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  1. Article ; Online: Gut microbes as biomarkers of ICI response - sharpening the focus.

    Bhutiani, Neal / Wargo, Jennifer A

    Nature reviews. Clinical oncology

    2022  Volume 19, Issue 8, Page(s) 495–496

    MeSH term(s) Biomarkers ; Gastrointestinal Microbiome ; Humans
    Chemical Substances Biomarkers
    Language English
    Publishing date 2022-04-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2491410-1
    ISSN 1759-4782 ; 1759-4774
    ISSN (online) 1759-4782
    ISSN 1759-4774
    DOI 10.1038/s41571-022-00634-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The effect of COVID-19 on orthodontic treatment demand and its delivery in India.

    Grewal, Harpreet / Bhutiani, Neha / Balachandran, Rajiv

    Indian journal of dental research : official publication of Indian Society for Dental Research

    2023  Volume 33, Issue 4, Page(s) 367–372

    Abstract: Introduction: The ongoing pandemic has transformed the entire structural and functional framework of the world including the medical and dental healthcare services. The current study intends to examine the pattern of dynamically changing working ... ...

    Abstract Introduction: The ongoing pandemic has transformed the entire structural and functional framework of the world including the medical and dental healthcare services. The current study intends to examine the pattern of dynamically changing working conditions and orthodontic treatment delivery during the various phases of pandemic.
    Method: An online survey was conducted using Google form for orthodontic specialists practicing in India. Information regarding the impact of the pandemic on various aspects like patient turnover, treatment demand, clinical management, and new challenges faced were analysed through a self-designed close-ended questionnaire for two phases. Phase I (March 2020 to September 2020) corresponded to the onset of COVID 19 pandemic and lockdown, whereas the Phase II (October 2020 to March 2021) coincided with the time of Unlock and resumption of activities thereafter.
    Results: The parameters showing similar trend in Phases I and II included the willingness of ongoing orthodontic patients to report for appointments, choice of treatment modality, number and type of emergencies, cost of materials, guidelines for work, and duration of non-delivery of orthodontic procedures. The new patients reporting, complex orthodontic therapy, tele-consultation, and financial wellbeing showed an improvement while the usage of personal protective equipment kit, fear amongst orthodontists reduced in Phase II.
    Conclusions: Challenging situations warrant prudent measures to combat and continue the essential services, especially those related to the healthcare. A detailed analysis of the various phases of the ongoing pandemic will enable us to devise suitable measures to ensure uninterrupted orthodontic treatment even in such critical times.
    MeSH term(s) Humans ; COVID-19/epidemiology ; SARS-CoV-2 ; Communicable Disease Control ; Orthodontics ; India/epidemiology
    Language English
    Publishing date 2023-04-01
    Publishing country India
    Document type Journal Article
    ZDB-ID 1354886-4
    ISSN 1998-3603 ; 0970-9290
    ISSN (online) 1998-3603
    ISSN 0970-9290
    DOI 10.4103/ijdr.ijdr_136_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Regarding comparative cone-beam computed tomographic evaluation of maxillary incisor intrusion and associated root resorption.

    Sehrawat, Sonam / Grewal, Harpreet / Bhutiani, Neha

    American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics

    2023  Volume 163, Issue 6, Page(s) 739

    MeSH term(s) Humans ; Root Resorption/diagnostic imaging ; Incisor/diagnostic imaging ; Cone-Beam Computed Tomography/methods ; Maxilla/diagnostic imaging
    Language English
    Publishing date 2023-05-26
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 356699-7
    ISSN 1097-6752 ; 0889-5406 ; 0002-9416
    ISSN (online) 1097-6752
    ISSN 0889-5406 ; 0002-9416
    DOI 10.1016/j.ajodo.2023.03.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: ASO Author Reflections: The Broad Impact of the Margin Consensus Guidelines for Breast-Conserving Surgery in DCIS.

    Bhutiani, Neal / Ajkay, Nicolas

    Annals of surgical oncology

    2021  Volume 28, Issue 12, Page(s) 7439–7440

    MeSH term(s) Breast Neoplasms/surgery ; Carcinoma, Ductal, Breast/surgery ; Carcinoma, Intraductal, Noninfiltrating/surgery ; Female ; Humans ; Margins of Excision ; Mastectomy, Segmental
    Language English
    Publishing date 2021-05-26
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-021-10170-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A practical framework for the targeted use of total neoadjuvant therapy for rectal cancer.

    Bhutiani, Neal / Peacock, Oliver / Chang, George J

    Cancer

    2022  Volume 128, Issue 11, Page(s) 2064–2072

    Abstract: Total neoadjuvant therapy (TNT) for rectal cancer is the preoperative delivery of radiation or chemoradiotherapy as well as systemic chemotherapy for the purpose of improving treatment completion rates and decreasing toxicity, maximizing the primary ... ...

