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Article ; Online: HIV Preexposure Prophylaxis Among People With Substance Use Disorder-The Road Less Traveled.

Bhandari, Ruchi

JAMA network open

2022 Volume 5, Issue 7, Page(s) e2221352

MeSH term(s)	HIV Infections/drug therapy ; HIV Infections/prevention & control ; Humans ; Pre-Exposure Prophylaxis ; Substance-Related Disorders/prevention & control
Language	English
Publishing date	2022-07-01
Publishing country	United States
Document type	Journal Article ; Comment
ISSN	2574-3805
ISSN (online)	2574-3805
DOI	10.1001/jamanetworkopen.2022.21352
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Article: Online Yoga and Ayurveda Intervention as Tertiary Prevention of Psychological Comorbidities in COVID-19 Survivors: A Randomized Controlled Trial.

Bhandari, Rudra

Annals of neurosciences

2022 Volume 29, Issue 4, Page(s) 233–244

Abstract: Background and purpose: About 56% of symptomatic COVID-19 survivors have been found with neuropsychological comorbidities, such as depression, anxiety, posttraumatic stress disorders (PTSD), and impaired quality of life (QoL). Alongside, antimicrobial, ... ...

Abstract	Background and purpose: About 56% of symptomatic COVID-19 survivors have been found with neuropsychological comorbidities, such as depression, anxiety, posttraumatic stress disorders (PTSD), and impaired quality of life (QoL). Alongside, antimicrobial, anti-inflammatory, neuroprotective, regenerative, immunomodulatory, cardio-pulmonary health promotive, and psychological benefits of yogic and Ayurvedic intervention are well documented. Therefore, this study aimed to assess the effect of online Yoga (OYI) and Yoga cum Ayurveda intervention (OYAI) on COVID-19-induced depression, anxiety, PTSD, and poor QoL. Method: Seventy-two participants (males/females: 33/26) with at least a 3-month back history of symptomatic COVID-19 infection and age (mean ± SD: 32.33 ± 9.9 and 33.04 ± 12.9 for males and females, respectively) were recruited from Patanjali Ayurveda Hospital, Haridwar, India, and All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India, before random allocation into an equal-sized control group (CG), Yoga group (YG) and Yoga cum concoction (YCG) group. Split-plot analysis of variance and Kruskal-Wallis tests with Bonferroni adjusted Results: Both the treatments-the 30-day OYI and OYAI, significantly improved depression ( Conclusion: OYAI may better ameliorate COVID-19-induced psychological comorbidities than OYI with no adverse effects.
Language	English
Publishing date	2022-08-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2576191-2
ISSN	0976-3260 ; 0972-7531
ISSN (online)	0976-3260
ISSN	0972-7531
DOI	10.1177/09727531221117623
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Article: Green hydrogen production potential in West Africa – Case of Niger

Bhandari, Ramchandra

Renewable energy. 2022 Aug., v. 196

2022

Abstract: Niger offers the possibility of producing green hydrogen due to its high solar energy potential. Due to the still growing domestic oil and coal industry, the use of green hydrogen in the country currently seems unlikely at the higher costs of hydrogen as ...

Abstract	Niger offers the possibility of producing green hydrogen due to its high solar energy potential. Due to the still growing domestic oil and coal industry, the use of green hydrogen in the country currently seems unlikely at the higher costs of hydrogen as an energy vector. However, the export of green hydrogen to industrialized countries could be an option. In 2020, a hydrogen partnership has been established between Germany and Niger. The potential import of green hydrogen represents an option for Germany and other European countries to decarbonize domestic energy supply. Currently there are no known projects for the electrolytic production of hydrogen in Niger. In this work, potential hydrogen demand across electricity and transport sectors is forecasted until 2040. The electricity demand in 2040 is expected at 2934 GWh and the gasoline and diesel demand at 964 m³ and 2181 m³ respectively. Accordingly, the total hydrogen needed to supply electricity and the transport sector (e.g. to replace 1% gasoline and diesel demand in 2040) is calculated at 0.0117 Mt. Only a small fraction of 5% of the land area in Niger would be sufficient to generate the required electricity from solar PV to produce hydrogen.
Keywords	coal industry ; electricity ; energy ; exports ; gasoline ; hydrogen ; hydrogen production ; imports ; industrialization ; oils ; solar energy ; Germany ; Niger
Language	English
Dates of publication	2022-08
Size	p. 800-811.
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	2001449-1
ISSN	1879-0682 ; 0960-1481
ISSN (online)	1879-0682
ISSN	0960-1481
DOI	10.1016/j.renene.2022.07.052
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Risk of Frailty in Survivors of Childhood Cancer: The Role of Socioenvironmental Factors.

