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  1. Article ; Online: Engaging patients and stakeholders to identify a research agenda to support social determinants of health (SDOH) screening and intervention initiatives in community pharmacy.

    Parikh, Megha A / Selvarajah, Shalini / Castora-Binkley, Melissa / Angove, Rebekah S M

    Journal of the American Pharmacists Association : JAPhA

    2024  Volume 64, Issue 2, Page(s) 592–595.e1

    MeSH term(s) Humans ; Pharmacies ; Social Determinants of Health
    Language English
    Publishing date 2024-01-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2118585-2
    ISSN 1544-3450 ; 1544-3191 ; 1086-5802
    ISSN (online) 1544-3450
    ISSN 1544-3191 ; 1086-5802
    DOI 10.1016/j.japh.2023.12.022
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    Zs.A 1042: Show issues Location:
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  2. Article ; Online: Impact and Continued Relevance of Medication Adherence Measurement.

    Shirley, Ben / Castora-Binkley, Melissa / Hines, Lisa

    Population health management

    2022  Volume 25, Issue 4, Page(s) 575–578

    MeSH term(s) Humans ; Medicare Part D ; Medication Adherence ; Medication Therapy Management ; United States
    Language English
    Publishing date 2022-04-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2454546-6
    ISSN 1942-7905 ; 1942-7891
    ISSN (online) 1942-7905
    ISSN 1942-7891
    DOI 10.1089/pop.2022.0022
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    Zs.A 5170: Show issues Location:
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  3. Article ; Online: The pathobiology of select adolescent young adult lymphomas.

    Steidl, Christian / Kridel, Robert / Binkley, Michael / Morton, Lindsay M / Chadburn, Amy

    EJHaem

    2023  Volume 4, Issue 4, Page(s) 892–901

    Abstract: Lymphoid cancers are among the most frequent cancers diagnosed in adolescents and young adults (AYA), ranging from approximately 30%-35% of cancer diagnoses in adolescent patients (age 10-19) to approximately 10% in patients aged 30-39 years. Moreover, ... ...

    Abstract Lymphoid cancers are among the most frequent cancers diagnosed in adolescents and young adults (AYA), ranging from approximately 30%-35% of cancer diagnoses in adolescent patients (age 10-19) to approximately 10% in patients aged 30-39 years. Moreover, the specific distribution of lymphoid cancer types varies by age with substantial shifts in the subtype distributions between pediatric, AYA, adult, and older adult patients. Currently, biology studies specific to AYA lymphomas are rare and therefore insight into age-related pathogenesis is incomplete. This review focuses on the paradigmatic epidemiology and pathogenesis of select lymphomas, occurring in the AYA patient population. With the example of posttransplant lymphoproliferative disorders, nodular lymphocyte-predominant Hodgkin lymphoma, follicular lymphoma (incl. pediatric-type follicular lymphoma), and mediastinal lymphomas (incl. classic Hodgkin lymphoma, primary mediastinal large B cell lymphoma and mediastinal gray zone lymphoma), we here illustrate the current state-of-the-art in lymphoma classification, recent molecular insights including genomics, and translational opportunities. To improve outcome and quality of life, international collaboration in consortia dedicated to AYA lymphoma is needed to overcome challenges related to siloed biospecimens and data collections as well as to develop studies designed specifically for this unique population.
    Language English
    Publishing date 2023-09-29
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2688-6146
    ISSN (online) 2688-6146
    DOI 10.1002/jha2.785
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  4. Article: Cerebral arterial gas embolism in a patient with hypoplastic left heart syndrome treated with emergent hyperbaric oxygen: case report.

    Binkley, Mark / Kelly, Matthew / Hardy, Kevin

    Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc

    2020  Volume 47, Issue 3, Page(s) 431–434

    Abstract: A 30-year-old female with a history of seizure disorder and hypoplastic left heart syndrome treated with a Norwood procedure in 1986 followed by a modified non-fenestrated Fontan (Left SVC to IVC to pulmonary arteries) with a known baffle leak presented ... ...

