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Article ; Online: Diabulimia and Type 1 Diabetes: An Unknown and Emerging Problem.

Rivolta, Benedetta / Masserini, Benedetta / Bernardi, Irene / Camera, Antonella / Liboà, Federico / Solerte, Sebastiano Bruno / Cerabolini, Chiara / Cerutti, Nadia

Endocrine, metabolic & immune disorders drug targets

2024

Abstract: Background: T1DM patients have a higher prevalence of eating disorders than the general population, and up to 30-40% of young T1DM patients suffer from an eating disorder, including diabulimia. Eating disorders worsen glycemic control and make insulin ... ...

Abstract	Background: T1DM patients have a higher prevalence of eating disorders than the general population, and up to 30-40% of young T1DM patients suffer from an eating disorder, including diabulimia. Eating disorders worsen glycemic control and make insulin therapy management more difficult. Closed loop systems (HCLS) allow major therapeutic flexibility; however, proper carbohydrate (CHO) counting remains a fundamental feature for insulin dose adjustments. Case report: A 30-year-old female patient affected by T1DM (with a past medical history of drug abuse and depressive syndrome) presented with inadequate glycemic control and prandial boli management. She started a CHO counting course and had a HCLS positioned, with progressive amelioration of glycemic control. During follow-up evaluations, HCLS data showed a progressive reduction and abeyance of prandial boli; the patient also developped an excessive fear of weight gain. An integrated approach between diabetologist, psychiatrist and dietitian allowed a diagnosis of diabulimia, an eating disorder characterized by a progressive reduction and elimination of carbohydrate ingestion and insulin boli, with episodes of uncontrolled binging and purging. A multidisciplinary approach (fortnightly dietetic and psychiatric evaluations, use of bioimpedance, fixed CHO content diet) allowed the patient to reach a better glycometabolic control and disease consciousness. Conclusion: T1DM patients need to pay great attention to food quality and quantity; hence, an eating disorder diagnosis may be challenging. Additionally, there are currently no standard screening methods for this purpose. In our experience, an integrated approach is fundamental and may be a valid strategy to face this emerging problem.
Language	English
Publishing date	2024-04-30
Publishing country	United Arab Emirates
Document type	Journal Article
ZDB-ID	2228325-0
ISSN	2212-3873 ; 1871-5303
ISSN (online)	2212-3873
ISSN	1871-5303
DOI	10.2174/0118715303314948240419060714
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Article ; Online: Smart Flow for the evaluation of the hemodialysis arteriovenous fistula.

Colucci, Marco / Torreggiani, Massimo / Bernardi, Irene / Stangalino, Simone / Catucci, Davide / Esposito, Vittoria / Sileno, Giuseppe / Esposito, Ciro

The journal of vascular access

2020 Volume 21, Issue 5, Page(s) 652–657

Abstract: Background: Smart Flow is an innovative tool available on the Carestream Touch Prime Ultrasound machines, which provides automated blood flow measurement and shows the vectors that form the blood flow in the vessel. We compared the use of Smart Flow ... ...

