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  1. Article ; Online: The influence of depression on clinical outcomes of total shoulder arthroplasty: a systematic Review.

    Bindi, Victoria E / Hones, Keegan M / Schoch, Bradley S / Hampton, Hailey L / Wright, Thomas W / King, Joseph J / Hao, Kevin A

    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

    2024  

    Abstract: Purpose: Much of the current literature on total shoulder arthroplasty (TSA) has assessed the impact of preoperative medical comorbidities on postoperative clinical outcomes. The literature concerning the impact of psychological disorders such as ... ...

    Abstract Purpose: Much of the current literature on total shoulder arthroplasty (TSA) has assessed the impact of preoperative medical comorbidities on postoperative clinical outcomes. The literature concerning the impact of psychological disorders such as depression on TSA has increased in popularity in recent years, but there lacks a thorough review of the influence of depression on postoperative pain and functional outcomes.
    Methods: We queried PubMed/MEDLINE and identified six clinical studies that evaluated the influence of a psychiatric diagnosis of depression on patient outcomes after TSA. Studies that discussed the impacts of depression on TSA, including PROs or adverse events in adults, were included. Studies focused on other psychologic pathology, non-TSA shoulder treatments, or TSA not for primary osteoarthritis were excluded. Non-clinical studies, systematic reviews, letters to the editor, commentaries, dissertations, books, and book chapters were excluded.
    Results: Three cohort studies described patient-reported pain and functional outcomes and three database studies assessed the risk of postoperative complications. Cohort studies demonstrated that the prevalence of depression in patients undergoing TSA decreased from preoperatively to 12-months postoperatively. Two studies demonstrated that depression is an independent predictor of less pre- to postoperative improvement in the ASES score at minimum 2-year follow-up; however, one study found the difference between patients with and without depression did not exceed the minimum clinically important difference. Database studies demonstrated that depression was associated with higher rates of blood transfusion (n = 1, OR = 1.8), anemia (n = 1, OR = 1.65), wound infection (n = 2, OR = 1.41-2.09), prosthetic revision (n = 1, OR = 1.92), and length of hospital stay (n = 3, LOS = 2.5-3 days).
    Conclusion: Although patients with a preoperative diagnosis of depression undergoing TSA can achieve satisfactory relief of shoulder pain and restoration of function, they may experience poorer patient-reported outcomes and a higher risk of postoperative adverse events compared to their peers. Surgeons should be cognizant of the influence of depression in their patients to facilitate proper patient selection that maximizes patient satisfaction, function, and minimizes the risk of adverse events following TSA.
    Level of evidence: Level IV.
    Language English
    Publishing date 2024-03-25
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 1231084-0
    ISSN 1432-1068 ; 1633-8065 ; 0948-4817 ; 0940-3264
    ISSN (online) 1432-1068
    ISSN 1633-8065 ; 0948-4817 ; 0940-3264
    DOI 10.1007/s00590-024-03911-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Comparison of Pain Scores and Functional Outcomes of Patients Undergoing Arthroscopic Hip Labral Repair and Concomitant Capsular Repair or Plication Versus No Closure.

    Bindi, Victoria E / Hao, Kevin A / Freeman, David A / Olowofela, Bankole O / Moser, Michael W / Farmer, Kevin W / Pazik, Marissa / Roach, Ryan P

    Orthopaedic journal of sports medicine

    2024  Volume 12, Issue 4, Page(s) 23259671241243303

    Abstract: Background: The need for capsular closure during arthroscopic hip labral repair is debated.: Purpose: To compare pain and functional outcomes in patients undergoing arthroscopic hip labral repair with concomitant repair or plication of the capsule ... ...

    Abstract Background: The need for capsular closure during arthroscopic hip labral repair is debated.
    Purpose: To compare pain and functional outcomes in patients undergoing arthroscopic hip labral repair with concomitant repair or plication of the capsule versus no closure.
    Study design: Cohort study.
    Methods: Outcomes were compared between patients undergoing arthroscopic hip labral repair with concomitant repair or plication of the capsule versus no closure at up to 2 years postoperatively and with stratification by age and sex. Patients with lateral center-edge angle <20°, a history of instability, a history of prior arthroscopic surgery in the ipsilateral hip, or a history of labral debridement only were excluded. Subanalysis was performed between patients undergoing no capsular closure who were propensity score matched 1:1 with patients undergoing repair or plication based on age, sex, and preoperative Modified Harris Hip Score (MHHS). We compared patients who underwent T-capsulotomy with concomitant capsular closure matched 1:5 with patients who underwent an interportal capsulotomy with concomitant capsular repair based on age, sex, and preoperative MHHS.
    Results: Patients undergoing capsular closure (n = 1069), compared with the no-closure group (n = 230), were more often female (68.6% vs 53.0%, respectively;
    Conclusion: When sex, age, and preoperative MHHS were controlled, capsular closure and no capsular closure after arthroscopic hip labral repair were associated with similar pain and functional outcomes for patients up to 2 years postoperatively.
    Language English
    Publishing date 2024-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2706251-X
    ISSN 2325-9671
    ISSN 2325-9671
    DOI 10.1177/23259671241243303
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Oxygen therapy attenuates neuroinflammation after spinal cord injury.

