being compared to other caregiving relationships, regardless of care intensity.
    Discussion: Policy and practice responses should pay particular attention to spousal caregivers' well-being. Caregiving relationship has a stronger association with the caregiver's well-being than care location.
    MeSH term(s) Humans ; Caregivers/psychology ; Longitudinal Studies ; Psychological Well-Being
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1223664-0
    ISSN 1758-5368 ; 1079-5014
    ISSN (online) 1758-5368
    ISSN 1079-5014
    DOI 10.1093/geronb/gbad166
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Recovery of 3D footwear impressions using a range of different techniques.

    Larsen, Hannah J / Bennett, Matthew R

    Journal of forensic sciences

    2021  Volume 66, Issue 3, Page(s) 1056–1064

    Abstract: Three-dimensional (plastic) footwear impressions are frequently found at, or in the vicinity of a crime scene, and may provide a valuable form of evidence or intelligence. This paper compares the traditional methods of casting and/or two-dimensional ... ...

    Abstract Three-dimensional (plastic) footwear impressions are frequently found at, or in the vicinity of a crime scene, and may provide a valuable form of evidence or intelligence. This paper compares the traditional methods of casting and/or two-dimensional photography with Structure from Motion (SfM) photogrammetry. We focus both on the recovery of class characteristics (sole pattern) and randomly acquired characteristics caused by damage. We examine how different recovery techniques influence visualization of outsole features and discuss what effect this may have on evidential value. Five shoes and their associated three-dimensional impressions made in both sand and soil were compared using a grid system and tread descriptors commonly used in the UK. We conclude that within the limitations of this study SfM photogrammetry allows superior levels of visualization of both class and randomly acquired characteristics, giving a better definition in detail in some instances. The use of SfM as a complementary approach can therefore lead to a potential increase in evidential value.
    Language English
    Publishing date 2021-01-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219216-0
    ISSN 1556-4029 ; 0022-1198
    ISSN (online) 1556-4029
    ISSN 0022-1198
    DOI 10.1111/1556-4029.14662
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  3. Article ; Online: Variety Is the Spice of Life: Diverse Social Networks Are Associated With Social Cohesion and Well-Being.

    Ramos, Miguel R / Li, Danying / Bennett, Matthew R / Mogra, Unaysah / Massey, Douglas S / Hewstone, Miles

    Psychological science

    2024  , Page(s) 9567976241243370

    Abstract: Both homophily and heterophily are observed in humans. Homophily reinforces homogeneous social networks, and heterophily creates new experiences and collaborations. However, at the extremes, high levels of homophily can cultivate prejudice toward out- ... ...

    Abstract Both homophily and heterophily are observed in humans. Homophily reinforces homogeneous social networks, and heterophily creates new experiences and collaborations. However, at the extremes, high levels of homophily can cultivate prejudice toward out-groups, whereas high levels of heterophily can weaken in-group support. Using data from 24,726 adults (
    Language English
    Publishing date 2024-04-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2022256-7
    ISSN 1467-9280 ; 0956-7976
    ISSN (online) 1467-9280
    ISSN 0956-7976
    DOI 10.1177/09567976241243370
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  4. Article ; Online: Strategies for Improving Small-Molecule Biosensors in Bacteria.

    Miller, Corwin A / Ho, Joanne M L / Bennett, Matthew R

    Biosensors

    2022  Volume 12, Issue 2

    Abstract: In recent years, small-molecule biosensors have become increasingly important in synthetic biology and biochemistry, with numerous new applications continuing to be developed throughout the field. For many biosensors, however, their utility is hindered ... ...

    Abstract In recent years, small-molecule biosensors have become increasingly important in synthetic biology and biochemistry, with numerous new applications continuing to be developed throughout the field. For many biosensors, however, their utility is hindered by poor functionality. Here, we review the known types of mechanisms of biosensors within bacterial cells, and the types of approaches for optimizing different biosensor functional parameters. Discussed approaches for improving biosensor functionality include methods of directly engineering biosensor genes, considerations for choosing genetic reporters, approaches for tuning gene expression, and strategies for incorporating additional genetic modules.
    MeSH term(s) Bacteria ; Biosensing Techniques ; Synthetic Biology
    Language English
    Publishing date 2022-01-25
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662125-3
    ISSN 2079-6374 ; 2079-6374
    ISSN (online) 2079-6374
    ISSN 2079-6374
    DOI 10.3390/bios12020064
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  5. Article ; Online: Empirical Evaluation of the Reliability of Photogrammetry Software in the Recovery of Three-Dimensional Footwear Impressions.

