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  1. Article: Association of Helicobacter pylori in Children With Self-Hand Hygiene, Maternal Hand Hygiene, Cooking, and Feeding Practices.

    Thorat, Janhavi V / Tambolkar, Sampada / Chitale, Mukta M / Biradar, Vishnu / Jadhav, Renuka S

    Cureus

    2024  Volume 16, Issue 3, Page(s) e56554

    Abstract: Background and ... ...

    Abstract Background and objective
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.56554
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Reply to Dr. Chung and colleagues.

    Dashatwar, Parag / Biradar, Vishnu / Bapaye, Amol

    Endoscopy

    2022  Volume 54, Issue 5, Page(s) 526

    Language English
    Publishing date 2022-04-21
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-1782-7656
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Reply to Dr. Chung and colleagues

    Dashatwar, Parag / Biradar, Vishnu / Bapaye, Amol

    Endoscopy

    2022  Volume 54, Issue 05, Page(s) 526–526

    Language English
    Publishing date 2022-04-21
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-1782-7656
    Database Thieme publisher's database

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  4. Article ; Online: Initial experience with per-rectal endoscopic myotomy for Hirschsprung's disease: medium and long term outcomes of the first case series of a novel third-space endoscopy procedure.

    Bapaye, Amol / Dashatwar, Parag / Biradar, Vishnu / Biradar, Shital / Pujari, Rajendra

    Endoscopy

    2021  Volume 53, Issue 12, Page(s) 1256–1260

    Abstract: Introduction: Hirschsprung's disease (HSCR) is congenital aganglionosis affecting the hindgut and presents with constipation. Surgical pull-through is the current standard treatment but causes morbidity. Per-rectal endoscopic myotomy is a novel third- ... ...

    Abstract Introduction: Hirschsprung's disease (HSCR) is congenital aganglionosis affecting the hindgut and presents with constipation. Surgical pull-through is the current standard treatment but causes morbidity. Per-rectal endoscopic myotomy is a novel third-space endoscopy technique for treating short-segment (SS)-HSCR.
    Methods: Retrospective study of SS-HSCR patients diagnosed on history, contrast enema, rectal biopsies, and anorectal manometry, and treated by PREM. The aganglionic segment was mapped before PREM was performed using third-space endoscopy principles. Stool frequency and laxative usage before and after PREM were compared.
    Results: Nine patients (age 7.5 [± 5.2] years; 7 male) underwent PREM during a 4-year period. Mean aganglionic segment length was 6.3 cm, mean procedure time 96.1 minutes, and mean length of hospital stay 2.5 days. Median follow-up was 17 months (range 9-58 months). Stool frequency was 1/4.4 days before vs. 1/1.2 days after PREM (
    Conclusions: PREM is a safe and effective minimally invasive procedure to treat SS-HSCR and results in long-term response.
    MeSH term(s) Child ; Digestive System Surgical Procedures ; Endoscopy ; Hirschsprung Disease/surgery ; Humans ; Male ; Myotomy ; Retrospective Studies
    Language English
    Publishing date 2021-03-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-1332-6902
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Current practices in the management of corrosive ingestion in children: A questionnaire-based survey and recommendations.

    Bolia, Rishi / Sarma, Moinak Sen / Biradar, Vishnu / Sathiyasekaran, Malathi / Srivastava, Anshu

    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology

    2021  Volume 40, Issue 3, Page(s) 316–325

    Abstract: Background and aim: Corrosive ingestion causes significant morbidity in children with no standard guidelines regarding management. This survey aimed to understand practices adopted by gastroenterologists, identify lacunae in evaluation and management ... ...