    Sunshine, Michael D / Bindi, Victoria E / Nguyen, Branden L / Doerr, Vivian / Boeno, Franccesco P / Chandran, Vijayendran / Smuder, Ashley J / Fuller, David D

    Journal of neuroinflammation

    2023  Volume 20, Issue 1, Page(s) 303

    Abstract: Acute hyperbaric ... ...

    Abstract Acute hyperbaric O
    MeSH term(s) Rats ; Male ; Female ; Animals ; Hyperbaric Oxygenation ; Neuroinflammatory Diseases ; Spinal Cord Injuries/complications ; Spinal Cord Injuries/therapy ; Spinal Cord Injuries/metabolism ; Spinal Cord/pathology ; Inflammation/metabolism ; Oxygen/metabolism
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2023-12-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2156455-3
    ISSN 1742-2094 ; 1742-2094
    ISSN (online) 1742-2094
    ISSN 1742-2094
    DOI 10.1186/s12974-023-02985-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Effects of Hyperbaric Oxygen Preconditioning on Doxorubicin Cardiorespiratory Toxicity.

    Doerr, Vivian / Montalvo, Ryan N / Nguyen, Branden L / Boeno, Franccesco P / Sunshine, Michael D / Bindi, Victoria E / Fuller, David D / Smuder, Ashley J

    Antioxidants (Basel, Switzerland)

    2022  Volume 11, Issue 10

    Abstract: Cardiorespiratory dysfunction resulting from doxorubicin (DOX) chemotherapy treatment is a debilitating condition affecting cancer patient outcomes and quality of life. DOX treatment promotes cardiac and respiratory muscle pathology due to enhanced ... ...

    Abstract Cardiorespiratory dysfunction resulting from doxorubicin (DOX) chemotherapy treatment is a debilitating condition affecting cancer patient outcomes and quality of life. DOX treatment promotes cardiac and respiratory muscle pathology due to enhanced reactive oxygen species (ROS) production, mitochondrial dysfunction and impaired muscle contractility. In contrast, hyperbaric oxygen (HBO) therapy is considered a controlled oxidative stress that can evoke a substantial and sustained increase in muscle antioxidant expression. This HBO-induced increase in antioxidant capacity has the potential to improve cardiac and respiratory (i.e., diaphragm) muscle redox balance, preserving mitochondrial function and preventing muscle dysfunction. Therefore, we determined whether HBO therapy prior to DOX treatment is sufficient to enhance muscle antioxidant expression and preserve muscle redox balance and cardiorespiratory muscle function. To test this, adult female Sprague Dawley rats received HBO therapy (2 or 3 atmospheres absolute (ATA), 100% O
    Language English
    Publishing date 2022-10-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox11102073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Mitigating Fracture of the Acromion and Scapular Spine After Reverse Shoulder Arthroplasty: A Critical Analysis Review of Patient and Surgical Risk Factors.

    Buchanan, Timothy R / Bindi, Victoria E / Caban-Klepac, Ettienne / Hones, Keegan M / Wright, Thomas W / Schoch, Bradley S / King, Joseph J / Hao, Kevin A

    JBJS reviews

    2023  Volume 11, Issue 12

    Abstract: Level of evidence: Level V. Narrative Review. See Instructions for Authors for a complete description of levels of evidence. ...

    Abstract Level of evidence: Level V. Narrative Review. See Instructions for Authors for a complete description of levels of evidence.
    MeSH term(s) Humans ; Acromion/injuries ; Arthroplasty, Replacement, Shoulder/adverse effects ; Fractures, Bone/prevention & control ; Risk Factors
    Language English
    Publishing date 2023-12-11
    Publishing country United States
    Document type Review ; Journal Article
    ISSN 2329-9185
    ISSN (online) 2329-9185
    DOI e23.00175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Anatomic versus reverse total shoulder arthroplasty outcomes after prior contralateral anatomic total shoulder arthroplasty in patients with bilateral primary osteoarthritis with an intact rotator cuff.