    Larsen, Hannah J / Bennett, Matthew R

    Journal of forensic sciences

    2020  Volume 65, Issue 5, Page(s) 1722–1729

    Abstract: This paper examines the reliability of Structure from Motion (SfM) photogrammetry as a tool in the capture of forensic footwear marks. This is applicable to photogrammetry freeware DigTrace but is equally relevant to other SfM solutions. SfM simply ... ...

    Abstract This paper examines the reliability of Structure from Motion (SfM) photogrammetry as a tool in the capture of forensic footwear marks. This is applicable to photogrammetry freeware DigTrace but is equally relevant to other SfM solutions. SfM simply requires a digital camera, a scale bar, and a selection of oblique photographs of the trace in question taken at the scene. The output is a digital three-dimensional point cloud of the surface and any plastic trace thereon. The first section of this paper examines the reliability of photogrammetry to capture the same data when repeatedly used on one impression, while the second part assesses the impact of varying cameras. Using cloud to cloud comparisons that measure the distance between two-point clouds, we assess the variability between models. The results highlight how little variability is evident and therefore speak to the accuracy and consistency of such techniques in the capture of three-dimensional traces. Using this method, 3D footwear impressions can, in many substrates, be collected with a repeatability of 97% with any variation between models less than ~0.5 mm.
    Language English
    Publishing date 2020-05-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219216-0
    ISSN 1556-4029 ; 0022-1198
    ISSN (online) 1556-4029
    ISSN 0022-1198
    DOI 10.1111/1556-4029.14455
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  6. Article: A portable regulatory RNA array design enables tunable and complex regulation across diverse bacteria.

    Liu, Baiyang / Samaniego, Christian Cuba / Bennett, Matthew R / Franco, Elisa / Chappell, James

    bioRxiv : the preprint server for biology

    2023  

    Abstract: A lack of composable and tunable gene regulators has hindered efforts to engineer non-model bacteria and consortia. To address this, we explore the broad-host potential of small transcription activating RNA (STAR) and propose a novel design strategy to ... ...

    Abstract A lack of composable and tunable gene regulators has hindered efforts to engineer non-model bacteria and consortia. To address this, we explore the broad-host potential of small transcription activating RNA (STAR) and propose a novel design strategy to achieve tunable gene control. First, we demonstrate that STARs optimized for
    Language English
    Publishing date 2023-02-25
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.02.24.529951
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  7. Article ; Online: Longitudinal analysis of local government spending on adult social care and carers' subjective well-being in England.

    Zhang, Yanan / Bennett, Matthew R / Yeandle, Sue

    BMJ open

    2021  Volume 11, Issue 12, Page(s) e049652

    Abstract: Objectives: Reform of England's social care system is repeatedly discussed in the context of increasing demand, rising costs and austere policies that have decreased service provision. This study investigates the association between unpaid carers' ... ...

    Abstract Objectives: Reform of England's social care system is repeatedly discussed in the context of increasing demand, rising costs and austere policies that have decreased service provision. This study investigates the association between unpaid carers' subjective well-being and local government spending on adult social care (ASC).
    Setting and participants: Our sample consists of 110 188 observations on 29 174 adults in England from the 2004-2007 British Household Panel Survey and the 2009-2018 UK Household Longitudinal Study. The data on local authorities' spending on ASC where participants live is derived from the publications Personal Social Care Expenditure and Unit Costs (2004-2016); and ASC Activity and Finance Report England (2016-2018).
    Outcome measures: Subjective well-being is measured by the 12-item version of the General Health Questionnaire (GHQ-12) and 12-item version of the Mental Component Summary (MCS-12). We applied fixed-effects linear models to investigate the moderating effect of ASC spending on the association between subjective well-being and caring, controlling for a range of socioeconomic and demographic variables.
    Results: Carers have a lower level of subjective well-being compared with non-carers, evident in their higher average GHQ-12 Likert score (β=2.7277 95% CI 0.2547 to 5.2008). Differences in the subjective well-being of carers and non-carers decrease with local government spending on ASC. Subjective well-being for carers was at a similar level to that of non-carers in high ASC spending local authorities (GHQ-12: -0.0123 95% CI -0.2185 to 0.1938, MCS-12: 0.0347 95% CI -0.3403 to 0.4098) and lower in other areas (GHQ-12: 0.1893 95% CI 0.0680 to 0.3107, MCS-12: -0.2906 95% CI -0.5107 to -0.0705). The moderating effect of ASC spending is found among people who care for 35+ hours per week.
    Conclusion: Government spending on ASC protects unpaid carers' well-being, and people providing more than 35 weekly hours of unpaid care are more likely to benefit from the current social care system.
    MeSH term(s) Adult ; Caregivers ; England ; Humans ; Local Government ; Longitudinal Studies ; Social Support
    Language English
    Publishing date 2021-12-23
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2021-049652
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Indirect enrichment of desirable, but less fit phenotypes, from a synthetic microbial community using microdroplet confinement.

