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  1. Article ; Online: Correction to: Echoes of ancient DNA in living modern humans affect risk for neuropsychiatric disease and brain structure and function of networks subserving higher-order cognition.

    Gregory, Michael D / Berman, Karen F

    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

    2022  Volume 47, Issue 12, Page(s) 2173

    Language English
    Publishing date 2022-09-01
    Publishing country England
    Document type Published Erratum
    ZDB-ID 639471-1
    ISSN 1740-634X ; 0893-133X
    ISSN (online) 1740-634X
    ISSN 0893-133X
    DOI 10.1038/s41386-022-01439-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Echoes of ancient DNA in living modern humans affect risk for neuropsychiatric disease and brain structure and function of networks subserving higher-order cognition.

    Gregory, Michael D / Berman, Karen F

    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

    2022  Volume 48, Issue 1, Page(s) 236–237

    MeSH term(s) Humans ; DNA, Ancient ; Cognition ; Brain
    Chemical Substances DNA, Ancient
    Language English
    Publishing date 2022-07-30
    Publishing country England
    Document type News ; Research Support, N.I.H., Intramural
    ZDB-ID 639471-1
    ISSN 1740-634X ; 0893-133X
    ISSN (online) 1740-634X
    ISSN 0893-133X
    DOI 10.1038/s41386-022-01396-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Society of Biological Psychiatry's 75th Anniversary Meeting: A Guide to the Meeting That Wasn't.

    Berman, Karen F / Ford, Judy

    Biological psychiatry

    2020  Volume 87, Issue 9S, Page(s) A11

    Keywords covid19
    Language English
    Publishing date 2020-02-29
    Publishing country United States
    Document type Editorial
    ZDB-ID 209434-4
    ISSN 1873-2402 ; 0006-3223
    ISSN (online) 1873-2402
    ISSN 0006-3223
    DOI 10.1016/j.biopsych.2020.02.1178
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Connections With Connections: Dopaminergic Correlates of Neural Network Properties.

    Eisenberg, Daniel P / Berman, Karen F

    Biological psychiatry

    2019  Volume 85, Issue 5, Page(s) 366–367

    MeSH term(s) Dopamine ; Magnetic Resonance Imaging ; Magnetic Resonance Spectroscopy ; Neural Pathways ; Positron-Emission Tomography
    Chemical Substances Dopamine (VTD58H1Z2X)
    Language English
    Publishing date 2019-02-07
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Intramural ; Comment
    ZDB-ID 209434-4
    ISSN 1873-2402 ; 0006-3223
    ISSN (online) 1873-2402
    ISSN 0006-3223
    DOI 10.1016/j.biopsych.2019.01.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Ovarian hormones, genes, and the brain: the case of estradiol and the brain-derived neurotrophic factor (BDNF) gene.

    Wei, Shau-Ming / Berman, Karen F

    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

    2018  Volume 44, Issue 1, Page(s) 223–224

    MeSH term(s) Animals ; Brain/metabolism ; Brain-Derived Neurotrophic Factor/genetics ; Brain-Derived Neurotrophic Factor/metabolism ; Estradiol/metabolism ; Female ; Gene Expression Regulation ; Progesterone/metabolism
    Chemical Substances Brain-Derived Neurotrophic Factor ; Progesterone (4G7DS2Q64Y) ; Estradiol (4TI98Z838E)
    Language English
    Publishing date 2018-10-03
    Publishing country England
    Document type News ; Research Support, N.I.H., Intramural
    ZDB-ID 639471-1
    ISSN 1740-634X ; 0893-133X
    ISSN (online) 1740-634X
    ISSN 0893-133X
    DOI 10.1038/s41386-018-0223-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Subcortical Signatures of Hemizygosity and Psychosis in 22q11.2 Deletion Syndrome: Finding Common Ground in Rare Genetic Variation.

    Eisenberg, Daniel P / Gregory, Michael D / Berman, Karen F

    The American journal of psychiatry

    2020  Volume 177, Issue 7, Page(s) 564–566

    MeSH term(s) Arachnodactyly ; DiGeorge Syndrome ; Genetic Variation ; Humans ; Marfan Syndrome ; Psychotic Disorders
    Language English
    Publishing date 2020-06-18
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 280045-7
    ISSN 1535-7228 ; 0002-953X
    ISSN (online) 1535-7228
    ISSN 0002-953X
    DOI 10.1176/appi.ajp.2020.20050598
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Spatiotemporal Alterations in Working Memory-Related Beta Band Neuromagnetic Activity of Patients With Schizophrenia On and Off Antipsychotic Medication: Investigation With MEG.

    Rubinstein, Daniel Y / Eisenberg, Daniel P / Carver, Frederick W / Holroyd, Tom / Apud, Jose A / Coppola, Richard / Berman, Karen F

    Schizophrenia bulletin

    2023  Volume 49, Issue 3, Page(s) 669–678

    Abstract: Background and hypothesis: We used the uniquely high combined spatial and temporal resolution of magnetoencephalography to characterize working memory (WM)-related modulation of beta band activity in neuroleptic-free patients with schizophrenia in ... ...