Bhandari, Rusha / Armenian, Saro H

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

2023 Volume 32, Issue 8, Page(s) 997–998

Abstract: The identification of frailty among relatively young survivors of childhood cancer has led to a growing body of work aimed at examining potential risk factors and interventions to decrease its burden in this population. In the accompanying article, ... ...

Abstract	The identification of frailty among relatively young survivors of childhood cancer has led to a growing body of work aimed at examining potential risk factors and interventions to decrease its burden in this population. In the accompanying article, Schwartz and colleagues present their findings regarding the association between neighborhood characteristics and frailty in survivors of childhood cancer and show that survivors living in resource poor neighborhoods had increased odds of frailty compared with those in resource-rich neighborhoods. This work further supports the need for focused educational initiatives and nutrition and exercise interventions to improve survivors' quality of health. See related article by Schwartz et al., p. 1021.
MeSH term(s)	Humans ; Child ; Cancer Survivors ; Cohort Studies ; Frailty/epidemiology ; Frailty/etiology ; Neoplasms/therapy ; Survivors ; Neighborhood Characteristics
Language	English
Publishing date	2023-07-29
Publishing country	United States
Document type	Research Support, N.I.H., Extramural ; Journal Article ; Comment
ZDB-ID	1153420-5
ISSN	1538-7755 ; 1055-9965
ISSN (online)	1538-7755
ISSN	1055-9965
DOI	10.1158/1055-9965.EPI-23-0642
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Jg. 1995 - 2021: Lesesall (2.OG)
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Article ; Online: Epiploic appendagitis: a commonly undiagnosed non-surgical acute abdominal emergency.

Ekladious, Adel / Bhandari, Ritesh

Internal medicine journal

2023 Volume 53, Issue 7, Page(s) 1265–1268

Abstract: Epiploic appendagitis is a rare cause of acute abdomen and is diagnostically challenging as it mimics common causes of acute abdomen. However, advancements in computerised tomography/Ultrasound imaging have improved the frequency and confidence of ... ...

Abstract	Epiploic appendagitis is a rare cause of acute abdomen and is diagnostically challenging as it mimics common causes of acute abdomen. However, advancements in computerised tomography/Ultrasound imaging have improved the frequency and confidence of diagnosing epiploic appendagitis, preventing unnecessary surgeries. We present a case of an acute abdomen who had to undergo laparoscopy before being diagnosed with epiploic appendagitis, underscoring the difficulty in diagnosis.
MeSH term(s)	Humans ; Abdomen, Acute/diagnostic imaging ; Abdomen, Acute/etiology ; Diagnosis, Differential ; Tomography, X-Ray Computed ; Ultrasonography ; Laparoscopy/adverse effects
Language	English
Publishing date	2023-07-20
Publishing country	Australia
Document type	Case Reports ; Journal Article
ZDB-ID	2045436-3
ISSN	1445-5994 ; 1444-0903
ISSN (online)	1445-5994
ISSN	1444-0903
DOI	10.1111/imj.16157
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Article ; Online: Over-the-counter Medication Use among Patients Presenting with Fever in the Emergency Department in a Tertiary Care Hospital.

Ghimire, Mrikchhya / Risal, Ujjwol Prasad / Bhandari, Rabin

JNMA; journal of the Nepal Medical Association

2024 Volume 62, Issue 269, Page(s) 30–33

Abstract: Introduction: Over-the-counter medication use is commonly practised all over the world. However, in a developing country like Nepal, antibiotics form an essential component of OTC drugs. Fever is one of the most common clinical complaints which makes a ... ...

Abstract	Introduction: Over-the-counter medication use is commonly practised all over the world. However, in a developing country like Nepal, antibiotics form an essential component of OTC drugs. Fever is one of the most common clinical complaints which makes a patient go to the local pharmacy for over-the-counter medication. This study aimed to find out the prevalence of over-the-counter medication use among patients presenting with fever in the Emergency Department in a tertiary care hospital. Methods: This descriptive cross-sectional study was conducted among patients who visited the Emergency Department with the complaint of at least one episode of documented or undocumented fever after obtaining ethical approval from the Institutional Review Committee. Data collection was conducted from 24 June 2022 to 30 September 2022. Convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval. Results: Among 332 patients, 314 (94.58%) (92.14-97.02, 95% Confidence Interval) patients used over-the-counter medication. Antibiotic use was seen in 221 (70.38%) patients. Conclusions: The prevalence of over-the-counter medication use among patients with fever was found to be higher than the studies conducted in similar studies. Keywords: emergency departments; fever; prevalence.
MeSH term(s)	Humans ; Cross-Sectional Studies ; Tertiary Care Centers ; Emergency Service, Hospital ; Anti-Bacterial Agents/therapeutic use ; Fever/drug therapy ; Fever/epidemiology
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2024-01-02
Publishing country	Nepal
Document type	Journal Article
ZDB-ID	2209910-4
ISSN	1815-672X ; 0028-2715
ISSN (online)	1815-672X
ISSN	0028-2715
DOI	10.31729/jnma.8401
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Article ; Online: Horizontal magnetic tweezers and its applications in single molecule micromanipulation experiments.

Gaire, Santosh / Bhandari, Rajendra / Pegg, Ian / Sarkar, Abhijit

Methods in enzymology

2024 Volume 694, Page(s) 191–207

Abstract: Magnetic tweezers (MTs) have become indispensable tools for gaining mechanistic insights into the behavior of DNA-processing enzymes and acquiring detailed, high-resolution data on the mechanical properties of DNA. Currently, MTs have two distinct ... ...

Abstract	Magnetic tweezers (MTs) have become indispensable tools for gaining mechanistic insights into the behavior of DNA-processing enzymes and acquiring detailed, high-resolution data on the mechanical properties of DNA. Currently, MTs have two distinct designs: vertical and horizontal (or transverse) configurations. While the vertical design and its applications have been extensively documented, there is a noticeable gap in comprehensive information pertaining to the design details, experimental procedures, and types of studies conducted with horizontal MTs. This article aims to address this gap by providing a concise overview of the fundamental principles underlying transverse MTs. It will explore the multifaceted applications of this technique as an exceptional instrument for scrutinizing DNA and its interactions with DNA-binding proteins at the single-molecule level.
MeSH term(s)	DNA/chemistry ; Magnetic Phenomena ; Micromanipulation/methods ; Nanotechnology/methods ; Optical Tweezers
Chemical Substances	DNA (9007-49-2)
Language	English
Publishing date	2024-02-05
Publishing country	United States
Document type	Journal Article ; Review
ISSN	1557-7988
ISSN (online)	1557-7988
DOI	10.1016/bs.mie.2023.12.015
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Prediction of Postoperative Major Complications in Pancreaticoduodenectomy -a Prospective Comparative Analysis of Braga and WHipple-ABACUS Scores.

Sah, D N / Lakhey, P J / Bhandari, R S

Kathmandu University medical journal (KUMJ)

2024 Volume 21, Issue 82, Page(s) 125–132

Abstract: Background Major complications following pancreaticoduodenectomy have a severely deleterious effect on postoperative course, rather than just occurrence of pancreatic fistula. Surgical risk stratification with Braga and WHipple-ABACUS have been proposed ... ...

