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  1. Article: Collagenous Gastritis: A Cause of Pediatric Iron Deficiency Anemia.

    Blackmore, Conner / Leach, Margaret

    ACG case reports journal

    2023  Volume 10, Issue 2, Page(s) e01000

    Abstract: Collagenous gastritis (CG) is a rare histopathological condition characterized by subepithelial collagen deposition and inflammatory infiltrates in the gastric mucosa. With less than 100 cases reported in current literature, clinical presentation is ... ...

    Abstract Collagenous gastritis (CG) is a rare histopathological condition characterized by subepithelial collagen deposition and inflammatory infiltrates in the gastric mucosa. With less than 100 cases reported in current literature, clinical presentation is highly variable. We report a case of isolated CG in an 11-year-old girl who presented with a 6-month history of symptomatic severe iron deficiency anemia (nonexertional shortness of breath, palpitations, chest pain, and lethargy). CG is a rare condition in children require long-term follow-up and monitoring of their disease; and because of its rarity, a targeted treatment does not exist. The current therapeutic strategy is focused on symptom control and monitoring iron studies, in conjunction with regular follow-up.
    Language English
    Publishing date 2023-03-04
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.0000000000001000
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Endoscopic Management of Bouveret Syndrome With Electrohydraulic Lithotripsy.

    Wang, Hunter / Blackmore, Conner / Bonnichsen, Mark / Ermerak, George / Bassan, Milan

    ACG case reports journal

    2023  Volume 10, Issue 5, Page(s) e01051

    Language English
    Publishing date 2023-05-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.0000000000001051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Temporal change in aetiology and clinical characteristics of hepatocellular carcinoma in a large cohort of patients in New South Wales, Australia.

    Yeoh, Yuen Kang Joseph / Dore, Gregory J / Lockart, Ian / Danta, Mark / Flynn, Ciara / Blackmore, Conner / Levy, Miriam T / George, Jacob / Alavi, Maryam / Hajarizadeh, Behzad

    Internal medicine journal

    2023  Volume 54, Issue 4, Page(s) 602–612

    Abstract: Background: Viral hepatitis, alcohol-related liver disease (ARLD) and nonalcoholic fatty liver disease (NAFLD) are the main risk factors for hepatocellular carcinoma (HCC) in many countries. In Australia, given the access to hepatitis C virus (HCV) ... ...

    Abstract Background: Viral hepatitis, alcohol-related liver disease (ARLD) and nonalcoholic fatty liver disease (NAFLD) are the main risk factors for hepatocellular carcinoma (HCC) in many countries. In Australia, given the access to hepatitis C virus (HCV) direct-acting antiviral (DAA) therapy since 2016, a temporal change in HCC aetiology was hypothesized. This study evaluated the temporal change in the aetiology and characteristics of HCC in New South Wales (NSW).
    Methods: Patients diagnosed with HCC, admitted to three public hospitals in NSW between 2008 and 2021, were included in the analyses. We assessed the annual frequency of each HCC aetiology and the distribution of HCC characteristics in participants.
    Results: Among 1370 patients, the most common HCC etiologies were HCV (n = 483, 35%), ARLD (n = 452, 33%), NAFLD (n = 347, 25%) and hepatitis B virus (n = 301, 22%). The proportion of HCV-related HCC was the highest in 2011-2016 (41%) and significantly declined to 30% in 2017-2021 (odds ratio [OR], 0.53 [95% confidence interval (CI), 0.35-0.79]; P = 0.002). The proportion of HCC diagnosed at an early stage (Barcelona Clinic Liver Cancer stage O/A) increased from 41% in 2008-2009 to 56% in 2020-2021 (OR per annum, 1.05 [95% CI, 1.02-1.08]; P = 0.002), and the proportion of patients receiving potentially curative HCC management increased from 29% in 2008-2009 to 41% in 2020-2021 (OR per annum, 1.06 [95% CI, 1.03-1.10]; P < 0.001).
    Conclusion: The contribution of HCV to HCC burden has been decreasing in the DAA era, suggesting the role of HCV elimination in decreasing HCC risk. Increasing frequency of less advanced HCC at diagnosis over time suggests improved HCC surveillance.
    MeSH term(s) Humans ; Carcinoma, Hepatocellular/diagnosis ; Carcinoma, Hepatocellular/epidemiology ; Carcinoma, Hepatocellular/etiology ; Liver Neoplasms/epidemiology ; Antiviral Agents/therapeutic use ; New South Wales/epidemiology ; Non-alcoholic Fatty Liver Disease/diagnosis ; Non-alcoholic Fatty Liver Disease/epidemiology ; Non-alcoholic Fatty Liver Disease/therapy ; Hepatitis C, Chronic/complications ; Hepatitis C, Chronic/drug therapy ; Hepatitis C, Chronic/epidemiology ; Hepatitis C/complications ; Hepatitis C/epidemiology ; Australia ; Hepacivirus
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2023-10-11
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2045436-3
    ISSN 1445-5994 ; 1444-0903
    ISSN (online) 1445-5994
    ISSN 1444-0903
    DOI 10.1111/imj.16252
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Sensitivity of Video-Based Pulse Arrival Time to Dynamic Blood Pressure Changes.

