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  1. Article: Cardio-Thyrotoxicosis Syndrome: A Review of Thyrotoxic Cardiovascular Disease.

    Bhattad, Pradnya Brijmohan / Roumia, Mazen

    Cureus

    2023  Volume 15, Issue 4, Page(s) e37659

    Abstract: Thyrotoxicosis, an endocrine disorder characterized by elevated serum thyroid hormone levels of tri-iodothyronine (T3) and/or thyroxine (T4), can impact cardiovascular health in several ways. The cardiovascular system is often severely targeted by the ... ...

    Abstract Thyrotoxicosis, an endocrine disorder characterized by elevated serum thyroid hormone levels of tri-iodothyronine (T3) and/or thyroxine (T4), can impact cardiovascular health in several ways. The cardiovascular system is often severely targeted by the thyrotoxic state, and the term "Cardio-thyrotoxic syndrome" has been proposed to encompass the various cardiovascular disease states resulting from thyrotoxicosis. In this review, we discuss various cardiovascular disorders resulting from the effects of thyrotoxicosis. It is important to keep a high index of suspicion for thyroid disorder in the setting of new atrial fibrillation, heart failure, and tachycardia-induced cardiomyopathy. Management of cardio-thyrotoxicosis involves control of heart rate and blood pressure and treatment of acute cardiovascular complications. Thyroid-specific therapy to achieve a euthyroid state will not only improve but even potentially reverse cardiovascular abnormalities.
    Language English
    Publishing date 2023-04-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.37659
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Cardiovascular Remodeling in Chronic Mineralocorticoid Excess.

    Bhattad, Pradnya Brijmohan / Roumia, Mazen

    Cureus

    2023  Volume 15, Issue 6, Page(s) e40753

    Abstract: Primary hyperaldosteronism typically leads to resistant hypertension, hypokalemia, and metabolic alkalosis. Excess aldosterone secretion by the adrenal glands may lead to heart failure with preserved ejection fraction. Potassium-sparing diuretics and ... ...

    Abstract Primary hyperaldosteronism typically leads to resistant hypertension, hypokalemia, and metabolic alkalosis. Excess aldosterone secretion by the adrenal glands may lead to heart failure with preserved ejection fraction. Potassium-sparing diuretics and aldosterone antagonists directed to lower excess aldosterone levels may help treat the associated heart failure and lead to control of blood pressure, resulting in improved outcomes. We report a case of a 55-year-old male with poorly controlled hypertension and newly symptomatic heart failure with preserved ejection fraction in the setting of excess aldosterone activity and an adrenal adenoma suggesting primary aldosteronism-induced diastolic heart failure. The biochemical evaluation revealed elevated plasma aldosterone concentrations with low plasma renin activity, diuretic-induced hypokalemia, and metabolic alkalosis. A progressively enlarging left adrenal adenoma was found on abdominal imaging along with resistant hypertension despite the use of multiple antihypertensive medications. Medical management targeted to lower excess aldosterone levels with the use of aldosterone antagonists helped us achieve better blood pressure control and resolution of symptoms of diastolic dysfunction. Treating the underlying pathology helped us improve overt heart failure and may suggest that goal-directed therapy towards the inciting factors may potentially lead to a path to reverse the heart failure symptoms clinically.
    Language English
    Publishing date 2023-06-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.40753
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Rumpel-Leede phenomenon post-transradial cardiac catheterization: a rare clinical entity.

    Bhattad, Pradnya Brijmohan / Sharma, Nitish Kumar / Ramsaran, Eddison

    Coronary artery disease

    2024  Volume 35, Issue 3, Page(s) 259

    Language English
    Publishing date 2024-01-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 1047268-x
    ISSN 1473-5830 ; 0954-6928
    ISSN (online) 1473-5830
    ISSN 0954-6928
    DOI 10.1097/MCA.0000000000001322
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Empowering Patients: Promoting Patient Education and Health Literacy.

