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  1. AU="Berger, Jacob"
  2. AU="Shea, Martin J"
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  1. Article ; Online: Do we conceptualize every color we consciously discriminate?

    Berger, Jacob

    Consciousness and cognition

    2012  Volume 21, Issue 2, Page(s) 632–635

    Abstract: Mandik understands color-consciousness conceptualism to be the view that one deploys in a conscious qualitative state concepts for every color consciously discriminated by that state. Some argue that the experimental evidence that we can consciously ... ...

    Abstract Mandik understands color-consciousness conceptualism to be the view that one deploys in a conscious qualitative state concepts for every color consciously discriminated by that state. Some argue that the experimental evidence that we can consciously discriminate barely distinct hues that are presented together but cannot do so when those hues are presented in short succession suggests that we can consciously discriminate colors that we do not conceptualize. Mandik maintains, however, that this evidence is consistent with our deploying a variety of nondemonstrative concepts for those colors and so does not pose a threat to conceptualism. But even if Mandik has shown that we deploy such concepts in these experimental conditions, there are cases of conscious states that discriminate colors but do not involve concepts of those colors. Mandik's arguments sustain only a theory in the vicinity of conceptualism: The view that we possess concepts for every color we can discriminate consciously, but need not deploy those concepts in every conscious act of color discrimination.
    MeSH term(s) Color Perception ; Consciousness ; Humans
    Language English
    Publishing date 2012-06
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 1106647-7
    ISSN 1090-2376 ; 1053-8100
    ISSN (online) 1090-2376
    ISSN 1053-8100
    DOI 10.1016/j.concog.2011.03.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Working Memory and Consciousness: The Current State of Play.

    Persuh, Marjan / LaRock, Eric / Berger, Jacob

    Frontiers in human neuroscience

    2018  Volume 12, Page(s) 78

    Abstract: Working memory (WM), an important posit in cognitive science, allows one to temporarily store and manipulate information in the service of ongoing tasks. WM has been traditionally classified as an explicit memory system-that is, as operating on and ... ...

    Abstract Working memory (WM), an important posit in cognitive science, allows one to temporarily store and manipulate information in the service of ongoing tasks. WM has been traditionally classified as an explicit memory system-that is, as operating on and maintaining only consciously perceived information. Recently, however, several studies have questioned this assumption, purporting to provide evidence for unconscious WM. In this article, we focus on visual working memory (VWM) and critically examine these studies as well as studies of unconscious perception that seem to provide indirect evidence for unconscious WM. Our analysis indicates that current evidence does not support an unconscious WM store, though we offer independent reasons to think that WM may operate on unconsciously perceived information.
    Language English
    Publishing date 2018-03-02
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2425477-0
    ISSN 1662-5161
    ISSN 1662-5161
    DOI 10.3389/fnhum.2018.00078
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Portable Pathogen Diagnostics Using Microfluidic Cartridges Made from Continuous Liquid Interface Production Additive Manufacturing.

    Berger, Jacob / Aydin, Mehmet Y / Stavins, Robert / Heredia, John / Mostafa, Ariana / Ganguli, Anurup / Valera, Enrique / Bashir, Rashid / King, William P

    Analytical chemistry

    2021  Volume 93, Issue 29, Page(s) 10048–10055

    Abstract: Biomedical diagnostics based on microfluidic devices have the potential to significantly benefit human health; however, the manufacturing of microfluidic devices is a key limitation to their widespread adoption. Outbreaks of infectious disease continue ... ...

