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Book ; Online: Towards a New Paradigm for Statistical Evidence

Bhatti, Muhammad Ishaq / Kim, Jae H.

2021

Keywords	Humanities ; p-value ; Bayesian ; model specification ; model testing ; reporting results (p-values) ; replications ; equivalence ; minimum-effect ; non-inferiority ; point-null hypothesis testing ; zero probability paradox ; t-statistic ; pretest estimator ; model averaging ; a priori procedure ; null hypothesis significance testing ; confidence intervals ; p-values ; estimation ; hypothesis testing ; replication crisis ; profit maximization ; market failure ; teaching of econometrics ; regression analysis ; economics pedagogy ; n/a
Size	1 electronic resource (104 pages)
Publisher	MDPI - Multidisciplinary Digital Publishing Institute
Publishing place	Basel, Switzerland
Document type	Book ; Online
Note	English ; Open Access
HBZ-ID	HT021291852
ISBN	9783036508832 ; 303650883X
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article: Navigating the Diagnosis and Treatment of Astroblastoma: A Pediatric Case Report.

Khan, Haysum / Afreen, Mahrukh / Khan, Abdullah / Ali Malik, Saif / Bhatti, Mohammad Imran

Cureus

2024 Volume 16, Issue 2, Page(s) e54901

Abstract: Astroblastoma, a rare glial tumor of the central nervous system, presents diagnostic and therapeutic challenges due to its low incidence and variable clinical presentations. In this case study, we present the case of an 11-year-old boy with high-grade ... ...

Abstract	Astroblastoma, a rare glial tumor of the central nervous system, presents diagnostic and therapeutic challenges due to its low incidence and variable clinical presentations. In this case study, we present the case of an 11-year-old boy with high-grade astroblastoma, highlighting the complexities in diagnosis and treatment. The clinical presentation initially involved right-sided motor weakness, which, after undergoing a brain MRI, revealed a large solid cystic mass in the left parietal lobe. Histopathological examination after undergoing surgery confirmed an astroblastoma with high-grade features, characterized by increased cellularity and high mitotic activity. Immunostaining patterns supported the glial origin of the tumor. Gross total resection remains the primary approach for its treatment, but adjuvant therapies for high-grade astroblastomas are still evolving, offering potential life-changing possibilities for the future. Due to its rarity, collecting sufficient data to develop an effective treatment protocol for this uncommon tumor is very challenging. This case underscores the importance of combined efforts and ongoing research to effectively navigate the diagnosis and treatment of astroblastoma.
Language	English
Publishing date	2024-02-25
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.54901
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Corporate vulnerability in the US and China during COVID-19: A machine learning approach.

Khan, Muhammad Asif / Segovia, Juan E Trinidad / Bhatti, M Ishaq / Kabir, Asif

Journal of economic asymmetries

2023 Volume 27, Page(s) e00302

Abstract: The impact of COVID-19 on stock market dynamics and other macroeconomic indicators has been extensively researched. However, the question of how it affects corporate vulnerability has received less attention. This article aims to fill this gap by ... ...

Abstract	The impact of COVID-19 on stock market dynamics and other macroeconomic indicators has been extensively researched. However, the question of how it affects corporate vulnerability has received less attention. This article aims to fill this gap by examining the implications of COVID-19 on corporate vulnerability in the United States (US) and China, using daily data from January 2020 to December 2021. The empirical results of cointegration analysis demonstrate that COVID-19 considerably worsen corporate vulnerabilities in the long-term in the US and in the short-term in China. Additionally, non-linear results demonstrate long-run asymmetries in the US and short-run asymmetries in China, confirming the accuracy of error prediction and suggesting that US corporations are more exposed to COVID-19-induced risks. The channels through which COVID-19 may affect corporate vulnerability include changes in consumer behavior and demand, disruptions in supply chains, financial stress, government policies and regulations, and changes in the competitive landscape. This study sheds light on the effects of the COVID-19 pandemic on corporate vulnerability in the US and China, revealing regulatory implications that may necessitate greater government involvement, managerial implications that emphasize risk management and contingency planning, and social implications that highlight the importance of prioritizing stakeholder welfare and embracing digital transformation.
Language	English
Publishing date	2023-04-10
Publishing country	Canada
Document type	Journal Article
ZDB-ID	2571389-9
ISSN	1703-4949
ISSN	1703-4949
DOI	10.1016/j.jeca.2023.e00302
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Acute presentation of Chiari malformation type I in adulthood with arm swelling, a case report and literature review.

