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  1. Book ; Online: Cancer Biomarkers in Body Fluids

    Bianchi, Fabrizio

    2023  

    Keywords Research & information: general ; Physics ; primary breast cancer ; circulating nucleosomes ; circulating tumor cells ; plasminogen activator inhibitor-1 ; cytokines ; prostate cancer ; breast cancer ; treatment decisions ; exosomes ; molecular composition ; cancer pathogenesis ; diagnostics ; therapeutics ; leptomeningeal metastasis ; cerebrospinal fluid ; extracellular vesicle ; biomarker ; RNA sequencing ; small non-coding RNA ; microRNA ; exo-oncomiRNAS ; TWEAK ; semen ; rheumatoid factor ; autoimmunity ; autoantibodies ; cancer ; predictive biomarker ; prognostic biomarker ; cancer progression ; cancer development ; immunotherapy ; cancer susceptibility ; tumor recurrence ; tumor load ; fecal immunochemical test (FIT) ; colonoscopy ; flexible sigmoidoscopy ; liquid biopsy ; mRNA ; ctDNA ; proteins ; extracellular vesicles ; biomarkers ; exosome ; lung cancer ; miRNA ; plasma ; serum ; volatile organic compounds (VOCs) ; gas chromatography (GC) ; mass spectrometry (MS) ; headspace solid phase microextraction (HS-SPME) ; breast cancer biomarkers ; principal component analysis (PCA) ; linear discriminant analysis (LDA) ; principal component regression (PCR) ; cfDNA ; hereditary and familial pancreatic cancer ; somatic mutation profiling ; potentially druggable genes ; uveal melanoma ; circulating tumor DNA ; next generation sequencing ; PKC inhibitor ; treatment ; response ; melanoma ; ovarian cancer ; lipidomics ; lipid ; prognosis ; ceramide ; phospholipid ; plasmalogen ; patient stratification ; outcome ; personalized medicine ; neuroblastoma ; immune monitoring ; anti-GD2 ; IL-2 ; GM-CSF ; ASCT ; dinutuximab ; anti-PD-1 ; urothelial cancer ; blood biomarkers ; NETs ; disease modelling ; machine learning ; metabolic signaling ; molecular pathways ; plasma metabolites ; diagnostic biomarkers ; urine ; urine liquid biopsy ; DNA ; sncRNA ; bladder cancer ; metabolic pathways ; metabolism ; metabolomics ; epigenetics ; miRNAs ; epigenetic biomarkers ; DNA methylation ; micro-RNAs ; human papillomavirus ; oropharyngeal squamous cell carcinoma ; treatment de-escalation ; E7 oncoprotein ; HPV DNA ; HPV antibodies ; ELISA ; cancer biomarkers ; diagnosis ; early detection ; n/a ; early diagnosis
    Language English
    Size 1 electronic resource (490 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English
    HBZ-ID HT030722274
    ISBN 9783036566481 ; 3036566481
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Ospedali e politiche assistenziali a Vicenza nel Quattrocento

    Bianchi, Francesco

    (Reti Medievali E-Book)

    2014  

    Series title Reti Medievali E-Book
    Keywords History: earliest times to present day
    Language 0|i
    Size 1 electronic resource (264 pages)
    Publisher Firenze University Press
    Publishing place Florence
    Document type Book ; Online
    Note Italian ; Open Access
    HBZ-ID HT021615258
    ISBN 9788892733787 ; 8892733788
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Cannabinoids for Behavioral Symptoms in Dementia: An Overview.

    Broers, Barbara / Bianchi, Federica

    Pharmacopsychiatry

    2024  

    Abstract: Dementia, with loss of memory, cognitive abilities, and independent daily functioning, is increasing worldwide, related to an aging population. Currently, there is no curative treatment for dementia. Treatment of the frequently occurring behavioral and ... ...

