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  1. Article ; Online: Evaluation of the decision support system for antimicrobial treatment, TREAT, in an acute medical ward of a university hospital

    Bente Arboe / Rasmus Rude Laub / Gitte Kronborg / Jenny Dahl Knudsen

    International Journal of Infectious Diseases, Vol 29, Iss C, Pp 156-

    2014  Volume 161

    Abstract: Objectives: TREAT, a decision support system for antimicrobial therapy, was implemented in an acute medical ward. Methods: Patients admitted on suspicion of infection were included in the study. The evaluation of TREAT was done both retrospectively and ... ...

    Abstract Objectives: TREAT, a decision support system for antimicrobial therapy, was implemented in an acute medical ward. Methods: Patients admitted on suspicion of infection were included in the study. The evaluation of TREAT was done both retrospectively and prospectively. Coverage of empirical antimicrobial treatments was compared to recommendations from TREAT and the optimal use of local guidelines. Results: Five hundred and eleven patients were included, of whom 162 had a microbiologically documented infection. In the retrospective part of the study, TREAT, physician, and guideline antimicrobial coverage rates were 65%, 51%, and 79%, respectively, and in the prospective part, 68%, 62%, and 77%, respectively. TREAT provided lower coverage than local guidelines (p < 0.001), but was similar to the performance of physicians in a university hospital (p = 0.069). No differences were found in length of hospital stay, or hospital or 30-day mortality. Direct costs were significantly higher for TREAT advice than for local guidelines or the physician prescriptions (p < 0.001), but the ecological costs were lower for TREAT advice than for both local guidelines (p < 0.001) and physician prescriptions (p = 0.247). The coverage of TREAT advice for the bacteraemia patients was non-inferior to the physicians (p = 1.00). Conclusions: TREAT can potentially improve the ecological costs of empirical antimicrobial therapy for patients in acute medical wards, but provided lower coverage than local guidelines.
    Keywords TREAT ; Antimicrobial treatment ; Decision support system ; Acute medicine ; Infection ; Infectious and parasitic diseases ; RC109-216
    Language English
    Publishing date 2014-12-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: The Danish National Lymphoma Registry

    Bente Arboe / Tarec Christoffer El-Galaly / Michael Roost Clausen / Peter Svenssen Munksgaard / Danny Stoltenberg / Mette Kathrine Nygaard / Tobias Wirenfeldt Klausen / Jacob Haaber Christensen / Jette Sønderskov Gørløv / Peter de Nully Brown

    PLoS ONE, Vol 11, Iss 6, p e

    Coverage and Data Quality.

    2016  Volume 0157999

    Abstract: BACKGROUND:The Danish National Lymphoma Register (LYFO) prospectively includes information on all lymphoma patients newly diagnosed at hematology departments in Denmark. The validity of the clinical information in the LYFO has never been systematically ... ...

    Abstract BACKGROUND:The Danish National Lymphoma Register (LYFO) prospectively includes information on all lymphoma patients newly diagnosed at hematology departments in Denmark. The validity of the clinical information in the LYFO has never been systematically assessed. AIM:To test the coverage and data quality of the LYFO. METHODS:The coverage was tested by merging data of the LYFO with the Danish Cancer Register and the Danish National Patient Register, respectively. The validity of the LYFO was assessed by crosschecking with information from medical records in subgroups of patients. A random sample of 3% (N = 364) was made from all patients in the LYFO. In addition, four subtypes of lymphomas were validated: CNS lymphomas, diffuse large B-cell lymphomas, peripheral T-cell lymphomas, and Hodgkin lymphomas. A total of 1,706 patients from the period 2000-2012 were included. The positive predictive values (PPVs) and completeness of selected variables were calculated for each subgroup and for the entire cohort of patients. RESULTS:The comparison of data from the LYFO with the Danish Cancer Register and the Danish National Patient Register revealed a high coverage. In addition, the data quality was good with high PPVs (87% to 100%), and high completeness (92% to 100%). CONCLUSION:The LYFO is a unique, nationwide clinical database characterized by high validity, good coverage and prospective data entry. It represents a valuable resource for future lymphoma research.
    Keywords Medicine ; R ; Science ; Q
    Subject code 610
    Language English
    Publishing date 2016-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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