LIVIVO - Search results -

Search results

Result 1 - 10 of total 42

Search options

Article: Opposite effects of IFN-gamma on CCR5 and CXCR4 expression and on entry of M- and T-tropic HIV in epithelial cells.

Biolchini, A / Curreli, S / Ziccheddu, M / Serra, C / Dolei, A

2000 Volume 14, Issue 5, Page(s) 613–615

MeSH term(s)	Antiviral Agents/pharmacology ; Cell Line ; Epithelial Cells/drug effects ; Epithelial Cells/virology ; HIV-1/physiology ; HeLa Cells ; Humans ; Interferon-gamma/pharmacology ; Receptors, CCR5/metabolism ; Receptors, CXCR4/metabolism
Chemical Substances	Antiviral Agents ; Receptors, CCR5 ; Receptors, CXCR4 ; Interferon-gamma (82115-62-6)
Language	English
Publishing date	2000-03-31
Publishing country	England
Document type	Letter ; Research Support, Non-U.S. Gov't
ZDB-ID	639076-6
ISSN	1473-5571 ; 0269-9370 ; 1350-2840
ISSN (online)	1473-5571
ISSN	0269-9370 ; 1350-2840
DOI	10.1097/00002030-200003310-00016
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2228: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Type III and I interferons increase HIV uptake and replication in human cells that overexpress CD4, CCR5, and CXCR4.

Serra, Caterina / Biolchini, Adriana / Mei, Alessandra / Kotenko, Sergei / Dolei, Antonina

AIDS research and human retroviruses

2008 Volume 24, Issue 2, Page(s) 173–180

Abstract: The newly discovered type III interferon lambda (IFN-lambda) has antiviral activity against a broad spectrum of viruses and potent immune-related activities. Its major producers are peripheral blood mononuclear cells (PBMCs) and dendritic cells. The ... ...

Abstract	The newly discovered type III interferon lambda (IFN-lambda) has antiviral activity against a broad spectrum of viruses and potent immune-related activities. Its major producers are peripheral blood mononuclear cells (PBMCs) and dendritic cells. The above functions and cells are deeply involved in AIDS pathogenesis, but there is no information so far on IFN-lambda effects on HIV. Therefore we addressed the sensitivity of HIV-1 replication to cell exposure to human IFN-lambda2. Human PBMCs and C8166 T cells were treated with human Type III or Type I IFNs, and the ability of HIV-1 to bind and replicate in untreated and IFN-treated cells was investigated. Virus amounts were quantified by infectivity and p24 assays. In parallel, we evaluated the possible antiproliferative effects of IFN-lambda2 and the expression of CD4, CXCR4, and CCR5 genes, whose transcripts were quantified by real time RT-PCR. Data showed increased adsorption of HIV to IFN-treated cells in a dose-dependent fashion. Virus yields increased accordingly. In both systems the accumulation of CD4, CXCR4, and CCR5 transcripts was increased, particularly in PBMCs. Antiproliferative activity and classical antiviral state were instead detected on PBMCs, but not on C8166 cells. We concluded that pretreatment of PBMCs and C8166 cells with Type III and Type I IFNs causes increased HIV binding and replication. These effects are likely to be due to increased expression of HIV receptors and coreceptors on the plasma membrane. These findings indicate another mechanism utilized by HIV for subversion of host defenses.
MeSH term(s)	CD4 Antigens/biosynthesis ; CD4 Antigens/genetics ; Cell Line ; Cells, Cultured ; Cytokines/immunology ; Gene Expression Profiling ; HIV Core Protein p24/biosynthesis ; HIV-1/growth & development ; HIV-1/immunology ; Humans ; Interferon Type I/immunology ; Interleukins/immunology ; Leukocytes, Mononuclear/virology ; Receptors, CCR5/biosynthesis ; Receptors, CCR5/genetics ; Receptors, CXCR4/biosynthesis ; Receptors, CXCR4/genetics ; T-Lymphocytes/virology ; Virus Internalization ; Virus Replication
Chemical Substances	CD4 Antigens ; CXCR4 protein, human ; Cytokines ; HIV Core Protein p24 ; interferon-lambda, human ; Interferon Type I ; Interleukins ; Receptors, CCR5 ; Receptors, CXCR4
Language	English
Publishing date	2008-01-31
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	639130-8
ISSN	1931-8405 ; 0889-2229
ISSN (online)	1931-8405
ISSN	0889-2229
DOI	10.1089/aid.2007.0198
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1928: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article: Pidotimod in the prophylaxis of recurrent acute tonsillitis in childhood.

