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  1. Article ; Online: High burden of hypovitaminosis D among the children and adolescents in South Asia: a systematic review and meta-analysis.

    Siddiqee, Mahbubul H / Bhattacharjee, Badhan / Siddiqi, Umme Ruman / Rahman, Mohammad Meshbahur

    Journal of health, population, and nutrition

    2022  Volume 41, Issue 1, Page(s) 10

    Abstract: Background: Vitamin D is vital for the growth and development of children. While deficiency and/or insufficiency of vitamin D among South Asian children are frequently reported in the literature, the lack of a meta-analysis has left its true extent ... ...

    Abstract Background: Vitamin D is vital for the growth and development of children. While deficiency and/or insufficiency of vitamin D among South Asian children are frequently reported in the literature, the lack of a meta-analysis has left its true extent poorly characterized. In this study, we aimed to conduct a systematic review and perform meta-analyses of the prevalence of hypovitaminosis D among the children of the South Asian countries.
    Methods: Two major electronic search engines (PubMed and Scopus) and one database (Google scholar) were used; original studies, conducted among South Asian children and adolescents and published between 1 January 2001 and 31 December 2019. A random-effect meta-analysis was also performed to calculate the pooled prevalence of hypovitaminosis D followed by subgroup analyses for countries and age groups.
    Results: After applying inclusion and exclusion criteria, a total of 41 studies with a total population size of 18,233 were finally selected. The overall prevalence of hypovitaminosis D was 61% [95% CI: 46% to 71%] with highly significant heterogeneity (I
    Conclusion: This study generates quantitative evidence and specific extent of hypovitaminosis D in the South Asian countries as a public health concern. Being the first systematic review for this region, results from this study will create awareness and will facilitate adopting mitigation strategies by the policymakers and the governments to address this problem.
    MeSH term(s) Adolescent ; Child, Preschool ; Humans ; India/epidemiology ; Infant, Newborn ; Prevalence ; Sri Lanka/epidemiology ; Vitamin D ; Vitamin D Deficiency/epidemiology
    Chemical Substances Vitamin D (1406-16-2)
    Language English
    Publishing date 2022-03-17
    Publishing country Bangladesh
    Document type Journal Article ; Meta-Analysis ; Review ; Systematic Review
    ZDB-ID 2025045-9
    ISSN 2072-1315 ; 1606-0997
    ISSN (online) 2072-1315
    ISSN 1606-0997
    DOI 10.1186/s41043-022-00287-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: High prevalence of vitamin D insufficiency among South Asian pregnant women: a systematic review and meta-analysis

    Siddiqee, Mahbubul Hasan / Bhattacharjee, Badhan / Siddiqi, Umme Ruman / Rahman, Mohammad Meshbhaur

    British journal of nutrition. 20222021 Sept. 28 02, Nov. 28 02, v. 128, no. 6

    2022  

    Abstract: Insufficiency of vitamin D, during pregnancy, is a common cause of various pregnancy-related complications. Despite such insufficiency being frequently reported among South Asian pregnant women, the absence of systematic review and meta-analysis renders ... ...

