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  1. Article ; Online: Impact of the COVID-19 Pandemic and Lockdown on Gastric Bypass Results at 1-Year Follow-up.

    Barranquero, Alberto G / Cimpean, Sorin / Raglione, Dario / Cadière, Benjamin / Maréchal, Marie-Thérèse / Pau, Luca / Bez, Mattia / Cadière, Guy-Bernard

    Obesity surgery

    2021  Volume 31, Issue 10, Page(s) 4511–4518

    Abstract: Purpose: The COVID-19 pandemic caused a lockdown in many countries, which induced negative dietary habits and sedentary behavior. Studies suggest that weight loss of patients undergoing bariatric surgery was equally affected. The aim was to evaluate the ...

    Abstract Purpose: The COVID-19 pandemic caused a lockdown in many countries, which induced negative dietary habits and sedentary behavior. Studies suggest that weight loss of patients undergoing bariatric surgery was equally affected. The aim was to evaluate the impact of COVID-19 on weight loss, obesity-related comorbidities, and nutritional status at 1-year follow-up after gastric bypass (GB).
    Methods: Retrospective observational case-control study of patients undergoing primary GB in a tertiary referral Belgian center. COVID-19 period group was composed by those whose 1-year postoperative period was affected by the COVID-19 pandemic and lockdown: from October 1, 2019, to March 31, 2020. The control group was composed of patients operated from October 1, 2018, to March 31, 2019. Electronic clinical records were reviewed searching: baseline characteristics, weight and comorbidities evolution, and biochemical values.
    Results: A total of 47 patients in the COVID-19 period group and 66 in the non-COVID-19 period group were analyzed. There were no significant differences in baseline characteristics. A reduced weight loss was observed at 1-year follow-up, in terms of percentage of excess weight loss (%EWL) (82.4% [SD: 21.6] vs. 82.4% [SD: 21.6]; p: 0.043) and body mass index (BMI) (27.8 kg/m
    Conclusion: The COVID-19 pandemic and lockdown had an impact on weight loss at 1-year follow-up after gastric bypass.
    MeSH term(s) Body Mass Index ; COVID-19 ; Case-Control Studies ; Communicable Disease Control ; Follow-Up Studies ; Gastric Bypass ; Humans ; Laparoscopy ; Obesity, Morbid/surgery ; Pandemics ; Retrospective Studies ; SARS-CoV-2 ; Treatment Outcome
    Language English
    Publishing date 2021-08-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-021-05640-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Extended time interval between diagnosis and surgery does not improve the outcome in patients operated for resection or ablation of breast cancer liver metastases.

    Lucidi, Valerio / Bohlok, Ali / Liberale, Gabriel / Bez, Mattia / Germanova, Desislava / Bouazza, Fikri / Demetter, Pieter / Larsimont, Denis / Aftimos, Philippe / Smoll, Nicolas Roydon / Donckier, Vincent

    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

    2019  Volume 46, Issue 2, Page(s) 229–234

    Abstract: Background: Breast cancer liver metastases (BCLM) is considered a systemic disease with poorly defined selection criteria for surgery and little evidence for the appropriate timing of surgery.: Methods: Postoperative outcomes of patients operated for ...

    Abstract Background: Breast cancer liver metastases (BCLM) is considered a systemic disease with poorly defined selection criteria for surgery and little evidence for the appropriate timing of surgery.
    Methods: Postoperative outcomes of patients operated for BCLM were retrospectively reviewed and compared based on the timing of surgery, with the early surgery (ES) group treated ≤12 months after BCLM diagnosis, and late surgery (LS) group operated >12 months after diagnosis.
    Results: Seventy-two patients with BCLM underwent liver surgery, including 37 and 35 in the ES and LS groups, respectively. Demographic and preoperative characteristics were similar between the groups, except that multifocal liver disease was more frequent in the LS group (p = 0.008). The LS group had a morbidity rate of 38%, compared to 11% in the ES group (p = 0.015). No postoperative deaths occurred. In the whole cohort, median progression-free (PFS) and overall survival (OS) were 19 and 50 months, respectively, and 1-, 3- and 5-year PFS and OS were 63%, 41%, 24% and 93%, 66%, 43%, respectively, with no significant difference observed between the ES and LS groups. Multivariate analysis revealed that breast cancer progesterone receptor negativity (HR = 3.34, p = 0.03) and a size of LM > 40 mm (HR = 3.11, p = 0.01) were significant negative prognostic factors for PFS. Only a size of LM > 40 mm (HR = 2.79, p = 0.008) was significantly associated with shorter OS.
    Conclusion: A prolonged preoperative observational period does not improve long-term outcomes after liver surgery in patients with resectable BCLM, suggesting that early management can safely be proposed to those patients, with good oncological outcomes.
    MeSH term(s) Adult ; Aged ; Breast Neoplasms/pathology ; Female ; Hepatectomy ; Humans ; Liver Neoplasms/diagnosis ; Liver Neoplasms/mortality ; Liver Neoplasms/secondary ; Liver Neoplasms/surgery ; Middle Aged ; Retrospective Studies ; Time Factors
    Language English
    Publishing date 2019-10-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 632519-1
    ISSN 1532-2157 ; 0748-7983
    ISSN (online) 1532-2157
    ISSN 0748-7983
    DOI 10.1016/j.ejso.2019.10.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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