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  1. Article ; Online: Fibroepithelial polyp of the ureter: a prolapsing ureteric mass.

    Buckland, Benjamin Charles / Blatt, Alison

    ANZ journal of surgery

    2022  Volume 93, Issue 4, Page(s) 1031–1032

    MeSH term(s) Humans ; Ureter/diagnostic imaging ; Ureter/surgery ; Ureter/pathology ; Ureteral Neoplasms/diagnosis ; Ureteral Neoplasms/surgery ; Ureteroscopy ; Polyps/diagnosis ; Polyps/surgery ; Polyps/pathology ; Prolapse
    Language English
    Publishing date 2022-09-19
    Publishing country Australia
    Document type Case Reports
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.18057
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    Zs.A 180: Show issues Location:
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  2. Article ; Online: We have cracked the ceiling, but how long must we walk on broken glass? Addressing the pitfalls confronting women in surgery.

    Lockhart, Kathleen Rebecca / Blatt, Alison

    ANZ journal of surgery

    2021  Volume 91, Issue 9, Page(s) 1647–1649

    MeSH term(s) Female ; General Surgery ; Humans ; Physicians, Women
    Language English
    Publishing date 2021-09-10
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.17072
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  3. Article ; Online: Female urethral disruption in low-velocity blunt trauma: a case report.

    Storey, Benjamin / Shugg, Nathan / Thirugnanasundralingam, Vaisnavi / Blatt, Alison

    ANZ journal of surgery

    2020  Volume 90, Issue 9, Page(s) 1809–1810

    MeSH term(s) Female ; Humans ; Male ; Urethra/diagnostic imaging ; Urethra/surgery ; Wounds, Nonpenetrating/diagnosis ; Wounds, Nonpenetrating/diagnostic imaging
    Language English
    Publishing date 2020-01-14
    Publishing country Australia
    Document type Case Reports ; Journal Article
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.15703
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  4. Article ; Online: Does the introduction of pre-operative cardiopulmonary exercise testing in radical cystectomy delay or alter surgical care?

    Lockhart, Kathleen R / Carroll, Rosemary / Tiu, Albert / Blatt, Alison

    BJUI compass

    2021  Volume 3, Issue 3, Page(s) 238–242

    Abstract: Objectives: To assess if the introduction of routine pre-operative cardiopulmonary exercise testing (CPET) in radical cystectomy has delayed surgical intervention.: Materials and methods: A prospective database of patients undergoing radical ... ...

    Abstract Objectives: To assess if the introduction of routine pre-operative cardiopulmonary exercise testing (CPET) in radical cystectomy has delayed surgical intervention.
    Materials and methods: A prospective database of patients undergoing radical cystectomy in our local health network was maintained. A retrospective analysis of two years (2018-2020) included 38 patients. Of these, 15 patients had CPET pre-operatively, and a direct comparison was performed.
    Results: The mean time from diagnosis to cystectomy was 95 days in patients who did not have CPET compared to 110 days for those who did (
    Conclusion: CPET is a valuable risk evaluation tool. This study suggested that CPET contributed to a minor non-significant delay to surgery, however was associated with reduced length of stay and readmission rates, and was a valuable risk evaluation tool. We found that CPET AT <11 ml/kg/min is associated with higher rates of patient morbidity and perioperative mortality.
    Language English
    Publishing date 2021-12-12
    Publishing country United States
    Document type Journal Article
    ISSN 2688-4526
    ISSN (online) 2688-4526
    DOI 10.1002/bco2.133
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  5. Article ; Online: Tumour innervation and neurosignalling in prostate cancer.

    March, Brayden / Faulkner, Sam / Jobling, Phillip / Steigler, Allison / Blatt, Alison / Denham, Jim / Hondermarck, Hubert

    Nature reviews. Urology

    2020  Volume 17, Issue 2, Page(s) 119–130

    Abstract: Prostate cancer progression has been shown to be dependent on the development of autonomic nerves into the tumour microenvironment. Sympathetic nerves activate adrenergic neurosignalling that is necessary in early stages of tumour progression and for ... ...

