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Book: Soil contamination to land restoration

Bini, Claudio

(Air, water and soil pollution science and technology series)

2010

Author's details	Claudio Bini
Series title	Air, water and soil pollution science and technology series
Language	English
Size	X, 68 : Ill., graph. Darst.
Publisher	Nova Science Publ
Publishing place	New York, NY
Publishing country	United States
Document type	Book
HBZ-ID	HT016200035
ISBN	978-1-60876-853-0 ; 1-60876-853-8
Database	Catalogue ZB MED Nutrition, Environment, Agriculture

In stock of ZB MED Bonn / Germany

Shelf mark	Loan status	Location
118/421	available for loan (reading room)	Freihandmagazin (U1)

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Article ; Online: Radiation Overuse in Intensive Care Units.

Zanon, Chiara / Bini, Costanza / Toniolo, Alessandro / Benetti, Tommaso / Quaia, Emilio

Tomography (Ann Arbor, Mich.)

2024 Volume 10, Issue 2, Page(s) 193–202

Abstract: Radiological imaging is essential for acute patient management in Intensive Care Units (ICUs); however, it introduces the risk of exposure to ionizing radiation. This review synthesizes research on radiation exposure in ICU settings, highlighting its ... ...

Abstract	Radiological imaging is essential for acute patient management in Intensive Care Units (ICUs); however, it introduces the risk of exposure to ionizing radiation. This review synthesizes research on radiation exposure in ICU settings, highlighting its rise during the COVID-19 pandemic and the rise in repetitive imaging. Our analysis extends to radiation safety thresholds, revealing that some ICU patients exceed the diagnostic reference level, emphasizing the need to balance diagnostic utility against potential long-term risks, such as cancer. Prospective studies have demonstrated an increase in the median cumulative effective dose in patients with trauma over time, prompting calls for improved awareness and monitoring. Moreover, innovative dose-reduction strategies and optimized protocols, especially in neuro-ICUs, promise to mitigate these risks. This review highlights the essential but risky role of radiological imaging in critical care. It advocates for rigorous radiation management protocols to safeguard patient health while ensuring the continuity of high-quality medical care.
MeSH term(s)	Humans ; Prospective Studies ; Pandemics ; Intensive Care Units ; Diagnostic Imaging ; COVID-19
Language	English
Publishing date	2024-01-29
Publishing country	Switzerland
Document type	Journal Article ; Review
ISSN	2379-139X
ISSN (online)	2379-139X
DOI	10.3390/tomography10020015
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: How patients with insomnia interpret and respond to the consensus sleep diary: a cognitive interview study.

Bini, Christina / Hjelm, Carina / Hellström, Amanda / Årestedt, Kristofer / Broström, Anders / Sandlund, Christina

Journal of patient-reported outcomes

2024 Volume 8, Issue 1, Page(s) 19

Abstract: Objective/background: The Consensus Sleep Diary (CSD) is widely used to assess subjective sleep. Psychometric evaluations and focus-groups support its validity and clinical usefulness, but further research into its validity is needed. The aim of the ... ...

Abstract	Objective/background: The Consensus Sleep Diary (CSD) is widely used to assess subjective sleep. Psychometric evaluations and focus-groups support its validity and clinical usefulness, but further research into its validity is needed. The aim of the study was to evaluate a Swedish translation of the CSD regarding test content and response processes in patients with insomnia. Patients/methods: In connection with translating the CSD into Swedish, we used cognitive interviewing to evaluate test content and the response process, that is, how people make decisions when responding to survey items. Cognitive interviews were conducted with 13 primary health care patients with insomnia disorder (mean age, 49 years; SD 15.5). Iterative, reparative analysis was used to investigate test content. Descriptive deductive analysis was used to investigate interview transcripts for the themes of the cognitive model: comprehension, retrieval, decision process, and judgement. Together, the themes explain the response process when responding to a patient-reported outcome measure. Results: The overall comprehension of the CSD could be affected by poor adherence to the instructions (comprehension). Patients had difficulty with recall if they did not complete the diary immediately in the morning and just before bedtime (retrieval). They could have problems deciding how to respond to certain items because they imbued sleep-related concepts with extra meaning (decision process), and had trouble finding response alternatives nuanced enough to describe their experience of sleep and tiredness (judgement). Conclusions: This study contributes knowledge on how the instrument is perceived and used by care-seeking patients with insomnia. In this context, the CSD exhibits known flaws such as memory lapses if the diary is not filled in directly in the morning. To increase the accuracy of patients' responses, therapists should support patients in reading the instructions.
MeSH term(s)	Humans ; Middle Aged ; Sleep Initiation and Maintenance Disorders/diagnosis ; Consensus ; Sleep ; Qualitative Research ; Cognition
Language	English
Publishing date	2024-02-20
Publishing country	Germany
Document type	Journal Article
ISSN	2509-8020
ISSN (online)	2509-8020
DOI	10.1186/s41687-024-00695-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The Link between Prostanoids and Cardiovascular Diseases.

Beccacece, Livia / Abondio, Paolo / Bini, Carla / Pelotti, Susi / Luiselli, Donata

International journal of molecular sciences

2023 Volume 24, Issue 4

Abstract: Cardiovascular diseases are the leading cause of global deaths, and many risk factors contribute to their pathogenesis. In this context, prostanoids, which derive from arachidonic acid, have attracted attention for their involvement in cardiovascular ... ...

Abstract	Cardiovascular diseases are the leading cause of global deaths, and many risk factors contribute to their pathogenesis. In this context, prostanoids, which derive from arachidonic acid, have attracted attention for their involvement in cardiovascular homeostasis and inflammatory processes. Prostanoids are the target of several drugs, but it has been shown that some of them increase the risk of thrombosis. Overall, many studies have shown that prostanoids are tightly associated with cardiovascular diseases and that several polymorphisms in genes involved in their synthesis and function increase the risk of developing these pathologies. In this review, we focus on molecular mechanisms linking prostanoids to cardiovascular diseases and we provide an overview of genetic polymorphisms that increase the risk for cardiovascular disease.
MeSH term(s)	Humans ; Cardiovascular Diseases ; Prostaglandins ; Cardiovascular System ; Thrombosis ; Risk Factors
Chemical Substances	Prostaglandins
Language	English
Publishing date	2023-02-20
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms24044193
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Potential Benefits of Photon-Counting CT in Dental Imaging: A Narrative Review.

Zanon, Chiara / Pepe, Alessia / Cademartiri, Filippo / Bini, Costanza / Maffei, Erica / Quaia, Emilio / Stellini, Edoardo / Di Fiore, Adolfo

Journal of clinical medicine

2024 Volume 13, Issue 8

Abstract: Background/Objectives: ...

Abstract	Background/Objectives:
Language	English
Publishing date	2024-04-22
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm13082436
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Medico-legal implications of dog bite injuries: A systematic review.

Giovannini, Elena / Roccaro, Mariana / Peli, Angelo / Bianchini, Simone / Bini, Carla / Pelotti, Susi / Fais, Paolo

Forensic science international

2023 Volume 352, Page(s) 111849

Abstract: Dog bites pose a significant global public health issue and are the most common type of injury caused by animals. While most dog bites result in minor harm, they can also lead to severe or even fatal consequences. In cases involving serious injury or ... ...

Abstract	Dog bites pose a significant global public health issue and are the most common type of injury caused by animals. While most dog bites result in minor harm, they can also lead to severe or even fatal consequences. In cases involving serious injury or death, forensic pathologists investigate various aspects, including the crime scene, the injuries sustained by the victim, and the characteristics of the dog suspected to have caused the bite. The aim of this study is to provide a systematic review of the literature on the medical-legal implications of dog bites in forensic practice, in order to recognize the dog bite victim features, the injuries and their consequences related to, and to identify the offending dogs. The literature search was performed using PubMed, Scopus and Web of Science from January 1980 to March 2023. Eligible studies have investigated issues of interest to forensic medicine about dog bites to humans. A total of 116 studies met the inclusion criteria and were included in the review and they were organized and discussed by issue of interest (biting dog features, dog bite victim features, anatomical distribution of dog bites, injuries related to dog bites, cause of death, bite features, dog identification and post-mortem dog depredation). The findings of this systematic review highlight the importance of bite mark analysis in reconstructing the events leading to the attack and identifying the dog responsible. In medical forensic evaluations of dog bite cases, a multidisciplinary approach is crucial. This approach involves thorough analysis of the crime scene, identification of risk factors, examination of dog characteristics, and assessment of the victim's injuries. By combining expertise from both human and veterinary forensic fields, a comprehensive understanding can be achieved in dog bite cases.
MeSH term(s)	Humans ; Dogs ; Animals ; Bites and Stings ; Forensic Medicine ; Crime ; Risk Factors ; Autopsy
Language	English
Publishing date	2023-09-27
Publishing country	Ireland
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	424042-x
ISSN	1872-6283 ; 0379-0738
ISSN (online)	1872-6283
ISSN	0379-0738
DOI	10.1016/j.forsciint.2023.111849
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Article ; Online: A Genome-Wide Analysis of a Sudden Cardiac Death Cohort: Identifying Novel Target Variants in the Era of Molecular Autopsy.

Beccacece, Livia / Abondio, Paolo / Giorgetti, Arianna / Bini, Carla / Pelletti, Guido / Luiselli, Donata / Pelotti, Susi

Genes

2023 Volume 14, Issue 6

Abstract: Sudden cardiac death (SCD) is an unexpected natural death due to cardiac causes, usually happening within one hour of symptom manifestation or in individuals in good health up to 24 h before the event. Genomic screening has been increasingly applied as a ...

Abstract	Sudden cardiac death (SCD) is an unexpected natural death due to cardiac causes, usually happening within one hour of symptom manifestation or in individuals in good health up to 24 h before the event. Genomic screening has been increasingly applied as a useful approach to detecting the genetic variants that potentially contribute to SCD and helping the evaluation of SCD cases in the post-mortem setting. Our aim was to identify the genetic markers associated with SCD, which might enable its target screening and prevention. In this scope, a case-control analysis through the post-mortem genome-wide screening of 30 autopsy cases was performed. We identified a high number of novel genetic variants associated with SCD, of which 25 polymorphisms were consistent with a previous link to cardiovascular diseases. We ascertained that many genes have been already linked to cardiovascular system functioning and diseases and that the metabolisms most implicated in SCD are the lipid, cholesterol, arachidonic acid, and drug metabolisms, suggesting their roles as potential risk factors. Overall, the genetic variants pinpointed herein might be useful markers of SCD, but the novelty of these results requires further investigations.
MeSH term(s)	Humans ; Autopsy ; Death, Sudden, Cardiac/etiology
Language	English
Publishing date	2023-06-15
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2527218-4
ISSN	2073-4425 ; 2073-4425
ISSN (online)	2073-4425
ISSN	2073-4425
DOI	10.3390/genes14061265
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Article ; Online: Sub-chronic exposure of Oreochromis niloticus to environmentally relevant concentrations of smaller microplastics: Accumulation and toxico-physiological responses.

Das, Bini C / Ramanan P, Aparna / Gorakh, Satkar Sagar / Pillai, Devika / Vattiringal Jayadradhan, Rejish Kumar

Journal of hazardous materials

2023 Volume 458, Page(s) 131916

Abstract: This study assesses the accumulation and toxic effects of environmentally relevant concentrations (0.01, 0.1 and 1 mg/L) of polystyrene MPs (1 µm) in Oreochromis niloticus (Nile tilapia) for 14 days. The results showed that 1 µm PS-MPs accumulated in the ...

Abstract	This study assesses the accumulation and toxic effects of environmentally relevant concentrations (0.01, 0.1 and 1 mg/L) of polystyrene MPs (1 µm) in Oreochromis niloticus (Nile tilapia) for 14 days. The results showed that 1 µm PS-MPs accumulated in the intestine, gills, liver, spleen, muscle, gonad and brain. RBC, Hb and HCT showed a significant decline, while WBC and PLT showed a significant increase after the exposure. Glucose, total protein, A/G ratio, SGOT, SGPT and ALP showed significant increments in 0.1 and 1 mg/L of PS-MPs treated groups. The increase in cortisol level and upregulation of HSP70 gene expression in response to MPs exposure indicate MPs-mediated stress in tilapia. MPs-induced oxidative stress is evident from reduced SOD activity, increased MDA levels and upregulated P53 gene expression. The immune response was enhanced by inducing respiratory burst activity, MPO activity and serum TNF-α and IgM levels. MPs exposure also led to down-regulation of CYP1A gene and decreased AChE activity, GNRH and vitellogenin levels, indicating the toxicity of MPs on the cellular detoxification mechanism, nervous and reproductive systems. The present study highlights the tissue accumulation of PS-MP and its effects on hematological, biochemical, immunological and physiological responses in tilapia with low environmentally relevant concentrations.
MeSH term(s)	Animals ; Cichlids/metabolism ; Microplastics/metabolism ; Plastics/metabolism ; Oxidative Stress ; Antioxidants/metabolism ; Tilapia/metabolism ; Polystyrenes/metabolism ; Water Pollutants, Chemical/analysis
Chemical Substances	Microplastics ; Plastics ; Antioxidants ; Polystyrenes ; Water Pollutants, Chemical
Language	English
Publishing date	2023-06-22
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1491302-1
ISSN	1873-3336 ; 0304-3894
ISSN (online)	1873-3336
ISSN	0304-3894
DOI	10.1016/j.jhazmat.2023.131916
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Impact on touch DNA of an alcohol-based hand sanitizer used in COVID-19 prevention.