    Abstract Background and aim: Corrosive ingestion causes significant morbidity in children with no standard guidelines regarding management. This survey aimed to understand practices adopted by gastroenterologists, identify lacunae in evaluation and management and suggest a practical algorithm.
    Methods: Indian gastroenterologists participated in an online survey (65 questions) on managing corrosive ingestion. When ≥ 50% of respondents agreed on a management option, it was considered as 'agreement'.
    Results: Ninety-eight gastroenterologists (72 pediatric) who had managed a total of ~ 2600 corrosive ingestions in the last 5 years responded. The commonest age group affected was 2-5 years (61%). Majority of ingestion was accidental (89%) with 80% due to improper corrosive storage. Ingestion of alkali and acid was equally common (alkali 41%, acid 39%, unknown 20%). History of inducing-vomiting after ingestion by community physicians was present in 57%. There was an agreement on 77% of questions. The respondents agreed on endoscopy (70%) and chest X-ray (67%) in all, irrespective of symptoms. Endoscopy was considered safe on days 1-5 after ingestion (91%) and relatively contraindicated thereafter. The consensus was to use acid suppression, always (59%); steroids, never (68%) and antibiotics, if indicated (59%). Feeding was based on endoscopic findings: oral in mild injuries and nasogastric (NG) in others. Eighty percent placed a NG tube under endoscopic guidance. Stricture dilatation was considered safe after 4 weeks of ingestion. Agreement on duration of acid suppression and stricture management (dilatation protocol and refractory strictures) was lacking.
    Conclusion: Corrosive ingestion mostly affects 2-5-year olds and is accidental in majority. It can be potentially prevented by proper storage and labelling of corrosives. An algorithm for management is proposed.
    MeSH term(s) Burns, Chemical/etiology ; Burns, Chemical/therapy ; Caustics/toxicity ; Child ; Child, Preschool ; Eating ; Endoscopy, Gastrointestinal ; Esophageal Stenosis/chemically induced ; Esophageal Stenosis/therapy ; Humans ; Surveys and Questionnaires
    Chemical Substances Caustics
    Language English
    Publishing date 2021-05-15
    Publishing country India
    Document type Journal Article
    ZDB-ID 632595-6
    ISSN 0975-0711 ; 0254-8860
    ISSN (online) 0975-0711
    ISSN 0254-8860
    DOI 10.1007/s12664-021-01153-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Initial experience with per-rectal endoscopic myotomy for Hirschsprung’s disease: medium and long term outcomes of the first case series of a novel third-space endoscopy procedure

    Bapaye, Amol / Dashatwar, Parag / Biradar, Vishnu / Biradar, Shital / Pujari, Rajendra

    Endoscopy

    2020  Volume 53, Issue 12, Page(s) 1256–1260

    Abstract: Introduction : Hirschsprung’s disease (HSCR) is congenital aganglionosis affecting the hindgut and presents with constipation. Surgical pull-through is the current standard treatment but causes morbidity. Per-rectal endoscopic myotomy is a novel third- ... ...

    Abstract Introduction : Hirschsprung’s disease (HSCR) is congenital aganglionosis affecting the hindgut and presents with constipation. Surgical pull-through is the current standard treatment but causes morbidity. Per-rectal endoscopic myotomy is a novel third-space endoscopy technique for treating short-segment (SS)-HSCR.
    Methods : Retrospective study of SS-HSCR patients diagnosed on history, contrast enema, rectal biopsies, and anorectal manometry, and treated by PREM. The aganglionic segment was mapped before PREM was performed using third-space endoscopy principles. Stool frequency and laxative usage before and after PREM were compared.
    Results : Nine patients (age 7.5 [± 5.2] years; 7 male) underwent PREM during a 4-year period. Mean aganglionic segment length was 6.3 cm, mean procedure time 96.1 minutes, and mean length of hospital stay 2.5 days. Median follow-up was 17 months (range 9–58 months). Stool frequency was 1/4.4 days before vs. 1/1.2 days after PREM ( P  = 0.0004). Mean laxative usage was 5.4 units of laxative (UL) before vs. 0.4 UL after PREM ( P  = 0.0002). No laxatives were used by 6/9 patients after PREM. The single adverse effect seen (anal stenosis) was treated with dilatation.
    Conclusions : PREM is a safe and effective minimally invasive procedure to treat SS-HSCR and results in long-term response.
    Language English
    Publishing date 2020-12-08
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-1332-6902
    Database Thieme publisher's database

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  7. Article ; Online: Low Osmolarity Oral Rehydration Salt Solution (LORS) in Management of Dehydration in Children.

    Mohanty, Nimain / Thapa, Babu Ram / Mathai, John / Pai, Uday / Mohanty, Niranjan / Biradar, Vishnu / Jog, Pramod / Prabhu, Purnima

    Indian pediatrics

    2021  Volume 58, Issue 3, Page(s) 266–272

    Abstract: Justification: The IAP last published the guidelines "Comprehensive Management of Diarrhea" in 2006 and a review in 2016. The WHO in 2002 and the Government of India in 2004 recommended low osmolarity rehydration solution (LORS) as the universal ... ...

