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Article: Non-obstetric surgery during gestation: risk factors for lower birthweight.

Jenkins, Thomas M / Mackey, Suzanne F / Benzoni, Elisa M / Tolosa, Jorge E / Sciscione, Anthony C

The Australian & New Zealand journal of obstetrics & gynaecology

2003  Volume 43, Issue 1, Page(s) 27–31

Abstract: Objective: To assess the risk for preterm birth and low birthweight for women undergoing non-obstetric surgery during gestation.: Design: Two perinatal tertiary care centres.: Population: Women undergoing non-obstetric surgery during gestation ... ...

Abstract Objective: To assess the risk for preterm birth and low birthweight for women undergoing non-obstetric surgery during gestation.
Design: Two perinatal tertiary care centres.
Population: Women undergoing non-obstetric surgery during gestation between January 1989 and June 1999.
Materials and methods: A chart review was carried out. Cervical cerclages, procedures carried out under local anaesthesia or intravenous sedation, or carried out in combination with Caesarean delivery were excluded.
Main outcome measures: Preterm birth (<37 weeks), birthweight.
Results: A total of 116 of 69 800 women (0.2%) underwent non-obstetric surgery, with 96 women delivering under our care. Procedures were more commonly carried out in the second trimester (53%), versus the first (23%) or third trimester (24%). Surgery in the second trimester resulted in the lowest rate of preterm birth (11%). The overall preterm birth rate was 21% (20/96), with 13 out of 20 (65%) occurring between 35 and 37 weeks. The mean interval from surgery to delivery was 18.7 weeks. Rates of preterm birth were similar for either intra- versus extra-abdominal procedures, or general versus regional anaesthetic. Use of a general anaesthetic was associated with a significant decrease in birthweight (3053 vs 3515 g, P = 0.01) despite similar gestational ages at delivery (37.6 vs 38.6 weeks, P = 0.08). Multiple linear regression controlled for gestational age showed that general anaesthesia, longer surgery duration, and intra-abdominal procedures were all significant independent risk factors for lower birthweight.
Conclusion: While non-obstetric surgery appears to be relatively safe during gestation, general anaesthesia, longer surgery time, and intra-abdominal procedures are associated with lower birthweights.
MeSH term(s) Anesthesia, General ; Birth Weight ; Female ; Humans ; Linear Models ; Obstetric Labor, Premature/epidemiology ; Pregnancy ; Pregnancy Trimester, Second ; Retrospective Studies ; Risk Factors ; Surgical Procedures, Operative ; Time Factors
Language English
Publishing date 2003-05-01
Publishing country Australia
Document type Journal Article ; Multicenter Study
ZDB-ID 390815-x
ISSN 1479-828X ; 0004-8666
ISSN (online) 1479-828X
ISSN 0004-8666
DOI 10.1046/j.0004-8666.2003.00001.x
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