Bini, Carla / Giorgetti, Arianna / Fazio, Giulia / Amurri, Sara / Pelletti, Guido / Pelotti, Susi

International journal of legal medicine

2023 Volume 137, Issue 3, Page(s) 645–653

Abstract: In the last years, forensic research has been focused on touch DNA in order to improve its evidential value in criminal activity investigations as well as to understand the variables impacting touch DNA. One of the emerging variables is represented by ... ...

Abstract	In the last years, forensic research has been focused on touch DNA in order to improve its evidential value in criminal activity investigations as well as to understand the variables impacting touch DNA. One of the emerging variables is represented by the use of alcohol-based sanitizers, which was suggested for hand hygiene during the COVID-19 pandemic. The aims of the present study were to assess the effect of a hand sanitizer on touch DNA deposition, transfer, and recovery and also to evaluate STR typing success, quality of DNA profiles, and personal identification. Before and after the use of an alcohol-based hand sanitizer, 20 volunteers deposited on glass surfaces 120 fingerprints, containing skin-derived or salivary DNA. Samples were quantified by real-time quantitative PCR (q-PCR), and 76 samples yielding > 15 pg/μl were typed for 21 autosomal STRs by GlobalFiler® PCR Amplification Kit. DNA profiles were classified into single source, mixed, and inconclusive profiles, and a LR assessment was performed by comparison to the reference samples using LRmix Studio software. After the use of hand sanitizer, samples yielded lower quantities of recovered transferred DNA, especially considering samples containing salivary DNA (p < 0.05 by Friedman test). All the 76 amplified samples (63.3% of the total) showed at least 10 typed loci, and 83-100% of profiles were consistent with the reference ones on the basis of a LR value ≥ 10
MeSH term(s)	Humans ; Touch ; Hand Sanitizers ; Pandemics ; DNA Fingerprinting/methods ; Microsatellite Repeats ; COVID-19/prevention & control ; Real-Time Polymerase Chain Reaction ; Ethanol ; DNA/genetics
Chemical Substances	Hand Sanitizers ; Ethanol (3K9958V90M) ; DNA (9007-49-2)
Language	English
Publishing date	2023-02-24
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1055109-8
ISSN	1437-1596 ; 0937-9827
ISSN (online)	1437-1596
ISSN	0937-9827
DOI	10.1007/s00414-023-02979-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Recombulator-X: A fast and user-friendly tool for estimating X chromosome recombination rates in forensic genetics.

Aneli, Serena / Fariselli, Piero / Chierto, Elena / Bini, Carla / Robino, Carlo / Birolo, Giovanni

PLoS computational biology

2023 Volume 19, Issue 9, Page(s) e1011474

Abstract: Genetic markers (especially short tandem repeats or STRs) located on the X chromosome are a valuable resource to solve complex kinship cases in forensic genetics in addition or alternatively to autosomal STRs. Groups of tightly linked markers are ... ...

Abstract	Genetic markers (especially short tandem repeats or STRs) located on the X chromosome are a valuable resource to solve complex kinship cases in forensic genetics in addition or alternatively to autosomal STRs. Groups of tightly linked markers are combined into haplotypes, thus increasing the discriminating power of tests. However, this approach requires precise knowledge of the recombination rates between adjacent markers. The International Society of Forensic Genetics recommends that recombination rate estimation on the X chromosome is performed from pedigree genetic data while taking into account the confounding effect of mutations. However, implementations that satisfy these requirements have several drawbacks: they were never publicly released, they are very slow and/or need cluster-level hardware and strong computational expertise to use. In order to address these key concerns we developed Recombulator-X, a new open-source Python tool. The most challenging issue, namely the running time, was addressed with dynamic programming techniques to greatly reduce the computational complexity of the algorithm. Compared to the previous methods, Recombulator-X reduces the estimation times from weeks or months to less than one hour for typical datasets. Moreover, the estimation process, including preprocessing, has been streamlined and packaged into a simple command-line tool that can be run on a normal PC. Where previous approaches were limited to small panels of STR markers (up to 15), our tool can handle greater numbers (up to 100) of mixed STR and non-STR markers. In conclusion, Recombulator-X makes the estimation process much simpler, faster and accessible to researchers without a computational background, hopefully spurring increased adoption of best practices.
Language	English
Publishing date	2023-09-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2193340-6
ISSN	1553-7358 ; 1553-734X
ISSN (online)	1553-7358
ISSN	1553-734X
DOI	10.1371/journal.pcbi.1011474
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