    Abstract Prostate cancer progression has been shown to be dependent on the development of autonomic nerves into the tumour microenvironment. Sympathetic nerves activate adrenergic neurosignalling that is necessary in early stages of tumour progression and for initiating an angiogenic switch, whereas parasympathetic nerves activate cholinergic neurosignalling resulting in tumour dissemination and metastasis. The innervation of prostate cancer seems to be initiated by neurotrophic growth factors, such as the precursor to nerve growth factor secreted by tumour cells, and the contribution of brain-derived neural progenitor cells has also been reported. Current experimental, epidemiological and clinical evidence shows the stimulatory effect of tumour innervation and neurosignalling in prostate cancer. Using nerves and neurosignalling could have value in the management of prostate cancer by predicting aggressive disease, treating localized disease through denervation and relieving cancer-associated pain in bone metastases.
    MeSH term(s) Denervation ; Humans ; Male ; Prognosis ; Prostate/innervation ; Prostatic Neoplasms/diagnosis ; Prostatic Neoplasms/pathology ; Prostatic Neoplasms/therapy ; Signal Transduction ; Tumor Microenvironment
    Language English
    Publishing date 2020-01-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2493737-X
    ISSN 1759-4820 ; 1759-4812
    ISSN (online) 1759-4820
    ISSN 1759-4812
    DOI 10.1038/s41585-019-0274-3
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    Zs.A 6030: Show issues Location:
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  6. Article ; Online: Transurethral prostate resection in patients with hypocontractile detrusor--what is the predictive value of ultrastructural detrusor changes?

    Blatt, Alison H / Brammah, Susan / Tse, Vincent / Chan, Lewis

    The Journal of urology

    2012  Volume 188, Issue 6, Page(s) 2294–2299

    Abstract: Purpose: Men with detrusor failure and chronic urinary retention have a lower voiding success rate and higher postoperative morbidity following transurethral prostatectomy than those with bladder outlet obstruction. Current investigations, including ... ...

    Abstract Purpose: Men with detrusor failure and chronic urinary retention have a lower voiding success rate and higher postoperative morbidity following transurethral prostatectomy than those with bladder outlet obstruction. Current investigations, including urodynamics, may be unable to predict the response to surgical treatment. We identified ultrastructural features on detrusor biopsy that correlated with the postoperative voiding outcome in patients with a hypocontractile detrusor undergoing transurethral prostatectomy.
    Materials and methods: Detrusor biopsies were obtained from 17 patients with urodynamic evidence of bladder outlet obstruction or a hypocontractile detrusor undergoing transurethral prostatectomy and from 5 controls. Specimens were examined by transmission electron microscopy. Ten individual detrusor ultrastructural features were analyzed. Findings were compared with preoperative and postoperative clinical parameters.
    Results: Failure to void after transurethral prostatectomy was significantly associated with the ultrastructural features of variation in muscle cell size, muscle cell shape, collagenosis and abnormal fascicles. These 4 features were significantly associated with each other, defining a distinctive pattern of detrusor failure. For transurethral prostatectomy failure the sensitivity, specificity, and positive and negative predictive values of all 4 features together were 60%, 91%, 75% and 84%, respectively. Three or 4 features on detrusor biopsy predicted voiding failure.
    Conclusions: Detrusor ultrastructural analysis is highly predictive of voiding outcome following transurethral prostatectomy in patients with detrusor failure. Patients with ultrastructural features previously described as part of the myohypertrophy pattern do not have a primary diagnosis of bladder outlet obstruction but rather detrusor failure secondary to bladder outlet obstruction.
    MeSH term(s) Aged ; Aged, 80 and over ; Humans ; Male ; Middle Aged ; Muscle, Smooth/ultrastructure ; Predictive Value of Tests ; Transurethral Resection of Prostate ; Urinary Bladder/ultrastructure
    Language English
    Publishing date 2012-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1016/j.juro.2012.08.010
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  7. Article: Day-only laparoscopic cholecystectomy in a regional teaching hospital.