    Abstract Biomedical diagnostics based on microfluidic devices have the potential to significantly benefit human health; however, the manufacturing of microfluidic devices is a key limitation to their widespread adoption. Outbreaks of infectious disease continue to demonstrate the need for simple, sensitive, and translatable tests for point-of-care use. Additive manufacturing (AM) is an attractive alternative to conventional approaches for microfluidic device manufacturing based on injection molding; however, there is a need for development and validation of new AM process capabilities and materials that are compatible with microfluidic diagnostics. In this paper, we demonstrate the development and characterization of AM cartridges using continuous liquid interface production (CLIP) and investigate process characteristics and capabilities of the AM microfluidic device manufacturing. We find that CLIP accurately produces microfluidic channels as small as 400 μm and that it is possible to routinely produce fluid channels as small as 100 μm with high repeatability. We also developed a loop-mediated isothermal amplification (LAMP) assay for detection of
    MeSH term(s) Escherichia coli/genetics ; Humans ; Microfluidic Analytical Techniques ; Microfluidics ; Molecular Diagnostic Techniques ; Nucleic Acid Amplification Techniques
    Language English
    Publishing date 2021-07-12
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.1c00654
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Culture-free biphasic approach for sensitive detection of Escherichia coli O157:H7 from beef samples.

    Mostafa, Ariana / Ganguli, Anurup / Berger, Jacob / Rayabharam, Archith / Saavedra, Carlos / Aluru, Narayana R / Bashir, Rashid

    Biotechnology and bioengineering

    2021  Volume 118, Issue 11, Page(s) 4516–4529

    Abstract: Foodborne illnesses are a major threat to public health also leading to significant mortality and financial and reputational damage to industry. It is very important to detect pathogen presence in food products early, rapidly, and accurately to avoid ... ...

    Abstract Foodborne illnesses are a major threat to public health also leading to significant mortality and financial and reputational damage to industry. It is very important to detect pathogen presence in food products early, rapidly, and accurately to avoid potential outbreaks and economic loss. However, "gold standard" culture methods, including enrichment of pathogens, can take up to several days. Moreover, the food matrix often interferes with nucleic acid amplification methods of detection, requiring DNA extraction from the sample for successful molecular detection of pathogens. Here, we introduce a "biphasic" amplification method that can achieve high sensitivity detection with background noise from ground beef food samples without culture or other extraction methods in 2.5 h. Homogenized ground beef is dried resulting in an increase in porosity of the dried food matrix to allowing amplification enzymes and primers to access the target DNA and initiate the reaction within the dried food matrix. Using Loop Mediated Isothermal Amplification, we demonstrate the detection of 1-3 cfu of Escherichia coli bacteria in 30 mg of dried food matrix. Our approach significantly lowers the time to result to less than a few hours and have a pronounced impact on reduction of instrumentation complexity and costs.
    MeSH term(s) Animals ; Cattle ; DNA, Bacterial/analysis ; DNA, Bacterial/genetics ; Escherichia coli O157/genetics ; Food Contamination/analysis ; Food Microbiology ; Molecular Diagnostic Techniques ; Nucleic Acid Amplification Techniques ; Red Meat/microbiology
    Chemical Substances DNA, Bacterial
    Language English
    Publishing date 2021-08-26
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 280318-5
    ISSN 1097-0290 ; 0006-3592
    ISSN (online) 1097-0290
    ISSN 0006-3592
    DOI 10.1002/bit.27920
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Portable Pathogen Diagnostics Using Microfluidic Cartridges Made from Continuous Liquid Interface Production Additive Manufacturing

    Berger, Jacob / Aydin, Mehmet Y. / Stavins, Robert / Heredia, John / Mostafa, Ariana / Ganguli, Anurup / Valera, Enrique / Bashir, Rashid / King, William P.

    Analytical chemistry. 2021 July 12, v. 93, no. 29

    2021  

    Abstract: Biomedical diagnostics based on microfluidic devices have the potential to significantly benefit human health; however, the manufacturing of microfluidic devices is a key limitation to their widespread adoption. Outbreaks of infectious disease continue ... ...

