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  1. Article ; Online: Endothelial caveolin and its scaffolding domain in cancer.

    Bernatchez, Pascal

    Cancer metastasis reviews

    2020  Volume 39, Issue 2, Page(s) 471–483

    Abstract: Since the initial reports implicating caveolin-1 (CAV1) in neoplasia, the scientific community has made tremendous strides towards understanding how CAV1-dependent signaling and caveolae assembly modulate solid tumor growth. Once a solid neoplastic tumor ...

    Abstract Since the initial reports implicating caveolin-1 (CAV1) in neoplasia, the scientific community has made tremendous strides towards understanding how CAV1-dependent signaling and caveolae assembly modulate solid tumor growth. Once a solid neoplastic tumor reaches a certain size, it will increasingly rely on its stroma to meet the metabolic demands of the rapidly proliferating cancer cells, a limitation typically but not exclusively addressed via the formation of new blood vessels. Landmark studies using xenograft tumor models have highlighted the importance of stromal CAV1 during neoplastic blood vessel growth from preexisting vasculature, a process called angiogenesis, and helped identify endothelium-specific signaling events regulated by CAV1, such as vascular endothelial growth factor (VEGF) receptors as well as the endothelial nitric oxide (NO) synthase (eNOS) systems. This chapter provides a glimpse into the signaling events modulated by CAV1 and its scaffolding domain (CSD) during endothelial-specific aspects of neoplastic growth, such as vascular permeability, angiogenesis, and mechanotransduction.
    MeSH term(s) Animals ; Caveolin 1/metabolism ; Endothelium, Vascular/metabolism ; Endothelium, Vascular/pathology ; Humans ; Neoplasms/blood supply ; Neoplasms/metabolism ; Neoplasms/pathology ; Neovascularization, Pathologic/metabolism ; Neovascularization, Pathologic/pathology ; Signal Transduction ; Stromal Cells/metabolism ; Stromal Cells/pathology
    Chemical Substances Caveolin 1
    Language English
    Publishing date 2020-05-29
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 604857-2
    ISSN 1573-7233 ; 0167-7659
    ISSN (online) 1573-7233
    ISSN 0167-7659
    DOI 10.1007/s10555-020-09895-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Scaffolds and the scaffolding domain: an alternative paradigm for caveolin-1 signaling.

    Lim, John E / Bernatchez, Pascal / Nabi, Ivan R

    Biochemical Society transactions

    2024  Volume 52, Issue 2, Page(s) 947–959

    Abstract: Caveolin-1 (Cav1) is a 22 kDa intracellular protein that is the main protein constituent of bulb-shaped membrane invaginations known as caveolae. Cav1 can be also found in functional non-caveolar structures at the plasma membrane called scaffolds. ... ...

    Abstract Caveolin-1 (Cav1) is a 22 kDa intracellular protein that is the main protein constituent of bulb-shaped membrane invaginations known as caveolae. Cav1 can be also found in functional non-caveolar structures at the plasma membrane called scaffolds. Scaffolds were originally described as SDS-resistant oligomers composed of 10-15 Cav1 monomers observable as 8S complexes by sucrose velocity gradient centrifugation. Recently, cryoelectron microscopy (cryoEM) and super-resolution microscopy have shown that 8S complexes are interlocking structures composed of 11 Cav1 monomers each, which further assemble modularly to form higher-order scaffolds and caveolae. In addition, Cav1 can act as a critical signaling regulator capable of direct interactions with multiple client proteins, in particular, the endothelial nitric oxide (NO) synthase (eNOS), a role believed by many to be attributable to the highly conserved and versatile scaffolding domain (CSD). However, as the CSD is a hydrophobic domain located by cryoEM to the periphery of the 8S complex, it is predicted to be enmeshed in membrane lipids. This has led some to challenge its ability to interact directly with client proteins and argue that it impacts signaling only indirectly via local alteration of membrane lipids. Here, based on recent advances in our understanding of higher-order Cav1 structure formation, we discuss how the Cav1 CSD may function through both lipid and protein interaction and propose an alternate view in which structural modifications to Cav1 oligomers may impact exposure of the CSD to cytoplasmic client proteins, such as eNOS.
    MeSH term(s) Caveolin 1/metabolism ; Caveolin 1/chemistry ; Humans ; Signal Transduction ; Animals ; Nitric Oxide Synthase Type III/metabolism ; Caveolae/metabolism ; Cryoelectron Microscopy ; Protein Domains ; Cell Membrane/metabolism
    Chemical Substances Caveolin 1 ; Nitric Oxide Synthase Type III (EC 1.14.13.39)
    Language English
    Publishing date 2024-04-16
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 184237-7
    ISSN 1470-8752 ; 0300-5127
    ISSN (online) 1470-8752
    ISSN 0300-5127
    DOI 10.1042/BST20231570
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Humanization of the mdx Mouse Phenotype for Duchenne Muscular Dystrophy Modeling: A Metabolic Perspective.

