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  1. Article ; Online: Association between children's emotional/behavioral problems before adenotonsillectomy and postoperative pain scores at home: Answer to a comment.

    Berghmans, Johan / Utens, Elisabeth

    Paediatric anaesthesia

    2020  Volume 30, Issue 2, Page(s) 198–199

    MeSH term(s) Adenoidectomy ; Child ; Emotions ; Humans ; Pain, Postoperative ; Problem Behavior ; Tonsillectomy
    Language English
    Publishing date 2020-02-20
    Publishing country France
    Document type Letter
    ZDB-ID 1086049-6
    ISSN 1460-9592 ; 1155-5645
    ISSN (online) 1460-9592
    ISSN 1155-5645
    DOI 10.1111/pan.13794
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Exploratory Outlier Detection for Acceleromyographic Neuromuscular Monitoring: Machine Learning Approach.

    Verdonck, Michaël / Carvalho, Hugo / Berghmans, Johan / Forget, Patrice / Poelaert, Jan

    Journal of medical Internet research

    2021  Volume 23, Issue 6, Page(s) e25913

    Abstract: Background: Perioperative quantitative monitoring of neuromuscular function in patients receiving neuromuscular blockers has become internationally recognized as an absolute and core necessity in modern anesthesia care. Because of their kinetic nature, ... ...

    Abstract Background: Perioperative quantitative monitoring of neuromuscular function in patients receiving neuromuscular blockers has become internationally recognized as an absolute and core necessity in modern anesthesia care. Because of their kinetic nature, artifactual recordings of acceleromyography-based neuromuscular monitoring devices are not unusual. These generate a great deal of cynicism among anesthesiologists, constituting an obstacle toward their widespread adoption. Through outlier analysis techniques, monitoring devices can learn to detect and flag signal abnormalities. Outlier analysis (or anomaly detection) refers to the problem of finding patterns in data that do not conform to expected behavior.
    Objective: This study was motivated by the development of a smartphone app intended for neuromuscular monitoring based on combined accelerometric and angular hand movement data. During the paired comparison stage of this app against existing acceleromyography monitoring devices, it was noted that the results from both devices did not always concur. This study aims to engineer a set of features that enable the detection of outliers in the form of erroneous train-of-four (TOF) measurements from an acceleromyographic-based device. These features are tested for their potential in the detection of erroneous TOF measurements by developing an outlier detection algorithm.
    Methods: A data set encompassing 533 high-sensitivity TOF measurements from 35 patients was created based on a multicentric open label trial of a purpose-built accelero- and gyroscopic-based neuromuscular monitoring app. A basic set of features was extracted based on raw data while a second set of features was purpose engineered based on TOF pattern characteristics. Two cost-sensitive logistic regression (CSLR) models were deployed to evaluate the performance of these features. The final output of the developed models was a binary classification, indicating if a TOF measurement was an outlier or not.
    Results: A total of 7 basic features were extracted based on raw data, while another 8 features were engineered based on TOF pattern characteristics. The model training and testing were based on separate data sets: one with 319 measurements (18 outliers) and a second with 214 measurements (12 outliers). The F1 score (95% CI) was 0.86 (0.48-0.97) for the CSLR model with engineered features, significantly larger than the CSLR model with the basic features (0.29 [0.17-0.53]; P<.001).
    Conclusions: The set of engineered features and their corresponding incorporation in an outlier detection algorithm have the potential to increase overall neuromuscular monitoring data consistency. Integrating outlier flagging algorithms within neuromuscular monitors could potentially reduce overall acceleromyography-based reliability issues.
    Trial registration: ClinicalTrials.gov NCT03605225; https://clinicaltrials.gov/ct2/show/NCT03605225.
    MeSH term(s) Accelerometry ; Humans ; Machine Learning ; Neuromuscular Blockade ; Neuromuscular Monitoring ; Reproducibility of Results
    Language English
    Publishing date 2021-05-31
    Publishing country Canada
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2028830-X
    ISSN 1438-8871 ; 1439-4456
    ISSN (online) 1438-8871
    ISSN 1439-4456
    DOI 10.2196/25913
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Development and validation of an android-based application for anaesthesia neuromuscular monitoring.