    Turnbull, Lacie M / Hao, Kevin A / Bindi, Victoria E / Wright, Jonathan O / Wright, Thomas W / Farmer, Kevin W / Vasilopoulos, Terrie / Struk, Aimee M / Schoch, Bradley S / King, Joseph J

    International orthopaedics

    2023  Volume 48, Issue 3, Page(s) 801–807

    Abstract: Purpose: We aimed to compare outcomes in patients that underwent bilateral anatomic total shoulder arthroplasty (aTSA) vs. aTSA/ reverse total shoulder arthroplasty (rTSA) for rotator cuff-intact glenohumeral osteoarthritis (RCI-GHOA) to further ... ...

    Abstract Purpose: We aimed to compare outcomes in patients that underwent bilateral anatomic total shoulder arthroplasty (aTSA) vs. aTSA/ reverse total shoulder arthroplasty (rTSA) for rotator cuff-intact glenohumeral osteoarthritis (RCI-GHOA) to further elucidate the role of rTSA in this patient population.
    Methods: A single-institution prospectively collected shoulder arthroplasty database was reviewed for patients undergoing bilateral total shoulder arthroplasty (TSA) for RCI-GHOA with a primary aTSA and subsequent contralateral aTSA or rTSA. Outcome scores (SPADI, SST, ASES, UCLA, Constant) and active range of motion (abduction, forward elevation [FE], external and internal rotation [ER and IR]) were evaluated. Clinically relevant benchmarks (minimal clinically important difference [MCID], substantial clinical benefit [SCB], and patient acceptable symptomatic state [PASS]) were evaluated against values in prior literature. Incidence of surgical complications and revision rates were examined in qualifying patients as well as those without <two year follow-up.<br />Results: Of the 55 bilateral TSA patients with an intact rotator cuff, 46 underwent aTSA/aTSA and 9 underwent aTSA/rTSA. At the time of the second TSA, patients undergoing aTSA/rTSA were older (71 ± 4 vs. 67 ± 7, P = .032) and more commonly had inflammatory arthritis (44% vs. 11%, P = .031). Mean time to the second TSA was shorter for aTSA/aTSA (2.3 ± 2.8 vs. 4.4 ± 3.6 years, P < .001). Postoperative outcomes were similar after the first aTSAs between groups with similar proportions achieving the MCID, SCB, and PASS (all P > .05). The 2nd TSAs between groups were similar preoperatively, but aTSA/rTSA had superior outcome scores, overhead motion, and active abduction compared to patients that underwent aTSA/aTSA. There were no differences in active ER and IR scores or complication rates between groups.
    Conclusion: Patients with RCI-GHOA have excellent clinical outcomes after either aTSA/aTSA or aTSA/rTSA.
    MeSH term(s) Humans ; Arthroplasty, Replacement, Shoulder/adverse effects ; Rotator Cuff/surgery ; Shoulder Joint/surgery ; Treatment Outcome ; Retrospective Studies ; Osteoarthritis/surgery ; Osteoarthritis/etiology ; Range of Motion, Articular
    Language English
    Publishing date 2023-11-30
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 80384-4
    ISSN 1432-5195 ; 0341-2695
    ISSN (online) 1432-5195
    ISSN 0341-2695
    DOI 10.1007/s00264-023-06044-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Early outcomes after first reverse total shoulder arthroplasty better prognosticate contralateral success compared with early outcomes after anatomic total shoulder arthroplasty.

    Hao, Kevin A / Bindi, Victoria E / Turnbull, Lacie M / Wright, Jonathan O / Wright, Thomas W / Farmer, Kevin W / Vasilopoulos, Terrie / Struk, Aimee M / Schoch, Bradley S / King, Joseph J

    Journal of shoulder and elbow surgery

    2023  

    Abstract: Background: The ideal timing between bilateral total shoulder arthroplasty (TSA) is unclear. The purpose of this study is to determine whether early outcomes after first TSA can be used to predict clinical outcomes after TSA of the contralateral ... ...