    Abstract A 30-year-old female with a history of seizure disorder and hypoplastic left heart syndrome treated with a Norwood procedure in 1986 followed by a modified non-fenestrated Fontan (Left SVC to IVC to pulmonary arteries) with a known baffle leak presented to the emergency department. On day of presentation, the patient became unresponsive, with perioral cyanosis, rightward gaze and a left facial droop near the end of a platelet transfusion. An emergent non-contrast head CT revealed intracranial air in the right MCA distribution. She was taken to the hyperbaric chamber and was treated with a U.S. Navy Table 6 in a multiplace chamber with no extensions. Ten minutes into the treatment patient became more alert and spontaneously asked questions. The following day she was treated with a U.S. Navy Table 5. Patient had repeat CT of the head, which showed resolution of intracerebral gas and small areas of ischemia in right frontal lobe and right caudate. On hospital day five neurologic exam was normal, with 5/5 strength and no residual deficits. Treating the patient was a concern because patient has a single ventricle, in which the pulmonary artery is connected directly to the vena cava. There is very little data regarding the effects of hyperbaric oxygen (HBO2)therapy on single-ventricle physiology. Only two case reports of three pediatric patients treated with HBO2 for CAGE in a similar setting are known. In these cases the patients had improvements in their symptoms following HBO2. These cases and ours indicate HBO2 is feasible and indicated for CAGE in patients with cyanotic congenital heart disease.
    MeSH term(s) Adult ; Embolism, Air/diagnostic imaging ; Embolism, Air/therapy ; Emergencies ; Female ; Fontan Procedure ; Humans ; Hyperbaric Oxygenation/methods ; Hypoplastic Left Heart Syndrome/complications ; Hypoplastic Left Heart Syndrome/surgery ; Intracranial Embolism/diagnostic imaging ; Intracranial Embolism/therapy ; Tomography, X-Ray Computed
    Language English
    Publishing date 2020-09-25
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1154414-4
    ISSN 1066-2936
    ISSN 1066-2936
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    Zs.A 1069: Show issues Location:
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  5. Article: Survey of Expert Opinion Regarding Peri-operative Management of Shoulder Arthroplasty.

    Pressman, Zachary / Rogozinski, Jonathan / Flanigan, Trenden / Srinivas, Mukund / Froehle, Andrew / Srikumaran, Uma / Binkley, Matthew

    The archives of bone and joint surgery

    2022  Volume 10, Issue 9, Page(s) 816–817

    Language English
    Publishing date 2022-10-05
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2782053-1
    ISSN 2345-461X ; 2345-4644
    ISSN (online) 2345-461X
    ISSN 2345-4644
    DOI 10.22038/ABJS.2022.59576.2940
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  6. Article ; Online: Trends in Racial and Ethnic Diversity in Vascular Neurology Fellowships From 2006 to 2018: A Cross-Sectional Analysis.

    Das, Saurav / Farkas, Nathan / Binkley, Michael / Williams, Jonathan / Ebong, Ima M / Akca, Ozan / Ford, Andria / Van Stavern, Renee / Zazulia, Allyson

    Stroke

    2022  Volume 53, Issue 3, Page(s) 867–874

    Abstract: Background: Workforce diversity in vascular neurology is a crucial component of reducing disparities in stroke care and outcomes. The objective of this study is to describe trends in the racial and ethnic diversity of neurology residents pursuing ... ...

