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  1. Article: Occurrence and Characteristics of Cut Injuries in Hedgehogs in Germany: A Collection of Individual Cases.

    Berger, Anne

    Animals : an open access journal from MDPI

    2023  Volume 14, Issue 1

    Abstract: The number of European hedgehogs ( ...

    Abstract The number of European hedgehogs (
    Language English
    Publishing date 2023-12-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani14010057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Diet and wild ungulate preferences of wolves in northwestern Anatolia during winter

    Mengüllüoğlu, Deniz / Berger, Anne

    PeerJ, 7:e7446

    2019  

    Abstract: The gray wolf (Canis lupus) is making a comeback in many habitats in central Europe, where it has been once extirpated. Although densities are still low to moderate, this comeback already raises management concerns. In Anatolia, the gray wolf is one of ... ...

    Institution Leibniz-Institut für Zoo- und Wildtierforschung (Berlin)
    Abstract The gray wolf (Canis lupus) is making a comeback in many habitats in central Europe, where it has been once extirpated. Although densities are still low to moderate, this comeback already raises management concerns. In Anatolia, the gray wolf is one of the most common predator species occupying almost all kind of habitats. Although its numbers were reduced in some parts of the country, it has never been extirpated and lived in sympatry with humans. In this study we investigated, for the first time, the winter diet of wolves in north-west Anatolia, where a multispecies wild ungulate community occurs in sympatry with high density livestock. We selected two geographically close but different habitats (steppe and forest) with different wild prey availabilities and compositions. In both areas ungulate contribution to winter diet biomass was more than 90%. Wolf pack size (four to eight wolves) were higher in the study area where livestock numbers and human disturbance were lower and wild prey were more available. In both study areas, wild boar (Sus scrofa) was the main and most preferred food item (Chesson’s α = 0.7 − 0.9) and it occurred at higher density where wolf pack size was smaller. We could not find a high preference (Chesson’s α = 0.3) and high winter predation pressure on the reintroduced Anatolian wild sheep (Ovis gmelinii anatolica) population that occurs in the study area covered by steppe vegetation. Contribution of livestock and food categories other than wild ungulates to wolf diet stayed low. Wolves can help mitigate human-wildlife conflict regulating wild boar numbers, the most common conflict-causing ungulate species in Anatolia. Instead of managing wolf numbers in human dominated landscapes, we recommend reintroduction of wild ungulates to the areas where they became locally extinct and replaced by livestock.
    Keywords Canis lupus ; Human-wildlife conflict ; Ovis gmelinii anatolica ; Livestock guarding dog ; Sus scrofa ; Population density ; Predator-prey ; Prey preferences
    Language English
    Document type Article
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  3. Article: Music festival makes hedgehogs move: How individuals cope behaviourally in response to human-induced stressors

    Rast, Wanja / Barthel, Leon M.F. / Berger, Anne

    Animals, 9(7):455

    2019  

    Abstract: Understanding the impact of human activities on wildlife behavior and fitness can improve their sustainability. In a pilot study, we wanted to identify behavioral responses to anthropogenic stress in an urban species during a semi-experimental field ... ...

    Institution Leibniz-Institut für Zoo- und Wildtierforschung (Berlin)
    Abstract Understanding the impact of human activities on wildlife behavior and fitness can improve their sustainability. In a pilot study, we wanted to identify behavioral responses to anthropogenic stress in an urban species during a semi-experimental field study. We equipped eight urban hedgehogs (Erinaceus europaeus; four per sex) with bio-loggers to record their behavior before and during a mega music festival (2 × 19 days) in Treptower Park, Berlin. We used GPS (Global Positioning System) to monitor spatial behavior, VHF (Very High Frequency)-loggers to quantify daily nest utilization, and accelerometers to distinguish between different behaviors at a high resolution and to calculate daily disturbance (using Degrees of Functional Coupling). The hedgehogs showed clear behavioral differences between the pre-festival and festival phases. We found evidence supporting highly individual strategies, varying between spatial and temporal evasion of the disturbance. Averaging the responses of the individual animals or only examining one behavioral parameter masked these potentially different individual coping strategies. Using a meaningful combination of different minimal-invasive bio-logger types, we were able to show high inter-individual behavioral variance of urban hedgehogs in response to an anthropogenic disturbance, which might be a precondition to persist successfully in urban environments.
    Keywords Erinaceae ; ODBA ; anthropogenic disturbance ; accelerometry ; behavior recognition ; behavioral flexibility ; non-invasive stress detection ; urban wildlife
    Language English
    Document type Article
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  4. Article: Applied Hedgehog Conservation Research.