    Abstract Justification: The IAP last published the guidelines "Comprehensive Management of Diarrhea" in 2006 and a review in 2016. The WHO in 2002 and the Government of India in 2004 recommended low osmolarity rehydration solution (LORS) as the universal rehydration solution for all ages and all forms of dehydration. However, the use of LORS in India continues to be unacceptably low at 51%, although awareness about ORS has increased from a mere 14% in 2005 to 69% in 2015. Availability of different compositions of ORS and brands in market added to the confusion.
    Process: The Indian Academy of Pediatrics constituted a panel of experts from the fields of pediatrics, pediatric gastroenterology and nutrition to update on management of dehydration in children with particular reference to LORS and issue a current practice guideline. The committee met twice at CIAP HQ to review all published literature on the aspect. Brief presentations were made, followed by discussions. The draft paper was circulated by email. All relevant inputs and suggestions were incorporated to arrive at a consensus on this practice guideline.
    Objectives: To summarize latest literature on ORT and empower pediatricians, particularly those practicing in rural areas, on management of dehydration by augmenting LORS use.
    Recommendations: It was stressed that advantages of LORS far out-weigh its limitations. Increased use of LORS can only be achieved by promoting better awareness among public and health-care providers across all systems of medicine. LORS can also be useful in managing dehydration in non-diarrheal illness. More research is required to modify ORS further to make it safe and effective in neonates, severe acute malnutrition, renal failure, cardiac and other co-morbidities. There is an urgent need to discourage production and marketing all forms of ORS not in conformity with WHO approved LORS, under a slogan "One India, one ORS".
    MeSH term(s) Child ; Dehydration/therapy ; Diarrhea/therapy ; Fluid Therapy ; Humans ; Infant ; Infant, Newborn ; Osmolar Concentration ; Rehydration Solutions/therapeutic use
    Chemical Substances Rehydration Solutions
    Language English
    Publishing date 2021-03-13
    Publishing country India
    Document type Journal Article
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
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  8. Article ; Online: Pediatric living donor intestine transplant following an atypical complication of COVID-19: A unique case report from India.

    Chaubal, Gaurav / Hatimi, Hunaid / Nanavati, Aditya / Deshpande, Apoorv / Andankar, Parmanand / Biradar, Vishnu / Gupte, Parijat / Hanchnale, Pavan / Bhalerao, Suryabhan / Tambe, Shrinivas

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

    2021  Volume 21, Issue 12, Page(s) 4079–4083

    Abstract: Coronavirus disease-19 (COVID-19) infection causing severe gastrointestinal complications is rare. A 9-year-old child after recovering from mild COVID-19 infection developed small bowel gangrene due to superior mesenteric artery thrombosis. He required ... ...

    Abstract Coronavirus disease-19 (COVID-19) infection causing severe gastrointestinal complications is rare. A 9-year-old child after recovering from mild COVID-19 infection developed small bowel gangrene due to superior mesenteric artery thrombosis. He required resection of entire necrotic small bowel along with caecum causing ultra-short bowel syndrome. Reverse transcriptase-polymerase chain reaction (RT-PCR) done on the resected specimen was positive for COVID-19. He was maintained on individualized parenteral nutrition for 3 months. A living donor intestinal transplant was performed using 200 cm of ileum donated by the patient's father. The graft function was satisfactory and was not complicated with thrombosis, infection, reactivation of latent COVID-19 or rejection. He could be weaned off completely from parenteral nutrition by postoperative day 21. The donor had an uneventful recovery. Six month follow-up was satisfactory with the child achieving complete enteral autonomy as well as target goal nutrition. Thrombotic phenomena associated with COVID-19 infection can affect larger vessel-like superior mesenteric artery leading to small bowel gangrene. Intestine transplant could be done safely after 3 months of recovery from COVID-19 without any adverse outcomes. Further studies are required to establish optimal timing and safety of small bowel transplant in this situation.
    MeSH term(s) COVID-19 ; Child ; Humans ; Intestines/surgery ; Living Donors ; Male ; SARS-CoV-2 ; Short Bowel Syndrome/etiology ; Short Bowel Syndrome/surgery ; Treatment Outcome
    Language English
    Publishing date 2021-09-09
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2060594-8
    ISSN 1600-6143 ; 1600-6135
    ISSN (online) 1600-6143
    ISSN 1600-6135
    DOI 10.1111/ajt.16798
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  9. Article ; Online: Monosegment Liver Allografts for Liver Transplantation in Infants Weighing Less Than 6 kg: An Initial Indian Experience.