    Abstract Total neoadjuvant therapy (TNT) for rectal cancer is the preoperative delivery of radiation or chemoradiotherapy as well as systemic chemotherapy for the purpose of improving treatment completion rates and decreasing toxicity, maximizing the primary tumor response, and improving survival for patients with rectal cancer. This review summarizes the data surrounding TNT, including several recent randomized controlled trials. Moreover, it reviews the literature regarding high-quality surgery and the role of radiation and chemotherapy in the treatment of rectal cancer in the modern era. Finally, it presents an evidence-based protocol for the selective use of TNT in the treatment of patients with rectal cancer.
    MeSH term(s) Antineoplastic Combined Chemotherapy Protocols ; Chemoradiotherapy/methods ; Humans ; Neoadjuvant Therapy/methods ; Neoplasm Staging ; Rectal Neoplasms/pathology
    Language English
    Publishing date 2022-04-04
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 1429-1
    ISSN 1097-0142 ; 0008-543X ; 1934-662X
    ISSN (online) 1097-0142
    ISSN 0008-543X ; 1934-662X
    DOI 10.1002/cncr.34149
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Psychosocial Maternal Perception of the Outcome of Pre Surgical Infant Orthopedics in Infants Born with Cleft Lip and Palate.

    Bhutiani, Neha / Tripathi, Tulika / Rai, Priyank

    The Journal of clinical pediatric dentistry

    2022  Volume 46, Issue 4, Page(s) 299–306

    Abstract: Background: The setback of having a child with cleft lip and palate deeply affects the parents psychology. The Pre Surgical Infant Orthopaedics(PSIO) is a promising procedure for improvement in facial morphology prior to primary lip repair.: Objective! ...

    Abstract Background: The setback of having a child with cleft lip and palate deeply affects the parents psychology. The Pre Surgical Infant Orthopaedics(PSIO) is a promising procedure for improvement in facial morphology prior to primary lip repair.
    Objective: The current study examines the perception of effects of PSIO procedures on the facial appearance of newborns with cleft lip/palate by their mothers and finds its correlation if any, with the change in psychosocial status of the mothers.
    Study design: The mothers of 50 infants(0-6 months) born with cleft lip/palate rated the nasal morphology, extent of cleft defect and overall facial morphology on a Likert's scale before and after PSIO procedure. This was correlated with changes in mother's depression, anxiety and stress levels by using the validated Hindi-version of Depression Anxiety and Stress scale(DASS-42) index before and after PSIO.
    Results: The mothers reported a significant improvement in all the morphological parameters for their infants with PSIO which correlated well with significant reduction in the DASS scores from 22.54(severe) to 7.10(normal) for depression, 20.64(extremely severe) to 6.46(normal) for anxiety and 24.7(severe) to 8.4(normal) for stress.
    Conclusions: The changes in facial morphology by PSIO procedures are well perceived by mothers and significantly improves their depression, anxiety and stress levels.
    MeSH term(s) Cleft Lip/surgery ; Cleft Palate/surgery ; Female ; Humans ; Infant ; Infant, Newborn ; Orthopedics ; Perception
    Language English
    Publishing date 2022-09-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1062408-9
    ISSN 1053-4628 ; 0145-5508
    ISSN 1053-4628 ; 0145-5508
    DOI 10.22514/1053-4625-46.4.7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Comprehensive management of Crouzon syndrome: A case report with three-year follow-up.

    Tripathi, Tulika / Srivastava, Dhirendra / Bhutiani, Neha / Rai, Priyank

    Journal of orthodontics

    2021  Volume 49, Issue 1, Page(s) 71–78

    Abstract: Crouzon syndrome is one of the most common craniosynostosis facial syndromes caused by a mutation in the fibroblast growth factor receptor 2 (FGFR2) gene. Less commonly, there is a mutation of the FGFR3 gene which results in Crouzon syndrome syndrome ... ...

    Abstract Crouzon syndrome is one of the most common craniosynostosis facial syndromes caused by a mutation in the fibroblast growth factor receptor 2 (FGFR2) gene. Less commonly, there is a mutation of the FGFR3 gene which results in Crouzon syndrome syndrome with acanthosis nigricans. It involves the premature fusion of sutures of the cranial vault, base, orbital and maxillary region. The clinical presentation of this congenital deformity depends on the pattern and timing of sutural fusion. The present report describes the features and management of this syndrome in an 18-year-old woman. The patient presented with a hypoplastic maxilla, deficient midface, exorbitism due to shallow orbits, severe crowding and bilateral crossbite. A multidisciplinary approach involving orthodontics and surgical intervention with distraction osteogenesis brought about marked improvement in the facial profile, occlusion and upper airway. The aesthetics and function were greatly enhanced, and the results were found to be stable at the end of three years.
    MeSH term(s) Adolescent ; Craniofacial Dysostosis/complications ; Craniofacial Dysostosis/diagnostic imaging ; Craniofacial Dysostosis/surgery ; Craniosynostoses/genetics ; Esthetics, Dental ; Female ; Follow-Up Studies ; Humans ; Skull
    Language English
    Publishing date 2021-06-08
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2011954-9
    ISSN 1465-3133 ; 0301-228X ; 1465-3125
    ISSN (online) 1465-3133
    ISSN 0301-228X ; 1465-3125
    DOI 10.1177/14653125211019412
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Evaluating the early impact of Medicaid expansion on trends in diagnosis and treatment of benign gallbladder disease in Kentucky.