    Reeve, Nigel / Berger, Anne / Rasmussen, Sophie Lund

    Animals : an open access journal from MDPI

    2024  Volume 14, Issue 6

    Abstract: Hedgehogs (Order Eulipotyphla, Family Erinaceidae, Subfamily Erinaceinae) are familiar and popular spiny mammals, but they face many challenges in modern human-dominated environments [ ... ]. ...

    Abstract Hedgehogs (Order Eulipotyphla, Family Erinaceidae, Subfamily Erinaceinae) are familiar and popular spiny mammals, but they face many challenges in modern human-dominated environments [...].
    Language English
    Publishing date 2024-03-21
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani14060976
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Online ; Thesis: Mutationsanalyse von EYA1 in einer unselektierten Kohorte von 135 Kindern mit kongenitalen Anomalien der Niere und ableitenden Harnwege (CAKUT)

    Berger, Anne Katrin

    2005  

    Author's details vorgelegt von Anne Katrin Berger
    Language German
    Publishing country Germany
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Hamburg, Univ., Diss., 2006
    HBZ-ID HT014924535
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Article ; Online: Anti-HLA-B7/HLA-B44 strong cross immunoreactivity observed in flow cytometry HLA-B27 immunotyping.

    Francois, Fabien / Waeckel, Louis / Berger, Anne-Emmanuelle / Lambert, Claude

    Cytometry. Part A : the journal of the International Society for Analytical Cytology

    2024  

    Abstract: Cross reactivities are known for human leukocyte antigen inside HLA-B7 related Cross-Reactive Group (B7CREG). Some CE-IVD flow-cytometry kits use double monoclonal antibodies (mAb) to distinguish HLA-B27 and HLA-B7 but practice reveals more complexes ... ...

    Abstract Cross reactivities are known for human leukocyte antigen inside HLA-B7 related Cross-Reactive Group (B7CREG). Some CE-IVD flow-cytometry kits use double monoclonal antibodies (mAb) to distinguish HLA-B27 and HLA-B7 but practice reveals more complexes results. This study explores the performances of this test. Analysis of 466 consecutive cases using HLA-B27 IOTest™ kit on a Navios™ cytometer from Beckman-Coulter, partially compared to their genotypes. Expected haplotypes HLA-B27-/HLA-B7- (undoubtedly HLA-B27 negative) and HLA-B27+/HLA-B7- (undoubtedly HLA-B27+) were clearly identified according to the manufacturer's instructions. On the opposite, patients strongly labeled with anti-HLA-B7 showed three different phenotypes regarding anti-HLA-B27 labeling: (1) most of the cases were poorly labeled in accordance with cross reactivity inside B7CREG (HLA-B27-/HLA-B7+ haplotype); (2) rare cases had strong B7 and B27 labeling corresponding to HLA-B27+/HLA-B7+ haplotype; (3) even less cases had strong labeling by anti-HLA-B7 but non for anti-HLA-B27, all expressing HLA-B44 and no B7CREG molecules. Surprisingly, more cases were not labeled with anti-HLA-B7 antibody but partially labeled with anti-HLA-B27 suggesting another cross reactivity out of B7CREG. mAb HLA typing suggests new, cross reactivities of anti-HLA-B27 antibody to more molecules out of B7CREG and of anti-HLA-B7 antibody but not anti-HLA-B27 to HLA-B44 molecule also out of B7CREG. HLA-B27 could surely be excluded in most samples labeled with HLA-B27, below a "grey zone" on intermediate intensity. More comparison is needed in future studies.
    Language English
    Publishing date 2024-02-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2099868-5
    ISSN 1552-4930 ; 0196-4763 ; 1552-4922
    ISSN (online) 1552-4930
    ISSN 0196-4763 ; 1552-4922
    DOI 10.1002/cyto.a.24824
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1688: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  7. Article ; Online: FRET causing misleading signal from fluorescein excited by the violet laser in flow cytometry.