Careddu, P / Biolchini, A / Alfano, S / Zavattini, G

Advances in oto-rhino-laryngology

1992 Volume 47, Page(s) 328–331

MeSH term(s)	Acute Disease ; Adolescent ; Child ; Child, Preschool ; Double-Blind Method ; Female ; Humans ; Male ; Pyrrolidonecarboxylic Acid/analogs & derivatives ; Pyrrolidonecarboxylic Acid/therapeutic use ; Recurrence ; Thiazoles/therapeutic use ; Thiazolidines ; Tonsillitis/prevention & control
Chemical Substances	Thiazoles ; Thiazolidines ; pidotimod (785363R681) ; Pyrrolidonecarboxylic Acid (SZB83O1W42)
Language	English
Publishing date	1992
Publishing country	Switzerland
Document type	Clinical Trial ; Journal Article ; Randomized Controlled Trial
ISSN	0065-3071
ISSN	0065-3071
DOI	10.1159/000421766
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

Article: Prevenzione con immunoterapia locale delle infezioni respiratorie ricorrenti nel bambino.

Venturi, M C / Biolchini, A / Bardare, M

Minerva pediatrica

1991 Volume 43, Issue 9, Page(s) 557–561

Abstract: A group of 20 children aged between 2.5 and 10 years with recurrent respiratory infections (greater than 6/year) was treated with local immunotherapy (Biomunil spray) for a six-month period (October-March 1988/89). Referring to the same period on last ... ...

Title translation	Local immunotherapy prevention of recurrent respiratory infections in children.
Abstract	A group of 20 children aged between 2.5 and 10 years with recurrent respiratory infections (greater than 6/year) was treated with local immunotherapy (Biomunil spray) for a six-month period (October-March 1988/89). Referring to the same period on last year, a statistically significant decrease of upper respiratory infections was observed (p less than 0.001) as well as an increase of S-IgA rate (p less than 0.001) and less of serum IgA and IgG. The compliance and the tolerance of the drug was good.
MeSH term(s)	Adjuvants, Immunologic/administration & dosage ; Adjuvants, Immunologic/adverse effects ; Administration, Intranasal ; Biological Factors/administration & dosage ; Biological Factors/adverse effects ; Child ; Child, Preschool ; Drug Evaluation ; Drug Tolerance ; Female ; Humans ; Immunotherapy/methods ; Male ; Recurrence ; Respiratory Tract Infections/prevention & control ; Ribosomes/immunology
Chemical Substances	Adjuvants, Immunologic ; Biological Factors
Language	Italian
Publishing date	1991-09
Publishing country	Italy
Document type	English Abstract ; Journal Article
ZDB-ID	123571-0
ISSN	1827-1715 ; 0026-4946
ISSN (online)	1827-1715
ISSN	0026-4946
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Um IV Zs.161: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Immunologic investigations in eight patients with incontinentia pigmenti.

Menni, S / Piccinno, R / Biolchini, A / Plebani, A

Pediatric dermatology

1990 Volume 7, Issue 4, Page(s) 275–277

Abstract: We studied eight patients with incontinentia pigmenti to investigate the possibility of immunologic abnormalities. In six patients a defect of polymorphonuclear chemotaxis was revealed; lymphocyte subpopulations, serum immunoglobulin levels, and ... ...

Abstract	We studied eight patients with incontinentia pigmenti to investigate the possibility of immunologic abnormalities. In six patients a defect of polymorphonuclear chemotaxis was revealed; lymphocyte subpopulations, serum immunoglobulin levels, and peripheral eosinophils were within normal limits. We hope these findings will stimulate further investigations into the mechanisms involved.
MeSH term(s)	Adolescent ; Chemotaxis, Leukocyte ; Child ; Child, Preschool ; Female ; Granulocytes ; Humans ; Immunoglobulins/analysis ; Incontinentia Pigmenti/immunology ; Incontinentia Pigmenti/pathology ; Lymphocyte Subsets ; Male
Chemical Substances	Immunoglobulins
Language	English
Publishing date	1990-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	605539-4
ISSN	1525-1470 ; 0736-8046
ISSN (online)	1525-1470
ISSN	0736-8046
DOI	10.1111/j.1525-1470.1990.tb01024.x
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1882: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Acropustulose infantile associée à une dermatite atopique, des infections cutanées récidivantes et une hyper-IgE.

Menni, S / Piccinno, R / Biolchini, A

Annales de dermatologie et de venereologie

1988 Volume 115, Issue 1, Page(s) 33–35

Title translation	Infantile acropustulosis associated with atopic dermatitis, recurrent cutaneous infections and hyper-immunoglobulinemia E.
MeSH term(s)	Eosinophils/analysis ; Humans ; Hypergammaglobulinemia/complications ; Hypersensitivity, Immediate/complications ; Immunoglobulin E ; Infant ; Leukocyte Count ; Male ; Recurrence ; Skin Diseases, Infectious/complications ; Skin Diseases, Vesiculobullous/complications
Chemical Substances	Immunoglobulin E (37341-29-0)
Language	French
Publishing date	1988
Publishing country	France
Document type	Case Reports ; Journal Article
ZDB-ID	391805-1
ISSN	2214-5451 ; 0151-9638
ISSN (online)	2214-5451
ISSN	0151-9638
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ui VI Zs.30: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Increased replication of T-cell-tropic HIV strains and CXC-chemokine receptor-4 induction in T cells treated with macrophage inflammatory protein (MIP)-1alpha, MIP-1beta and RANTES beta-chemokines.