Fallatah, Bassam / Ben Ali, Haitham / Bhatti, Muhammad Imran / Bashir, Shahid

Spinal cord series and cases

2023 Volume 9, Issue 1, Page(s) 27

Abstract: Introduction: Chiari malformation type I (CM-I) with cervicothoracic syringomyelia can progress slowly this condition which is very common in clinical practice, particularly in children.: Case presentation: Patients typically present with chronic ... ...

Abstract	Introduction: Chiari malformation type I (CM-I) with cervicothoracic syringomyelia can progress slowly this condition which is very common in clinical practice, particularly in children. Case presentation: Patients typically present with chronic complaints, including headache, dizziness, and numbness, although are few reports in the literature describing pediatric patients who developed acute neurological deficits caused by CM-I. Here, we report an unusual presentation of this condition; the patient presented with sudden onset arm swelling with no precipitating factors that could explain the diagnosis. Discussion: This is an illustrated case report and literature review. The patient's condition improved post-operatively; in terms of arm and hand swelling which resolved, but he still complained of persistent numbness on a follow-up visit.
MeSH term(s)	Child ; Humans ; Male ; Arm ; Arnold-Chiari Malformation/diagnosis ; Arnold-Chiari Malformation/diagnostic imaging ; Edema/etiology ; Hypesthesia/complications ; Syringomyelia/complications ; Syringomyelia/diagnostic imaging ; Syringomyelia/surgery ; Adult
Language	English
Publishing date	2023-07-06
Publishing country	England
Document type	Review ; Case Reports ; Journal Article
ISSN	2058-6124
ISSN (online)	2058-6124
DOI	10.1038/s41394-023-00583-5
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Raising capital amid economic policy uncertainty: an empirical investigation.

Ashraf, Dawood / Khawaja, Mohsin / Bhatti, M Ishaq

Financial innovation

2022 Volume 8, Issue 1, Page(s) 74

Abstract: This paper investigates how economic policy uncertainty affects firms' frequency and their choice of financial instruments to raise capital. By applying a three-step sequential framework over a sample of 6834 publicly listed US non-financial firms, we ... ...

Abstract	This paper investigates how economic policy uncertainty affects firms' frequency and their choice of financial instruments to raise capital. By applying a three-step sequential framework over a sample of 6834 publicly listed US non-financial firms, we find that during periods of high economic uncertainty, firms raise capital more frequently with a preference toward debt financing. The empirical findings suggest that firms prefer debt financing over equity financing to avoid ownership dilution and high equity premia. The rise in leverage during periods of high economic uncertainty highlights the importance of scrutinizing policy tools used to stabilize the economy during such times.
Language	English
Publishing date	2022-08-15
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2824759-0
ISSN	2199-4730 ; 2199-4730
ISSN (online)	2199-4730
ISSN	2199-4730
DOI	10.1186/s40854-022-00379-w
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Article ; Online: Computational data of molybdenum disulfide/graphene bilayer heterojunction under strain.

Dimakis, Nicholas / Gupta, Sanju / Wadud, Razeen / Bhatti, Muhammad I

Data in brief

2022 Volume 42, Page(s) 108054

Abstract: The data presented in this paper refer to the research article "Dry and Hydrated Defective Molybdenum Disulfide/Graphene Bilayer Heterojunction Under Strain for Hydrogen Evolution from Water Splitting: A First-principle Study". Here, we present the ... ...

Abstract	The data presented in this paper refer to the research article "Dry and Hydrated Defective Molybdenum Disulfide/Graphene Bilayer Heterojunction Under Strain for Hydrogen Evolution from Water Splitting: A First-principle Study". Here, we present the Density Functional Theory (DFT) data used to generate optimal geometries and electronic structure for the MoS
Language	English
Publishing date	2022-03-13
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2786545-9
ISSN	2352-3409 ; 2352-3409
ISSN (online)	2352-3409
ISSN	2352-3409
DOI	10.1016/j.dib.2022.108054
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: How fear of intimacy affects infertile men's neuropsychological functioning through mental toughness.

