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  1. Article ; Online: Artificial intelligence in medical science: a review.

    Bindra, Simrata / Jain, Richa

    Irish journal of medical science

    2023  

    Abstract: Artificial intelligence (AI) is a technique to make intelligent machines, mainly by using smart computer programs. It is based on a statistical analysis of data or machine learning. Using machine learning, software algorithms are designed according to ... ...

    Abstract Artificial intelligence (AI) is a technique to make intelligent machines, mainly by using smart computer programs. It is based on a statistical analysis of data or machine learning. Using machine learning, software algorithms are designed according to the desired application. These techniques are found to have the potential for advancement in the medical field by generating new and significant perceptions from the data generated using various types of healthcare tests. Artificial intelligence (AI) in medicine is of two types: virtual and physical. The virtual part decides the treatment using electronic health record systems using various sensors whereas the physical part assists robots to perform surgeries, implants, replacement of various organs, elderly care, etc. Using AI, a machine can examine various kinds of health care test reports in one go which could save the time, money, and increase the chances of the patient to be treated without any hassles. At present, artificial intelligence (AI) is used while deciding the treatment, and medications using various tools which could analyze X-rays, CT scans, MRIs, and any other data. During the COVID pandemic, there was a huge/massive demand for AI-supported technologies and many of those were created during that time. This study is focused on various applications of AI in healthcare.
    Language English
    Publishing date 2023-11-12
    Publishing country Ireland
    Document type Journal Article ; Review
    ZDB-ID 390895-1
    ISSN 1863-4362 ; 0021-1265
    ISSN (online) 1863-4362
    ISSN 0021-1265
    DOI 10.1007/s11845-023-03570-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Abnormal Eye Position.

    Bindra, Snehal / Pontell, Matthew E / O'Sick, Nicholas / Golinko, Michael S

    Pediatrics in review

    2023  Volume 44, Issue S1, Page(s) S48–S51

    Language English
    Publishing date 2023-09-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 774515-1
    ISSN 1526-3347 ; 0191-9601
    ISSN (online) 1526-3347
    ISSN 0191-9601
    DOI 10.1542/pir.2022-005742
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Environmental Enrichment Improved Cognitive Performance in Mice under Normoxia and Hypoxia.

    Bindra, Sahej / LaManna, Joseph C / Xu, Kui

    Advances in experimental medicine and biology

    2021  Volume 1269, Page(s) 329–333

    Abstract: The mammalian brain modulates its microvascular network to accommodate tissue energy demand in a process referred to as angioplasticity. There is an aging effect on cognitive function and adaptive responses to hypoxia. Hypoxia-induced angiogenesis is ... ...

    Abstract The mammalian brain modulates its microvascular network to accommodate tissue energy demand in a process referred to as angioplasticity. There is an aging effect on cognitive function and adaptive responses to hypoxia. Hypoxia-induced angiogenesis is delayed in the aging mouse brain. Additionally, it has been shown that environmental enrichment provides an environment that fosters increased physical activity and sensory stimulation for mice as compared to standard housing; this stimulation increases neuronal activity and consequently brain oxygen demand. In this study, we investigated the effect of environmental enrichment and chronic hypoxia on cognitive performance in the young (2-4 months old) and the aged mice (17-21 months old). Mice were placed in a non-enriched or an enriched environment for 4 weeks under normoxia followed by 3 weeks of hypobaric hypoxia (~0.4 atm, equivalent to 8% normobaric oxygen at sea level). Cognitive function was evaluated using the Y-maze and the novel object recognition tests in the enriched or non-enriched mice under normoxic or hypoxic conditions. In Y-maze, a high alternation rate is indicative of sustained cognition as the animals must remember which arm was entered last, so as not to re-enter it. Novel object recognition is based on the natural tendency of rodents to investigate a novel object instead of a familiar one; a higher novel object exploration rate is indicative of better cognitive function. The young mice showed a significantly higher alternation rate (%, 63 ± 7 vs. 48 ± 10, n = 8 and 10, respectively) in the Y-Maze test as compared to the aged mice. Under normoxia, the enriched mice showed an improved alternation rate (%, 63 ± 10, n = 10) in Y-Maze test and a higher novel object exploration rate (%, 68 ± 10 vs. 52 ± 10) compared to the non-enriched controls. Similar results were observed for both young and aged mice following hypoxic exposure. Our data suggests that environmental enrichment improved the cognitive performance in the young and aged mice under normoxic and hypoxic conditions.
    MeSH term(s) Aging ; Animals ; Brain ; Cognition ; Hypoxia ; Maze Learning ; Mice
    Language English
    Publishing date 2021-05-05
    Publishing country United States
    Document type Journal Article
    ISSN 2214-8019 ; 0065-2598
    ISSN (online) 2214-8019
    ISSN 0065-2598
    DOI 10.1007/978-3-030-48238-1_52
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Converting waste to energy: Production and characterization of biodiesel from Chlorella pyrenoidosa grown in a medium designed from waste

    Bindra, Sunny / Kulshrestha, Saurabh

    Renewable energy. 2019 Nov., v. 142

    2019  

    Abstract: Biodiesel has been reported as renewable, green fuel with better engine-emission properties and microalgae (like C.pyrenoidosa) derived biodiesel is a step towards the sustainable supply of liquid fuel to drive the world economies. In the present ... ...

