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Article ; Online: Causes of Higher In-hospital Mortality Due to ACS in the Canary Islands and Possible Solutions.

Cordero, Alberto / Bertomeu Martínez, Vicente

Revista espanola de cardiologia (English ed.)

2019 Volume 72, Issue 6, Page(s) 443–444

MeSH term(s)	Acute Coronary Syndrome/mortality ; Acute Coronary Syndrome/prevention & control ; Hospital Mortality/trends ; Humans ; Primary Prevention/methods ; Risk Factors ; Spain/epidemiology
Language	Spanish
Publishing date	2019-03-09
Publishing country	Spain
Document type	Editorial
ISSN	1885-5857
ISSN (online)	1885-5857
DOI	10.1016/j.rec.2018.11.019
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Article ; Online: ¿Están justificados los objetivos terapéuticos de LDL?: controversias entre las guías europeas y americanas.

Bertomeu-Martínez, Vicente

Medwave

2016 Volume 16, Issue Suppl4, Page(s) e6825

Abstract: Dyslipidemia is one of the most important risk factors of the cardiovascular disease, so its treatment is one of the key strategies of cardiovascular prevention. Statins have been consolidated as the reference treatment for the reduction of serum ... ...

Title translation	Are therapeutic LDL goals justified? Controversies between the European and American guidelines.
Abstract	Dyslipidemia is one of the most important risk factors of the cardiovascular disease, so its treatment is one of the key strategies of cardiovascular prevention. Statins have been consolidated as the reference treatment for the reduction of serum cholesterol levels. There are some divergences in the treatment of dyslipidemia between American and European guidelines. This narrative review discusses the key points of this controversy.
MeSH term(s)	Cardiovascular Diseases/etiology ; Cardiovascular Diseases/prevention & control ; Cholesterol, LDL/blood ; Dyslipidemias/complications ; Dyslipidemias/drug therapy ; Europe ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage ; Practice Guidelines as Topic ; Risk Factors ; United States
Chemical Substances	Cholesterol, LDL ; Hydroxymethylglutaryl-CoA Reductase Inhibitors
Language	Spanish
Publishing date	2016-12-30
Publishing country	Chile
Document type	Journal Article ; Review
ZDB-ID	2818022-7
ISSN	0717-6384 ; 0717-6384
ISSN (online)	0717-6384
ISSN	0717-6384
DOI	10.5867/medwave.2016.6825
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Article ; Online: Reply to: "Determination of the optimal cut-off value of serum uric acid concentration in patients with acute coronary syndrome".

Cordero, Alberto / López-Pineda, Adriana / Bertomeu-Martínez, Vicente

Atherosclerosis

2018 Volume 272, Page(s) 241–242

MeSH term(s)	Acute Coronary Syndrome ; Humans ; Hyperuricemia ; Prognosis ; Risk Factors ; Uric Acid
Chemical Substances	Uric Acid (268B43MJ25)
Language	English
Publishing date	2018-03-10
Publishing country	Ireland
Document type	Letter ; Comment
ZDB-ID	80061-2
ISSN	1879-1484 ; 0021-9150
ISSN (online)	1879-1484
ISSN	0021-9150
DOI	10.1016/j.atherosclerosis.2018.03.011
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Zs.A 226: Show issues

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Jg. 1995 - 2021: Lesesall (1.OG)
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Article ; Online: A simple score to select patients for manual thrombectomy in emergent percutaneous coronary interventions: the DDTA score.

Cordero, Alberto / Freites, Alfonso / Escribano, David / Bertomeu-Martínez, Vicente / Zuazola, Pilar / Badimon, Lina

Journal of cardiovascular medicine (Hagerstown, Md.)

2020 Volume 21, Issue 8, Page(s) 595–602

Abstract: Background: The objective of manual thrombectomy is the removal of occlusive thrombus to improve the results of primary angioplasty. The better understanding of the factors associated with successful manual thrombectomy may provide relevant information ... ...