Abstract	Background: Smart Flow is an innovative tool available on the Carestream Touch Prime Ultrasound machines, which provides automated blood flow measurement and shows the vectors that form the blood flow in the vessel. We compared the use of Smart Flow with traditional Duplex Doppler Ultrasound to evaluate blood flow of arteriovenous fistulas in prevalent hemodialysis patients. Methods: A total of 31 chronic patients on hemodialysis were enrolled. Blood flow was measured on the brachial artery with Smart Flow and duplex Doppler ultrasound. In a subset of 26 patients, a video of the juxta-anastomotic efferent vein was recorded and analyzed to calculate an index of flow turbulence. Results: We enrolled 21 males and 10 females aged 68.52 ± 11.64 years at the time of evaluation with an average arteriovenous fistulas vintage of 50.23 ± 47.42 months and followed them up for 18.03 ± 5.18 months. Smart Flow and Duplex Doppler Ultrasound blood flow measurements positively correlated (p < 0.0001) in the same patient but Smart Flow gave higher blood flow values (995.0 vs 730.3 mL/min, p < 0.0001), and the Duplex Doppler Ultrasound blood flow standard deviation was similar to Smart Flow (125.4 vs 114.4 mL/min, p < 0.0001). The time needed to evaluate arteriovenous fistulas with Smart Flow was significantly shorter than Duplex Doppler Ultrasound (67.58 ± 19.89 vs 146.3 ± 26.35 s, p < 0.0001). No correlation was found between blood flow turbulence and the subsequent access failure. Conclusion: Smart Flow is reliable, reproducible, and faster than traditional duplex ultrasound. However, the additional information given by the Smart Flow technique does not seem to add any further benefits in terms of prediction of the access failure.
MeSH term(s)	Aged ; Aged, 80 and over ; Arteriovenous Shunt, Surgical/adverse effects ; Blood Flow Velocity ; Brachial Artery/diagnostic imaging ; Brachial Artery/physiopathology ; Brachial Artery/surgery ; Female ; Humans ; Image Interpretation, Computer-Assisted ; Male ; Middle Aged ; Predictive Value of Tests ; Prospective Studies ; Renal Dialysis ; Software ; Time Factors ; Treatment Outcome ; Ultrasonography, Doppler, Color ; Upper Extremity/blood supply ; Vascular Patency ; Veins/diagnostic imaging ; Veins/physiopathology ; Veins/surgery
Language	English
Publishing date	2020-01-02
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Video-Audio Media
ZDB-ID	2252820-9
ISSN	1724-6032 ; 1129-7298
ISSN (online)	1724-6032
ISSN	1129-7298
DOI	10.1177/1129729819897171
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Article ; Online: First Probe of Sub-GeV Dark Matter beyond the Cosmological Expectation with the COHERENT CsI Detector at the SNS.

Akimov, D / An, P / Awe, C / Barbeau, P S / Becker, B / Belov, V / Bernardi, I / Blackston, M A / Bock, C / Bolozdynya, A / Browning, J / Cabrera-Palmer, B / Chernyak, D / Conley, E / Daughhetee, J / Detwiler, J / Ding, K / Durand, M R / Efremenko, Y /

Elliott, S R / Fabris, L / Febbraro, M / Gallo Rosso, A / Galindo-Uribarri, A / Green, M P / Heath, M R / Hedges, S / Hoang, D / Hughes, M / Johnson, T / Khromov, A / Konovalov, A / Kozlova, E / Kumpan, A / Li, L / Link, J M / Liu, J / Mann, K / Markoff, D M / Mastroberti, J / Mueller, P E / Newby, J / Parno, D S / Penttila, S I / Pershey, D / Rapp, R / Raybern, J / Razuvaeva, O / Reyna, D / Rich, G C / Ross, J / Rudik, D / Runge, J / Salvat, D J / Salyapongse, A M / Sander, J / Scholberg, K / Shakirov, A / Simakov, G / Sinev, G / Snow, W M / Sosnovtsev, V / Suh, B / Tayloe, R / Tellez-Giron-Flores, K / Tolstukhin, I / Ujah, E / Vanderwerp, J / Varner, R L / Virtue, C J / Visser, G / Wongjirad, T / Yen, Y-R / Yoo, J / Yu, C-H / Zettlemoyer, J

Physical review letters

2023 Volume 130, Issue 5, Page(s) 51803

Abstract: The COHERENT Collaboration searched for scalar dark matter particles produced at the Spallation Neutron Source with masses between 1 and 220 MeV/c^{2} using a CsI[Na] scintillation detector sensitive to nuclear recoils above 9 keV_{nr}. No evidence for ...

Abstract	The COHERENT Collaboration searched for scalar dark matter particles produced at the Spallation Neutron Source with masses between 1 and 220 MeV/c^{2} using a CsI[Na] scintillation detector sensitive to nuclear recoils above 9 keV_{nr}. No evidence for dark matter is found and we thus place limits on allowed parameter space. With this low-threshold detector, we are sensitive to coherent elastic scattering between dark matter and nuclei. The cross section for this process is orders of magnitude higher than for other processes historically used for accelerator-based direct-detection searches so that our small, 14.6 kg detector significantly improves on past constraints. At peak sensitivity, we reject the flux consistent with the cosmologically observed dark-matter concentration for all coupling constants α_{D}<0.64, assuming a scalar dark-matter particle. We also calculate the sensitivity of future COHERENT detectors to dark-matter signals which will ambitiously test multiple dark-matter spin scenarios.
Language	English
Publishing date	2023-02-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.130.051803
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Article ; Online: The role of MDCT arthrography in the follow-up of scapholunate stabilisation.

Genovese, Eugenio / Spanò, Emanuela / Mariani, Davide / De Bernardi, Irene / Pilato, Giorgio / Fugazzola, Carlo

La Radiologia medica

2013 Volume 118, Issue 7, Page(s) 1157–1170

Abstract: Purpose: The aim of this study was to assess outcomes in a group of patients with scapholunate dissociation treated with stabilisation surgery (Brunelli-Stanley) and to compare arthrography with multidetector computed tomography (MDCT) with conventional ...

Abstract	Purpose: The aim of this study was to assess outcomes in a group of patients with scapholunate dissociation treated with stabilisation surgery (Brunelli-Stanley) and to compare arthrography with multidetector computed tomography (MDCT) with conventional radiography, the gold standard in the follow-up of wrist surgery. Materials and methods: Twelve patients (13 wrists) underwent surgery for scapholunate dissociation and were followed up with clinical (visual analogue scale, Mayo Wrist Score, Patient-Rated Wrist Evaluation, and Disabilities of the Arm, Shoulder, and Hand) and radiological assessment (conventional radiography and CT arthrography). Conventional radiography was assessed for: the scapholunate gap, scapholunate angle, radiolunate angle, capitate-lunate angle, and carpal height index; the CT arthrography images were also evaluated for: the distance between the dorsal exit hole of the bone tunnel and the proximal scaphoid pole, the thickness and tension of the flexor carpi radialis (FCR) strip, and any signs of joint degeneration. Results: Analysis of the data from conventional radiography and MDCT arthrography demonstrated a significant statistical correlation among the measurements obtained on the radiograms and multiplanar CT reconstructions and the patients' clinical outcome. Conclusions: Our results show that MDCT arthrography has the same value as conventional radiography in the evaluation of standard parameters (scapholunate gap, scapholunate angle, radiolunate angle, capitolunate angle, carpal height index), but in addition provides an accurate delineation of the FCR tendon graft, allowing differentiation of its thickness, direction and degree of tension.
MeSH term(s)	Adult ; Arthrography/methods ; Casts, Surgical ; Disability Evaluation ; Female ; Humans ; Joint Instability/diagnostic imaging ; Joint Instability/surgery ; Lunate Bone/diagnostic imaging ; Lunate Bone/surgery ; Male ; Middle Aged ; Multidetector Computed Tomography ; Pain Measurement ; Scaphoid Bone/diagnostic imaging ; Scaphoid Bone/surgery ; Treatment Outcome ; Wrist Joint/diagnostic imaging ; Wrist Joint/surgery
Language	English
Publishing date	2013-06-25
Publishing country	Italy
Document type	Journal Article
ZDB-ID	205751-7
ISSN	1826-6983 ; 0033-8362
ISSN (online)	1826-6983
ISSN	0033-8362
DOI	10.1007/s11547-013-0949-4
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Article ; Online: Mammalia, Chiroptera, Molossidae, Molossops neglectus

Gazarini, J. / Bernardi, I. P.

Check List, Vol 3, Iss 2, Pp 123-

First record in the State of Paraná, Brazil.

2007 Volume 125

Keywords	Biology (General) ; QH301-705.5
Language	English
Publishing date	2007-01-01T00:00:00Z
Publisher	Pensoft Publishers
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Microwave ablation therapy for treating primary and secondary lung tumours: technical note.