    Donen, Graham / Milad, Nadia / Bernatchez, Pascal

    Journal of neuromuscular diseases

    2023  Volume 10, Issue 6, Page(s) 1003–1012

    Abstract: Duchenne muscular dystrophy (DMD) is a severe form of muscular dystrophy (MD) that is characterized by early muscle wasting and lethal cardiorespiratory failure. While the mdx mouse is the most common model of DMD, it fails to replicate the severe loss ... ...

    Abstract Duchenne muscular dystrophy (DMD) is a severe form of muscular dystrophy (MD) that is characterized by early muscle wasting and lethal cardiorespiratory failure. While the mdx mouse is the most common model of DMD, it fails to replicate the severe loss of muscle mass and other complications observed in patients, in part due to the multiple rescue pathways found in mice. This led to several attempts at improving DMD animal models by interfering with these rescue pathways through double transgenic approaches, resulting in more severe phenotypes with mixed relevance to the human pathology. As a growing body of literature depicts DMD as a multi-system metabolic disease, improvements in mdx-based modeling of DMD may be achieved by modulating whole-body metabolism instead of muscle homeostasis. This review provides an overview of the established dual-transgenic approaches that exacerbate the mild mdx phenotype by primarily interfering with muscle homeostasis and highlights how advances in DMD modeling coincide with inducing whole-body metabolic changes. We focus on the DBA2/J strain-based D2.mdx mouse with heightened transforming growth factor (TGF)-β signaling and the dyslipidemic mdx/apolipoprotein E (mdx/ApoE) knock-out (KO) mouse, and summarize how these novel models emulate the metabolic changes observed in DMD.
    MeSH term(s) Humans ; Animals ; Mice ; Muscular Dystrophy, Duchenne/metabolism ; Mice, Inbred mdx ; Muscle, Skeletal/pathology ; Mice, Inbred C57BL ; Phenotype
    Language English
    Publishing date 2023-08-13
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2214-3602
    ISSN (online) 2214-3602
    DOI 10.3233/JND-230126
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A need to better monitor the effects of coastal defence measures on coastal socio-ecological systems to improve future adaptation solutions

    Sauvé, Philippe / Bernatchez, Pascal / Moisset, Sophie / Glaus, Mathias / Goudreault, Marc-Olivier

    Ocean and Coastal Management. 2023 May, v. 239 p.106599-

    2023  

    Abstract: Decision-making in a coastal socio-ecological system involves managing a site-specific complexity arising not only from the interaction between hydrodynamic and morphological conditions, but also from the interactions between human structures and ... ...