Hassan, Sajid / Bhatti, Mazhar Iqbal / Habib, Shazia / Fatima, Sidra / Bhader, Sher / Khan, Nazeer Hussain / Jiang, Enshe

Frontiers in psychiatry

2023 Volume 14, Page(s) 1049008

Abstract: Objective: There is a significant need in Pakistan to investigate the psychological effects of infertility on the mental health of infertile men. The current study examined how fear of intimacy affects neuropsychological impairment and evaluated its ... ...

Abstract	Objective: There is a significant need in Pakistan to investigate the psychological effects of infertility on the mental health of infertile men. The current study examined how fear of intimacy affects neuropsychological impairment and evaluated its relationship to other variables including quality of life and mental toughness. Method: An analytical cross-sectional study was carried out on infertile male patients in various healthcare settings in Punjab, Pakistan. The participants were recruited using a non-probability (purposive) sampling strategy. The sample size was 120 infertile. SPSS 26 was used to analyze the data. Results: Fear of intimacy was found significant impact on neuropsychological impairment ( Conclusion: Overall, infertile men in Pakistan had relatively high levels of fear of intimacy, which largely caused neuropsychological impairment. This study can help neuropsychological researchers, mental health professionals, as well as policymakers in improving clinical mental health practices for infertile patients.
Language	English
Publishing date	2023-07-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564218-2
ISSN	1664-0640
ISSN	1664-0640
DOI	10.3389/fpsyt.2023.1049008
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Article ; Online: Paediatric posterior fossa tumour resection rates in a small volume centre: the past decade's experience.

Bhatt, Harsh / Bhatti, Muhammad Imran / Patel, Chirag / Leach, Paul

British journal of neurosurgery

2020 Volume 35, Issue 4, Page(s) 451–455

Abstract: Background: Paediatric brain tumour resection rates have been shown to correlate with outcome and, it is argued, are linked to operator volume and caseload. The British paediatric neurosurgery community has previously debated centralisation of ... ...

Abstract	Background: Paediatric brain tumour resection rates have been shown to correlate with outcome and, it is argued, are linked to operator volume and caseload. The British paediatric neurosurgery community has previously debated centralisation of paediatric neuro-oncology. At the 2018 British Paediatric Neurosurgery Group (BPNG) meeting, a commitment was made to prospectively collect tumour resection data at each Neurosurgical Unit (NSU). Here we review our prospectively-collected 10-year database of the three commonest paediatric posterior fossa tumours - astrocytomas, medulloblastomas and ependymomas. Materials and methods: Our primary outcome was extent of resection (EOR) on post-operative MRI scans reviewed by neuro-radiologists. Secondary outcomes comprised neurosurgical morbidity including infection, need for cerebrospinal fluid (CSF) diversion and the occurrence of posterior fossa syndrome (PFS). Results: 55 children had 62 operations, where our complete resection rates for pilocytic astrocytomas, medulloblastomas and ependymomas were 77%, 79% and 63%, respectively. Both our primary and secondary outcomes were in keeping with the published literature and we discuss here some of the factors which may contribute towards favourable outcomes in a small volume centre. Conclusion: Our results suggest that small volume centres can expect equivalent results to larger volume NSUs with regards to paediatric brain tumour surgery. Continuing efforts nationally for data collection on resection rates and operative outcomes is a key step towards optimising management in these children.
MeSH term(s)	Astrocytoma ; Brain Neoplasms/surgery ; Child ; Ependymoma/surgery ; Humans ; Infratentorial Neoplasms/surgery ; Neurosurgical Procedures
Language	English
Publishing date	2020-12-11
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	639029-8
ISSN	1360-046X ; 0268-8697
ISSN (online)	1360-046X
ISSN	0268-8697
DOI	10.1080/02688697.2020.1859085
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Article ; Online: The incidence of infection for adults undergoing supra-tentorial craniotomy for tumours without hair removal.

Bhatti, M I / Leach, P A

British journal of neurosurgery

2013 Volume 27, Issue 2, Page(s) 218–220

Abstract: Aims & objectives: The aim of the study was to look at the infection rate in adults undergoing craniotomies without hair removal and compare the results with the usual practice of pre-operative shaving/clipping.: Materials & methods: One-hundred ... ...