    Carvalho, Hugo / Verdonck, Michael / Berghmans, Johan / Poelaert, Jan

    Journal of clinical monitoring and computing

    2018  Volume 33, Issue 5, Page(s) 863–870

    Abstract: Quantitative neuromuscular block (NMB) assessment is an internationally recognised necessity in anesthesia care whenever neuromuscular blocking agents are administered. Despite this, the incidence of residual neuromuscular block and its associated major ... ...

    Abstract Quantitative neuromuscular block (NMB) assessment is an internationally recognised necessity in anesthesia care whenever neuromuscular blocking agents are administered. Despite this, the incidence of residual neuromuscular block and its associated major respiratory morbidity and mortality remain unacceptably high considering its preventable nature. Recent surveys show that quantitative NMB assessment is not consistently employed by anesthesiologists. Availability, price and practical concerns are some of the factors determining this phenomenon. Clinically assess and validate an Android cell phone application conceived specifically for NMB Monitoring in the anesthesia setting. Twenty-two adult ASA I to III patients scheduled to undergo elective surgical procedures under general anaesthesia requiring administration of a neuromuscular blocking agent were included. After anaesthesia induction, the grade of neuromuscular block was assessed at multiple independent time-points by paired comparison of the train of four (TOF) Ratios obtained by a Stimpod™ accelerometer and the currently developed application. Accelerometric measurements were made at the patient's hand after retrograde supramaximal stimulation of the ipsilateral ulnar nerve. TOF-ratios were subjected to bias analysis with 0.001 as the a priori established clinical significance cut-off. The difference between the two methods averaged 0.0004 (95% limits of agreement: ± 0.12), with 83.3% of the differences being under 0.05. This average inter-method difference was not significantly different than the a priori hypothesized difference cut-off of 0.001 (p = 0.78). Lin's concordance correlation coefficient and Pearson's correlation were both of 0.98. The custom developed Android application proved accurate for diagnosis of residual neuromuscular block.
    MeSH term(s) Accelerometry ; Androstanols/administration & dosage ; Anesthesia ; Anesthesia, General ; Anesthesiology ; Delayed Emergence from Anesthesia/diagnosis ; Female ; Humans ; Longitudinal Studies ; Male ; Mobile Applications ; Monitoring, Intraoperative/instrumentation ; Monitoring, Intraoperative/methods ; Neuromuscular Blockade/methods ; Neuromuscular Monitoring/methods ; Neuromuscular Nondepolarizing Agents/administration & dosage ; Prospective Studies ; Reproducibility of Results ; Smartphone ; User-Computer Interface
    Chemical Substances Androstanols ; Neuromuscular Nondepolarizing Agents
    Language English
    Publishing date 2018-11-16
    Publishing country Netherlands
    Document type Clinical Trial ; Journal Article ; Validation Study
    ZDB-ID 1418733-4
    ISSN 1573-2614 ; 1387-1307 ; 0748-1977
    ISSN (online) 1573-2614
    ISSN 1387-1307 ; 0748-1977
    DOI 10.1007/s10877-018-0224-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Neuromuscular-blocking agents for tracheal intubation in pediatric patients (0-12 years): A systematic review and meta-analysis.

    Vanlinthout, Luc E / Geniets, Bénédicte / Driessen, Jacques J / Saldien, Vera / Lapré, Raphaël / Berghmans, Johan / Uwimpuhwe, Germaine / Hens, Niel

    Paediatric anaesthesia

    2020  Volume 30, Issue 4, Page(s) 401–414

    Abstract: Background: The benefit of using neuromuscular-blocking agents to facilitate tracheal intubation in pediatric patients remains unclear due to variations in design, treatments, and results among trials. By combining the available evidence, we aimed to ... ...

