Article ; Online: Exercise as an Immune Boost: Mechanism-Driven Support for Lifestyle Interventions.
2023 Volume 11, Issue 9, Page(s) 1158
Abstract: Modifiable host factors have demonstrated promise to enhance responses to immunotherapy. In this issue, Savage et al. investigated the use of aerobic exercise to enhance antitumor immunity in a murine model of melanoma. They show that treadmill running ... ...
Abstract | Modifiable host factors have demonstrated promise to enhance responses to immunotherapy. In this issue, Savage et al. investigated the use of aerobic exercise to enhance antitumor immunity in a murine model of melanoma. They show that treadmill running improves tumor vasculature and alters both T-cell and myeloid-cell infiltration of the tumor via an ERK5-dependent mechanism, adding to the growing evidence supporting the immune-mediated antitumor effects of exercise. See related article by Savage et al., p. 1168 (3). |
---|---|
MeSH term(s) | Humans ; Mice ; Animals ; Phosphorylation ; CD8-Positive T-Lymphocytes/immunology ; Melanoma/immunology ; Immunotherapy ; Life Style ; Tumor Microenvironment |
Language | English |
Publishing date | 2023-08-08 |
Publishing country | United States |
Document type | Journal Article ; Comment |
ZDB-ID | 2732489-8 |
ISSN | 2326-6074 ; 2326-6066 |
ISSN (online) | 2326-6074 |
ISSN | 2326-6066 |
DOI | 10.1158/2326-6066.CIR-23-0585 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
Zs.A 7022: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.