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  1. Article ; Conference proceedings: Hereditäre Kopf-Hals-Paragangliome am Beispiel einer Familie mit SDHD-Mutation – Falldarstellungen und Review

    Bewarder, J / Böttcher, A / Betz, CS

    Laryngo-Rhino-Otologie

    2019  Volume 98, Issue S 02

    Event/congress Abstract- und Posterband - 90. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn - Digitalisierung in der HNO-Heilkunde, Estrel Congress Center Berlin, 2019-05-29
    Language German
    Publishing date 2019-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0935-8943 ; 0340-1588
    ISSN (online) 1438-8685
    ISSN 0935-8943 ; 0340-1588
    DOI 10.1055/s-0039-1686123
    Database Thieme publisher's database

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  2. Article ; Conference proceedings: Hereditary head and neck paragangliomas using the example of a family with SDHD mutation – case presentations and review

    Bewarder, J / Böttcher, A / Betz, CS

    Laryngo-Rhino-Otologie

    2019  Volume 98, Issue S 02

    Event/congress Abstract- und Posterband - 90. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn - Digitalisierung in der HNO-Heilkunde, Estrel Congress Center Berlin, 2019-05-29
    Language English
    Publishing date 2019-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0935-8943 ; 0340-1588
    ISSN (online) 1438-8685
    ISSN 0935-8943 ; 0340-1588
    DOI 10.1055/s-0039-1686346
    Database Thieme publisher's database

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  3. Article: A Four-Generational Report on Hereditary Head and Neck Paraganglioma.

    Trache, Mihnea Cristian / Bewarder, Julian / Betz, Christian Stephan / Möckelmann, Nikolaus / Böttcher, Arne

    Cureus

    2022  Volume 14, Issue 4, Page(s) e24143

    Abstract: Background This article investigates the inheritance, penetrance, clinical presentation, and therapeutic outcomes of hereditary head and neck paragangliomas (HNPGLs) by offering a four-generational report of an 18-member family affected by this rare ... ...

    Abstract Background This article investigates the inheritance, penetrance, clinical presentation, and therapeutic outcomes of hereditary head and neck paragangliomas (HNPGLs) by offering a four-generational report of an 18-member family affected by this rare condition. Methodology Information was compiled by examination of patients and a review of medical records and correspondence (retrospective case series). Results Six members of the 18-member family were diagnosed with HNPGL between 2002 and 2018. A known pathogenic point mutation in subunit D of the succinyl dehydrogenase complex (SDHD, c.317G>T, p.Gly106Val) was responsible for the tumor phenotype. The mutation could be revealed in seven family members, three diseased adults, one healthy adult, and three healthy children, out of the nine who consented to gene testing. The median age at diagnosis was 33.5 years (range: 22-50 years). Five of the eight primary tumors were glomus caroticum, two were glomus jugulare, and one was a glomus vagale tumor. The therapeutic approaches were multimodal and included embolization therapy, surgery, radiation, and watchful waiting. Follow-up was reported for five of the six patients (mean follow-up of 34.8 months after primary therapy); three showed no disease progression or recurrence. Conclusions This study exemplifies the autosomal dominant, parent-of-origin-dependent inheritance and the high disease penetrance in hereditary paraganglioma-pheochromocytoma syndromes. Six out of a total of eight adult descendants (75%) of the original SDHD mutation carrier developed tumors, and the morbidity associated with the disease as well as its therapy was especially high in late-diagnosed, advanced cases. This substantiates the necessity for early radiologic surveillance and genetic testing.
    Language English
    Publishing date 2022-04-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.24143
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Conference proceedings: Extensive cholesteatoma of the temporal bone with compression of the posterior fossa and midline displacement

    Bewarder, J / Tóth, M / Münscher, A

    Laryngo-Rhino-Otologie

    2018  Volume 97, Issue S 02

    Event/congress Abstract- und Posterband - 89. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn - Forschung heute - Zukunft morgen, Musik- und Kongresshalle (MuK) Lübeck, 2018-05-09
    Language English
    Publishing date 2018-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0935-8943 ; 0340-1588
    ISSN (online) 1438-8685
    ISSN 0935-8943 ; 0340-1588
    DOI 10.1055/s-0038-1640260
    Database Thieme publisher's database

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  5. Article ; Conference proceedings: Felsenbeincholesteatom mit Kompression der hinteren Schädelgrube und Verlagerung der Mittellinie

    Bewarder, J / Tóth, M / Münscher, A

    Laryngo-Rhino-Otologie

    2018  Volume 97, Issue S 02

    Event/congress Abstract- und Posterband - 89. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn - Forschung heute - Zukunft morgen, Musik- und Kongresshalle (MuK) Lübeck, 2018-05-09
    Language German
    Publishing date 2018-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0935-8943 ; 0340-1588
    ISSN (online) 1438-8685
    ISSN 0935-8943 ; 0340-1588
    DOI 10.1055/s-0038-1640259
    Database Thieme publisher's database

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  6. Article ; Conference proceedings: Bezold’s abscess and Lemierre’s syndrome after acute exacerbation of a chronic otitis media – A rare but severe complication.