    Abstract Background: The benefit of using neuromuscular-blocking agents to facilitate tracheal intubation in pediatric patients remains unclear due to variations in design, treatments, and results among trials. By combining the available evidence, we aimed to establish whether scientific findings are consistent and can be generalized across various populations, settings, and treatments.
    Methods: A systematic search for randomized controlled trials, related to the use of neuromuscular-blocking agents for tracheal intubation in American Society of Anesthesiologists class I-II participants (0-12 years), was performed. We considered all randomized controlled trials that studied whether intubation conditions and hemodynamics obtained by using neuromuscular-blocking agents were equivalent to those that were achieved without neuromuscular-blocking agents. We combined the outcomes in Review Manager 5.3 (RevMan, The Cochrane Collaboration) by pairwise random-effects meta-analysis using a risk ratio (RR) for intubation conditions and mean difference for hemodynamic values (mean [95% Confidence Intervals]). Heterogeneity among trials was explored using sensitivity analyses.
    Results: We identified 22 eligible randomized controlled trials with 1651 participants. Overall, the use of a neuromuscular-blocking agent was associated with a clinically important increase in the likelihood of both excellent (RR = 1.41 [1.19-1.68], I
    Conclusion: The use of a neuromuscular-blocking agent during light-to-moderate depth of anesthesia can improve the quality as well as the success rate of tracheal intubation and is associated with better hemodynamic stability during induction of anesthesia.
    MeSH term(s) Child ; Humans ; Intubation, Intratracheal/methods ; Neuromuscular Blocking Agents/administration & dosage ; Pediatrics/methods
    Chemical Substances Neuromuscular Blocking Agents
    Language English
    Publishing date 2020-03-09
    Publishing country France
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 1086049-6
    ISSN 1460-9592 ; 1155-5645
    ISSN (online) 1460-9592
    ISSN 1155-5645
    DOI 10.1111/pan.13806
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Des soins bucco-dentaires de qualité: une matière complexe.

    Mortelmans, E / Berghmans, J / Justens, M

    Revue belge de medecine dentaire

    2008  Volume 63, Issue 3, Page(s) 108–124

    Abstract: Assessing the quality of dental care depends on the approach. From the patient's perspective the perception of the quality of care depends as much on the pure technical quality of the treatment as on the level of patient - doctor communication, ... ...

    Title translation Quality dental care: a complex subject.
    Abstract Assessing the quality of dental care depends on the approach. From the patient's perspective the perception of the quality of care depends as much on the pure technical quality of the treatment as on the level of patient - doctor communication, organisation and administration experienced in relation to the treatment. From the point of view of the dental professionals who tend to focus primarily on outcome of treatment on the other hand, this way of patient's judging integrated quality of care might be quite frustrating. After all, thanks to verbal and organisational skills, making good impression despite bad diagnostic and treatment quality might come within reach of simply every dental professional. As desirable it might be, is it possible anyhow to measure if the ultimate quality of care meets the standards of care patients deserve? Certifying outcome of treatment is difficult since it depends on too much variables amongst which some (such as patient's compliance) might fall out of reach of control of the dental care professionals. That's why modern clinical guidelines and protocols stress on creating the ideal treatment steps and conditions most likely leading to the most favourable treatment result. Finally authorities and policymakers aspire more and more to the idea of indicators measuring clinical quality of care from a cost effectiveness point of view. In this respect the authors state that cheap high quality dental care for everybody has become out of date in the actual context. And defining limits to quality of care in order to gain affordability or accessibility, is going to be a tricky exercise requiring sound scientific thinking balanced with ethics.
    MeSH term(s) Belgium ; Clinical Competence ; Clinical Governance ; Cost-Benefit Analysis ; Dental Care/standards ; Dentist-Patient Relations ; Evidence-Based Dentistry ; Health Care Rationing ; Health Services Accessibility ; Humans ; Quality of Health Care
    Language French
    Publishing date 2008
    Publishing country Belgium
    Document type English Abstract ; Journal Article
    ZDB-ID 962534-3
    ISSN 0775-0293 ; 0035-080X
    ISSN 0775-0293 ; 0035-080X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Calculation of the upper flammability limit of methane/air mixtures at elevated pressures and temperatures.

    Van den Schoor, F / Verplaetsen, F / Berghmans, J

    Journal of hazardous materials

    2008  Volume 153, Issue 3, Page(s) 1301–1307

    Abstract: Four different numerical methods to calculate the upper flammability limit of methane/air mixtures at initial pressures up to 10 bar and initial temperatures up to 200 degrees C are evaluated by comparison with experimental data. Planar freely ... ...