Abstract	Background: The objective of manual thrombectomy is the removal of occlusive thrombus to improve the results of primary angioplasty. The better understanding of the factors associated with successful manual thrombectomy may provide relevant information regarding thrombus formation and resolution. Methods: Observational study of all consecutive patients remitted for emergent percutaneous coronary intervention (PCI) in a single centre. Successful manual thrombectomy was considered when TIMI 3 was achieved after using the device and a score to predict successful manual thrombectomy was designed. Results: We included 618 patients, 65.1% treated with manual thrombectomy. No relevant differences in clinical features or time delays were observed between patients treated with vs. without manual thrombectomy, but manual thrombectomy treated patients received more often dual antiplatelet treatment (DAPT) before PCI. Final TIMI flow 3 was achieved in most patients and more frequently in manual thrombectomy treated patients (94.8 vs. 86.6%; P < 0.01). The successful manual thrombectomy rate was 81.3% and it was higher in patients pretreated with DAPT (89.0 vs. 73.3%; P < 0.01). The time delay to first medical contact was not related to the final TIMI 3, but it was significantly and negatively related to successful manual thrombectomy. According to the multivariate analysis, we designed the DDTA score: DAPT pretreatment (2), delay less than 2 h (3) or 2-4 h (2), TIMI flow improvement after wiring the lesion (2) and age less than 55 years (3). Patients with DDTA score at least 4 had lower no-reflow, mortality and major cardiovascular complications incidence. Conclusion: The DDTA score (DAPT pretreatment, time delays, TIMI flow improvement after wiring the lesion and age) identifies patients who benefit mostly from manual thrombectomy.
MeSH term(s)	Age Factors ; Aged ; Clinical Decision Rules ; Clinical Decision-Making ; Coronary Circulation ; Coronary Thrombosis/diagnostic imaging ; Coronary Thrombosis/physiopathology ; Coronary Thrombosis/therapy ; Cross-Sectional Studies ; Dual Anti-Platelet Therapy ; Emergencies ; Female ; Humans ; Male ; Middle Aged ; Percutaneous Coronary Intervention/adverse effects ; Predictive Value of Tests ; Recovery of Function ; Retrospective Studies ; Risk Assessment ; Risk Factors ; ST Elevation Myocardial Infarction/diagnostic imaging ; ST Elevation Myocardial Infarction/physiopathology ; ST Elevation Myocardial Infarction/therapy ; Thrombectomy ; Time Factors ; Time-to-Treatment ; Treatment Outcome
Language	English
Publishing date	2020-05-31
Publishing country	United States
Document type	Journal Article ; Observational Study
ZDB-ID	2223461-5
ISSN	1558-2035 ; 1558-2027
ISSN (online)	1558-2035
ISSN	1558-2027
DOI	10.2459/JCM.0000000000000992
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Zs.A 5210: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 559: Show issues

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Article ; Online: Cancer and Acute Coronary Syndrome. A Close, but Complicated Relationship. Response.

Cordero, Alberto / Bertomeu-González, Vicente / Núñez, Julio / Bertomeu-Martínez, Vicente

Revista espanola de cardiologia (English ed.)

2018 Volume 71, Issue 10, Page(s) 880–881

MeSH term(s)	Acute Coronary Syndrome ; Humans ; Neoplasms ; Registries ; Risk Factors
Language	Spanish
Publishing date	2018-08-07
Publishing country	Spain
Document type	Letter ; Comment
ISSN	1885-5857
ISSN (online)	1885-5857
DOI	10.1016/j.rec.2018.05.033
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Article ; Online: Role of cardiovascular magnetic resonance in the prognosis of patients with myocardial infarction with non-obstructive coronary arteries.

Vicente-Ibarra, Nuria / Feliu, Eloisa / Bertomeu-Martínez, Vicente / Cano-Vivar, Pedro / Carrillo-Sáez, Pilar / Morillas, Pedro / Ruiz-Nodar, Juan Miguel

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance

2021 Volume 23, Issue 1, Page(s) 83

Abstract: Background: It is estimated that 5% to 10% of patients with myocardial infarction (MI) present with no obstructive coronary artery lesions. Until now, most studies have focused on acute coronary syndrome, including different clinical entities with a ... ...