    Abstract Decision-making in a coastal socio-ecological system involves managing a site-specific complexity arising not only from the interaction between hydrodynamic and morphological conditions, but also from the interactions between human structures and ecological systems, as well as the conflicting needs and interests of local actors. In addition, the projections of climate change impacts on coastal systems have a degree of uncertainty, which increases the general unpredictability of coastal dynamic behaviour, and adds a layer of complexity to the decision-making process. Scientific knowledge can help reduce some of the inherent uncertainties, and is essential when it comes to making sound decisions on the choice of appropriate coastal defence measures (CDMs) that are adapted to specific coastal environments and improve the resilience of coastal communities. This paper is based on a meta-analysis of 355 CDMs case studies drawn from 301 publications. From these published case studies, the objectives were to analyze the geographical and physical contexts in which CDMs monitoring was carried out and, based on the findings, to recommend areas of improvement necessary to help make sound decisions in any type of coastal environment. The meta-analysis showed that study sites are not evenly distributed around the world. Most originate from Europe (n = 106), the USA (n = 151) and Australia (n = 30), while few studies have been carried out in Africa and Asia where dense population resides in high-risk zones. Also noticeable is the absence of sites in high latitude climates where ice plays a major role in the erosion process. Five basic variables (coastal type, sediment type, wave characteristics, tidal range, and currents or sediment transport characteristics) are used in publications to characterize study sites according to their physical components. However, only 13 of the 355 sites included a complete characterization using the 5 variables, of which coastal and sediment types are the most frequently identified (77.2% and 72.7% respectively). In general, CDMs are studied in the context of unconsolidated low shore (59.4%) and in sandy environments (74.6%). Information on tidal range, wave climate, and currents, or sediment transport characteristics, is much scarcer. Since 1990, 3 of the 10 CDMs identified in the studies have received more attention than the others; these are beach nourishments, seawalls and breakwaters, with respective cumulative study sites of 164, 67 and 50. The geomorphological effects of CDMs are the most studied (55.1%), followed by ecological (31.2%), hydrodynamic (9.1%), and social (4.6%). Overall, this meta-analysis helped identify knowledge gaps regarding geographical and physical contexts in which CDMs monitoring was held. It also gave an indication of the kind of improvement necessary for global-scale adaptation planning, and for a better decision-making process to reduce coastal risks in the most vulnerable coastal communities. Finally, the analysis shows that 4.4% of the studies on defence measures include monitoring of their effects on the coastal zone. A conceptual scheme is proposed for the evaluation of adaptation solutions based on the global monitoring of coastal zones to measure coastal change trajectories in the context of climate change.
    Keywords climate ; climate change ; coastal zone management ; coasts ; decision making ; humans ; hydrodynamics ; ice ; latitude ; meta-analysis ; sediment transport ; sediments ; social environment ; uncertainty ; Africa ; Asia ; Australia ; Europe ; Coastal engineering ; Coastal protection ; Coastal defence measures ; Decision-making ; Coastal erosion ; Integrated coastal zone management ; Monitoring for coastal adaptation
    Language English
    Dates of publication 2023-05
    Publishing place Elsevier Ltd
    Document type Article ; Online
    ISSN 0964-5691
    DOI 10.1016/j.ocecoaman.2023.106599
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Nitric oxide in the Marfan vasculature: Friend or foe?

    Tehrani, Arash Y / Ciufolini, Marco A / Bernatchez, Pascal

    Nitric oxide : biology and chemistry

    2021  Volume 116, Page(s) 27–34

    Abstract: Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the FBN1 gene, which encodes fibrillin-1, a protein essential for the formation and stabilization of elastic fibers as well as signaling homeostasis. Progressive aortic root ... ...

    Abstract Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the FBN1 gene, which encodes fibrillin-1, a protein essential for the formation and stabilization of elastic fibers as well as signaling homeostasis. Progressive aortic root widening is the most serious manifestation of MFS as it can lead to aortic dissection, aneurysm formation and rupture. However, despite their ability to decrease the hemodynamic stress the aorta is subjected to, anti-hypertensive medications often lead to underwhelming reductions in the rate of aortic root dilation, which illustrates how fragmental our understanding of MFS-associated aortic remodeling is. This manuscript summarizes recent evidence that document nitric oxide (NO) synthase (NOS)-related changes to the vasculature during the pathogenesis of MFS and how they result in a unique state of vascular dysfunction that likely plays a causal role in the aortic root widening process. We also review how clinic-approved and experimental therapies as well lifestyle approaches may promote aortic root stability by correcting NO homeostasis, which if properly optimized may improve outcomes in this population afflicted by a notoriously refractory type of aortopathy.
    MeSH term(s) Animals ; Aorta/metabolism ; Aortic Aneurysm/etiology ; Endothelium, Vascular/metabolism ; Humans ; Marfan Syndrome/complications ; Marfan Syndrome/metabolism ; Nitric Oxide/metabolism ; Nitric Oxide Synthase Type II/metabolism ; Nitric Oxide Synthase Type III/metabolism
    Chemical Substances Nitric Oxide (31C4KY9ESH) ; Nitric Oxide Synthase Type II (EC 1.14.13.39) ; Nitric Oxide Synthase Type III (EC 1.14.13.39)
    Language English
    Publishing date 2021-08-31
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1362794-6
    ISSN 1089-8611 ; 1089-8603
    ISSN (online) 1089-8611
    ISSN 1089-8603
    DOI 10.1016/j.niox.2021.08.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Heterogenous improvements in endothelial function by sub-blood pressure lowering doses of ARBs result in major anti-aortic root remodeling effects.