    Bhattad, Pradnya Brijmohan / Pacifico, Luigi

    Cureus

    2022  Volume 14, Issue 7, Page(s) e27336

    Abstract: Patients are generally keen to understand and obtain more information about their medical conditions. There exists a need to develop updated and thorough yet concise patient education handouts and to encourage healthcare providers (HCPs) to use uniform ... ...

    Abstract Patients are generally keen to understand and obtain more information about their medical conditions. There exists a need to develop updated and thorough yet concise patient education handouts and to encourage healthcare providers (HCPs) to use uniform patient education methods. A thorough review of literature on patient education material was performed prior to starting the study. A comparison with different resources regarding the appropriateness of patient education was done. Educating HCPs to effectively use patient educational materials incorporated into the electronic health record system, including electronic methods, such as the use of a patient portal, to help educate patients.  Strategies were formulated to reduce the amount of processing and attending time required for fetching appropriate materials and lead to fast, efficient, and effective patient education. To improve the physical and psychosocial wellbeing of a patient, personalized patient education handouts, in addition to verbal education by the HCPs, augment the betterment of patient care via shared decision making and by improving patient satisfaction and health literacy.
    Language English
    Publishing date 2022-07-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.27336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Anomalous Origin of the Left Circumflex Coronary Artery: Approach in Acute Coronary Syndrome.

    Bhattad, Pradnya Brijmohan / Ramsaran, Eddison

    Cureus

    2022  Volume 14, Issue 9, Page(s) e29330

    Abstract: Coronary artery anomalies are congenital and relatively uncommon. Anomalous origin of the left circumflex artery from the right is a relatively common congenital coronary variant and is usually considered benign in itself. The presence of an anomalous ... ...

    Abstract Coronary artery anomalies are congenital and relatively uncommon. Anomalous origin of the left circumflex artery from the right is a relatively common congenital coronary variant and is usually considered benign in itself. The presence of an anomalous coronary artery may pose challenges in engaging the anomalous vessel, and prompt recognition of an anomalous coronary artery is important to allow for appropriate coronary interventions. Here, we describe the case of a patient who presented with cocaine-induced acute ST-segment elevation myocardial infarction and was incidentally noted to have an anomalous left circumflex coronary artery arising from the right coronary cusp with a relatively uncommon variant of the anomalous origin. We believe that this case in itself is rare and discusses the approach to anomalous coronaries in an acute coronary syndrome presentation which is unique and rare in the existing literature regarding coronary anomalies.
    Language English
    Publishing date 2022-09-19
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.29330
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Building Body With Anabolics Is Weakening the Heart: Anabolic Steroid Induced Cardiomyopathy.

    Bhattad, Pradnya Brijmohan / Roumia, Mazen

    Cureus

    2022  Volume 14, Issue 7, Page(s) e26579

    Abstract: Anabolic steroid (AS) use is common in young males, with several reports of various adverse cardiovascular events in the users of AS. We present a unique case of a young male with no other risk factors who developed dilated cardiomyopathy secondary to ... ...

    Abstract Anabolic steroid (AS) use is common in young males, with several reports of various adverse cardiovascular events in the users of AS. We present a unique case of a young male with no other risk factors who developed dilated cardiomyopathy secondary to abuse of AS. The exact mechanism by which AS leads to cardiomyopathy is not very well understood. No specific guidelines have been developed yet with regard to the management of AS-induced cardiomyopathy currently. Adverse events from AS must be promoted to increase awareness in the general and medical population.
    Language English
    Publishing date 2022-07-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.26579
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Bradycardia-Induced Torsades de Pointes in Atrioventricular Block.

    Bhattad, Pradnya Brijmohan / Jha, Anil / Wholey, Richard

    Cureus

    2023  Volume 15, Issue 4, Page(s) e37507

    Abstract: Bradycardia is known to prolong QT interval. Persistent bradycardia and high-grade atrioventricular (AV) block may lead to persistently prolonged QTc interval with a risk for life-threatening ventricular arrhythmias, which needs addressing the underlying ...