    Bhutiani, N / Harbrecht, B G / Scoggins, C R / Bozeman, M C

    American journal of surgery

    2019  Volume 218, Issue 3, Page(s) 584–589

    Abstract: Background: In January 2014, Kentucky expanded Medicaid coverage in an effort to improve access to healthcare. This study evaluated the early impact of Medicaid expansion on diagnosis and treatment of benign gallbladder disease in Kentucky.: Methods: ...

    Abstract Background: In January 2014, Kentucky expanded Medicaid coverage in an effort to improve access to healthcare. This study evaluated the early impact of Medicaid expansion on diagnosis and treatment of benign gallbladder disease in Kentucky.
    Methods: Administrative claims data were queried for patients undergoing cholecystectomy for benign gallbladder disease between 2011 and 2015. Demographic, procedure, and outcome variables from 2011 to 2013 (PRE) and 2014-2015 (POST) were compared.
    Results: After Medicaid expansion, patients were more likely to have their operation performed as an outpatient (80.0% vs. 78.2%, p < 0.001). A significant trend was noted toward a shorter hospital stay (p < 0.001) among inpatients. For both inpatients and outpatients, a significant shift was noted toward increased hospital charges (p < 0.001).
    Conclusions: The expansion of Kentucky Medicaid in 2014 has been associated with an increase in outpatient cholecystectomy, shorter hospital stays for inpatients, and increased hospital charges for both inpatients and outpatients. Increased charges for all procedures may represent a mechanism for hospitals to offset the cost of providing global care for more patients.
    MeSH term(s) Adolescent ; Adult ; Cholecystectomy ; Delivery of Health Care/trends ; Gallbladder Diseases/diagnosis ; Gallbladder Diseases/surgery ; Humans ; Kentucky ; Medicaid/organization & administration ; Middle Aged ; Retrospective Studies ; Time Factors ; United States ; Young Adult
    Language English
    Publishing date 2019-01-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2953-1
    ISSN 1879-1883 ; 0002-9610
    ISSN (online) 1879-1883
    ISSN 0002-9610
    DOI 10.1016/j.amjsurg.2019.01.013
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  9. Article ; Online: Is More Anesthesia Care Better in Endoscopy? Comparing the Safety and Cost of Conscious Sedation and Anesthesia Provider-Based Care.

    Bhutiani, N / Bruenderman, E / Davidyuk, V / Mortensen, G F / O'Brien, S / Martin, R C G / Vitale, Gary C

    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

    2021  Volume 26, Issue 2, Page(s) 483–485

    MeSH term(s) Anesthesia/adverse effects ; Anesthesia/economics ; Conscious Sedation/adverse effects ; Conscious Sedation/economics ; Endoscopy, Gastrointestinal/adverse effects ; Endoscopy, Gastrointestinal/economics ; Humans ; Patient Care/adverse effects ; Patient Care/economics
    Language English
    Publishing date 2021-09-10
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 2012365-6
    ISSN 1873-4626 ; 1934-3213 ; 1091-255X
    ISSN (online) 1873-4626 ; 1934-3213
    ISSN 1091-255X
    DOI 10.1007/s11605-021-05120-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Closure of large alveolar defect by maxillary alveolar distraction using a vector-controlled distractor appliance in cleft patients: A pilot study.

    Singh, Navneet / Tripathi, Tulika / Mohanty, Sujata / Rai, Priyank / Bhutiani, Neha

    Journal of oral biology and craniofacial research

    2021  Volume 11, Issue 2, Page(s) 277–283

    Abstract: Objective: To assess the treatment outcome of custom made maxillary transport distractor appliance for closure of large alveolar clefts.: Method: A pilot study was conducted on 12 large alveolar cleft defects present in 11 non-syndromic cleft lip and ...

    Abstract Objective: To assess the treatment outcome of custom made maxillary transport distractor appliance for closure of large alveolar clefts.
    Method: A pilot study was conducted on 12 large alveolar cleft defects present in 11 non-syndromic cleft lip and palate patients (1 bilateral and 10 unilateral) in the age group of 16-25 years. All the subjects underwent pre-surgical orthodontics followed by alveolar distraction using custom-made distractor appliance. Study models, lateral cephalogram, panoramic radiograph and cone beam computed tomograms were obtained pre-surgically (T0) and after distractor removal (T1). The reduction in the width and volume of the alveolar cleft defect and change in the mesiodistal axial inclination of the teeth in transport segment following distraction were recorded. P value ​< ​0.05 was considered statistically significant.
    Results: Significant reduction in cleft width (9.18 ​mm), volume (89.82 ​mm
    Conclusion: The custom-made tooth borne distraction appliance successfully closed the large alveolar cleft defect with minimal or no inadvertent effects on the oral tissues.
    Language English
    Publishing date 2021-02-19
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2212-4268
    ISSN 2212-4268
    DOI 10.1016/j.jobcr.2021.02.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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