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Article ; Online: Enjeux et mise en œuvre de radiothérapie postopératoire après chirurgie reconstructrice avec lambeau dans les cancers de la tête et du cou.

Blache, Alice / Carsuzaa, Florent / Beddok, Arnaud / Deneuve, Sophie / Marcy, Pierre-Yves / James, Dylan / Dejean, Catherine / Dapké, Stéphanie / Devauchelle, Bernard / Thariat, Juliette

Bulletin du cancer

2024  Volume 111, Issue 5, Page(s) 496–504

Abstract: The management of head and neck cancers is multidisciplinary, often relying on the use of combined treatments to maximize the chances of cure. Combined treatments are however also responsible for cumulative side effects. The aim of reconstructive surgery ...

Title translation Issues and implementation of postoperative radiotherapy after flap reconstructive surgery in head and neck cancers.
Abstract The management of head and neck cancers is multidisciplinary, often relying on the use of combined treatments to maximize the chances of cure. Combined treatments are however also responsible for cumulative side effects. The aim of reconstructive surgery with a flap is to restore a function lost with the loss of substance from the tumor resection. However, changes in reconstructive surgery have impact of postoperative radiotherapy planning. The optimization of imaging protocols for radiotherapy planning should make it possible to identify postoperative changes and to distinguish flaps from surrounding native tissues to delineate the flaps and document the spontaneous evolution of these flaps or dose-effect relationships in case of radiotherapy. Such changes include atrophy, fibrosis of soft tissue flaps and osteoradionecrosis of bone flaps. Radiotherapy optimization also involves standardization of the definition of target volumes in situations where a flap is present, a situation that is increasingly common in routine care. This evolution of practice, beyond the essential multidisciplinary consultation meetings defining treatment indications, requires a close radio surgical collaboration with respect to technical aspects of the two disciplines. Doing so, anticipation of relapse and toxicity profiles could possibly lead to propose strategies for personalized de-escalation of multimodal treatments through interdisciplinary trials.
MeSH term(s) Humans ; Head and Neck Neoplasms/radiotherapy ; Head and Neck Neoplasms/surgery ; Plastic Surgery Procedures/methods ; Surgical Flaps ; Osteoradionecrosis/etiology ; Osteoradionecrosis/surgery ; Postoperative Care/methods ; Fibrosis ; Radiotherapy, Adjuvant/adverse effects ; Radiotherapy, Adjuvant/methods ; Radiotherapy Planning, Computer-Assisted/methods
Language French
Publishing date 2024-03-28
Publishing country France
Document type English Abstract ; Journal Article ; Review
ZDB-ID 213270-9
ISSN 1769-6917 ; 0007-4551
ISSN (online) 1769-6917
ISSN 0007-4551
DOI 10.1016/j.bulcan.2024.02.002
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