    Abstract Background: Workforce diversity in vascular neurology is a crucial component of reducing disparities in stroke care and outcomes. The objective of this study is to describe trends in the racial and ethnic diversity of neurology residents pursuing vascular neurology fellowship and propose an actionable plan for improvement.
    Methods: This was a cross-sectional study of race/ethnicity of neurology residents and vascular neurology fellows using published Graduate Medical Education census reports from 2006, when race/ethnicity data were first included, to 2018. Percentage of trainees underrepresented in medicine are reported for 3-year epochs and were analyzed using the Cochran-Armitage test (χ
    Results: Across the study period, underrepresented in medicine representation has not changed significantly among all neurology residents and subspecialty fellows (11.9% in 2006-2009; 12.5% in 2015-2018,
    Conclusions: Racial/ethnic underrepresentation among all neurology residents as well as those pursuing vascular neurology fellowship has persisted across the study period. Concerted efforts should be pursued to increase diversity in neurology residents and vascular neurology fellowship training.
    MeSH term(s) Cross-Sectional Studies ; Education, Medical, Graduate ; Ethnicity ; Fellowships and Scholarships ; Humans ; Internship and Residency ; Racial Groups ; United States
    Language English
    Publishing date 2022-02-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.121.035481
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    Zs.A 448: Show issues Location:
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  7. Article ; Online: It is time for a new comprehensive medication review quality measure.

    Castora-Binkley, Melissa / Hines, Lisa / Vaffis, Shannon / Dhatt, Harman / Anderson, Elizabeth / Le, Darlena / Black, Heather / Campbell, Patrick J / Kolobova, Irina / Nelson, Mel / Axon, David R / Warholak, Terri

    Journal of managed care & specialty pharmacy

    2023  Volume 29, Issue 6, Page(s) 680–684

    Abstract: Medication therapy management (MTM) services include comprehensive medication reviews (CMRs), which have been completed with millions of patients since their inception in the United States. The current MTM quality measure focuses on whether CMRs were ... ...

    Abstract Medication therapy management (MTM) services include comprehensive medication reviews (CMRs), which have been completed with millions of patients since their inception in the United States. The current MTM quality measure focuses on whether CMRs were completed (ie, the CMR completion rate). However, this process measure does not assess quality of care, or patient-reported or other outcomes of CMRs, and, therefore, does not reward MTM providers for improving health outcomes. In this viewpoint article, we present 3 reasons that shape our argument for new MTM quality measures and offer recommendations on next steps to achieve this.
    MeSH term(s) Humans ; Female ; United States ; Quality Indicators, Health Care ; Medication Review ; Medication Therapy Management ; Pharmaceutical Services ; Pharmacies
    Language English
    Publishing date 2023-05-29
    Publishing country United States
    Document type Journal Article
    ISSN 2376-1032
    ISSN (online) 2376-1032
    DOI 10.18553/jmcp.2023.29.6.680
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  8. Article ; Online: Home health agency adoption of quality improvement activities and association with performance.

    Shetty, Kanaka D / Robbins, Michael W / Saliba, Debra / Campbell, Kyle N / Castora-Binkley, Melissa / Damberg, Cheryl L

    Journal of the American Geriatrics Society

    2021  Volume 69, Issue 11, Page(s) 3273–3284

    Abstract: Background: The Centers for Medicare & Medicaid Services (CMS) Home Health Quality Reporting Program (HHQRP) uses performance measurement to spur improvements in home health agencies' (HHAs') quality of care. We examined quality improvement (QI) ... ...