Carrafiello, G / Mangini, M / De Bernardi, I / Fontana, F / Dionigi, G / Cuffari, S / Imperatori, A / Laganà, D / Fugazzola, C

La Radiologia medica

2010 Volume 115, Issue 6, Page(s) 962–974

Abstract: Purpose: The purpose of our study was to retrospectively evaluate the feasibility, safety and effectiveness of microwave ablation (MWA) in nine patients with unresectable lung tumour.: Materials and methods: Ten lesions were treated in ten ablation ... ...

Abstract	Purpose: The purpose of our study was to retrospectively evaluate the feasibility, safety and effectiveness of microwave ablation (MWA) in nine patients with unresectable lung tumour. Materials and methods: Ten lesions were treated in ten ablation sessions in nine patients. The treatments were performed with a microwave generator with 45 W and 915 MHz connected to a 14.5-gauge antenna for 10 min. Antenna placement was performed with computed tomography (CT) fluoroscopy guidance or XperGuide. All patients underwent CT follow-up at 1, 3 and 6 months from the procedure. Results: Technical success was obtained in all cases; mortality at 30 days was 0%. Conclusions: This study shows that in selected patients, MWA is a valid alternative to other ablative techniques. Further studies are required to demonstrate the short- and long-term effects of this technique and to make a comparison with other available ablation systems, especially with radiofrequency.
MeSH term(s)	Aged ; Aged, 80 and over ; Catheter Ablation/adverse effects ; Catheter Ablation/methods ; Feasibility Studies ; Female ; Humans ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/pathology ; Lung Neoplasms/secondary ; Lung Neoplasms/surgery ; Male ; Microwaves/adverse effects ; Microwaves/therapeutic use ; Neoplasm Metastasis ; Retrospective Studies ; Tomography, X-Ray Computed ; Treatment Outcome
Language	Italian
Publishing date	2010-03-29
Publishing country	Italy
Document type	Journal Article
ZDB-ID	205751-7
ISSN	1826-6983 ; 0033-8362
ISSN (online)	1826-6983
ISSN	0033-8362
DOI	10.1007/s11547-010-0547-7
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Article ; Online: Measurement of the Coherent Elastic Neutrino-Nucleus Scattering Cross Section on CsI by COHERENT.

Elliott, S R / Fabris, L / Febbraro, M / Gallo Rosso, A / Galindo-Uribarri, A / Green, M P / Heath, M R / Hedges, S / Hoang, D / Hughes, M / Johnson, T / Khromov, A / Konovalov, A / Kozlova, E / Kumpan, A / Li, L / Link, J M / Liu, J / Mann, K / Markoff, D M / Mastroberti, J / Mueller, P E / Newby, J / Parno, D S / Penttila, S I / Pershey, D / Rapp, R / Ray, H / Raybern, J / Razuvaeva, O / Reyna, D / Rich, G C / Ross, J / Rudik, D / Runge, J / Salvat, D J / Salyapongse, A M / Scholberg, K / Shakirov, A / Simakov, G / Sinev, G / Snow, W M / Sosnovstsev, V / Suh, B / Tayloe, R / Tellez-Giron-Flores, K / Tolstukhin, I / Ujah, E / Vanderwerp, J / Varner, R L / Virtue, C J / Visser, G / Wongjirad, T / Yen, Y-R / Yoo, J / Yu, C-H / Zettlemoyer, J

Physical review letters

2022 Volume 129, Issue 8, Page(s) 81801

Abstract: We measured the cross section of coherent elastic neutrino-nucleus scattering (CEvNS) using a CsI[Na] scintillating crystal in a high flux of neutrinos produced at the Spallation Neutron Source at Oak Ridge National Laboratory. New data collected before ... ...

Abstract	We measured the cross section of coherent elastic neutrino-nucleus scattering (CEvNS) using a CsI[Na] scintillating crystal in a high flux of neutrinos produced at the Spallation Neutron Source at Oak Ridge National Laboratory. New data collected before detector decommissioning have more than doubled the dataset since the first observation of CEvNS, achieved with this detector. Systematic uncertainties have also been reduced with an updated quenching model, allowing for improved precision. With these analysis improvements, the COHERENT Collaboration determined the cross section to be (165_{-25}^{+30})×10^{-40} cm^{2}, consistent with the standard model, giving the most precise measurement of CEvNS yet. The timing structure of the neutrino beam has been exploited to compare the CEvNS cross section from scattering of different neutrino flavors. This result places leading constraints on neutrino nonstandard interactions while testing lepton flavor universality and measures the weak mixing angle as sin^{2}θ_{W}=0.220_{-0.026}^{+0.028} at Q^{2}≈(50 MeV)^{2}.
Language	English
Publishing date	2022-05-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.129.081801
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Article ; Online: Measurement of Electron-Neutrino Charged-Current Cross Sections on ^{127}I with the COHERENT NaIνE Detector.