    Abstract Background and hypothesis: We used the uniquely high combined spatial and temporal resolution of magnetoencephalography to characterize working memory (WM)-related modulation of beta band activity in neuroleptic-free patients with schizophrenia in comparison to a large sample of performance-matched healthy controls. We also tested for effects of antipsychotic medication on identified differences in these same patients.
    Study design: Inpatients with schizophrenia (n = 21) or psychotic disorder not otherwise specified (n = 4) completed N-back and control tasks during magnetoencephalography while on placebo and during antipsychotic medication treatment, in a blinded, randomized, counterbalanced manner. Healthy, performance-matched controls (N = 100) completed the same tasks. WM-related neural activation was estimated as beta band (14-30 Hz) desynchronization throughout the brain in successive 400 ms time windows. Voxel-wise statistical comparisons were performed between controls and patients while off-medication at each time window. Significant clusters resulting from this between-groups analysis were then used as regions-of-interest, the activations of which were compared between on- and off-medication conditions in patients.
    Study results: Controls showed beta-band desynchronization (activation) of a fronto-parietal network immediately preceding correct button press responses-the time associated with WM updating and task execution. Altered activation in medication-free patients occurred largely during this time, in prefrontal, parietal, and visual cortices. Medication altered patients' neural responses such that the activation time courses in these regions-of-interest more closely resembled those of controls.
    Conclusions: These findings demonstrate that WM-related beta band alterations in schizophrenia are time-specific and associated with neural systems targeted by antipsychotic medications. Future studies may investigate this association by examining its potential neurochemical basis.
    MeSH term(s) Humans ; Antipsychotic Agents/pharmacology ; Antipsychotic Agents/therapeutic use ; Schizophrenia/drug therapy ; Schizophrenia/complications ; Magnetoencephalography ; Memory, Short-Term/physiology ; Magnetic Resonance Imaging ; Neuropsychological Tests ; Brain Mapping
    Chemical Substances Antipsychotic Agents
    Language English
    Publishing date 2023-02-09
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Intramural
    ZDB-ID 439173-1
    ISSN 1745-1701 ; 0586-7614
    ISSN (online) 1745-1701
    ISSN 0586-7614
    DOI 10.1093/schbul/sbac178
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Altered pubertal timing in 7q11.23 copy number variations and associated genetic mechanisms.

    Wei, Shau-Ming / Gregory, Michael D / Nash, Tiffany / de Abreu E Gouvêa, Andrea / Mervis, Carolyn B / Cole, Katherine M / Garvey, Madeline H / Kippenhan, J Shane / Eisenberg, Daniel P / Kolachana, Bhaskar / Schmidt, Peter J / Berman, Karen F

    iScience

    2024  Volume 27, Issue 3, Page(s) 109113

    Abstract: Pubertal timing, including age at menarche (AAM), is a heritable trait linked to lifetime health outcomes. Here, we investigate genetic mechanisms underlying AAM by combining genome-wide association study (GWAS) data with investigations of two rare ... ...

    Abstract Pubertal timing, including age at menarche (AAM), is a heritable trait linked to lifetime health outcomes. Here, we investigate genetic mechanisms underlying AAM by combining genome-wide association study (GWAS) data with investigations of two rare genetic conditions clinically associated with altered AAM: Williams syndrome (WS), a 7q11.23 hemideletion characterized by early puberty; and duplication of the same genes (7q11.23 Duplication syndrome [Dup7]) characterized by delayed puberty. First, we confirm that AAM-derived polygenic scores in typically developing children (TD) explain a modest amount of variance in AAM (R
    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Journal Article
    ISSN 2589-0042
    ISSN (online) 2589-0042
    DOI 10.1016/j.isci.2024.109113
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  9. Article ; Online: Comparison of Transcranial Sonography and [

    Eisenberg, Daniel P / Lopez, Grisel / Gregory, Michael D / Berman, Karen F / Sidransky, Ellen

    Movement disorders : official journal of the Movement Disorder Society

    2021  Volume 37, Issue 3, Page(s) 629–634

    Abstract: Background: Mutations in GBA1 are a common genetic risk factor for parkinsonism; however, penetrance is incomplete, and biomarkers of future progression to parkinsonism are needed. Both nigral sonography and striatal [: Objective: The aim of this ... ...

    Abstract Background: Mutations in GBA1 are a common genetic risk factor for parkinsonism; however, penetrance is incomplete, and biomarkers of future progression to parkinsonism are needed. Both nigral sonography and striatal [
    Objective: The aim of this study is to evaluate the utility and coherence of these modalities in GBA1-associated parkinsonism.
    Methods: A total of 34 patients with GBA1 mutations (7 with parkinsonism) underwent both transcranial studies for substantia nigra echogenicity and [
    Results: Larger nigral echogenic areas and reduced striatal K
    Conclusions: Close correspondence between nigral echogenicity and striatal presynaptic dopamine synthesis capacity observed only in GBA1 carriers with parkinsonism provides validation that these two modalities may conjointly capture aspects of the biology underlying clinical parkinsonism but raises questions about their utility as predictive tools in at-risk subjects. © 2022 International Parkinson and Movement Disorder Society.
    MeSH term(s) Dihydroxyphenylalanine/analogs & derivatives ; Dopamine ; Glucosylceramidase/genetics ; Humans ; Mutation/genetics ; Parkinsonian Disorders/genetics ; Positron-Emission Tomography/methods ; Ultrasonography
    Chemical Substances fluorodopa F 18 (2C598205QX) ; Dihydroxyphenylalanine (63-84-3) ; GBA protein, human (EC 3.2.1.45) ; Glucosylceramidase (EC 3.2.1.45) ; Dopamine (VTD58H1Z2X)
    Language English
    Publishing date 2021-11-11
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Research Support, N.I.H., Intramural
    ZDB-ID 607633-6
    ISSN 1531-8257 ; 0885-3185
    ISSN (online) 1531-8257
    ISSN 0885-3185
    DOI 10.1002/mds.28852
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