    Tehrani, Arash Y / Zhao, Roy / Donen, Graham / Bernatchez, Pascal

    Nitric oxide : biology and chemistry

    2022  Volume 131, Page(s) 18–25

    Abstract: Low basal nitric oxide (NO) production is associated with a dysfunctional endothelium and vascular diseases. We have shown that some angiotensin II (AngII) receptor type 1 (AT1R) blockers (ARBs), a group of clinic-approved blood pressure (BP)-lowering ... ...

    Abstract Low basal nitric oxide (NO) production is associated with a dysfunctional endothelium and vascular diseases. We have shown that some angiotensin II (AngII) receptor type 1 (AT1R) blockers (ARBs), a group of clinic-approved blood pressure (BP)-lowering medications, are also capable of activating endothelial function acutely and chronically, both ex vivo and in vivo, in pleiotropic, AngII-independent fashions, which suggested that endothelial function enhancement with ARBs may be independent of their well-documented BP lowering properties. Herein, we attempt to identify the most potent ARB at activating endothelial function when administered at sub-BP-lowering doses and determine its anti-aortic root remodeling properties in a model of Marfan syndrome (MFS). Amongst the 8 clinically available ARBs tested, only telmisartan and azilsartan induced significant (70% and 49%, respectively) NO-dependent inhibition of aortic contractility when administered for 4 weeks at sub-BP lowering, EC
    MeSH term(s) Humans ; Telmisartan/pharmacology ; Telmisartan/therapeutic use ; Blood Pressure ; Angiotensin Receptor Antagonists/pharmacology ; Angiotensin Receptor Antagonists/therapeutic use ; Angiotensin II Type 1 Receptor Blockers/pharmacology ; Angiotensin-Converting Enzyme Inhibitors/pharmacology ; Marfan Syndrome ; Endothelium ; Benzoates/pharmacology ; Hypertension/drug therapy
    Chemical Substances Telmisartan (U5SYW473RQ) ; Angiotensin Receptor Antagonists ; Angiotensin II Type 1 Receptor Blockers ; Angiotensin-Converting Enzyme Inhibitors ; Benzoates
    Language English
    Publishing date 2022-12-21
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1362794-6
    ISSN 1089-8611 ; 1089-8603
    ISSN (online) 1089-8611
    ISSN 1089-8603
    DOI 10.1016/j.niox.2022.12.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Dyslipidemia in Muscular Dystrophy: A Systematic Review and Meta-Analysis.

    Sun, Zeren / Wang, Xindi / White, Zoe / Dormuth, Colin / Morales, Fernando / Bernatchez, Pascal

    Journal of neuromuscular diseases

    2023  Volume 10, Issue 4, Page(s) 505–516

    Abstract: Background: Muscular dystrophies (MDs) are characterized by chronic muscle wasting but also poorly understood metabolic co-morbidities. We have recently shown that Duchenne MD (DMD) patients, dogs and asymptomatic carriers are affected by a new form of ... ...

    Abstract Background: Muscular dystrophies (MDs) are characterized by chronic muscle wasting but also poorly understood metabolic co-morbidities. We have recently shown that Duchenne MD (DMD) patients, dogs and asymptomatic carriers are affected by a new form of dyslipidemia that may exacerbate muscle damage.
    Objective: We aimed to perform a systematic review and meta-analysis for evidence that other types of MDs are associated with dyslipidemia compared to healthy controls.
    Methods: Search was conducted using MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials for reports that compare plasma/serum lipids from MD patients and controls, and meta-analysis of cross-sectional studies quantifying total cholesterol, high-density lipoprotein, low density lipoprotein and triglycerides was performed.
    Results: Out of 749 studies, 17 met our inclusion criteria for meta-analysis. 14 of the 17 studies (82%) included investigated myotonic dystrophy (DM); other studies were on pseudohypertrophic MD (PMD) or DMD. As a whole, MD individuals had significantly higher levels of circulating total cholesterol (Hedges' g with 95% confidence interval [CI], 0.80 [0.03 - 1.56]; p = 0.04) and triglycerides (Hedges' g with 95% confidence interval [CI], 2.28[0.63 - 3.92]; p = 0.01) compared to controls. Meta-regression analysis showed the percentage of male gender was significantly associated with the difference in total cholesterol (beta = 0.05; 95% CI, - 0.02 to 0.11; p = 0.043) and high-density lipoprotein (beta = - 9.38; 95% CI, - 16.26 to - 2.50; p = 0.028).
    Conclusions: MD is associated with significantly higher circulating levels of total cholesterol and triglycerides. However, caution on the interpretation of these findings is warranted and future longitudinal research is required to better understand this relationship.
    MeSH term(s) Male ; Cholesterol ; Cross-Sectional Studies ; Dyslipidemias ; Lipoproteins, HDL ; Muscular Dystrophies ; Triglycerides ; Female ; Humans
    Chemical Substances Cholesterol (97C5T2UQ7J) ; Lipoproteins, HDL ; Triglycerides
    Language English
    Publishing date 2023-05-12
    Publishing country Netherlands
    Document type Meta-Analysis ; Systematic Review
    ISSN 2214-3602
    ISSN (online) 2214-3602
    DOI 10.3233/JND-230064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Not just an engineering problem: The role of knowledge and understanding of ecosystem services for adaptive management of coastal erosion

    Jacob, Céline / Bernatchez, Pascal / Dupras, Jérôme / Cusson, Mathieu

    Ecosystem services. 2021 Oct., v. 51

    2021  

    Abstract: Coastal ecosystems are recognized as important providers of ecosystem services such as carbon storage, increased fish productivity, and wave energy reduction. In a context of climate change, coastal ecosystems are exposed to erosion and subject to ... ...

    Abstract Coastal ecosystems are recognized as important providers of ecosystem services such as carbon storage, increased fish productivity, and wave energy reduction. In a context of climate change, coastal ecosystems are exposed to erosion and subject to coastal squeeze, even as they provide natural coastal protection against extreme weather. While civil engineering solutions often take centre stage in mitigating coastal erosion and protecting infrastructure from storms and sea level rise, we seek to explore the social dimension of adaptive management of socio-ecological systems and more specifically the role of knowledge and learning. Using an ecosystem services (ES) framework, we provide a first evaluation of local stakeholders’ perceptions of coastal habitats in maritime Quebec. The findings demonstrate the importance of a social approach for coastal ES valuation, in particular in addressing the complex question of cultural ES. A better understanding of the links between coastal stakeholders and their natural environment can help decision-makers and practitioners design conservation management and coastal adaptation measures mainstreaming the role of coastal habitats. Nevertheless, a change towards a socio-ecological perspective will require long-lasting processes that build on social capacities, such as flexible institutions and multilevel governance systems.
    Keywords adaptive management ; carbon sequestration ; climate change ; decision making ; fish ; governance ; infrastructure ; sea level ; stakeholders ; water power ; Quebec
    Language English
    Dates of publication 2021-10
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 2681542-4
    ISSN 2212-0416
    ISSN 2212-0416
    DOI 10.1016/j.ecoser.2021.101349
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  9. Article ; Online: Sediment density flow distribution on wave‐influenced deltas

    Normandeau, A. / Eamer, Jordan B. R. / Bernatchez, Pascal / Didier, David / Lajeunesse, Patrick / Limoges, A. / Montero‐Serrano, Jean‐Carlos

    Sedimentology. 2023 Jan., v. 70, no. 1, p. 100-120

    2023  , Page(s) 100–120

    Abstract: Deltas are at the transition between fluvial and marine sedimentary environments where sediment density flows are often triggered during high river discharge events, forming submarine channels and sediment waves. On wave‐influenced deltas, longshore ... ...