    Abstract Insufficiency of vitamin D, during pregnancy, is a common cause of various pregnancy-related complications. Despite such insufficiency being frequently reported among South Asian pregnant women, the absence of systematic review and meta-analysis renders the true extent of this problem being poorly characterised. In this systematic review, three main databases (PubMed, Scopus and Google Scholar) were searched for original studies. We included original studies published between 1January 2001 to 31 December 2019, conducted on pregnant women who lived in South Asian countries and reported the prevalence of vitamin D insufficiency among the study participants. Twenty studies with a total of 7804 participants from four South Asian countries finally met our selection criteria. Overall pooled prevalence of insufficiency was 65 % (95 % CI: 51 %, 78 %) with a significant heterogeneity (I² = 99·37 %; P = 0·00). The average level of vitamin D ranged from 9 ng/ml to 24·86 ng/ml with a weighted mean of 16·37 ng/ml (weighted standard deviation 7·13 ng/ml). The highest prevalence of insufficiency was found in Pakistan (76 %) followed by India (67 %), Bangladesh (64 %) and Nepal (14 %). Results obtained in this study suggest that vitamin D insufficiency is highly prevalent among South Asian pregnant women. Being the first systematic review in this region, findings from this study will help the future studies and strengthen the evidence for policymakers to develop effective mitigation strategies.
    Keywords meta-analysis ; pregnancy ; standard deviation ; systematic review ; Bangladesh ; India ; Nepal ; Pakistan
    Language English
    Dates of publication 2022-0928
    Size p. 1118-1129.
    Publishing place Cambridge University Press
    Document type Article
    ZDB-ID 280396-3
    ISSN 1475-2662 ; 0007-1145
    ISSN (online) 1475-2662
    ISSN 0007-1145
    DOI 10.1017/S0007114521004360
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: High prevalence of vitamin D deficiency among the South Asian adults: a systematic review and meta-analysis.

    Siddiqee, Mahbubul H / Bhattacharjee, Badhan / Siddiqi, Umme Ruman / MeshbahurRahman, Mohammad

    BMC public health

    2021  Volume 21, Issue 1, Page(s) 1823

    Abstract: Background: Vitamin-D deficiency is linked to a wide range of chronic and infectious diseases. Body of literature suggested that the prevalence of this deficiency can have geographical variation. Although vitamin D deficiency is frequently reported in ... ...

    Abstract Background: Vitamin-D deficiency is linked to a wide range of chronic and infectious diseases. Body of literature suggested that the prevalence of this deficiency can have geographical variation. Although vitamin D deficiency is frequently reported in the South Asian population, the scarcity of systematic reviews and meta-analysis means the true extent of the disease and the underlying factors causing it are poorly characterized.
    Methods: A systematic search was performed using two databases (PubMed and Scopus) and one search engine (Google Scholar) for original studies on the South Asian population (published from January 1, 2001, to December 31, 2019). Following the search, a random effect meta-analysis was performed to calculate population-level weighted average, the pooled prevalence of deficiency, and heterogeneity of vitamin D among different countries and genders; in addition to South Asia as a whole.
    Results: Our study, based on our selection criteria was narrowed down to a total of 44,717 participants; which spanned over 65 studies from five South Asian countries. Overall, the pooled prevalence of deficiency was 68% [95% CI: 64 to 72%] with significant heterogeneity (I
    Conclusion: Our findings reveal highly prevalent and variable vitamin D deficiency among the adults of different South Asian countries. Findings from this review would be helpful to generate hypotheses and explore the factors affecting the inter-country variability, alongside strengthening evidence for governments to prioritize mitigation strategies in this region.
    MeSH term(s) Adult ; Female ; Humans ; India ; Male ; Prevalence ; Sri Lanka ; Vitamin D ; Vitamin D Deficiency/epidemiology
    Chemical Substances Vitamin D (1406-16-2)
    Language English
    Publishing date 2021-10-09
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ISSN 1471-2458
    ISSN (online) 1471-2458
    DOI 10.1186/s12889-021-11888-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: High prevalence of vitamin D insufficiency among South Asian pregnant women: a systematic review and meta-analysis.

    Siddiqee, Mahbubul Hasan / Bhattacharjee, Badhan / Siddiqi, Umme Ruman / Rahman, Mohammad Meshbhaur

    The British journal of nutrition

    2021  Volume 128, Issue 6, Page(s) 1118–1129

    Abstract: Insufficiency of vitamin D, during pregnancy, is a common cause of various pregnancy-related complications. Despite such insufficiency being frequently reported among South Asian pregnant women, the absence of systematic review and meta-analysis renders ... ...