Abstract	Background: It is estimated that 5% to 10% of patients with myocardial infarction (MI) present with no obstructive coronary artery lesions. Until now, most studies have focused on acute coronary syndrome, including different clinical entities with a similar presentation encompassed under the term MINOCA (MI with non-obstructive coronary arteries). The aim of this study is to assess the prognosis of patients diagnosed with true infarction, confirmed by cardiovascular magnetic resonance (CMR), in the absence of significant coronary lesions. Methods: Prospective multicenter registry study, including 120 consecutive patients with a CMR-confirmed MI without obstructive coronary artery lesions. The primary clinical outcome was major adverse cardiovascular events (MACE: death, non-fatal infarction, stroke, or cardiac readmission), assessed over three years. Results: Seventy-six patients (63.3%) were admitted with a diagnosis of acute coronary syndrome, and 44 (36.6%) for other causes (mainly heart failure); the definitive diagnosis was established by CMR. Most patients (64.2%) were men, and the mean age was 58.8 ± 13.5 years. Patients presented with small infarcts: 83 (69.1%) showed late gadolinium enhancement (LGE) in one or two myocardial segments, mainly transmural (in 77.5% of patients) and with a preserved left ventricular ejection fraction (median 54.8%, interquartile range 37-62). The most frequent infarct location was inferolateral (n = 38, 31.7%). During follow-up, 43 patients (35.8%) experienced a MACE, including 9 (7.5%) who died. In multivariable analysis, LGE in two versus one myocardial segment doubled the risk of adverse cardiac events (hazard ratio [HR] 2.32, 95% confidence interval [CI] 0.97-5.83, p = 0.058). Involvement of three or more myocardial segments almost tripled the risk (HR 2.71, 95% CI 1.04-7.04, p = 0.040 respectively). Conclusions: Patients with true MI but without significant coronary artery lesions predominantly had small infarcts. Myocardial 3-segment LGE involvement is associated with a significantly higher risk of adverse cardiac events.
MeSH term(s)	Aged ; Contrast Media ; Coronary Vessels ; Gadolinium ; Humans ; Magnetic Resonance Imaging, Cine ; Magnetic Resonance Spectroscopy ; Male ; Middle Aged ; Myocardial Infarction/diagnostic imaging ; Predictive Value of Tests ; Prognosis ; Prospective Studies ; Risk Assessment ; Stroke Volume ; Ventricular Function, Left
Chemical Substances	Contrast Media ; Gadolinium (AU0V1LM3JT)
Language	English
Publishing date	2021-07-01
Publishing country	England
Document type	Journal Article ; Multicenter Study
ZDB-ID	1458034-2
ISSN	1532-429X ; 1097-6647
ISSN (online)	1532-429X
ISSN	1097-6647
DOI	10.1186/s12968-021-00773-w
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Zs.A 5045: Show issues

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Article: Impact of Integrated Care Management on Clinical Outcomes in Atrial Fibrillation Patients: A Report From the FANTASIIA Registry.

Esteve-Pastor, María Asunción / Ruiz-Ortiz, Martín / Muñiz, Javier / Roldán-Rabadán, Inmaculada / Otero, Déborah / Cequier, Ángel / Bertomeu-Martínez, Vicente / Badimón, Lina / Anguita, Manuel / Lip, Gregory Y H / Marín, Francisco

Frontiers in cardiovascular medicine

2022 Volume 9, Page(s) 856222

Abstract: Background: An integrated and holistic approach is increasingly advocated in patients with atrial fibrillation (AF), based on the "Atrial fibrillation Better Care (ABC) pathway: A, Avoid stroke with anticoagulation; B, better symptom management; C, ... ...