    Waeckel, Louis / Khenine, Hana / Berger, Anne-Emmanuelle / Lambert, Claude

    Cytometry. Part A : the journal of the International Society for Analytical Cytology

    2023  Volume 103, Issue 9, Page(s) 732–735

    Abstract: Multiple immunolabeling introduces high risks of interferences between fluorescences. As an example, in analyzing T cell clonality, we recently reported a fluorescence resonance energy transfer (FRET) effect providing an unexpected signal on B770 (PE-Cy7) ...

    Abstract Multiple immunolabeling introduces high risks of interferences between fluorescences. As an example, in analyzing T cell clonality, we recently reported a fluorescence resonance energy transfer (FRET) effect providing an unexpected signal on B770 (PE-Cy7) detector, on the Vβ-PE positive CD3 APC-Alexa750+ T cell subsets. Here, we report another FRET effect produced by the violet laser in Vβ-FITC positive CD3-Pacific Blue (PB) T cells providing signal on V550 (Krome Orange; KrO) detector. The study was performed on fresh whole blood, labeled with anti-CD3-PB, CD8-KrO, Vbeta FITC, Vbeta PE, CD4 AA750 then fixed, treated for erythrolysis, and washed before analysis on DxFlex cytometer from Beckman Coulter. Data were analyzed using Kaluza software. Using this panel, we repeatedly observed an added CD8dim-KrO (V550) cell population on all Vβ FITC positive T cells. The unexpected green signal excited by the violet laser was still observed after removing anti-CD8-KrO (FMO) but disappeared where either anti-CD3-PB or anti-Vβ-FITC was removed. The effect was also observed with an anti-TCR gamma delta-FITC labeling, but not with another FITC labeled antibody targeting a protein out of the CD3-TCR complex. The analysis of fluorochrome spectra confirms that PB emission and FITC excitation spectra partly overlap. This observation clearly reminds users that FRET can give misleading results in case of labeling of very close markers with complementary fluorochromes. This risk has to be considered in panel design. These observations clearly highlight the potential for FRET to give misleading results in cases where very close markers are labeled with complementary fluorochromes. This risk must be considered when designing panels. To our knowledge, this is the first description of a FRET between PB and FITC as acceptor thus excited by the violet laser.
    MeSH term(s) Fluorescein ; Fluorescent Dyes ; Fluorescence Resonance Energy Transfer ; Fluorescein-5-isothiocyanate ; Flow Cytometry/methods ; CD3 Complex ; Lasers
    Chemical Substances Fluorescein (TPY09G7XIR) ; Fluorescent Dyes ; Fluorescein-5-isothiocyanate (I223NX31W9) ; CD3 Complex
    Language English
    Publishing date 2023-08-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2099868-5
    ISSN 1552-4930 ; 0196-4763 ; 1552-4922
    ISSN (online) 1552-4930
    ISSN 0196-4763 ; 1552-4922
    DOI 10.1002/cyto.a.24780
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1688: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 68: Show issues

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  8. Book ; Thesis: Präoperatives Management im Rahmen der operativen Behandlung kolorektaler Karzinome

    Berger, Anne

    eine prospektive Qualitätssicherungsstudie

    1995  

    Author's details vorgelegt von Anne Berger
    Language German
    Size 67 Bl. : graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Jena, Univ., Diss., 1996
    HBZ-ID HT007489129
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    97 E 767 order for loan Magazin

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  9. Article ; Online: Providing the basis for a patient-centred and effective screening for cancer-related fatigue (MERLIN study): design of a longitudinal observational study.

