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  1. Article ; Online: Hookworm infestation as a rare cause of melaena in tropics: A case report.

    Pandit, Narendra / Bhattarai, Sameer / Nalbo, Dinesh / Yadav, Sanjay

    Tropical doctor

    2024  Volume 54, Issue 2, Page(s) 191–192

    Abstract: Melaena due to hookworm infestation is a rare clinical presentation. It usually presents with symptoms of iron-deficiency anaemia owing to slow blood loss. Here we present a case of 45-year male who presented with a one-year history of intermittent ... ...

    Abstract Melaena due to hookworm infestation is a rare clinical presentation. It usually presents with symptoms of iron-deficiency anaemia owing to slow blood loss. Here we present a case of 45-year male who presented with a one-year history of intermittent melena requiring multiple blood transfusions. Preliminary endoscopies at different centres were normal. The presence of hookworm in the duodenum was only detected on repeat upper endoscopy as the cause of blood loss, and treatment with albendazole was successful in curing the patient.
    MeSH term(s) Animals ; Humans ; Male ; Melena/etiology ; Ancylostomatoidea ; Hookworm Infections/complications ; Hookworm Infections/diagnosis ; Hookworm Infections/drug therapy ; Duodenum ; Anemia, Iron-Deficiency
    Language English
    Publishing date 2024-01-21
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 193169-6
    ISSN 1758-1133 ; 0049-4755
    ISSN (online) 1758-1133
    ISSN 0049-4755
    DOI 10.1177/00494755231226356
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Resectability and prognosis of gallbladder cancer: a cross-sectional study of 100 cases from a tertiary care centre of Eastern Nepal.

    Pandit, Narendra / Neupane, Durga / Nalbo, Dinesh / Bhattarai, Sameer / Deo, Kunal B / Jaiswal, Lokesh S / Adhikary, Shailesh

    Annals of medicine and surgery (2012)

    2023  Volume 85, Issue 5, Page(s) 1755–1760

    Abstract: Gallbladder cancer (GBC) is the fifth most common neoplasm of the digestive tract and has an overall incidence of 3 per 100 000 people. Only 15-47% of the preoperatively known GBC are suitable for resection. The objective of the study was to investigate ... ...

    Abstract Gallbladder cancer (GBC) is the fifth most common neoplasm of the digestive tract and has an overall incidence of 3 per 100 000 people. Only 15-47% of the preoperatively known GBC are suitable for resection. The objective of the study was to investigate the resectability and prognosis of GBC patients.
    Materials and methods: It is a prospective observational study including all cases of primary cancers of the gallbladder in the Department of Surgical Gastroenterology at a tertiary care center over the period from January 2014 to December 2019. The primary endpoint was resectability and overall survival.
    Results: During the study period, 100 patients with GBC were reported. The mean age at the time of diagnosis was 52.5 years, with a female predominance (67%). The curative intent resection (radical cholecystectomy) was possible in 30 (30%) patients; while 18 (18%) required palliative surgical treatment. The overall survival of the entire group was 9 months; while those patients who underwent surgery with curative intent had a median overall survival of 28 months after a median follow-up of 42 months.
    Conclusion: This study found that only one-third of patients achieve radical surgery with curative intent. Overall, the prognosis of patients is poor with a median survival of less than a year due to the advanced stage disease. Multimodality treatment, screening ultrasound, and neo-/adjuvant therapy may improve survival.
    Language English
    Publishing date 2023-04-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2745440-X
    ISSN 2049-0801
    ISSN 2049-0801
    DOI 10.1097/MS9.0000000000000699
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Characterization of large wood and its relationship to pool formation and macroinvertebrate metrics in southeastern coastal plain streams, USA

    Stewart, Paul M. / Bhattarai, Sameer / Mullen, Michael W. / Metcalf, Christopher K. / Reátegui-Zirena, Evelyn G.

    Journal of freshwater ecology

    Volume v. 27,, Issue no. 3

    Abstract: Large wood has important structural and functional roles in streams but there is little information on large wood dynamics in the southeastern coastal plains, USA. In this study, we surveyed 35 streams in the Choctawhatchee River watershed of ... ...

    Abstract Large wood has important structural and functional roles in streams but there is little information on large wood dynamics in the southeastern coastal plains, USA. In this study, we surveyed 35 streams in the Choctawhatchee River watershed of southeastern Alabama. These streams were broadly classified into three categories based on land use: urban, forest, and mixed (agriculture plus forest). The number, volume, and functions of large wood were quantified. Pool number, pool spacing, and drainage areas of each stream were measured along with assessment of macroinvertebrate assemblages. Large wood number and volume plus pool number and spacing were used to examine the relationship among large wood characteristics and functions, pool characteristics, drainage area, and attributes of macroinvertebrate assemblages including species richness, Shannon–Wiener diversity (H′), number of Ephemeroptera, Plecoptera, and Trichoptera (EPT) species, and the Invertebrate Community Index (ICI – a multimetric index that reflects biological integrity of streams). There were significant differences in large wood number and volume among the three different stream categories, with highest large wood number and volume in forest streams. More pools and storage sites for sediment and organic matter were found in forest streams than urban and mixed streams. Large wood appeared to be positively related to macroinvertebrate assemblages, as species richness, H′ , EPT, and ICI were generally higher in forest streams as compared to those of urban and mixed streams. The outcome of this study suggests that large wood contributes to the physical and biological complexity of streams in the southeastern coastal plain streams of the USA.
    Keywords forests ; wood ; Plecoptera ; drainage ; macroinvertebrates ; watersheds ; organic matter ; rivers ; coastal plains ; Ephemeroptera ; sediments ; streams ; land use ; species diversity ; Trichoptera
    Language English
    Document type Article
    ISSN 2156-6941
    Database AGRIS - International Information System for the Agricultural Sciences and Technology

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