    Abstract Biomedical diagnostics based on microfluidic devices have the potential to significantly benefit human health; however, the manufacturing of microfluidic devices is a key limitation to their widespread adoption. Outbreaks of infectious disease continue to demonstrate the need for simple, sensitive, and translatable tests for point-of-care use. Additive manufacturing (AM) is an attractive alternative to conventional approaches for microfluidic device manufacturing based on injection molding; however, there is a need for development and validation of new AM process capabilities and materials that are compatible with microfluidic diagnostics. In this paper, we demonstrate the development and characterization of AM cartridges using continuous liquid interface production (CLIP) and investigate process characteristics and capabilities of the AM microfluidic device manufacturing. We find that CLIP accurately produces microfluidic channels as small as 400 μm and that it is possible to routinely produce fluid channels as small as 100 μm with high repeatability. We also developed a loop-mediated isothermal amplification (LAMP) assay for detection of E. coli from whole blood directly on the CLIP-based AM microfluidic cartridges, with a 50 cfu/μL limit of detection, validating the use of CLIP processes and materials for pathogen detection. The portable diagnostic platform presented in this paper could be used to investigate and validate other AM processes for microfluidic diagnostics and could be an important component of scaling up the diagnostics for current and future infectious diseases and pandemics.
    Keywords Escherichia coli ; analytical chemistry ; blood ; detection limit ; diagnostic techniques ; human health ; infectious diseases ; injection molding ; liquids ; loop-mediated isothermal amplification ; microbial detection ; pathogens ; point-of-care systems
    Language English
    Dates of publication 2021-0712
    Size p. 10048-10055.
    Publishing place American Chemical Society
    Document type Article
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.1c00654
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: Nanocavity-Enhanced Giant Stimulated Raman Scattering in Si Nanowires in the Visible Light Region.

    Agarwal, Daksh / Ren, Ming-Liang / Berger, Jacob S / Yoo, Jinkyoung / Pan, Anlian / Agarwal, Ritesh

    Nano letters

    2019  Volume 19, Issue 2, Page(s) 1204–1209

    Abstract: Silicon photonics has been a very active area of research especially in the past two decades in order to meet the ever-increasing demand for more computational power and faster device speeds and their natural compatibility with complementary metal-oxide ... ...

    Abstract Silicon photonics has been a very active area of research especially in the past two decades in order to meet the ever-increasing demand for more computational power and faster device speeds and their natural compatibility with complementary metal-oxide semiconductor. In order to develop Si as a useful photonics material, essential photonic components such as light sources, waveguides, wavelength convertors, modulators, and detectors need to be developed and integrated. However, due to the indirect electronic bandgap of Si, conventional light emission devices such as light-emitting diodes and lasers cannot be built. Therefore, there has been considerable interest in developing Si-based Raman lasers, which are nonlinear devices and require large stimulated Raman scattering (SRS) in an optical cavity. However, due to the low quantum yield of SRS in Si, Raman lasers have very large device footprints and high lasing threshold, making them unsuitable for faster, smaller, and energy-efficient devices. Here, we report strong SRS and extremely high Raman gain in Si nanowire optical cavities in the visible region with measured SRS threshold as low as 30 kW/cm
    Language English
    Publishing date 2019-01-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ISSN 1530-6992
    ISSN (online) 1530-6992
    DOI 10.1021/acs.nanolett.8b04666
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Rapid, multiplexed detection of biomolecules using electrically distinct hydrogel beads.

    Cowell, Thomas W / Valera, Enrique / Jankelow, Aaron / Park, Joonhyuck / Schrader, Alex W / Ding, Ruihua / Berger, Jacob / Bashir, Rashid / Han, Hee-Sun

    Lab on a chip

    2020  Volume 20, Issue 13, Page(s) 2274–2283

    Abstract: Rapid, low-cost, and multiplexed biomolecule detection is an important goal in the development of effective molecular diagnostics. Our recent work has demonstrated a microfluidic biochip device that can electrically quantitate a protein target with high ... ...