Abstract	Background Major complications following pancreaticoduodenectomy have a severely deleterious effect on postoperative course, rather than just occurrence of pancreatic fistula. Surgical risk stratification with Braga and WHipple-ABACUS have been proposed and validated. Objective The study aimed at comparing the Braga and WHipple-ABACUS scores for prediction of major complications following pancreaticoduodenectomies. Method This was a prospective observational study at the Tribhuvan University Teaching Hospital from February 2018 to April 2019. After ethical approval, all consecutive 41 patients who underwent pancreaticoduodenectomies were included. Each patient was graded in Braga and WHipple-ABACUS scores. Perioperative events occurring over 30 days were graded as per Clavien -Dindo complications for pancreatic surgery. The predictive value of the scores were assessed using a receiver operating characteristic curve analysis. The categorical data were compared using the Pearson χ2 test or Fisher's exact test. Result Over period of 14 months, total of 41 patients (M:F=2.15:1) with median age of 58 years (range, 21-86) underwent pancreatoduodenectomy. The mean scores were Braga (4.6±3.1) and WHipple-ABACUS (1.8±1.6). Major complications over 30 days were developed in 11 patients with five mortality. There were significant differences in mean values of Braga score (7.0±3.4 vs 3.7±2.6, p-value=0.02) and WHippleABACUS score (3.2±1.8 vs 1.3±1.3, p-value=0.01) in patients with major complications to those without respectively. The area under curves for Braga and WHipple-ABACUS scores were 0.800 and 0.779 respectively. Conclusion Both WHipple-ABACUS and Braga scores are easy to calculate and predict the development of major complications significantly in patients undergoing pancreatoduodenectomy.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Humans ; Middle Aged ; Young Adult ; Pancreatic Fistula/epidemiology ; Pancreatic Fistula/etiology ; Pancreaticoduodenectomy/adverse effects ; Pancreaticoduodenectomy/methods ; Postoperative Complications/epidemiology ; Prospective Studies ; Retrospective Studies ; ROC Curve ; Male ; Female
Language	English
Publishing date	2024-05-01
Publishing country	Nepal
Document type	Observational Study ; Journal Article
ZDB-ID	2257651-4
ISSN	1812-2078 ; 1812-2078
ISSN (online)	1812-2078
ISSN	1812-2078
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Efficient Fluoride Removal by a Fixed-Bed Column of Self-Assembled Zr(IV)-, Fe(III)-, Cu(II)-Complexed Polyvinyl Alcohol Hydrogel Beads.

Mani, Sai Kiran / Bhandari, Rajni

ACS omega

2022 Volume 7, Issue 17, Page(s) 15048–15063

Abstract: Fixed-bed column adsorption studies are performed with metal-complexed polyvinyl alcohol (PVA) hydrogel beads to remove fluoride from groundwater. The fixed-bed column (bed height = 8 ± 0.2 cm) of copper-zirconium-PVA (PCZH), zirconium-PVA (PZH), and ... ...

Abstract	Fixed-bed column adsorption studies are performed with metal-complexed polyvinyl alcohol (PVA) hydrogel beads to remove fluoride from groundwater. The fixed-bed column (bed height = 8 ± 0.2 cm) of copper-zirconium-PVA (PCZH), zirconium-PVA (PZH), and iron-zirconium-PVA (PFZH) hydrogel beads have equilibrium fluoride removal capacities of 17.26 ± 0.05, 31.67 ± 0.05, and 11.84 ± 0.05 mg g
Language	English
Publishing date	2022-04-20
Publishing country	United States
Document type	Journal Article
ISSN	2470-1343
ISSN (online)	2470-1343
DOI	10.1021/acsomega.2c00834
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: A case report on zinc phosphide ingestion resulting to acute pancreatitis.

Bhandari, Rupa / Basnet, Krity

Annals of medicine and surgery (2012)

2022 Volume 78, Page(s) 103859

Abstract: Zinc phosphide is commonly used as a rodenticide and often abused for intentional self harm. For years, Scientist believed that, It gets converted to phosphine gas by hydrolysis in acidic circumference of the stomach upon ingestion. It is absorbed into ... ...

Abstract	Zinc phosphide is commonly used as a rodenticide and often abused for intentional self harm. For years, Scientist believed that, It gets converted to phosphine gas by hydrolysis in acidic circumference of the stomach upon ingestion. It is absorbed into the bloodstream and can affect cardiovascular, respiratory, hepato-biliary hematological and gastrointestinal tract. It also results into electrolyte imbalance and ultimately leads to multi organ failure. We present a case of 46 year-old-male with acute pancreatitis due to zinc phosphide ingestion that was successfully treated conservatively. Acute pancreatitis is a rare complication of zinc phosphide poisoning. It is crucial to identify zinc phosphide as the cause of acute pancreatitis and rule out other factors (like alcohol, drugs, genetics) contributing to acute pancreatitis. Interestingly, patient presents with only mild symptoms of poisoning as metabolic acidosis and abdominal discomfort, acute pancreatitis was incidentally diagnosed through lab investigations and radiographs reports after 3-4 days of ongoing conservative treatment. Management was conservative for acute pancreatitis. This article provides a comprehensive review of management of zinc phosphide poisoning induced acute pancreatitis.
Language	English
Publishing date	2022-05-24
Publishing country	England
Document type	Case Reports
ZDB-ID	2745440-X
ISSN	2049-0801
ISSN	2049-0801
DOI	10.1016/j.amsu.2022.103859
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