An, P / Awe, C / Barbeau, P S / Becker, B / Belov, V / Bernardi, I / Bock, C / Bolozdynya, A / Bouabid, R / Brown, A / Browning, J / Cabrera-Palmer, B / Cervantes, M / Conley, E / Daughhetee, J / Detwiler, J / Ding, K / Durand, M R / Efremenko, Y /

Elliott, S R / Fabris, L / Febbraro, M / Gallo Rosso, A / Galindo-Uribarri, A / Germer, A C / Green, M P / Hakenmüller, J / Heath, M R / Hedges, S / Hughes, M / Johnson, B A / Johnson, T / Khromov, A / Konovalov, A / Kozlova, E / Kumpan, A / Kyzylova, O / Li, L / Link, J M / Liu, J / Mahoney, M / Major, A / Mann, K / Markoff, D M / Mastroberti, J / Mattingly, J / Mueller, P E / Newby, J / Parno, D S / Penttila, S I / Pershey, D / Prior, C G / Rapp, R / Ray, H / Raybern, J / Razuvaeva, O / Reyna, D / Rich, G C / Ross, J / Rudik, D / Runge, J / Salvat, D J / Sander, J / Scholberg, K / Shakirov, A / Simakov, G / Sinev, G / Skuse, C / Snow, W M / Sosnovtsev, V / Subedi, T / Suh, B / Tayloe, R / Tellez-Giron-Flores, K / Tsai, Y-T / Ujah, E / Vanderwerp, J / van Nieuwenhuizen, E E / Varner, R L / Virtue, C J / Visser, G / Walkup, K / Ward, E M / Wongjirad, T / Yoo, J / Yu, C-H / Zawada, A / Zettlemoyer, J / Zderic, A

Physical review letters

2023 Volume 131, Issue 22, Page(s) 221801

Abstract: Using an 185-kg NaI[Tl] array, COHERENT has measured the inclusive electron-neutrino charged-current cross section on ^{127}I with pion decay-at-rest neutrinos produced by the Spallation Neutron Source at Oak Ridge National Laboratory. Iodine is one the ... ...

Abstract	Using an 185-kg NaI[Tl] array, COHERENT has measured the inclusive electron-neutrino charged-current cross section on ^{127}I with pion decay-at-rest neutrinos produced by the Spallation Neutron Source at Oak Ridge National Laboratory. Iodine is one the heaviest targets for which low-energy (≤50 MeV) inelastic neutrino-nucleus processes have been measured, and this is the first measurement of its inclusive cross section. After a five-year detector exposure, COHERENT reports a flux-averaged cross section for electron neutrinos of 9.2_{-1.8}^{+2.1}×10^{-40} cm^{2}. This corresponds to a value that is ∼41% lower than predicted using the MARLEY event generator with a measured Gamow-Teller strength distribution. In addition, the observed visible spectrum from charged-current scattering on ^{127}I has been measured between 10 and 55 MeV, and the exclusive zero-neutron and one-or-more-neutron emission cross sections are measured to be 5.2_{-3.1}^{+3.4}×10^{-40} and 2.2_{-0.5}^{+0.4}×10^{-40} cm^{2}, respectively.
Language	English
Publishing date	2023-12-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.131.221801
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Article: Advanced Oxidation Processes at Laboratory Scale: Environmental and Economic Impacts

GimeÌnez, Jaime / Bayarri BernardiÌ / Esplugas Santiago / GonzaÌlez OÌscar / Malato Sixto / Peral JoseÌ

ACS sustainable chemistry . 2015 Dec. 07, v. 3, no. 12

2015

Abstract: Advanced Oxidation Processes (AOPs) are widely used at laboratory scale in the treatment of different pollutants, and many references appear in the literature on this subject. However, there are not many works devoted to the study of the impact of these ... ...