    Abstract Background: The ideal timing between bilateral total shoulder arthroplasty (TSA) is unclear. The purpose of this study is to determine whether early outcomes after first TSA can be used to predict clinical outcomes after TSA of the contralateral shoulder and to evaluate the ideal time after TSA to perform the contralateral shoulder.
    Methods: A single-institution prospectively collected shoulder arthroplasty database was reviewed. Patients who underwent bilateral primary anatomic or reverse TSA (aTSA + rTSA) without an indication of fracture, tumor, or infection were identified. Included patients had minimum 2-year follow-up on their second TSA and postoperative follow-up after their first TSA at 3 months, 6 months, 1 year, or 2 years. Our primary outcome was whether outcome scores and motion at 3-month, 6-month, 1-year, and 2-year follow-up after first TSA predicted clinical success after second TSA at final follow-up, defined as achieving the patient acceptable symptomatic state (PASS = the highest level of symptoms beyond which patients consider themselves well). Outcomes included the American Shoulder and Elbow Surgeons and Constant scores, abduction, forward elevation, and external/internal-rotation. Multivariable logistic regression determined whether postoperative outcomes after first TSA were predictive of achieving the PASS after second TSA independent of age, sex, and body mass index. Receiver operating characteristic analysis determined cutoffs of postoperative outcomes after first TSA at each time point that best predicted achieving the prosthesis-specific PASS after second TSA.
    Results: One hundred thirty-four patients were included in the final analysis (110 aTSA and 158 rTSA). Range of motion and outcome scores at late (1- or 2-year) follow-up after first aTSA were more predictive of achieving the second TSA PASS compared with early (3- or 6-month) outcomes. In contrast, outcomes after early and late follow-up after first rTSA were similarly predictive of achieving the second TSA PASS. Specifically, the Constant score threshold at 2 years after first aTSA (79.4; area under the curve [AUC] = 0.804) better differentiated achieving the second TSA PASS vs. the 6-month threshold (72.0; AUC = 0.600). In contrast, the Constant score threshold at 2 years after first rTSA (76.4; AUC = 0.703) was similarly discriminant of achieving the second TSA PASS compared with the 6-month threshold (65.8; AUC = 0.711).
    Conclusions: Patients with good outcomes after first rTSA can be counseled on contralateral TSA as early as 3 months postoperatively with confidence of a similar result on the contralateral side. In contrast, success after first aTSA does not reliably predict contralateral success until ≥1 year.
    Language English
    Publishing date 2023-11-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1170782-3
    ISSN 1532-6500 ; 1058-2746
    ISSN (online) 1532-6500
    ISSN 1058-2746
    DOI 10.1016/j.jse.2023.10.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Case Studies in Neuroscience: Neuropathology and diaphragm dysfunction in ventilatory failure from late-onset Pompe disease.

    Fuller, David D / Trejo-Lopez, Jorge A / Yachnis, Anthony T / Sunshine, Michael D / Rana, Sabhya / Bindi, Victoria E / Byrne, Barry J / Smith, Barbara K

    Journal of neurophysiology

    2021  Volume 126, Issue 2, Page(s) 351–360

    Abstract: Pompe disease (PD) is a neuromuscular disorder caused by a mutation in the acid alpha-glucosidase (GAA) gene. Patients with late-onset PD retain some GAA activity and present symptoms later in life, with fatality mainly associated with respiratory ... ...

    Abstract Pompe disease (PD) is a neuromuscular disorder caused by a mutation in the acid alpha-glucosidase (GAA) gene. Patients with late-onset PD retain some GAA activity and present symptoms later in life, with fatality mainly associated with respiratory failure. This case study presents diaphragm electrophysiology and a histological analysis of the brainstem, spinal cord, and diaphragm, from a male PD patient diagnosed with late-onset PD at age 35. The patient was wheelchair dependent by age 38, required nocturnal ventilation at age 40, 24-h noninvasive ventilation by age 43, and passed away from respiratory failure at age 54. Diaphragm electromyography recorded using indwelling "pacing" wires showed asynchronous bursting between the left and right diaphragm during brief periods of independent breathing. The synchrony declined over a 4-yr period preceding respiratory failure. Histological assessment indicated motoneuron atrophy in the medulla and rostral spinal cord. Hypoglossal (soma size: 421 ± 159 µm
    MeSH term(s) Brain Stem/pathology ; Brain Stem/physiopathology ; Diaphragm/physiopathology ; Glycogen Storage Disease Type II/pathology ; Glycogen Storage Disease Type II/physiopathology ; Humans ; Male ; Middle Aged ; Phrenic Nerve/pathology ; Phrenic Nerve/physiopathology ; Pulmonary Ventilation ; Spinal Cord/pathology ; Spinal Cord/physiopathology
    Language English
    Publishing date 2021-06-30
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80161-6
    ISSN 1522-1598 ; 0022-3077
    ISSN (online) 1522-1598
    ISSN 0022-3077
    DOI 10.1152/jn.00190.2021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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