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  1. Article ; Online: Novel Use of Intravascular Lithotripsy for Percutaneous Relief of Critical Right Ventricle-to-Pulmonary Artery Conduit Stenosis.

    Lee, Melissa G Y / Russo, Jeremy J / Norman, Samuel / Binny, Simon D / Joshi, Subodh B / Eastaugh, Lucas / Grigg, Leeanne E / Wilson, William M

    JACC. Cardiovascular interventions

    2023  Volume 16, Issue 21, Page(s) 2670–2672

    MeSH term(s) Humans ; Infant ; Heart Ventricles ; Pulmonary Artery/diagnostic imaging ; Constriction, Pathologic ; Treatment Outcome ; Transposition of Great Vessels ; Stenosis, Pulmonary Artery/diagnostic imaging ; Stenosis, Pulmonary Artery/etiology ; Stenosis, Pulmonary Artery/therapy ; Retrospective Studies ; Heart Defects, Congenital
    Language English
    Publishing date 2023-09-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2023.08.023
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    Zs.A 6669: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Use of abatacept in steroid refractory, immune checkpoint-induced myocarditis.

    Kalapurackal Mathai, Vinod / Black, Allison / Lovibond, Sam / Binny, Simon / Lipton, Jonathan / Moldovan, Cristina

    Internal medicine journal

    2021  Volume 51, Issue 11, Page(s) 1971–1972

    MeSH term(s) Abatacept ; Humans ; Myocarditis/chemically induced ; Myocarditis/drug therapy ; Nivolumab ; Steroids
    Chemical Substances Steroids ; Nivolumab (31YO63LBSN) ; Abatacept (7D0YB67S97)
    Language English
    Publishing date 2021-11-19
    Publishing country Australia
    Document type Letter
    ZDB-ID 2045436-3
    ISSN 1445-5994 ; 1444-0903
    ISSN (online) 1445-5994
    ISSN 1444-0903
    DOI 10.1111/imj.15566
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    Zs.A 792: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 424: Show issues

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  3. Article ; Online: Aortic root measurement on CT: linear dimensions, aortic root area and comparison with echocardiography. A retrospective cross sectional study.

    Leong, Kai'En / Knipe, Henry / Binny, Simon / Pascoe, Heather / Better, Nathan / Langenberg, Francesca / Lui, Elaine / Joshi, Subodh B

    The British journal of radiology

    2021  Volume 94, Issue 1121, Page(s) 20201232

    Abstract: Objective: We sought to assess the different CT aortic root measurements and determine their relationship to transthoracic echocardiography (TTE).: Methods: TTE and ECG-gated CT images were reviewed from 70 consecutive patients (mean age 54 ± 18 ... ...

    Abstract Objective: We sought to assess the different CT aortic root measurements and determine their relationship to transthoracic echocardiography (TTE).
    Methods: TTE and ECG-gated CT images were reviewed from 70 consecutive patients (mean age 54 ± 18 years; 67% male) with tricuspid aortic roots (trileaflet aortic valves) between Nov 2009 and Dec 2013. Three CT planes (coronal, short axis en face and three-chamber) were used for measurement of nine linear dimensions. TTE aortic root dimension was measured as per guidelines from the parasternal long axis view.
    Results: All CT short axis measurements of the aortic root had excellent reproducibility (intraclass correlation coefficient, ICC 0.96-0.99), while coronal and three-chamber planes had lower reproducibility with ICC 0.90 (95% CI 0.84-0.94) and ICC 0.92 (0.87-0.95) respectively. CT coronal and short axis maximal dimensions were systematically larger than TTE (mean 2 mm larger,
    Conclusion: Systematic differences exist between CT and TTE dependent on the CT plane of measurement. All CT short axis measurements of the aortic root had excellent reproducibility and correlation with aortic root area with maximal dimension appearing marginally better than the rest. Our findings highlight the importance of specifying the chosen plane of aortic root measurement on CT.
    Advances in knowledge: Systematic differences in aortic root dimension exist between TTE and the various CT measurement planes. CT coronal and short axis maximal dimensions were systematically larger than TTE, while CT cusp to commissure measurements were smaller. CT readers should indicate the plane of measurement and the specific linear dimension to avoid ambiguity in follow-up and comparison.
    MeSH term(s) Aorta/anatomy & histology ; Aorta/diagnostic imaging ; Aortic Valve/diagnostic imaging ; Contrast Media ; Cross-Sectional Studies ; Echocardiography/methods ; Female ; Humans ; Male ; Middle Aged ; Organ Size ; Reproducibility of Results ; Retrospective Studies ; Tomography, X-Ray Computed/methods
    Chemical Substances Contrast Media
    Language English
    Publishing date 2021-03-08
    Publishing country England
    Document type Comparative Study ; Journal Article
    ZDB-ID 2982-8
    ISSN 1748-880X ; 0007-1285
    ISSN (online) 1748-880X
    ISSN 0007-1285
    DOI 10.1259/bjr.20201232
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    Ue I Zs.11: Show issues Location:
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  4. Article: A rare case of a pericardial mass: Myelosarcoma from relapsed acute monoblastic leukaemia without bone marrow involvement.