    Chaubal, Gaurav / Nanavati, Aditya J / Biradar, Vishnu / Tambe, Shrinivas / Hatimi, Hunaid / Deshpande, Apurv / Hanchnale, Pavan / Bhalerao, Suryabhan

    Transplantation proceedings

    2021  Volume 53, Issue 5, Page(s) 1670–1673

    Abstract: Background: Living donor liver transplantation in small infants is a significant challenge. Liver allografts from adults may be large in size. This is accompanied by problems of graft perfusion, dysfunction, and the inability to achieve primary closure ... ...

    Abstract Background: Living donor liver transplantation in small infants is a significant challenge. Liver allografts from adults may be large in size. This is accompanied by problems of graft perfusion, dysfunction, and the inability to achieve primary closure of the abdomen. Monosegment grafts are a way to address these issues.
    Methods: Two recipients in our cohort weighed less then 6 kg. The prospective left lateral segments from their donors were large for size. Therefore, monosegment 2 liver grafts were harvested. Data regarding the preoperative, intraoperative, and postoperative events in the donor and the recipient were recorded.
    Results: We were able to achieve significant reduction in the sizes of the grafts harvested. The donors underwent surgery and hospital stay uneventfully. The recipients had normal graft perfusion and no graft dysfunction, and we could achieve primary abdominal closure. One recipient had self-limiting bile leak postoperatively.
    Conclusions: Monosegment 2 liver allografts are safe and effective for use in living donor liver transplantation in small infants weighing less than 6 kg.
    MeSH term(s) Adult ; Allografts ; Body Weight ; Female ; Humans ; India ; Infant ; Length of Stay ; Liver/anatomy & histology ; Liver/surgery ; Liver Transplantation ; Living Donors ; Male ; Middle Aged ; Prospective Studies
    Language English
    Publishing date 2021-02-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82046-5
    ISSN 1873-2623 ; 0041-1345
    ISSN (online) 1873-2623
    ISSN 0041-1345
    DOI 10.1016/j.transproceed.2021.01.005
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  10. Article ; Online: Therapeutic coil embolization of dominant shunt in hepatopulmonary syndrome enhances post-liver transplant respiratory recovery.

    Sonavane, Amey D / Bagde, Abhijit / Raut, Vikram / Marar, Shaji / Sawant, Ambreen / Shah, Ketul / Raj, Amruth / Thorat, Ashok / Chaksota, Harshit / Biradar, Vishnu / Vasanth, Suresh / Nagral, Aabha / Mirza, Darius

    Pediatric transplantation

    2020  Volume 24, Issue 6, Page(s) e13729

    Abstract: Coil embolization of the atypical enlarged pulmonary artery/arteriole with visible shunting may improve hypoxemia in patients with hepatopulmonary syndrome (HPS). When used selectively in cases with large shunts, either pre- or post-liver transplantation ...

    Abstract Coil embolization of the atypical enlarged pulmonary artery/arteriole with visible shunting may improve hypoxemia in patients with hepatopulmonary syndrome (HPS). When used selectively in cases with large shunts, either pre- or post-liver transplantation (LT), it can aid an early recovery and reduce morbidity. We present a case where a large intrapulmonary shunt was embolized preoperatively to improve hypoxemia associated with HPS and enhance post-operative recovery.
    MeSH term(s) Arterioles/surgery ; Ascites ; Child, Preschool ; Embolization, Therapeutic/methods ; End Stage Liver Disease/surgery ; Hepatopulmonary Syndrome/surgery ; Humans ; Hypertension, Portal ; Hypoxia/metabolism ; Hypoxia/surgery ; Liver Cirrhosis/physiopathology ; Liver Transplantation/methods ; Male ; Methylenetetrahydrofolate Reductase (NADPH2)/genetics ; Mutation ; Postoperative Period ; Pulmonary Artery/surgery ; Tomography, X-Ray Computed ; Treatment Outcome
    Chemical Substances MTHFR protein, human (EC 1.5.1.20) ; Methylenetetrahydrofolate Reductase (NADPH2) (EC 1.5.1.20)
    Language English
    Publishing date 2020-05-21
    Publishing country Denmark
    Document type Case Reports
    ZDB-ID 1390284-2
    ISSN 1399-3046 ; 1397-3142
    ISSN (online) 1399-3046
    ISSN 1397-3142
    DOI 10.1111/petr.13729
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