    Abstract Dementia, with loss of memory, cognitive abilities, and independent daily functioning, is increasing worldwide, related to an aging population. Currently, there is no curative treatment for dementia. Treatment of the frequently occurring behavioral and psychological symptoms of dementia (BPSD) is partially effective and associated with significant side effects. Cannabinoids are lipophilic molecules acting on the CB1 end CB2 receptors, essential for main biological processes such as sleep, appetite, memory, and pain. Cannabinoids might have a positive impact on amyloid formation in Alzheimer's disease, the main form of dementia, and on BPSD symptoms. Most knowledge currently concerns delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). In the context of dementia and BPSD, THC might be beneficial for associated spasticity and possible pain or lack of appetite and CBD probably works better on sleep, agitation, and anxiety. This overview of prospective clinical studies and randomized clinical trials, published between 2005 and April 2023, using cannabinoids for BPSD suggests that older studies using low-dose oral synthetic THC showed no positive results. Still, more recent studies using THC/CBD-based oral medication at higher doses show promising results and are feasible and safe in this elderly polymedicated population. Several RCTs are ongoing and planned worldwide, and we hope other trials will follow to establish clinical efficiency and optimal dosing, as well as other outcomes such as deprescribing other medications and facilitation of care. We suggest that researchers also address the more sociological aspects of prescribing cannabinoids for dementia and BPSD in their specific context.
    Language English
    Publishing date 2024-03-06
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 605670-2
    ISSN 1439-0795 ; 0720-4280 ; 0176-3679
    ISSN (online) 1439-0795
    ISSN 0720-4280 ; 0176-3679
    DOI 10.1055/a-2262-7837
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 481: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Diversity, integration, and variability of intergenerational relationships in old age: New insights from personal network research.

    Vacca, Raffaele / Bianchi, Federico

    Social science research

    2024  Volume 119, Page(s) 102991

    Abstract: Relationships between family members from different generations have long been described as a source of solidarity and support in aging populations and, more recently, as a potential risk factor for COVID-19 contagion. Personal or egocentric network ... ...

    Abstract Relationships between family members from different generations have long been described as a source of solidarity and support in aging populations and, more recently, as a potential risk factor for COVID-19 contagion. Personal or egocentric network research offers a powerful kit of conceptual and methodological tools to study these relationships, but this has not yet been employed to its full potential in the literature. We investigate the heterogeneity, social integration, and individual correlates of intergenerational relationships in old age analyzing highly granular data on the personal networks of 230 older adults (2747 social ties) from a local survey in one of the areas of the world at the forefront of global aging trends (northern Italy). Using information on different layers in broad egocentric networks and on the structure of connectivity among the social contacts of aging people, we propose multiple conceptualizations and measures of intergenerational connectedness. Results show that intergenerational relationships are strongly integrated, but also highly diverse and variable, in older adults' social networks. Different types of intergenerational ties exist in different network layers, with various relational roles, degrees of tie strength, and patterns of association with individual and tie characteristics. We discuss how new and existing personal network data can be leveraged to consider novel questions and hypotheses about intergenerational relationships in contemporary aging families.
    MeSH term(s) Humans ; Aged ; Family ; Italy ; Risk Factors ; Social Integration ; Social Networking
    Language English
    Publishing date 2024-02-13
    Publishing country United States
    Document type Journal Article
    ISSN 1096-0317
    ISSN (online) 1096-0317
    DOI 10.1016/j.ssresearch.2024.102991
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Chest wall reconstruction, prosthesis and allografts: a narrative review.

    Girotti, Paolo Nicola Camillo / Bianchi, Fabrizio

    Journal of thoracic disease

    2023  Volume 15, Issue 12, Page(s) 7077–7087

    Abstract: Background and objective: What is the best material in the case of prosthesis used to replace major chest wall resection is still unknown. We reviewed most significant literature focused on the type of prosthetic materials available by highlighting ... ...