    Binny, Simon / Tomlinson, Stephen / Hammett, Christopher / Dahiya, Arun / Pillai, Elango / Prasad, Sandhir B

    Australasian journal of ultrasound in medicine

    2017  Volume 20, Issue 4, Page(s) 178–180

    Abstract: Introduction: A 67-year-old male presented with progressive exertional dyspnoea, night sweats and 25 kg of weight loss over 2 years. He was febrile, 38.0°C, hypotensive and tachycardiac. Pulsus paradoxus was present. His electrocardiogram showed ... ...

    Abstract Introduction: A 67-year-old male presented with progressive exertional dyspnoea, night sweats and 25 kg of weight loss over 2 years. He was febrile, 38.0°C, hypotensive and tachycardiac. Pulsus paradoxus was present. His electrocardiogram showed electrical alternans. He had previously had acute myeloid leukaemia treated with three cycles of chemotherapy.
    Results: The patient was found to have a 3.6 cm pericardial effusion with features consistent with tamponade and three cardiac masses (largest 10 × 9 × 5 cm) and mediastinal lymphadenopathy. He had 825 mL of pericardial fluid drained from which cytology was consistent with extramedullary leukaemia. A bone marrow aspirate and trephine was normal.
    Conclusion: The findings suggested extramedullary recurrence of leukaemia in the pericardium, without bone marrow involvement.
    Language English
    Publishing date 2017-10-25
    Publishing country Australia
    Document type Case Reports
    ZDB-ID 2843953-3
    ISSN 2205-0140 ; 1836-6864
    ISSN (online) 2205-0140
    ISSN 1836-6864
    DOI 10.1002/ajum.12073
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  5. Article ; Online: Percutaneous Transvenous Mitral Valve-in-Valve Implantation Using Commercially Available Transcatheter Valve. First Australian Experience.

    Putrino, Anthony / Scalia, Gregory / Natani, Sarvesh / Margale, Swaroop / Rapchuk, Ivan / Binny, Simon / Lau, Catherine / Lwin, Myo / Clarke, Andrew / Raffel, Christopher / Walters, Darren L

    Heart, lung & circulation

    2018  Volume 27, Issue 4, Page(s) e42–e45

    Abstract: In patients with a degenerative mitral bioprosthesis and prohibitive surgical risk there is emerging evidence for the feasibility of valve-in-valve procedures via a percutaneous transvenous transseptal approach. This paper describes the first time this ... ...

    Abstract In patients with a degenerative mitral bioprosthesis and prohibitive surgical risk there is emerging evidence for the feasibility of valve-in-valve procedures via a percutaneous transvenous transseptal approach. This paper describes the first time this procedure has been performed in Australia.
    MeSH term(s) Aged, 80 and over ; Animals ; Bioprosthesis/adverse effects ; Cardiac Catheterization/methods ; Cattle ; Echocardiography, Transesophageal ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation/methods ; Humans ; Male ; Mitral Valve/physiopathology ; Mitral Valve/surgery ; Mitral Valve Insufficiency/diagnosis ; Mitral Valve Insufficiency/surgery ; Prosthesis Failure ; Queensland ; Reoperation
    Language English
    Publishing date 2018-04
    Publishing country Australia
    Document type Case Reports ; Journal Article
    ZDB-ID 2020980-0
    ISSN 1444-2892 ; 1443-9506
    ISSN (online) 1444-2892
    ISSN 1443-9506
    DOI 10.1016/j.hlc.2017.11.002
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4988: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Modified Precordial Lead R-Wave Deflection Interval Predicts Left- and Right-Sided Idiopathic Outflow Tract Ventricular Arrhythmias.

    Anderson, Robert D / Kumar, Saurabh / Binny, Simon / Prabhu, Mukund / Al-Kaisey, Ahmed / Parameswaran, Ramanathan / Sugumar, Hariharan / Chieng, David / Hawson, Joshua / Campbell, Timothy / Joshi, Subodh / Lui, Elaine / Sparks, Paul B / Joseph, Stephen A / Morton, Joseph B / McLellan, Alex / Lipton, Jonathan / Pathik, Bhupesh / Kistler, Peter M /
    Kalman, Jonathan / Lee, Geoffrey

    JACC. Clinical electrophysiology

    2020  Volume 6, Issue 11, Page(s) 1405–1419

    Abstract: Objectives: This study evaluated if modifying electrocardiographic (ECG) precordial leads to a higher intercostal position improved the accuracy of outflow tract ventricular arrhythmia (OTVA) localization.: Background: Precordial ECG prediction ... ...

    Abstract Objectives: This study evaluated if modifying electrocardiographic (ECG) precordial leads to a higher intercostal position improved the accuracy of outflow tract ventricular arrhythmia (OTVA) localization.
    Background: Precordial ECG prediction algorithms that use a standard lead configuration localize OTVA with variable accuracy.
    Methods: Patients who underwent OTVA ablation were prospectively enrolled to have a standard and modified (high) precordial ECG. R- and S-wave amplitudes and intervals were measured to develop an algorithm that differentiated the right ventricular outflow tract (RVOT) and the left ventricular outflow tract (LVOT) with high accuracy-the modified lead R-wave deflection interval (RWDI). This interval was defined from the earliest QRS onset (using all modified leads) to the lead with longest R-wave deflection. The RWDI was compared with all other ECG algorithms.
    Results: A total of 50 patients (38 women; mean age 51 ± 17 years) had successful catheter ablation for OTVA (RVOT 60%, LVOT 40%). The modified lead RWDI was significantly shorter in the RVOT group (18.5 ms, interquartile range 25th to 75th percentile [IQR
    Conclusions: The modified lead RWDI is a simple, easily interpretable algorithm that can potentially differentiate a right- or left-sided origin of OTVA with high accuracy.
    MeSH term(s) Arrhythmias, Cardiac/diagnosis ; Catheter Ablation ; Electrocardiography ; Female ; Heart Ventricles/diagnostic imaging ; Heart Ventricles/surgery ; Humans ; Middle Aged ; Tachycardia, Ventricular/diagnosis ; Tachycardia, Ventricular/surgery
    Language English
    Publishing date 2020-09-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2846739-5
    ISSN 2405-5018 ; 2405-500X ; 2405-500X
    ISSN (online) 2405-5018 ; 2405-500X
    ISSN 2405-500X
    DOI 10.1016/j.jacep.2020.07.011
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  7. Article ; Online: Epicardial Adipose Tissue Accumulation Confers Atrial Conduction Abnormality.

    Nalliah, Chrishan J / Bell, James R / Raaijmakers, Antonia J A / Waddell, Helen M / Wells, Simon P / Bernasochi, Gabriel B / Montgomery, Magdalene K / Binny, Simon / Watts, Troy / Joshi, Subodh B / Lui, Elaine / Sim, Choon Boon / Larobina, Marco / O'Keefe, Michael / Goldblatt, John / Royse, Alistair / Lee, Geoffrey / Porrello, Enzo R / Watt, Matthew J /
    Kistler, Peter M / Sanders, Prashanthan / Delbridge, Lea M D / Kalman, Jonathan M

    Journal of the American College of Cardiology

    2020  Volume 76, Issue 10, Page(s) 1197–1211

    Abstract: Background: Clinical studies have reported that epicardial adipose tissue (EpAT) accumulation associates with the progression of atrial fibrillation (AF) pathology and adversely affects AF management. The role of local cardiac EpAT deposition in disease ...

    Abstract Background: Clinical studies have reported that epicardial adipose tissue (EpAT) accumulation associates with the progression of atrial fibrillation (AF) pathology and adversely affects AF management. The role of local cardiac EpAT deposition in disease progression is unclear, and the electrophysiological, cellular, and molecular mechanisms involved remain poorly defined.
    Objectives: The purpose of this study was to identify the underlying mechanisms by which EpAT influences the atrial substrate for AF.
    Methods: Patients without AF undergoing coronary artery bypass surgery were recruited. Computed tomography and high-density epicardial electrophysiological mapping of the anterior right atrium were utilized to quantify EpAT volumes and to assess association with the electrophysiological substrate in situ. Excised right atrial appendages were analyzed histologically to characterize EpAT infiltration, fibrosis, and gap junction localization. Co-culture experiments were used to evaluate the paracrine effects of EpAT on cardiomyocyte electrophysiology. Proteomic analyses were applied to identify molecular mediators of cellular electrophysiological disturbance.
    Results: Higher local EpAT volume clinically correlated with slowed conduction, greater electrogram fractionation, increased fibrosis, and lateralization of cardiomyocyte connexin-40. In addition, atrial conduction heterogeneity was increased with more extensive myocardial EpAT infiltration. Cardiomyocyte culture studies using multielectrode arrays showed that cardiac adipose tissue-secreted factors slowed conduction velocity and contained proteins with capacity to disrupt intermyocyte electromechanical integrity.
    Conclusions: These findings indicate that atrial pathophysiology is critically dependent on local EpAT accumulation and infiltration. In addition to myocardial architecture disruption, this effect can be attributed to an EpAT-cardiomyocyte paracrine axis. The focal adhesion group proteins are identified as new disease candidates potentially contributing to arrhythmogenic atrial substrate.
    MeSH term(s) Adipose Tissue/diagnostic imaging ; Adipose Tissue/physiopathology ; Aged ; Animals ; Atrial Fibrillation/diagnostic imaging ; Atrial Fibrillation/physiopathology ; Cells, Cultured ; Coculture Techniques ; Epicardial Mapping/methods ; Female ; Heart Conduction System/diagnostic imaging ; Heart Conduction System/physiopathology ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Middle Aged ; Pericardium/diagnostic imaging ; Pericardium/physiopathology ; Proteomics/methods
    Language English
    Publishing date 2020-09-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2020.07.017
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    Zs.A 1846: Show issues Location:
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    Zs.MO 196: Show issues

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