Article: Cancers de la sphère ORL : l’immunothérapie donne de la voix !
2017 Volume 13, Issue 563, Page(s) 1029–1031
Abstract: Immunotherapy, especially checkpoint inhibitors such as anti-PD1 and anti-PDL1 antibodies, has changed the standard of care and the prognosis of melanoma, but also more recently of lung cancer, renal cancer and Hodgkin lymphoma. Results of preliminary ... ...
| Title translation | Head and neck cancer : promising results of immunotherapy. | |||||
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| Abstract | Immunotherapy, especially checkpoint inhibitors such as anti-PD1 and anti-PDL1 antibodies, has changed the standard of care and the prognosis of melanoma, but also more recently of lung cancer, renal cancer and Hodgkin lymphoma. Results of preliminary studies in head and neck squamous cell carcinoma (HNSCC) as well as in less frequent tumors of the region, such as nasopharyngeal carcinoma and high grade salivary gland carcinoma, are also promising. Indeed, in a recent phase 3 study, the PD1 inhibitor nivolumab has recently demonstrated a significant improvement in overall survival for platin-resistant recurrent and/or metastatic HNSCC. |
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| MeSH term(s) | Carcinoma/pathology ; Carcinoma/therapy ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/therapy ; Head and Neck Neoplasms/pathology ; Head and Neck Neoplasms/therapy ; Humans ; Immunotherapy/methods ; Immunotherapy/trends ; Melanoma/pathology ; Melanoma/therapy ; Nasopharyngeal Carcinoma ; Nasopharyngeal Neoplasms/pathology ; Nasopharyngeal Neoplasms/therapy ; Squamous Cell Carcinoma of Head and Neck | |||||
| Language | French | |||||
| Publishing date | 2017-06-21 | |||||
| Publishing country | Switzerland | |||||
| Document type | Journal Article ; Review | |||||
| ZDB-ID | 2177010-4 | |||||
| ISSN | 1660-9379 | |||||
| ISSN | 1660-9379 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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