    Abstract Background and objective: What is the best material in the case of prosthesis used to replace major chest wall resection is still unknown. We reviewed most significant literature focused on the type of prosthetic materials available by highlighting their relative pros and cons.
    Methods: We reviewed most significant articles, including clinical results of relevant case series (retrospective studies), published in English in the last 23 years: PubMed, Embase and Scopus databases were used in our search in the period between the 1
    Key content and findings: Overall, our literature review revealed lack of uniformity or conformity in the surgical strategies described for chest wall reconstruction with no internationally accepted standard in terms of decisions and optimal prosthetic materials and type of prostheses (soft, rigid, biological). Despite the increased interest in chest wall reconstruction, we observed a general lack of substantial prospective and multicentric studies. Likewise, there are not substantial data which may guide to the choice of optimal prosthetics in terms of characteristics and biocompatibility.
    Conclusions: A variety of materials are available for reconstruction, including synthetic and biological meshes, flexible and rigid patches, and metal osteosynthesis systems. The material chosen should be optimized to each patient and damaged tissues to be restored. Prospective and multicentric studies are necessary to address current limits in this surgical field.
    Language English
    Publishing date 2023-12-26
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd-23-650
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [No title information]

    Broers, Barbara / Bianchi, Federica

    Pharmacopsychiatry

    2024  

    Abstract: Dementia, with loss of memory, cognitive abilities, and independent daily functioning, is increasing worldwide, related to an aging population. Currently, there is no curative treatment for dementia. Treatment of ... ...

    Abstract Dementia, with loss of memory, cognitive abilities, and independent daily functioning, is increasing worldwide, related to an aging population. Currently, there is no curative treatment for dementia. Treatment of the frequently occurring behavioral and psychological symptoms of dementia (BPSD) is partially effective and associated with significant side effects. Cannabinoids are lipophilic molecules acting on the CB1 end CB2 receptors, essential for main biological processes such as sleep, appetite, memory, and pain. Cannabinoids might have a positive impact on amyloid formation in Alzheimer’s disease, the main form of dementia, and on BPSD symptoms. Most knowledge currently concerns delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). In the context of dementia and BPSD, THC might be beneficial for associated spasticity and possible pain or lack of appetite and CBD probably works better on sleep, agitation, and anxiety. This overview of prospective clinical studies and randomized clinical trials, published between 2005 and April 2023, using cannabinoids for BPSD suggests that older studies using low-dose oral synthetic THC showed no positive results. Still, more recent studies using THC/CBD-based oral medication at higher doses show promising results and are feasible and safe in this elderly polymedicated population. Several RCTs are ongoing and planned worldwide, and we hope other trials will follow to establish clinical efficiency and optimal dosing, as well as other outcomes such as deprescribing other medications and facilitation of care. We suggest that researchers also address the more sociological aspects of prescribing cannabinoids for dementia and BPSD in their specific context.
    Keywords dementia ; medical cannabis ; dronabiol ; BPSD ; cannabinoids
    Language English
    Publishing date 2024-03-06
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 605670-2
    ISSN 1439-0795 ; 0176-3679 ; 0720-4280
    ISSN (online) 1439-0795
    ISSN 0176-3679 ; 0720-4280
    DOI 10.1055/a-2262-7837
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 481: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: The epicondilite o tennis-elbow.

    BIANCHI, F

    Studi di medicina e chirurgia dello sport

    2014  Volume 3, Issue 6, Page(s) 262–284

    Title translation L'epicondilite omerale o tennis-elbow.
    MeSH term(s) Elbow ; Elbow Joint ; Humans ; Sports
    Language French
    Publishing date 2014-01-04
    Publishing country Italy
    Document type Journal Article
    ISSN 0371-3687
    ISSN 0371-3687
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: A public health perspective on the responsibility of mass media for the outcome of the anti-COVID-19 vaccination campaign: the AstraZeneca case.

    Bianchi, F P / Tafuri, S

    Annali di igiene : medicina preventiva e di comunita

    2022  Volume 34, Issue 6, Page(s) 650–655

    Abstract: Abstract: On February 9, 2021, the Italian Ministry of Health made the "Covid-19 vaccine AstraZeneca" (now "Vaxzevria") available for use in the anti-COVID-19 vaccination campaign. However, in early March, the media reported that five people died a few ... ...