    Abstract Rapid, low-cost, and multiplexed biomolecule detection is an important goal in the development of effective molecular diagnostics. Our recent work has demonstrated a microfluidic biochip device that can electrically quantitate a protein target with high sensitivity. This platform detects and quantifies a target analyte by counting and capturing micron-sized beads in response to an immunoassay on the bead surface. Existing microparticles limit the technique to the detection of a single protein target and lack the magnetic properties required for separation of the microparticles for direct measurements from whole blood. Here, we report new precisely engineered microparticles that achieve electrical multiplexing and adapt this platform for low-cost and label-free multiplexed electrical detection of biomolecules. Droplet microfluidic synthesis yielded highly-monodisperse populations of magnetic hydrogel beads (MHBs) with the necessary properties for multiplexing the electrical Coulter counting on chip. Each bead population was designed to contain a different amount of the hydrogel material, resulting in a unique electrical impedance signature during Coulter counting, thereby enabling unique identification of each bead. These monodisperse bead populations span a narrow range of sizes ensuring that all can be captured sensitively and selectively under simultaneously flow. Incorporating these newly synthesized beads, we demonstrate versatile and multiplexed biomolecule detection of proteins or DNA targets. This development of multiplexed beads for the electrical detection of biomolecules, provides a critical advancement towards multiplexing the Coulter counting approach and the development of a low cost point-of-care diagnostic sensor.
    MeSH term(s) Hydrogels ; Immunoassay ; Immunomagnetic Separation ; Lab-On-A-Chip Devices ; Microfluidics
    Chemical Substances Hydrogels
    Language English
    Publishing date 2020-05-04
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2056646-3
    ISSN 1473-0189 ; 1473-0197
    ISSN (online) 1473-0189
    ISSN 1473-0197
    DOI 10.1039/d0lc00243g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Strong modulation of second-harmonic generation with very large contrast in semiconducting CdS via high-field domain.

    Ren, Ming-Liang / Berger, Jacob S / Liu, Wenjing / Liu, Gerui / Agarwal, Ritesh

    Nature communications

    2018  Volume 9, Issue 1, Page(s) 186

    Abstract: Dynamic control of nonlinear signals is critical for a wide variety of optoelectronic applications, such as signal processing for optical computing. However, controlling nonlinear optical signals with large modulation strengths and near-perfect contrast ... ...

    Abstract Dynamic control of nonlinear signals is critical for a wide variety of optoelectronic applications, such as signal processing for optical computing. However, controlling nonlinear optical signals with large modulation strengths and near-perfect contrast remains a challenging problem due to intrinsic second-order nonlinear coefficients via bulk or surface contributions. Here, via electrical control, we turn on and tune second-order nonlinear coefficients in semiconducting CdS nanobelts from zero to up to 151 pm V
    Language English
    Publishing date 2018--15
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ISSN 2041-1723
    ISSN (online) 2041-1723
    DOI 10.1038/s41467-017-02548-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Family planning in China

    Berger, Jacob

    Far Eastern affairs : a Russian journal on China, Japan and Asia-Pacific Region ; a quarterly publication of the Institute for Far Eastern Studies, Russian Academy of Sciences , No. 2 , p. 31-46

    looking back and ahead, [Teil 1]

    2001  , Issue 2, Page(s) 31–46

    Author's details Jacob Berger
    Keywords Familienplanung ; China
    Language English ; Russian
    Publisher East View Publ.
    Publishing place Minneapolis, Minn.
    Document type Article
    Note Aus dem Russ. übers.
    ZDB-ID 197557-2
    Database ECONomics Information System

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  10. Article: Family planning in China

    Berger, Jacob

    Far Eastern affairs : a Russian journal on China, Japan and Asia-Pacific Region ; a quarterly publication of the Institute for Far Eastern Studies, Russian Academy of Sciences , No. 3 , p. 71-90

    looking back and ahead, [Teil 2]

    2001  , Issue 3, Page(s) 71–90

    Author's details Jacob Berger
    Keywords Familienplanung ; China
    Language English ; Russian
    Publisher East View Publ.
    Publishing place Minneapolis, Minn.
    Document type Article
    Note Aus dem Russ. übers.
    ZDB-ID 197557-2
    Database ECONomics Information System

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