    Abstract Background: The Centers for Medicare & Medicaid Services (CMS) Home Health Quality Reporting Program (HHQRP) uses performance measurement to spur improvements in home health agencies' (HHAs') quality of care. We examined quality improvement (QI) activities HHAs reported making to improve on HHQRP quality measures, and whether reported QI activities were associated with better measure performance.
    Methods: We used responses (N = 1052) from a Web- and mail-based survey of a stratified random sample of HHAs included in CMS Home Health Compare in October 2019. We estimated national adoption rates for 27 possible QI activities related to organizational culture, health information technology, care process redesign, provider incentives, provider training, changes to staffing responsibilities, performance monitoring, and measure-specific QI initiatives and technical assistance. We used multivariate linear regression to examine the associations between HHA characteristics and QI adoption, and between QI adoption and CMS Home Health Quality of Patient Care Star Rating.
    Results: HHAs reported implementing an average of 16 QI activities (interquartile range 11-19 activities). Larger HHA size was associated with adopting 1.6 additional QI activities (p < 0.001). HHAs with higher proportions of disabled, black, or Hispanic patients adopted QI activities at similar or higher rates as other HHAs. Of the 27 QI activities, 23 were considered helpful by more than 80% of adopting HHAs. Compared with adopting 44% of QI activities (10th percentile among HHAs), adopting 89% of QI activities (90th percentile) was associated with a 0.4-star higher Star Rating (95% confidence interval 0.2-0.6).
    Conclusions: HHAs report implementing a significant number of QI activities in response to CMS measurement programs; implementation of a greater number of activities is associated with better performance on publicly reported measures. To guide future HHA QI investments, work is needed to identify the optimal combination of QI activities and the specific QI activities that yield the greatest performance improvements.
    MeSH term(s) Centers for Medicare and Medicaid Services, U.S. ; Home Care Agencies/organization & administration ; Home Care Agencies/standards ; Humans ; Medical Informatics ; Medicare/standards ; Motivation ; Organizational Culture ; Quality Improvement/standards ; Quality Indicators, Health Care/standards ; Surveys and Questionnaires ; United States
    Language English
    Publishing date 2021-08-06
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 80363-7
    ISSN 1532-5415 ; 0002-8614
    ISSN (online) 1532-5415
    ISSN 0002-8614
    DOI 10.1111/jgs.17368
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  9. Article: Design, modeling, and experimental validation of an acoustofluidic platform for nanoscale molecular synthesis and detection.

    Binkley, M M / Cui, M / Li, W / Tan, S / Berezin, M Y / Meacham, J M

    Physics of fluids (Woodbury, N.Y. : 1994)

    2019  Volume 31, Issue 8, Page(s) 82007

    Abstract: Microfluidic technologies are increasingly implemented to replace manual methods in biological and biochemical sample processing. We explore the feasibility of an acoustofluidic trap for confinement of microparticle reaction substrates against ... ...

    Abstract Microfluidic technologies are increasingly implemented to replace manual methods in biological and biochemical sample processing. We explore the feasibility of an acoustofluidic trap for confinement of microparticle reaction substrates against continuously flowing reagents in chemical synthesis and detection applications. Computational models are used to predict the flow and ultrasonic standing wave fields within two longitudinal standing bulk acoustic wave (LSBAW) microchannels operated in the 0.5-2.0 MHz range. Glass (gLSBAW) and silicon (siLSBAW) pillar arrays comprise trapping structures that augment the local acoustic field, while openings between pillars evenly distribute the flow for uniform exposure of substrates to reagents. Frequency spectra (acoustic energy density
    Language English
    Publishing date 2019-08-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1472743-2
    ISSN 1089-7666 ; 1070-6631
    ISSN (online) 1089-7666
    ISSN 1070-6631
    DOI 10.1063/1.5100149
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  10. Article ; Online: Radiotherapy for Brain Metastases from Thyroid Cancer: An Institutional and National Retrospective Cohort Study.

    Blomain, Erik / Berta, Scott / Hug, Nicholas / Giao, Duc / Meola, Antonio / Binkley, Michael / Hui, Caressa / Churilla, Thomas / Shahsavari, Nastaran / Desai, Kaniksha / Chang, Steven / Soltys, Scott / Pollom, Erqi

    Thyroid : official journal of the American Thyroid Association

    2022  Volume 32, Issue 7, Page(s) 781–788

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Brain Neoplasms/radiotherapy ; Brain Neoplasms/secondary ; Brain Neoplasms/surgery ; Cohort Studies ; Humans ; Necrosis/etiology ; Necrosis/surgery ; Radiation Injuries/etiology ; Radiosurgery/methods ; Retrospective Studies ; Thyroid Neoplasms/surgery ; Treatment Outcome
    Language English
    Publishing date 2022-06-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1086044-7
    ISSN 1557-9077 ; 1050-7256
    ISSN (online) 1557-9077
    ISSN 1050-7256
    DOI 10.1089/thy.2021.0628
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