    Abstract Biodiesel has been reported as renewable, green fuel with better engine-emission properties and microalgae (like C.pyrenoidosa) derived biodiesel is a step towards the sustainable supply of liquid fuel to drive the world economies. In the present investigation, Biowaste [Dairy wastewater (DWW) and rice straw hydrolysate (RSH)] was used as natural feedstock for the growth of C. pyrenoidosa. The better yield was obtained by using DWW as media for the growth of microalgae. The biodiesel produced was composed of high molecular weight fatty acid methyl esters (FAME), thus confirming its purity. Physico-chemical properties of the biodiesel produced were analyzed and compared with the petrodiesel and with standard analytical methods (ASTM-D6751 and EN 14214:2010). The brake thermal efficiency (BTE) of 42.23%, the calorific value of 41.865 MJ/kg and brake power (BP) 39.99 kW was obtained for the biodiesel produced and has been found to be higher but statistically non-significant in comparison to petrodiesel. However, statistically significant reduction in emission (40–50%) and reduction in CO2 (50–60%) was found in case of biodiesel as compared to petrodiesel. The data presented clearly demonstrates that the engine performance parameters and emission parameters of the biodiesel produced were better than the conventional petrodiesel.
    Keywords analytical methods ; biodiesel ; carbon dioxide ; Chlorella pyrenoidosa ; diesel fuel ; energy ; fatty acid methyl esters ; feedstocks ; hydrolysates ; liquids ; microalgae ; molecular weight ; rice straw ; wastewater
    Language English
    Dates of publication 2019-11
    Size p. 415-425.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 2001449-1
    ISSN 0960-1481
    ISSN 0960-1481
    DOI 10.1016/j.renene.2019.04.104
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Comparative Somatic Variant Analysis of a Rare Case with Concurrent Oral Leukoplakia and Oral Submucosal Fibrosis.

    Anne, Anuhya / Bindra, Sukhvinder / Reddy, Kanapuram V R / Gummanur, Madhusudhana R / Mohan, Kommu N

    Cytogenetic and genome research

    2022  , Page(s) 1–7

    Abstract: Oral leukoplakia (OL) and oral submucosal fibrosis (OSMF) are precancerous conditions with common etiologies but with different risks for oral cancer (OC) progression. In rare cases, both conditions occur in the same patient and provide an opportunity ... ...

    Abstract Oral leukoplakia (OL) and oral submucosal fibrosis (OSMF) are precancerous conditions with common etiologies but with different risks for oral cancer (OC) progression. In rare cases, both conditions occur in the same patient and provide an opportunity for understanding the common and distinctive variants upon exposure of genetically identical normal cells to the same carcinogen(s). We performed exome sequencing of a patient with OL (hyperplasia, but no dysplasia) and OSMF (grade II) in the opposite cheeks using blood DNA as the reference genome. The overall somatic variant burden was higher in OSMF than OL, but opposite in the case of copy number alterations. OL-specific variants were enriched in genes associated with DNA repair, cell division/cell cycle checkpoint pathways, whereas in OSMF, extracellular matrix-receptor interaction was mainly affected. The proportions of variants in cancer driver genes and cancer driver mutations were similar in both cases indicating no difference in the potential risk associated with the two conditions at the stages sampled. Future studies on rare cases similar to the one described in this report will help in understanding the molecular basis of differences associated with OL and OSMF and shared processes accompanying OC progression.
    Language English
    Publishing date 2022-10-21
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2087824-2
    ISSN 1424-859X ; 1424-8581
    ISSN (online) 1424-859X
    ISSN 1424-8581
    DOI 10.1159/000526919
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 512: Show issues Location:
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  6. Article: Unraveling the genetics of heat tolerance in chickpea landraces (

    Danakumara, Thippeswamy / Kumar, Neeraj / Patil, Basavanagouda Siddanagouda / Kumar, Tapan / Bharadwaj, Chellapilla / Jain, Pradeep Kumar / Nimmy, Manduparambil Subramanian / Joshi, Nilesh / Parida, Swarup Kumar / Bindra, Shayla / Kole, Chittaranjan / Varshney, Rajeev K

    Frontiers in plant science

    2024  Volume 15, Page(s) 1376381

    Abstract: Chickpea, being an important grain legume crop, is often confronted with the adverse effects of high temperatures at the reproductive stage of crop growth, drastically affecting yield and overall productivity. The current study deals with an extensive ... ...

    Abstract Chickpea, being an important grain legume crop, is often confronted with the adverse effects of high temperatures at the reproductive stage of crop growth, drastically affecting yield and overall productivity. The current study deals with an extensive evaluation of chickpea genotypes, focusing on the traits associated with yield and their response to heat stress. Notably, we observed significant variations for these traits under both normal and high-temperature conditions, forming a robust basis for genetic research and breeding initiatives. Furthermore, the study revealed that yield-related traits exhibited high heritability, suggesting their potential suitability for marker-assisted selection. We carried out single-nucleotide polymorphism (SNP) genotyping using the genotyping-by-sequencing (GBS) method for a genome-wide association study (GWAS). Overall, 27 marker-trait associations (MTAs) linked to yield-related traits, among which we identified five common MTAs displaying pleiotropic effects after applying a stringent Bonferroni-corrected p-value threshold of <0.05 [-log
    Language English
    Publishing date 2024-03-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2024.1376381
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Traumatic Bone Cyst of Mandible: A Case Report of Rare Entity and Review of Literature.