    Prabhakar, Ramya Ganiga / Fan, Gaoyang / Alnahhas, Razan N / Hirning, Andrew J / Bennett, Matthew R / Shamoo, Yousif

    bioRxiv : the preprint server for biology

    2023  

    Language English
    Publishing date 2023-01-11
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.01.11.523444
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A portable regulatory RNA array design enables tunable and complex regulation across diverse bacteria.

    Liu, Baiyang / Samaniego, Christian Cuba / Bennett, Matthew R / Franco, Elisa / Chappell, James

    Nature communications

    2023  Volume 14, Issue 1, Page(s) 5268

    Abstract: A lack of composable and tunable gene regulators has hindered efforts to engineer non-model bacteria and consortia. Toward addressing this, we explore the broad-host potential of small transcription activating RNA (STAR) and propose a design strategy to ... ...

    Abstract A lack of composable and tunable gene regulators has hindered efforts to engineer non-model bacteria and consortia. Toward addressing this, we explore the broad-host potential of small transcription activating RNA (STAR) and propose a design strategy to achieve tunable gene control. First, we demonstrate that STARs optimized for E. coli function across different Gram-negative species and can actuate using phage RNA polymerase, suggesting that RNA systems acting at the level of transcription are portable. Second, we explore an RNA design strategy that uses arrays of tandem and transcriptionally fused RNA regulators to precisely alter regulator concentration from 1 to 8 copies. This provides a simple means to predictably tune output gain across species and does not require access to large regulatory part libraries. Finally, we show RNA arrays can be used to achieve tunable cascading and multiplexing circuits across species, analogous to the motifs used in artificial neural networks.
    MeSH term(s) Escherichia coli/genetics ; Bacteria/genetics ; Bacteriophages/genetics ; Engineering ; RNA
    Chemical Substances RNA (63231-63-0)
    Language English
    Publishing date 2023-08-29
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, N.I.H., Extramural
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-40785-x
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  10. Article ; Online: Technological innovation in the recovery and analysis of 3D forensic footwear evidence: Structure from motion (SfM) photogrammetry.

    Larsen, Hannah / Budka, Marcin / Bennett, Matthew R

    Science & justice : journal of the Forensic Science Society

    2021  Volume 61, Issue 4, Page(s) 356–368

    Abstract: The recovery of three-dimensional footwear impressions at crime scenes can be a challenge but can also yield important investigative data. Traditional methods involve casting 3D impressions but these methods have limitations: the trace is usually ... ...

    Abstract The recovery of three-dimensional footwear impressions at crime scenes can be a challenge but can also yield important investigative data. Traditional methods involve casting 3D impressions but these methods have limitations: the trace is usually destroyed during capture; the process can be time consuming, with a risk of failure; and the resultant cast is bulky and therefore difficult to share and store. The use of Structure from Motion (SfM) photogrammetry has been used widely to capture fossil footprints in the geological record and while there is a small body of work advocating its use in forensic practice the full potential of this technique has yet to be realised in an operational context. The availability of affordable software is one limiting factor and here we report the availability of a bespoke freeware for SfM recovery and subsequent analysis of for footwear evidence (DigTrace). Our aim here is not to provide a rigorous comparison of SfM methods to other recovery methods, but more to illustrate the potential while also documenting the typical workflows and potential errors associated with an SfM based approach. By doing so we hope to encourage further research, experimentation and ultimately adoption by practitioners.
    MeSH term(s) Forensic Medicine ; Humans ; Imaging, Three-Dimensional/methods ; Inventions ; Photogrammetry ; Software
    Language English
    Publishing date 2021-04-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 1230910-2
    ISSN 1876-4452 ; 1355-0306
    ISSN (online) 1876-4452
    ISSN 1355-0306
    DOI 10.1016/j.scijus.2021.04.003
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