    Shirbani, Fatemeh / Blackmore, Conner / Kazzi, Christina / Tan, Isabella / Butlin, Mark / Avolio, Alberto P

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

    2018  Volume 2018, Page(s) 3639–3641

    Abstract: Estimating blood pressure (BP) from pulse arrival time (PAT) by image-based (skin video) photoplethysmography (iPPG) is of increasing interest due to the non-contact method advantage (over cuff-based methods) and potential for BP measurement to be built ... ...

    Abstract Estimating blood pressure (BP) from pulse arrival time (PAT) by image-based (skin video) photoplethysmography (iPPG) is of increasing interest due to the non-contact method advantage (over cuff-based methods) and potential for BP measurement to be built into portable devices such as mobile phones. The relationship between pulse transit time extracted from iPPG has been investigated during stable BP. The sensitivity of beat-to-beat iPPG-PAT to dynamic changes in BP has not been explored. This study investigated the correlation between iPPG-PAT and diastolic BP (DBP) during 1-minute seated rest and 3-minute isometric handgrip exercise. 15 healthy participants (9 female, 34±13 years) were recruited. Video was recorded from subjects' faces at 30 frames per second using a standard web-camera with simultaneous measurement of the electrocardiogram and noninvasive finger BP. The iPPG waveform was from the averaged green channel intensity of regions of the forehead or cheek. PAT was calculated from the R-wave ofthe electrocardiogram to the foot of the iPPG or finger BP waveform respectively for direct comparison. Handgrip exercise caused a steady increase in DBP (75±9 to 87±13 mmHg, p<0.001). Beat-to-beat iPPG-PAT and DBP was negatively correlated (mena ±SE -1.33±1.70 ms/mmHg, P=0.0024) as was finger-PAT (mean ±SE -0.5S ±0.39 ms/mmHg, P<0.001). The proportion of individual significant negative regression slopes between DBP and finger-PAT and between DBP and iPPG-PAT was not significantly different. Despite high variability of the correlation between iPPG-PAT and DBP among subjects, iPPG-PAT can track dynamic changes in BP.
    MeSH term(s) Adult ; Blood Pressure ; Blood Pressure Determination ; Female ; Hand Strength ; Heart Rate ; Humans ; Male ; Middle Aged ; Photoplethysmography ; Pulse Wave Analysis ; Young Adult
    Language English
    Publishing date 2018-09-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2694-0604
    ISSN (online) 2694-0604
    DOI 10.1109/EMBC.2018.8513058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Effects of instructed meditation augmented by computer-rendered artificial virtual environment on heart rate variability.

    Kazzi, Christina / Blackmore, Conner / Shirbani, Fatemeh / Tan, Isabella / Butlin, Mark / Avolio, Alberto P / Barin, Edward

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

    2018  Volume 2018, Page(s) 2768–2771

    Abstract: Previous research has supported the use of virtual reality (VR) to decrease stress, anxiety, perceptions of pain, and increase positive affect. However, the effect of VR on blood pressure (BP) and autonomic function in healthy populations have not been ... ...

    Abstract Previous research has supported the use of virtual reality (VR) to decrease stress, anxiety, perceptions of pain, and increase positive affect. However, the effect of VR on blood pressure (BP) and autonomic function in healthy populations have not been explored. This study quantifies the effect of instructed meditation augmented by a virtual environment (VE) on BP and heart rate variability (HRV) during rest and following physical (isometric handgrip) or mental (serial sevens subtraction) stress. Sixteen healthy participants underwent all conditions, and those that responded to the stress tests were included in the analysis of stress recovery. Results showed that under resting conditions, VE had no significant effect on BP or HRV when compared to seated rest and the VE video on a 2D screen. Following serial sevens, VE maintained the increased low frequency (LF) power of HRV $( 66 \pm 4$ normalized units (n.u.)) compared to seated rest $( 55 \pm 5\mathrm {n}$.u., $\mathrm {p}=0.0060)$; VE maintained the decreased high frequency (HF) power of HRV $( 34 \pm 4\mathrm {n}$.u.) compared to seated rest $( 44 \pm 5\mathrm {n}$.u., $\mathrm {p}=0.014)$; and VE maintained the increased LF/HF ratio $( 2.4 \pm 0.5)$ compared to seated rest $( 1.6 \pm 0.3$, $\mathrm {p}=0.012)$. Hence, after mental stress, VE sustains the increased sympathetic drive and reduced parasympathetic drive. VE may act as a stimulatory driver for autonomic activity and BP. Further studies are required to investigate the effect of different types of VE on BP and autonomic function.
    MeSH term(s) Adult ; Aged ; Autonomic Nervous System/physiology ; Blood Pressure ; Female ; Hand Strength ; Heart Rate ; Humans ; Male ; Meditation/methods ; Middle Aged ; Software/standards ; Virtual Reality
    Language English
    Publishing date 2018-09-17
    Publishing country United States
    Document type Journal Article
    ISSN 2694-0604
    ISSN (online) 2694-0604
    DOI 10.1109/EMBC.2018.8512816
    Database MEDical Literature Analysis and Retrieval System OnLINE

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