    Abstract Four different numerical methods to calculate the upper flammability limit of methane/air mixtures at initial pressures up to 10 bar and initial temperatures up to 200 degrees C are evaluated by comparison with experimental data. Planar freely propagating flames are calculated with the inclusion of a radiation heat loss term in the energy conservation equation to numerically obtain flammability limits. Three different reaction mechanisms are used in these calculations. At atmospheric pressure, the results of these calculations are satisfactory. At elevated pressures, however, large discrepancies are found. The spherically expanding flame calculations only show a marginal improvement compared with the planar flame calculations. On the other hand, the application of a limiting burning velocity with a pressure dependence Su,lim approximately p(-1/2) is found to predict the pressure dependence of the upper flammability limit very well, whereas the application of a constant limiting flame temperature is found to slightly underestimate the temperature dependence of the upper flammability limit.
    MeSH term(s) Air ; Atmospheric Pressure ; Hazardous Substances ; Methane/chemistry ; Temperature
    Chemical Substances Hazardous Substances ; Methane (OP0UW79H66)
    Language English
    Publishing date 2008-05-30
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2007.09.088
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Working fluid safety

    Berghmans, J

    annex 20

    (IEA heat pump programme : Report HPP-AN ; 20-1)

    1994  

    Author's details J. Berghmans
    Series title IEA heat pump programme : Report HPP-AN ; 20-1
    Language English
    Size XII, 151 S
    Publisher IEA Heat Pump Centre
    Publishing place Sittard
    Document type Book
    ISBN 9073741106 ; 9789073741102
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  8. Book: Energie d'ignition lors d'explosions de poussières

    Berghmans, J

    (Dossier technique : ANPI DT ; 83)

    1990  

    Author's details par J. Berghmans
    Series title Dossier technique : ANPI DT ; 83
    Language French
    Size 14 S
    Publisher ANPI
    Publishing place Ottignies
    Document type Book
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  9. Book: High temperature industrial heat pumps

    Berghmans, J

    final report

    (EUR : Energy ; 12695)

    1990  

    Author's details J. Berghmans
    Series title EUR : Energy ; 12695
    Language English
    Size VII, 125 S, graph. Darst
    Publisher Commission of the European Communities
    Publishing place Brussels
    Document type Book
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  10. Article: Ultrasound as guidance for a combined bilateral supraclavicular and caudal block, in order to reduce the total anaesthetic dose in a two year old child after a pneumococcal sepsis.

    Vermeylen, K / Berghmans, J / Van de Velde, M / De Leeuw, T / Himpe, D

    Acta anaesthesiologica Belgica

    2011  Volume 62, Issue 3, Page(s) 151–155

    Abstract: We present a case of the combination of a bilateral supraclavicular block and a caudal block in a two year old boy who needed amputations of four extremities after a pneumococcal sepsis. With the use of ultrasound guidance, reduction of local anaesthetic ...

    Abstract We present a case of the combination of a bilateral supraclavicular block and a caudal block in a two year old boy who needed amputations of four extremities after a pneumococcal sepsis. With the use of ultrasound guidance, reduction of local anaesthetic dose could be obtained in order not to reach the toxic dose of the local anaesthetic. Amputations of four extremities is not common practice. A good postoperative pain management is more than a challenge.
    MeSH term(s) Anesthesia, Caudal/methods ; Anesthetics/administration & dosage ; Brachial Plexus/diagnostic imaging ; Child, Preschool ; Humans ; Male ; Meningitis, Pneumococcal/complications ; Nerve Block/methods ; Shock, Septic/complications ; Subclavian Artery/diagnostic imaging ; Ultrasonography
    Chemical Substances Anesthetics
    Language English
    Publishing date 2011
    Publishing country Belgium
    Document type Case Reports ; Journal Article
    ZDB-ID 80001-6
    ISSN 0001-5164
    ISSN 0001-5164
    Database MEDical Literature Analysis and Retrieval System OnLINE

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