    Breda, Philippe Christophe / Bewarder, Julian / Betz, Christian Stephan / Böttcher, Arne

    Laryngo-Rhino-Otologie

    (Abstract- und Posterband)

    2022  Volume 101, Issue S 02

    Event/congress Abstract- und Posterband - 93. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn Interface - Fokus Mensch im Zeitalter der technisierten Medizin, Deutsche Messe Hannover, 2022-05-25
    Series title Abstract- und Posterband
    Language English
    Publishing date 2022-05-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0935-8943 ; 0340-1588
    ISSN (online) 1438-8685
    ISSN 0935-8943 ; 0340-1588
    DOI 10.1055/s-0042-1746552
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  7. Article ; Conference proceedings: Postoperative Vitalitätskontrolle von Lappentransplantaten mittels Hyperspektraler Bildgebung

    Wittig, Lukas / Betz, Christian Stephan / Bewarder, Julian / Böttcher, Arne / Stölzel, Katharina / Eggert, Dennis

    Laryngo-Rhino-Otologie

    (Abstract- und Posterband)

    2022  Volume 101, Issue S 02

    Event/congress Abstract- und Posterband - 93. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn Interface - Fokus Mensch im Zeitalter der technisierten Medizin, Deutsche Messe Hannover, 2022-05-25
    Series title Abstract- und Posterband
    Language German
    Publishing date 2022-05-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0935-8943 ; 0340-1588
    ISSN (online) 1438-8685
    ISSN 0935-8943 ; 0340-1588
    DOI 10.1055/s-0042-1747260
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  8. Article ; Conference proceedings: Postoperative flap monitoring using Hyperspectral Imaging – A case series

    Wittig, Lukas / Betz, Christian Stephan / Bewarder, Julian / Böttcher, Arne / Stölzel, Katharina / Eggert, Dennis

    Laryngo-Rhino-Otologie

    (Abstract- und Posterband)

    2022  Volume 101, Issue S 02

    Event/congress Abstract- und Posterband - 93. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn Interface - Fokus Mensch im Zeitalter der technisierten Medizin, Deutsche Messe Hannover, 2022-05-25
    Series title Abstract- und Posterband
    Language English
    Publishing date 2022-05-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0935-8943 ; 0340-1588
    ISSN (online) 1438-8685
    ISSN 0935-8943 ; 0340-1588
    DOI 10.1055/s-0042-1746632
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  9. Article ; Conference proceedings: Hyperspektrale Bildgebung zur postoperativen Vitalitätskontrolle freier und gestielter Lappentransplantate

    Schmitz, Thorsten / Wittig, Lukas / Bewarder, Julian / Stölzel, Katharina / Böttcher, Arne / Betz, ChristianS. / Eggert, Dennis

    Laryngo-Rhino-Otologie

    2023  Volume 102, Issue S 02

    Event/congress 94. Jahresversammlung Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn, Congress Center Leipzig, 2023-05-17
    Language German
    Publishing date 2023-05-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0935-8943 ; 0340-1588
    ISSN (online) 1438-8685
    ISSN 0935-8943 ; 0340-1588
    DOI 10.1055/s-0043-1766519
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  10. Article ; Conference proceedings: Hyperspectral imaging in free and pedicled flap monitoring

    Schmitz, Thorsten / Wittig, Lukas / Bewarder, Julian / Stölzel, Katharina / Böttcher, Arne / Betz, S. Christian / Eggert, Dennis

    Laryngo-Rhino-Otologie

    2023  Volume 102, Issue S 02

    Event/congress 94th Annual Meeting German Society of Oto-Rhino-Laryngology, Head and Neck Surgery e.V., Bonn, Congress Center Leipzig, 2023-05-17
    Language English
    Publishing date 2023-05-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0935-8943 ; 0340-1588
    ISSN (online) 1438-8685
    ISSN 0935-8943 ; 0340-1588
    DOI 10.1055/s-0043-1767112
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