    Abstract Bradycardia is known to prolong QT interval. Persistent bradycardia and high-grade atrioventricular (AV) block may lead to persistently prolonged QTc interval with a risk for life-threatening ventricular arrhythmias, which needs addressing the underlying cause. We present the case of a patient with persistent sinus bradycardia with a high-grade AV block leading to persistently prolonged QTc without any reversible etiology that resulted in torsades de pointes. The underlying treatment involved shortening the QTc by increasing the heart rate to prevent any further episodes of polymorphic ventricular tachycardia.
    Language English
    Publishing date 2023-04-12
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.37507
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Atrioventricular Block: An Unusual Presentation of Overactive Thyroid.

    Bhattad, Pradnya Brijmohan / Yukselen, Zeynep / Filiberti, Allen

    Cureus

    2023  Volume 15, Issue 2, Page(s) e35141

    Abstract: The clinical features of hyperthyroidism are varied, but bradyarrhythmia and atrioventricular (AV) block are typically not reported in hyperthyroid patients. We present here a case of primary hyperthyroidism with symptomatic high-grade AV block as the ... ...

    Abstract The clinical features of hyperthyroidism are varied, but bradyarrhythmia and atrioventricular (AV) block are typically not reported in hyperthyroid patients. We present here a case of primary hyperthyroidism with symptomatic high-grade AV block as the sole presenting feature of hyperthyroidism without any obvious precipitating factors for thyroid disease or AV block. This case highlights a rare presentation of high-grade AV block with the risk of progression to complete AV block as a complication of an untreated overactive thyroid.
    Language English
    Publishing date 2023-02-18
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.35141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Left Pulmonary Artery Aneurysm: A Post-stenotic Pulmonary Aneurysm Related to Pulmonary Valve Stenosis.

    Bhattad, Pradnya Brijmohan / Yukselen, Zeynep / Bhasin, Mohit / Roumia, Mazen

    Cureus

    2023  Volume 15, Issue 2, Page(s) e34836

    Abstract: Aneurysms of the pulmonary artery are uncommon vascular pathologies that are associated with congenital structural cardiac anomalies, pulmonary hypertension, vasculitis, neoplasm, iatrogenic, and infection. PAAs are commonly asymptomatic and accidentally ...

    Abstract Aneurysms of the pulmonary artery are uncommon vascular pathologies that are associated with congenital structural cardiac anomalies, pulmonary hypertension, vasculitis, neoplasm, iatrogenic, and infection. PAAs are commonly asymptomatic and accidentally diagnosed, however, if symptomatic, clinical features are generally non-specific and depend on the etiology of PAA. CT pulmonary angiography remains the gold standard imaging modality and other diagnostic imaging tests include transthoracic echocardiography and right heart catheterization. Definitive treatment of PAA is surgery, however, conservative management with close monitoring should be practiced in patients with poor surgical candidates or surgery is unlikely to improve survival. Here, we report a case of pulmonary artery aneurysm secondary to congenital pulmonary valve stenosis as well as a brief review of the literature regarding pulmonary artery aneurysms.
    Language English
    Publishing date 2023-02-10
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.34836
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Constrictive Pericarditis: A Commonly Missed Cause of Treatable Diastolic Heart Failure.

    Bhattad, Pradnya Brijmohan / Jain, Vinay

    Cureus

    2020  Volume 12, Issue 5, Page(s) e8024

    Abstract: Constrictive pericarditis arises as a result of the fibrous thickening of the pericardium due to chronic inflammatory changes from various injuries. Increased pulmonary and systemic venous pressures manifest clinical features of left and right heart ... ...

    Abstract Constrictive pericarditis arises as a result of the fibrous thickening of the pericardium due to chronic inflammatory changes from various injuries. Increased pulmonary and systemic venous pressures manifest clinical features of left and right heart failure. Idiopathic or post-viral pericarditis is the most common cause followed by postpericardiotomy, radiation-induced causes. Right-sided heart failure symptoms predominate over left-sided heart failure symptoms due to the equalization of pressures. No single diagnostic test can provide a definitive diagnosis or evidence of constrictive pericarditis. Medical management is difficult for constrictive pericarditis. The treatment of choice for constrictive pericarditis is pericardiectomy.
    Language English
    Publishing date 2020-05-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.8024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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