    Abstract Insufficiency of vitamin D, during pregnancy, is a common cause of various pregnancy-related complications. Despite such insufficiency being frequently reported among South Asian pregnant women, the absence of systematic review and meta-analysis renders the true extent of this problem being poorly characterised. In this systematic review, three main databases (PubMed, Scopus and Google Scholar) were searched for original studies. We included original studies published between 1January 2001 to 31 December 2019, conducted on pregnant women who lived in South Asian countries and reported the prevalence of vitamin D insufficiency among the study participants. Twenty studies with a total of 7804 participants from four South Asian countries finally met our selection criteria. Overall pooled prevalence of insufficiency was 65 % (95 % CI: 51 %, 78 %) with a significant heterogeneity (I
    MeSH term(s) Humans ; Female ; Pregnancy ; Vitamin D ; Pregnant Women ; Prevalence ; South Asian People ; Vitamins ; Pregnancy Complications/epidemiology ; Vitamin D Deficiency/epidemiology
    Chemical Substances Vitamin D (1406-16-2) ; Vitamins
    Language English
    Publishing date 2021-11-02
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 280396-3
    ISSN 1475-2662 ; 0007-1145
    ISSN (online) 1475-2662
    ISSN 0007-1145
    DOI 10.1017/S0007114521004360
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Risk perception of sun exposure and knowledge of vitamin D among the healthcare providers in a high-risk country: a cross-sectional study.

    Siddiqee, Mahbubul H / Bhattacharjee, Badhan / Hasan, Mahbub / Shojon, Mohammad / Hassan, Mehedi / Rouf, Rashawan Raziur / Siddiqi, Umme Raihan / Rabbi, Fazlay / Siddiqi, Umme Ruman

    BMC medical education

    2023  Volume 23, Issue 1, Page(s) 46

    Abstract: Background: High levels of vitamin D deficiency are commonly reported even in regions with abundant sunshine. This necessitates a comprehensive understanding of the determinants that influence sun exposure practices. As the primary source of health- ... ...

    Abstract Background: High levels of vitamin D deficiency are commonly reported even in regions with abundant sunshine. This necessitates a comprehensive understanding of the determinants that influence sun exposure practices. As the primary source of health-related knowledge for the general public, the attitude of the healthcare professionals towards sunlight and their awareness related to vitamin D deficiency can be critical in this regard.
    Methods: A cross-sectional survey was conducted among 2,242 physicians, intern doctors, and senior medical students in Bangladesh from October 2019 to February 2020. A pre-tested structured questionnaire (containing twelve close-ended questions) was used. The perceptions of health risks due to sun exposure, and basic knowledge of the physiological and epidemiological aspects of vitamin D deficiency were tested.
    Results: An overall negative attitude towards sunlight in the context of Bangladesh was highlighted - 68% participants thought regular sun exposure would be harmful or very harmful; 26% thought the level of UV radiation was very high; 44% recommended using sunscreen always; skin burns, heat stroke, and cancer were selected as potential consequences of regular sun exposure by 45%, 21%, and 30% respondents respectively. Overall knowledge regarding vitamin D deficiency appeared to be biased towards bone health; other symptoms and associated illnesses not having obvious link to Calcium-metabolism were identified much lesser frequently. Furthermore, 'sunrise to 10 am' was identified as the best time to get vitamin D by 69% participants; 60% believed < 30 min of weekly sun exposure would be sufficient for the Bangladeshi population; an only 33% identified that prevalence of vitamin D insufficiency in Bangladesh would be 50% or more. Taking vitamin D-rich food was suggested by more respondents over regular sun exposure (43% vs. 33%) as more effective remedial strategy to curb vitamin D deficiency in Bangladesh.
    Conclusion: In addition to highlighting some crucial knowledge gaps, results from this study provides a comprehensive baseline dataset for knowledge and attitude regarding the public health aspects of vitamin D deficiency among the healthcare providers in Bangladesh, which would be generalizable to other countries with similar socio-demographic context, and will facilitate taking more effective policies worldwide.
    MeSH term(s) Humans ; Vitamin D ; Cross-Sectional Studies ; Sunlight/adverse effects ; Health Knowledge, Attitudes, Practice ; Vitamin D Deficiency/epidemiology ; Vitamin D Deficiency/prevention & control ; Health Personnel ; Perception
    Chemical Substances Vitamin D (1406-16-2)
    Language English
    Publishing date 2023-01-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2044473-4
    ISSN 1472-6920 ; 1472-6920
    ISSN (online) 1472-6920
    ISSN 1472-6920
    DOI 10.1186/s12909-023-04001-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Age-related risk factors and severity of SARS-CoV-2 infection: a systematic review and meta-analysis.