    Abstract Abstract: On February 9, 2021, the Italian Ministry of Health made the "Covid-19 vaccine AstraZeneca" (now "Vaxzevria") available for use in the anti-COVID-19 vaccination campaign. However, in early March, the media reported that five people died a few days after receiving the vaccine. The reaction among both those already vaccinated and the vaccine candidates was one of near panic. The subsequent events have had long-lasting consequences, as 10-20% of vaccine candidates have since refused vaccination with the AstraZeneca vac-cine, so in addition to the delay in vaccination, ~200,000 doses of it were not administered. The goal of the vaccination campaign in Italy, when operating at full capacity, was to administer 500,000 doses per day, for a total of 3,500,000 doses per week. In this large amount of people, it is statistically certain that a certain number of subjects will develop non-vaccine related health problems or even die from causes unrelated to having been vaccinated. At this time in history, press reports must be inspired by a strong sense of responsibility and awareness of the potential consequences of misinformation; this is particularly true, especially because also the social media get inevitably involved.
    MeSH term(s) Attitude to Health ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Health Knowledge, Attitudes, Practice ; Humans ; Immunization Programs ; Mass Media ; Public Health ; Vaccination
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-02-03
    Publishing country Italy
    Document type Observational Study
    ZDB-ID 1018045-x
    ISSN 1120-9135 ; 0029-6287
    ISSN 1120-9135 ; 0029-6287
    DOI 10.7416/ai.2022.2499
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2845: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: From Ties to Events in the Analysis of Interorganizational Exchange Relations.

    Bianchi, Federica / Lomi, Alessandro

    Organizational research methods

    2022  Volume 26, Issue 3, Page(s) 524–565

    Abstract: Relational event models expand the analytical possibilities of existing statistical models for interorganizational networks by: (i) making efficient use of information contained in the sequential ordering of observed events connecting sending and ... ...

    Abstract Relational event models expand the analytical possibilities of existing statistical models for interorganizational networks by: (i) making efficient use of information contained in the sequential ordering of observed events connecting sending and receiving units; (ii) accounting for the intensity of the relation between exchange partners, and (iii) distinguishing between short- and long-term network effects. We introduce a recently developed relational event model (REM) for the analysis of continuously observed interorganizational exchange relations. The combination of efficient sampling algorithms and sender-based stratification makes the models that we present particularly useful for the analysis of very large samples of relational event data generated by interaction among heterogeneous actors. We demonstrate the empirical value of event-oriented network models in two different settings for interorganizational exchange relations-that is, high-frequency overnight transactions among European banks and patient-sharing relations within a community of Italian hospitals. We focus on patterns of direct and generalized reciprocity while accounting for more complex forms of dependence present in the data. Empirical results suggest that distinguishing between degree- and intensity-based network effects, and between short- and long-term effects is crucial to our understanding of the dynamics of interorganizational dependence and exchange relations. We discuss the general implications of these results for the analysis of social interaction data routinely collected in organizational research to examine the evolutionary dynamics of social networks within and between organizations.
    Language English
    Publishing date 2022-03-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2029600-9
    ISSN 1552-7425 ; 1094-4281
    ISSN (online) 1552-7425
    ISSN 1094-4281
    DOI 10.1177/10944281211058469
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Biologics and anti-Sars Cov2 vaccination in severe asthma riding the big wave: Unity is strength!

    Guarnieri, G / Molena, B / Chieco Bianchi, F / Vianello, A

    Pulmonology

    2022  Volume 29, Issue 4, Page(s) 273–275

    MeSH term(s) Humans ; Biological Products ; COVID-19/prevention & control ; Asthma
    Chemical Substances Biological Products
    Language English
    Publishing date 2022-06-09
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 3009651-0
    ISSN 2531-0437 ; 2531-0429
    ISSN (online) 2531-0437
    ISSN 2531-0429
    DOI 10.1016/j.pulmoe.2022.06.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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