Abstract	Advanced Oxidation Processes (AOPs) are widely used at laboratory scale in the treatment of different pollutants, and many references appear in the literature on this subject. However, there are not many works devoted to the study of the impact of these laboratory works from an environmental and economic point of view. For these reasons, this study is focused on the environmental impact evaluation, by LCA, of two AOPs (photocatalysis and pho-Fenton) in two different experimental setups (solarbox and CPCs), for the treatment of metoprolol. LCA has proved to be useful to compare the AOPs and the tested devices. In the same way, an economic assessment was made for the same AOPs and installations. Conclusions are very meaningful, pointing out that the cost of such experiments at laboratory level is not negligible and has to be seriously considered. As a consequence, laboratory work has to be accurately planned, and analysis techniques and proofs to be used must be carefully selected to avoid excessive increases in the costs of laboratory experiments.
Keywords	economic analysis ; economic impact ; environmental impact ; laboratory experimentation ; life cycle assessment ; oxidation ; photocatalysis ; pollutants
Language	English
Dates of publication	2015-1207
Size	p. 3188-3196.
Publishing place	American Chemical Society
Document type	Article
ISSN	2168-0485
DOI	10.1021/acssuschemeng.5b00778
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Microwave ablation of renal tumors: state of the art and development trends.

Floridi, Chiara / De Bernardi, Irene / Fontana, Federico / Muollo, Alessandra / Ierardi, Anna Maria / Agostini, Andrea / Fonio, Paolo / Squillaci, Ettore / Brunese, Luca / Fugazzola, Carlo / Carrafiello, Gianpaolo

La Radiologia medica

2014 Volume 119, Issue 7, Page(s) 533–540

Abstract: In the last decades an increased incidence of new renal tumor cases has been for clinically localized, small tumors <2.0 cm. This trend for small, low-stage tumors is the reflection of earlier diagnosis primarily as a result of the widespread and ... ...

Abstract	In the last decades an increased incidence of new renal tumor cases has been for clinically localized, small tumors <2.0 cm. This trend for small, low-stage tumors is the reflection of earlier diagnosis primarily as a result of the widespread and increasing use of non-invasive abdominal imaging modalities such as ultrasound, computerized tomography, and magnetic resonance imaging. Renal tumors are often diagnosed in elderly patients, with medical comorbidities whom the risk of surgical complications may pose a greater risk of death than that due to the tumor itself. In these patients, unsuitable for surgical approach, thermal ablation represents a valid alternative to traditional surgery. Thermal ablation is a less invasive, less morbid treatment option thanks to reduced blood loss, lower incidence of complications during the procedure and a less long convalescence. At present, the most widely used thermal ablative techniques are cryoablation, radiofrequency ablation and microwave ablation (MWA). MWA offers many benefits of other ablation techniques and offers several other advantages: higher intratumoral temperatures, larger tumor ablation volumes, faster ablation times, the ability to use multiple applicators simultaneously, optimal heating of cystic masses and tumors close to the vessels and less procedural pain. This review aims to provide the reader with an overview about the state of the art of microwave ablation for renal tumors and to cast a glance on the new development trends of this technique.
MeSH term(s)	Ablation Techniques/trends ; Diagnostic Imaging ; Humans ; Kidney Neoplasms/diagnosis ; Kidney Neoplasms/pathology ; Kidney Neoplasms/surgery ; Microwaves/therapeutic use ; Neoplasm Staging ; Radiography, Interventional ; Ultrasonography, Interventional
Keywords	covid19
Language	English
Publishing date	2014-07-08
Publishing country	Italy
Document type	Journal Article ; Review
ZDB-ID	205751-7
ISSN	1826-6983 ; 0033-8362
ISSN (online)	1826-6983
ISSN	0033-8362
DOI	10.1007/s11547-014-0426-8
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