Dolei, A / Biolchini, A / Serra, C / Curreli, S / Gomes, E / Dianzani, F

AIDS (London, England)

1998 Volume 12, Issue 2, Page(s) 183–190

Abstract: Objective and design: To study, in T-lymphoid cells, the effects of macrophage inflammatory protein (MIP)-1alpha, MIP-1beta and RANTES beta-chemokines on the replication of T-cell-tropic HIV-1 strains, since it has been reported that beta-chemokines ... ...

Abstract	Objective and design: To study, in T-lymphoid cells, the effects of macrophage inflammatory protein (MIP)-1alpha, MIP-1beta and RANTES beta-chemokines on the replication of T-cell-tropic HIV-1 strains, since it has been reported that beta-chemokines interfere with the replication of macrophage-tropic HIV-1 strains, but not T-cell-tropic strains. Methods: Freshly phytohaemagglutinin (PHA)-activated peripheral blood lymphocytes (PBL) and cultured PHA-activated T cells from healthy volunteers, as well as the C8166 T-cell line, were treated overnight with beta-chemokines before infection with T-cell-tropic HIV-1 isolates, or human T-lymphotropic virus type IIIB. HIV replication was followed by detecting the production of infectious particles, p24 antigen, and viral sequences. CXC-chemokine receptor (CXCR)-4 expression was followed by detection and quantification of specific transcripts. Results: Pretreatment of T cells with MIP-1alpha, MIP-1beta and RANTES affected T-cell-tropic strains, increased the replication of HIV-1beta and HIV-1RPdT strains dose-dependently, as well as virus absorption and provirus DNA accumulation. These findings were associated with increased accumulation of CXCR-4 transcripts, and mediated by the protein tyrosine kinase signalling. Moreover, beta-chemokines stimulated PBL proliferation. Conclusions: Beta-chemokines increase the adsorption and replication of at least some T-cell-tropic HIV-1 strains, and this is related to stimulated expression of the CXCR-4 coreceptor.
MeSH term(s)	Cell Division ; Cell Line ; Cells, Cultured ; Chemokine CCL3 ; Chemokine CCL4 ; Chemokine CCL5/pharmacology ; Chemotaxis, Leukocyte ; DNA, Viral/blood ; Deltaretrovirus/immunology ; Deltaretrovirus/physiology ; HIV-1/immunology ; HIV-1/physiology ; Humans ; Lymphocyte Activation ; Macrophage Inflammatory Proteins/pharmacology ; Polymerase Chain Reaction ; Protein-Tyrosine Kinases/metabolism ; Proviruses/isolation & purification ; RNA-Directed DNA Polymerase ; Receptors, CXCR4/biosynthesis ; Receptors, CXCR4/genetics ; Signal Transduction ; T-Lymphocytes/cytology ; T-Lymphocytes/immunology ; T-Lymphocytes/virology ; Virus Replication
Chemical Substances	Chemokine CCL3 ; Chemokine CCL4 ; Chemokine CCL5 ; DNA, Viral ; Macrophage Inflammatory Proteins ; Receptors, CXCR4 ; Protein-Tyrosine Kinases (EC 2.7.10.1) ; RNA-Directed DNA Polymerase (EC 2.7.7.49)
Language	English
Publishing date	1998-01-22
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	639076-6
ISSN	1473-5571 ; 0269-9370 ; 1350-2840
ISSN (online)	1473-5571
ISSN	0269-9370 ; 1350-2840
DOI	10.1097/00002030-199802000-00008
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2228: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Characterization of an HIV type 1 strain with preferential replication in adherent cells.

Serra, Caterina / Mameli, Giuseppe / Biolchini, Adriana / Ziccheddu, Maria / Curreli, Sabrina / Arru, Giannina / Dolei, Antonina

AIDS research and human retroviruses

2002 Volume 18, Issue 9, Page(s) 641–647

Abstract: HIV-E, emerging from persistently infected HeLa-T4 cells, replicates better in fibroblasts and epithelial cells with respect to the parental, T cell-derived HIV-T. The two viruses share the same env V3 loop, but differ in cellular molecules incorporated ... ...