    Blickle, Patricia / Haussmann, Alexander / Holzner, Bernhard / Berger, Anne Katrin / Steindorf, Karen / Schmidt, Martina E

    BMJ open

    2023  Volume 13, Issue 9, Page(s) e073802

    Abstract: Introduction: Cancer-related fatigue (CRF) is a frequent and burdensome sequela of cancer and cancer therapies. It can persist from months to years and has a substantial impact on patients' quality of life and functioning. CRF is often still not ... ...

    Abstract Introduction: Cancer-related fatigue (CRF) is a frequent and burdensome sequela of cancer and cancer therapies. It can persist from months to years and has a substantial impact on patients' quality of life and functioning. CRF is often still not adequately diagnosed and insufficiently treated. According to guideline recommendations, patients should be routinely screened for CRF from cancer diagnosis onwards. We will investigate how an effective screening should be designed regarding timing, frequency, screening type and cut-off points.
    Methods and analysis: MERLIN is a longitudinal observational study that will include 300 patients with cancer at the beginning of cancer therapy. The main study centre is the National Center for Tumour Diseases Heidelberg, Germany. Patients answer five items to shortly screen for CRF at high frequency during their therapy and at lower frequency during the post-treatment phase for 18 months. Further, CRF is assessed at wider intervals based on the Cella criteria, the Brief Fatigue Inventory impact scale, the quality of life fatigue questionnaire (QLQ-FA12) and the fatigue and cognitive items of the quality of life core questionnaire (QLQ-C30), both of the European Organisation for Research and Treatment of Cancer. Important psychological, socio-demographical or medical factors, which may exacerbate CRF are assessed. All assessments are performed online. Receiver operating curves, areas under the curve, sensitivity, specificity, positive and negative predictive values and likelihood ratios will be calculated to determine optimal short screening modalities.
    Ethics and dissemination: The study was approved by the ethics committee of the Medical Faculty of the Heidelberg University, Germany (approval number: S-336/2022). Written informed consent is obtained from all participants. The study is conducted in full conformance with the principles of the Declaration of Helsinki. Results will be published in peer-reviewed scientific journals, presented at conferences and communicated to clinical stakeholders to foster the implementation of an effective CRF management.
    Trial registration number: ClinicalTrials.gov; registration number: NCT05448573.
    MeSH term(s) Humans ; Quality of Life ; Neurofibromin 2 ; Early Detection of Cancer ; Neoplasms/complications ; Fatigue/diagnosis ; Fatigue/etiology ; Fatigue/psychology
    Chemical Substances Neurofibromin 2
    Language English
    Publishing date 2023-09-28
    Publishing country England
    Document type Observational Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2023-073802
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Female and male Eurasian lynx have distinct spatial tactics at different life-history stages in a high-density population.

    Mengüllüoğlu, Deniz / Edwards, Sarah / Hofer, Heribert / Berger, Anne

    Ecology and evolution

    2021  Volume 11, Issue 15, Page(s) 10432–10445

    Abstract: Knowledge regarding the spatial behavior of the Eurasian lynx is mainly inferred from populations in Europe. We used GPS telemetry to record the spatial behavior of nine individuals in northwestern Anatolia obtaining eleven home ranges (HRs). Analyses ... ...

    Abstract Knowledge regarding the spatial behavior of the Eurasian lynx is mainly inferred from populations in Europe. We used GPS telemetry to record the spatial behavior of nine individuals in northwestern Anatolia obtaining eleven home ranges (HRs). Analyses revealed the smallest mean HR sizes (n
    Language English
    Publishing date 2021-06-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2635675-2
    ISSN 2045-7758
    ISSN 2045-7758
    DOI 10.1002/ece3.7846
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