Abstract	Aims & objectives: The aim of the study was to look at the infection rate in adults undergoing craniotomies without hair removal and compare the results with the usual practice of pre-operative shaving/clipping. Materials & methods: One-hundred consecutive adult patients who had elective supra-tentorial craniotomy for tumour were studied prospectively. A uniform policy of performing surgery without hair removal was adopted. Patients were followed up prospectively to look for surgical site infection. The rate of infection was determined and the results were compared with the published data on similar procedures where hair removal was carried out before surgery. Results: A total of three patients developed surgical-site infection. One infection occurred in the glioma and two in the meningioma subgroup. The rate of infection is comparable to the published figures where pre-operative hair removal was performed routinely. Conclusions: Cranial surgery with hair left in place does not pre-dispose to an increased infection risk for adults undergoing tumour surgery.
MeSH term(s)	Adolescent ; Adult ; Aged ; Brain Neoplasms/surgery ; Craniotomy/methods ; Female ; Hair Removal ; Humans ; Male ; Middle Aged ; Prospective Studies ; Surgical Wound Infection/etiology ; Young Adult
Language	English
Publishing date	2013-04
Publishing country	England
Document type	Comparative Study ; Journal Article
ZDB-ID	639029-8
ISSN	1360-046X ; 0268-8697
ISSN (online)	1360-046X
ISSN	0268-8697
DOI	10.3109/02688697.2012.743968
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Article ; Online: Milligan-Morgan (Open) Versus Ferguson Haemorrhoidectomy (Closed): A Systematic Review and Meta-Analysis of Published Randomized, Controlled Trials.

Bhatti, Muhammad I / Sajid, Muhammad Shafique / Baig, Mirza K

World journal of surgery

2016 Volume 40, Issue 6, Page(s) 1509–1519

Abstract: Objective: The purpose of this article is to systematically analyse the randomized, controlled trials (RCTs) comparing Ferguson or closed haemorrhoidectomy (CH) versus open haemorrhoidectomy (OH) or Milligan-Morgan haemorrhoidectomy in the management of ...

Abstract	Objective: The purpose of this article is to systematically analyse the randomized, controlled trials (RCTs) comparing Ferguson or closed haemorrhoidectomy (CH) versus open haemorrhoidectomy (OH) or Milligan-Morgan haemorrhoidectomy in the management of haemorrhoidal disease (HD). Methods: RCTs on the effectiveness of CH and OH in the management of HD were analysed systematically using RevMan(®), and combined outcome was expressed as odds ratio (OR) and standardized mean difference. Results: Eleven CRTs encompassing 1326 patients were analysed systematically. There was significant heterogeneity among included trials. Therefore, in the random effects model, CH was associated with a reduced post-operative pain (SMD, -0.36; 95 % CI, -0.64, -0.07; z = 2.45; p = 0.01), faster wound healing (OR, 0.08; 95 % CI, 0.02, 0.24; z = 4.33; p < 0.0001), lesser risk of post-operative bleeding (OR, 0.50; 95 % CI, 0.27, 0.91; z = 2.27; p < 0.02) and prolonged duration of operation (SMD, 6.10; 95 % CI, 3.21, 8.98; z = 4.13; p < 0.0001). But the variables such as pain on defecation (SMD, -0.33; 95 % CI, -0.68, 0.03; z = 1.82; p = 0.07), length of hospital stay, post-operative complications, HD recurrence and risk of surgical site infection were similar in both groups. Conclusion: CH has clinically measurable advantages over OH in terms of reduced post-operative pain, lower risk of post-operative bleeding and faster wound healing.
MeSH term(s)	Defecation ; Hemorrhoidectomy/adverse effects ; Hemorrhoidectomy/methods ; Hemorrhoids/surgery ; Humans ; Length of Stay ; Operative Time ; Pain, Postoperative/etiology ; Postoperative Hemorrhage/etiology ; Randomized Controlled Trials as Topic ; Recurrence ; Surgical Wound Infection/etiology ; Treatment Outcome ; Wound Healing
Language	English
Publishing date	2016-06
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Meta-Analysis ; Review
ZDB-ID	224043-9
ISSN	1432-2323 ; 0364-2313
ISSN (online)	1432-2323
ISSN	0364-2313
DOI	10.1007/s00268-016-3419-z
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