Abstract	HIV-E, emerging from persistently infected HeLa-T4 cells, replicates better in fibroblasts and epithelial cells with respect to the parental, T cell-derived HIV-T. The two viruses share the same env V3 loop, but differ in cellular molecules incorporated on the envelope. Even when similar amounts of virus attachment occurred, HIV-E replicated better than HIV-T in cells from solid tissues, and the response to exogenous Tat was more efficient. This might be related to the long terminal repeat (LTR), because HIV-E has a TAR duplication, and a mutation in the Sp1-II binding site. Epithelial cells deserve further study, because they may be important in vivo for variant selection and latency.
MeSH term(s)	Base Sequence ; Epithelial Cells/virology ; Fibroblasts/virology ; Gene Products, tat/physiology ; HIV Long Terminal Repeat/physiology ; HIV-1/classification ; HIV-1/physiology ; HeLa Cells ; Humans ; Molecular Sequence Data ; Mutation ; RNA, Viral/analysis ; Virus Replication/physiology ; tat Gene Products, Human Immunodeficiency Virus
Chemical Substances	Gene Products, tat ; RNA, Viral ; tat Gene Products, Human Immunodeficiency Virus
Language	English
Publishing date	2002-06-10
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	639130-8
ISSN	1931-8405 ; 0889-2229
ISSN (online)	1931-8405
ISSN	0889-2229
DOI	10.1089/088922202760019338
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1928: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Prenatal immune status of fetuses of HIV-seropositive mothers.

Plebani, A / Biolchini, A / Bucceri, A / Buscaglia, M / Pardi, G / Semprini, A E

Gynecologic and obstetric investigation

1990 Volume 29, Issue 2, Page(s) 108–111

Abstract: Human immunodeficiency virus (HIV) has been isolated from fetal tissues as early as 13 weeks and later from fetal blood. These findings have raised the possibility of prenatal diagnosis of infected fetuses by identification of the virus in the fetal ... ...

Abstract	Human immunodeficiency virus (HIV) has been isolated from fetal tissues as early as 13 weeks and later from fetal blood. These findings have raised the possibility of prenatal diagnosis of infected fetuses by identification of the virus in the fetal compartment. Study of the fetal immune status has proved reliable in prenatal diagnosis of congenital immunodeficiency, and we have tested the possibility to diagnose acquired immunodeficiency in utero by this approach. We studied T lymphocyte subsets and their mitogenic response in fetal blood obtained after elective termination at midgestation in 8 cases and at delivery in 26 cases of maternal HIV infection. Results have been compared to appropriate normal controls. No significant difference was found in terms of total lymphocytes, CD4 and CD8 populations and phytohemagglutinin responses. This indicates either that immunological parameters currently used to assess postnatal immunodeficiency are not reliable during intrauterine life or that the intrauterine environment and the transplacental passage of maternal antibodies interfere with development of prenatal immunodeficiency.
MeSH term(s)	AIDS Serodiagnosis ; Acquired Immunodeficiency Syndrome/diagnosis ; Acquired Immunodeficiency Syndrome/immunology ; Cell Count ; Female ; Fetal Diseases/diagnosis ; Fetus/immunology ; Humans ; Lymphocytes/analysis ; Maternal-Fetal Exchange ; Pregnancy ; Prenatal Diagnosis
Language	English
Publishing date	1990
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	800003-7
ISSN	1423-002X ; 0378-7346
ISSN (online)	1423-002X
ISSN	0378-7346
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 688: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Incontinentia pigmenti and Behçet's syndrome: an unusual combination.

Menni, S / Piccinno, R / Biolchini, A / Delle Piane, R M / Bardare, M

Acta dermato-venereologica

1986 Volume 66, Issue 4, Page(s) 351–354

Abstract: We describe an unusual case of a child who had had incontinentia pigmenti from birth and developed the clinical picture of Behçet's syndrome at five years of age. Among the various investigations performed, chemotactic activity of the polymorphonuclear ... ...

Abstract	We describe an unusual case of a child who had had incontinentia pigmenti from birth and developed the clinical picture of Behçet's syndrome at five years of age. Among the various investigations performed, chemotactic activity of the polymorphonuclear leukocyte was found to be low. We discuss the possibility that there are common immunological abnormalities in the two syndromes.
MeSH term(s)	Behcet Syndrome/complications ; Behcet Syndrome/diagnosis ; Behcet Syndrome/immunology ; Chemotaxis, Leukocyte ; Child, Preschool ; Female ; Humans ; Incontinentia Pigmenti/complications ; Incontinentia Pigmenti/immunology ; Neutrophils ; Pigmentation Disorders/complications
Language	English
Publishing date	1986
Publishing country	Sweden
Document type	Case Reports ; Journal Article
ZDB-ID	80007-7
ISSN	1651-2057 ; 0001-5555
ISSN (online)	1651-2057
ISSN	0001-5555
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ui VI Zs.101: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito