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  1. Article: In vitro

    Prišlin, Marina / Butorac, Ana / Bertoša, Rea / Kunić, Valentina / Ljolje, Ivana / Kostešić, Petar / Vlahović, Dunja / Naletilić, Šimun / Turk, Nenad / Brnić, Dragan

    Frontiers in veterinary science

    2024  Volume 11, Page(s) 1387174

    Abstract: Introduction: Canine adipose-derived mesenchymal stem cells (cAD-MSCs) hold therapeutic promise due to their regenerative potential, particularly within their secretome. However, concerns arise regarding the impact of : Methods: The study involved ... ...

    Abstract Introduction: Canine adipose-derived mesenchymal stem cells (cAD-MSCs) hold therapeutic promise due to their regenerative potential, particularly within their secretome. However, concerns arise regarding the impact of
    Methods: The study involved collecting abdominal adipose tissue samples from nine healthy female dogs, from which cAD-MSCs were extracted and cultured. Stem cells were validated through trilineage differentiation assays and flow cytometry immunophenotyping. Gene expression profiling using RT-qPCR array, and cAD-MSCs secretome LC-MS/MS analysis, were conducted at passages 3 and 6 to reveal gene expression and protein composition alterations during
    Results and discussion: The results demonstrate that the gene expression and secretome composition of cAD-MSCs were impacted by
    Language English
    Publishing date 2024-03-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2834243-4
    ISSN 2297-1769
    ISSN 2297-1769
    DOI 10.3389/fvets.2024.1387174
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Loss of thermotolerance in antibiotic-resistant

    Dekić Rozman, Svjetlana / Butorac, Ana / Bertoša, Rea / Hrenović, Jasna / Markeš, Marina

    International journal of environmental health research

    2021  Volume 32, Issue 7, Page(s) 1581–1593

    Abstract: ... ...

    Abstract Bacterium
    MeSH term(s) Acinetobacter baumannii ; Anti-Bacterial Agents/pharmacology ; Carbapenems ; Drug Resistance, Multiple, Bacterial ; Microbial Sensitivity Tests ; Proteomics ; Thermotolerance
    Chemical Substances Anti-Bacterial Agents ; Carbapenems
    Language English
    Publishing date 2021-03-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 1104887-6
    ISSN 1369-1619 ; 0960-3123
    ISSN (online) 1369-1619
    ISSN 0960-3123
    DOI 10.1080/09603123.2021.1898550
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3517: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Comparison of Traditional and Industrial Sausages Baranjski Kulen and Kulenova Seka Using Comprehensive Proteome, Peptidome and Metabolome Techniques.

    Šimunec, Valerija / Bertoša, Rea / Šporec, Anita / Lukić, Igor / Nejašmić, Diana / Lovrić, Marija / Dodig, Ivana / Vahčić, Nada / Butorac, Ana

    Food technology and biotechnology

    2022  Volume 60, Issue 2, Page(s) 178–191

    Abstract: Research background: Baranjski kulen is one of the most popular fermented meat sausages originating from Croatia. It has protected geographical indication, and is traditionally produced in the Baranja region of Croatia. Kulenova seka is a fermented ... ...

    Abstract Research background: Baranjski kulen is one of the most popular fermented meat sausages originating from Croatia. It has protected geographical indication, and is traditionally produced in the Baranja region of Croatia. Kulenova seka is a fermented sausage very similar to baranjski kulen, but it has a different calibre and consequently, a shorter time of production. In recent decades, due to the high demand and popularity of these products, industrially produced baranjski kulen and kulenova seka have become available on the market. This work aims to identify specific characteristics of traditional and industrial sausages baranjski kulen and kulenova seka on proteome, peptidome and metabolome level, which could potentially lead to better optimization of the industrial production process in order to obtain an equivalent to the traditional product.
    Experimental approach: Protein profiles of baranjski kulen and kulenova seka (traditional and industrial) were analysed using two-dimensional gel electrophoresis followed by differential display analysis and protein identification by mass spectrometry. Peptidomic profile was analysed
    Results and conclusions: The major identified characteristics of each product were: industrial baranjski kulen: specific degradation of myosin-1 and titin, overabundance of stress-related proteins and increased phenylalanine degradation; traditional baranjski kulen: decreased concentration of phenylalanine and overabundance of fructose-bisphosphate aldolase A and carbonic anhydrase 3; industrial kulenova seka - specific myosin-4 and haemoglobin subunit alpha degradation process; traditional kulenova seka - overabundance of dihydropyrimidine dehydrogenase [NADP(+)] and myosin light chain 1/3, skeletal muscle isoform, degradation of albumin and myoglobin, decreased concentrations of almost all free amino acids and increased amounts of smoke-derived volatile compounds. Presented results showed that potential product type-specific quality markers for each sausage could be found.
    Novelty and scientific contribution: In this preliminary communication, the first insights into protein degradation processes and generation of peptides, free amino acids and aroma compounds of industrial and traditional baranjski kulen and kulenova seka are presented. Although further research is needed to draw general conclusions, the specific profile of proteins, peptides, amino acids and volatile compounds represents the first step in the industrial production of sausages that meet the characteristics of traditional flavour.
    Language English
    Publishing date 2022-04-14
    Publishing country Croatia
    Document type Journal Article
    ZDB-ID 1340467-2
    ISSN 1330-9862
    ISSN 1330-9862
    DOI 10.17113/ftb.60.02.22.7374
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 7645: Show issues

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