Abstract	Background: An integrated and holistic approach is increasingly advocated in patients with atrial fibrillation (AF), based on the "Atrial fibrillation Better Care (ABC) pathway: A, Avoid stroke with anticoagulation; B, better symptom management; C, cardiovascular and comorbidity risk management." The aim of this study was to examine the prevalence of adherence to each component of the ABC pathway and to analyze its impact on long-term prognosis in the "real-world" cohort of AF patients from the FANTASIIA registry. Methods: This prospective study included consecutive AF outpatients anticoagulated with direct oral anticoagulants (DOAC) or vitamin K antagonists (VKA) from June 2013 to October 2014. From the ABC pathway, adherence to the "A criterion" was defined by a time in the therapeutic range (TTR) ≥ 70% or correct dose with DOAC; "B criterion" adherence was defined by a European Heart Rhythm Association (EHRA) Symptom Scale I-II; and "C criterion" adherence was defined as optimized risk factors and comorbidity management. Baseline features and embolic events, severe bleeding, and all-cause and cardiovascular mortality rates up to 3 years of follow-up were analyzed, and a Cox multivariate analysis was performed to investigate the role of each component of the ABC pathway in predicting major events. Results: A total of 1,955 AF patients (age: 74.4 ± 9.4 years; 43.2% female patients) were included in this study: adherence to A criterion was observed in 920 (47.1%) patients; adherence to B criterion was observed in 1,791 (91.6%) patients; and adherence to C criterion was observed in 682 (34.8%) patients. Only 394 (20.2%) of the whole population had good control of AF according to the ABC pathway. After a median follow-up of 1,078 days (IQR: 766-1,113), adherence to A criterion was independently associated with reduced cardiovascular mortality [HR: 0.67, 95%CI (0.45-0.99); Conclusion: In real-world anticoagulated AF patients from FANTASIIA registry, we observed a lack of adherence to integrated care management of AF following the ABC pathway. AF managed according to the ABC pathway was associated with a significant reduction in adverse outcomes during long follow-up, suggesting the benefit of a holistic and integrated approach to AF management.
Language	English
Publishing date	2022-05-02
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2781496-8
ISSN	2297-055X
ISSN	2297-055X
DOI	10.3389/fcvm.2022.856222
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Article ; Online: Clinical effectiveness of a cardiology outpatient management plan to reduce inefficiency in consultations.

González-Llopis, Francisco / Palazón-Bru, Antonio / Mares-García, Emma / Carbonell-Torregrosa, María De Los Ángeles / Bertomeu-Martínez, Vicente / Gil-Guillén, Vicente Francisco

Postgraduate medicine

2020 Volume 133, Issue 2, Page(s) 166–172

Abstract: ... ...

Abstract	Objectives
MeSH term(s)	Ambulatory Care/methods ; Ambulatory Care/organization & administration ; Ambulatory Care/standards ; Cardiology/methods ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/therapy ; Female ; Heart Function Tests/methods ; Heart Function Tests/statistics & numerical data ; Humans ; Male ; Middle Aged ; Outcome Assessment, Health Care ; Quality Improvement/organization & administration ; Referral and Consultation/standards ; Referral and Consultation/statistics & numerical data ; Spain/epidemiology ; Treatment Outcome
Language	English
Publishing date	2020-11-03
Publishing country	England
Document type	Journal Article
ZDB-ID	410138-8
ISSN	1941-9260 ; 0032-5481
ISSN (online)	1941-9260
ISSN	0032-5481
DOI	10.1080/00325481.2020.1839298
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Article ; Online: Heart Failure, Nonvalvular Atrial Fibrillation and Anticoagulation Control With Vitamin K Antagonists.

Anguita Sánchez, Manuel / Bertomeu Martínez, Vicente / Cequier Fillat, Ángel

Revista espanola de cardiologia (English ed.)

2016 Volume 69, Issue 1, Page(s) 75–76

MeSH term(s)	Anticoagulants/therapeutic use ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Heart Failure/complications ; Heart Failure/drug therapy ; Humans ; Thromboembolism/etiology ; Thromboembolism/prevention & control ; Vitamin K/antagonists & inhibitors
Chemical Substances	Anticoagulants ; Vitamin K (12001-79-5)
Language	English
Publishing date	2016-01
Publishing country	Spain
Document type	Letter ; Research Support, Non-U.S. Gov't
ISSN	1885-5857
ISSN (online)	1885-5857
DOI	10.1016/j.rec.2015.08.017
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Article ; Online: Degree of Anticoagulation Control in Patients With Atrial Fibrillation in Spain: Need to Minimize Biases and Contextualize Results. Response by Anguita Sánchez et al.

Anguita Sánchez, Manuel / Bertomeu Martínez, Vicente / Cequier Fillat, Angel

Revista espanola de cardiologia (English ed.)

2016 Volume 69, Issue 3, Page(s) 356

MeSH term(s)	Anticoagulants/therapeutic use ; Atrial Fibrillation/drug therapy ; Blood Coagulation ; Humans ; Spain ; Warfarin/therapeutic use
Chemical Substances	Anticoagulants ; Warfarin (5Q7ZVV76EI)
Language	English
Publishing date	2016-03
Publishing country	Spain
Document type	Comment ; Letter ; Research Support, Non-U.S. Gov't
ISSN	1885-5857
ISSN (online)	1885-5857
DOI	10.1016/j.rec.2015.11.016
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