    Rahman, Mohammad Meshbahur / Bhattacharjee, Badhan / Farhana, Zaki / Hamiduzzaman, Mohammad / Chowdhury, Muhammad Abdul Baker / Hossain, Mohammad Sorowar / Siddiqee, Mahbubul H / Islam, Md Ziaul / Raheem, Enayetur / Uddin, Md Jamal

    Journal of preventive medicine and hygiene

    2021  Volume 62, Issue 2, Page(s) E329–E371

    Abstract: Objectives: We aimed to estimate the prevalence of reported symptoms and comorbidities, and investigate the factors associated with age of the SARS-CoV-2 infected patients.: Methods: We performed a systematic review with meta-analysis (PROSPERO ... ...

    Abstract Objectives: We aimed to estimate the prevalence of reported symptoms and comorbidities, and investigate the factors associated with age of the SARS-CoV-2 infected patients.
    Methods: We performed a systematic review with meta-analysis (PROSPERO registration: CRD42020182677) where the databases (PubMed, SCOPUS, EMBASE, WHO, Semantic Scholar, and COVID-19 Primer) were searched for clinical studies published from January to April, 2020. Initially, the pooled prevalence of symptoms and comorbidity of COVID-19 patients were estimated using random effect model and the age -related factors were identified performing multivariate analysis [factor analysis].
    Results: Twenty-nine articles with 4,884 COVID-19 patients were included in this study. Altogether, we found 33 symptoms and 44 comorbidities where the most frequent 19 symptoms and 11 comorbidities were included in the meta-analysis. The fever (84%), cough/dry cough (61%), and fatigue/weakness (42%) were found more prevalent while acute respiratory distress syndrome, hypertension and diabetes were the most prevalent comorbid condition. The factor analysis showed positive association between a cluster of symptoms and comorbidities with patients' age. The symptoms comprising fever, dyspnea/shortness of breath, nausea, vomiting, abdominal pain, dizziness, anorexia and pharyngalgia; and the comorbidities including diabetes, hypertension, coronary heart disease, COPD/lung disease and ARDS were the factors positively associated with COVID-19 patient's age.
    Conclusion: As an unique effort, this study found a group of symptoms (fever, dyspnea/shortness of breath, nausea, vomiting, abdominal pain, dizziness, anorexia and pharyngalgia) and comorbidities (diabetes, hypertension, coronary heart disease, COPD/lung disease and ARDS), associated with the age of COVID-19 infected patients.
    MeSH term(s) Age Factors ; Aged ; Aged, 80 and over ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/mortality ; Comorbidity ; Female ; Fever/etiology ; Humans ; Male ; Middle Aged ; Pandemics ; Prevalence ; Risk Factors ; SARS-CoV-2
    Language English
    Publishing date 2021-07-30
    Publishing country Italy
    Document type Journal Article ; Meta-Analysis ; Review ; Systematic Review
    ZDB-ID 1102926-2
    ISSN 2421-4248 ; 1121-2233
    ISSN (online) 2421-4248
    ISSN 1121-2233
    DOI 10.15167/2421-4248/jpmh2021.62.2.1946
    Database MEDical Literature Analysis and Retrieval System OnLINE

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