    Abstract Deltas are at the transition between fluvial and marine sedimentary environments where sediment density flows are often triggered during high river discharge events, forming submarine channels and sediment waves. On wave‐influenced deltas, longshore currents are particularly efficient at transporting sediment alongshore, reducing the likelihood of sediment density flows from occurring at river mouths. This study describes four deltaic sedimentary systems at different stages of their evolution on a formerly glaciated continental inner shelf of eastern Canada in order to better understand the distribution of sediment density flows on wave‐influenced deltas. Three types of settings are recognized as being prone to sediment density flows: (i) in the early stages of wave‐influence and on large deltas, converging longshore currents can lead to offshelf sediment transport; (ii) on wave‐influenced to wave‐dominated deltas, a sandy spit can re‐route the river mouth and sediment density flows form where the spit intersects the delta lip; (iii) in advanced stages of wave‐dominated deltas and during their demise, rocky headlands are exposed and can intersect the slope, where off‐shelf sediment transport occurs. These types of sediment density flows were all characterized by debris flows or surge‐type turbidity currents which have limited offshore run‐out. More rarely, hyperpycnal flows form at the river mouths, especially where the river incises glaciomarine clays prone to landsliding in the river, which increases fine‐grained fluvial suspended sediment concentration. Overall, these results highlight the predominance of fluvial‐dominated deltas during a phase of relative sea‐level fall combined with high sediment supply. However, as soon as sediment supply diminishes, wave action remobilizes sediment alongshore modifying the distribution and types of sediment density flows occurring on wave‐influenced deltas.
    Keywords evolution ; river flow ; rivers ; sea level ; sediment transport ; sediments ; suspended sediment ; turbidity ; Canada
    Language English
    Dates of publication 2023-01
    Size p. 100-120.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 206889-8
    ISSN 0037-0746
    ISSN 0037-0746
    DOI 10.1111/sed.13033
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: Remote Sensing of Coastal Vegetation Phenology in a Cold Temperate Intertidal System: Implications for Classification of Coastal Habitats

    Légaré, Brigitte / Bélanger, Simon / Singh, Rakesh Kumar / Bernatchez, Pascal / Cusson, Mathieu

    Remote Sensing. 2022 June 23, v. 14, no. 13

    2022  

    Abstract: Intertidal vegetation provides important ecological functions, such as food and shelter for wildlife and ecological services with increased coastline protection from erosion. In cold temperate and subarctic environments, the short growing season has a ... ...

    Abstract Intertidal vegetation provides important ecological functions, such as food and shelter for wildlife and ecological services with increased coastline protection from erosion. In cold temperate and subarctic environments, the short growing season has a significant impact on the phenological response of the different vegetation types, which must be considered for their mapping using satellite remote sensing technologies. This study focuses on the effect of the phenology of vegetation in the intertidal ecosystems on remote sensing outputs. The studied sites were dominated by eelgrass (Zostera marina L.), saltmarsh cordgrass (Spartina alterniflora), creeping saltbush (Atriplex prostrata), macroalgae (Ascophyllum nodosum, and Fucus vesiculosus) attached to scattered boulders. In situ data were collected on ten occasions from May through October 2019 and included biophysical properties (e.g., leaf area index) and hyperspectral reflectance spectra (Rrs(λ)). The results indicate that even when substantial vegetation growth is observed, the variation in Rrs(λ) is not significant at the beginning of the growing season, limiting the spectral separability using multispectral imagery. The spectral separability between vegetation types was maximum at the beginning of the season (early June) when the vegetation had not reached its maximum growth. Seasonal time series of the normalized difference vegetation index (NDVI) values were derived from multispectral sensors (Sentinel-2 multispectral instrument (MSI) and PlanetScope) and were validated using in situ-derived NDVI. The results indicate that the phenology of intertidal vegetation can be monitored by satellite if the number of observations obtained at a low tide is sufficient, which helps to discriminate plant species and, therefore, the mapping of vegetation. The optimal period for vegetation mapping was September for the study area.
    Keywords Ascophyllum nodosum ; Atriplex prostrata ; Fucus vesiculosus ; Spartina alterniflora ; Zostera marina ; coasts ; cold ; leaf area index ; littoral zone ; macroalgae ; multispectral imagery ; normalized difference vegetation index ; phenology ; reflectance ; salt marshes ; satellites ; time series analysis ; wildlife
    Language English
    Dates of publication 2022-0623
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2513863-7
    ISSN 2072-4292
    ISSN 2072-4292
    DOI 10.3390/rs14133000
    Database NAL-Catalogue (AGRICOLA)

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