    Bindra, Sukhvinder / Jadaun, Gargi / Jois, Harshvardhan S / Sen, Prabuddh

    Contemporary clinical dentistry

    2020  Volume 10, Issue 1, Page(s) 3–8

    Abstract: The traumatic bone cyst was first described by Lucas in 1929 and later by Rushton. A solitary bone cyst (SBC) is a nonneoplastic osseous lesion affecting ≥95% of the metaphyses of long bones such as the proximal humerus and femur. The incidence of cyst ... ...

    Abstract The traumatic bone cyst was first described by Lucas in 1929 and later by Rushton. A solitary bone cyst (SBC) is a nonneoplastic osseous lesion affecting ≥95% of the metaphyses of long bones such as the proximal humerus and femur. The incidence of cyst affecting the jaws is 1% of all the cyst. About 89% of the lesion occurs in the mandible and 11% in the maxilla. Majority of the lesions occur in the posterior mandible, especially in the premolar-molar region. In this case report, we are presenting one such case of multiple lesions of SBC in mandible with systematic review of the literature.
    Language English
    Publishing date 2020-01-13
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 2582352-8
    ISSN 0976-2361 ; 0976-237X
    ISSN (online) 0976-2361
    ISSN 0976-237X
    DOI 10.4103/ccd.ccd_489_18
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Phenotypic evaluation of genetic variability and selection of yield contributing traits in chickpea recombinant inbred line population under high temperature stress.

    Kushwah, Ashutosh / Bhatia, Dharminder / Singh, Gurpreet / Singh, Inderjit / Bindra, Shayla / Vij, Suruchi / Singh, Sarvjeet

    Physiology and molecular biology of plants : an international journal of functional plant biology

    2021  Volume 27, Issue 4, Page(s) 747–767

    Abstract: Heat is a major abiotic stress that drastically reduces chickpea yield. This study aimed to identify heat-responsive traits to sustain crop productivity by screening a recombinant inbred line (RILs) population at two locations in India (Ludhiana and ... ...

    Abstract Heat is a major abiotic stress that drastically reduces chickpea yield. This study aimed to identify heat-responsive traits to sustain crop productivity by screening a recombinant inbred line (RILs) population at two locations in India (Ludhiana and Faridkot). The RIL population was derived from an inter-specific cross between heat-tolerant genotype GPF 2 (
    Supplementary information: The online version contains supplementary material available at 10.1007/s12298-021-00977-5.
    Language English
    Publishing date 2021-04-02
    Publishing country India
    Document type Journal Article
    ZDB-ID 2487126-6
    ISSN 0974-0430 ; 0971-5894
    ISSN (online) 0974-0430
    ISSN 0971-5894
    DOI 10.1007/s12298-021-00977-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Identification of promising chickpea interspecific derivatives for agro-morphological and major biotic traits.

    Singh, Mohar / Kumar, Tapan / Sood, Salej / Malhotra, Nikhil / Rani, Upasana / Singh, Sarvjeet / Singh, Inderjit / Bindra, Shayla / Kumar, Sanjeev / Kumar, Sandeep

    Frontiers in plant science

    2022  Volume 13, Page(s) 941372

    Abstract: ... The ... ...

    Abstract The wild
    Language English
    Publishing date 2022-08-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2022.941372
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Phenotypic evaluation of agronomic and root related traits for drought tolerance in recombinant inbred line population derived from a chickpea cultivar (

    Kushwah, Ashutosh / Bhatia, Dharminder / Singh, Gurpreet / Singh, Inderjit / Vij, Suruchi / Bindra, Shayla / Siddique, Kadambot H M / Nayyar, Harsh / Singh, Sarvjeet

    Physiology and molecular biology of plants : an international journal of functional plant biology

    2022  Volume 28, Issue 7, Page(s) 1437–1452

    Abstract: Drought is a major abiotic stress that drastically reduces chickpea yields. The present study was aimed to identify drought-responsive traits in chickpea by screening a recombinant inbred line population derived from an inter-specific cross between ... ...

    Abstract Drought is a major abiotic stress that drastically reduces chickpea yields. The present study was aimed to identify drought-responsive traits in chickpea by screening a recombinant inbred line population derived from an inter-specific cross between drought cultivar of GPF2 (
    Supplementary information: The online version contains supplementary material available at 10.1007/s12298-022-01218-z.
    Language English
    Publishing date 2022-08-13
    Publishing country India
    Document type Journal Article
    ZDB-ID 2487126-6
    ISSN 0974-0430 ; 0971-5894
    ISSN (online) 0974-0430
    ISSN 0971-5894
    DOI 10.1007/s12298-022-01218-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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