    Blatt, Alison / Chen, Stanley

    ANZ journal of surgery

    2003  Volume 73, Issue 5, Page(s) 321–325

    Abstract: Background: Day-only laparoscopic cholecystectomy (DOLC) has been demonstrated to be a safe and feasible procedure. The aim of the present study was to introduce DOLC to a busy teaching hospital without a separate day-surgery facility, to identify any ... ...

    Abstract Background: Day-only laparoscopic cholecystectomy (DOLC) has been demonstrated to be a safe and feasible procedure. The aim of the present study was to introduce DOLC to a busy teaching hospital without a separate day-surgery facility, to identify any problems associated with early discharge, and to determine patient satisfaction.
    Methods: Over a 2-year period, all patients undergoing elective laparoscopic cholecystectomy under one surgeon were prospectively studied. Patients satisfying criteria for DOLC were offered the procedure. All patients were sent anonymous satisfaction surveys postoperatively.
    Results: One hundred and one patients underwent elective laparoscopic cholecystectomies and 41 of these patients were booked for DOLC. Thirty-three (80%) were successfully discharged the same day and there were no complications related to early discharge. Only two of eight unplanned admissions were because of postoperative pain or nausea. Thirty-two (78%) of DOLC patients replied to our survey and of those, 24 (78%) were satisfied with their length of stay. The extra strain placed on day-stay ward resources was reflected in patient survey comments on their care.
    Conclusions: Our findings support the evidence that DOLC is safe and feasible. However, in a busy teaching hospital with tight budget constraints and no separate day-surgery facility we found many patients satisfied with their length of stay but not always with the quality of care they received on the day-stay ward. The latter was insufficiently equipped to handle procedures of this complexity. So although in theory DOLC has many advantages, we are unable to institute this as routine practice at this time.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Ambulatory Surgical Procedures/adverse effects ; Cholecystectomy, Laparoscopic/adverse effects ; Female ; Gallbladder Diseases/surgery ; Hospitals, Teaching ; Humans ; Male ; Middle Aged ; Outcome Assessment (Health Care) ; Patient Satisfaction ; Postoperative Complications ; Prospective Studies
    Language English
    Publishing date 2003-04-08
    Publishing country Australia
    Document type Evaluation Studies ; Journal Article
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1046/j.1445-2197.2003.t01-1-02614.x
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    Zs.A 180: Show issues Location:
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  8. Article ; Online: Ultrasound measurement of bladder wall thickness in the assessment of voiding dysfunction.

    Blatt, Alison H / Titus, Jehan / Chan, Lewis

    The Journal of urology

    2008  Volume 179, Issue 6, Page(s) 2275–8; discussion 2278–9

    Abstract: Purpose: Ultrasound measurement of bladder wall thickness has been proposed as a useful diagnostic parameter in patients with bladder outlet obstruction and other voiding dysfunctions. We assessed bladder wall thickness measurement as a noninvasive test ...

    Abstract Purpose: Ultrasound measurement of bladder wall thickness has been proposed as a useful diagnostic parameter in patients with bladder outlet obstruction and other voiding dysfunctions. We assessed bladder wall thickness measurement as a noninvasive test in patients with suspected bladder outlet obstruction or overactive bladder syndrome.
    Materials and methods: Transabdominal ultrasound measurement of bladder wall thickness was performed during urodynamic study in 180 patients with nonneurogenic voiding dysfunction. Two measurements of anterior bladder wall thickness, 1 cm apart in the midline and averaged, were obtained at 200 ml filling. Bladder wall thickness findings were correlated with urodynamic diagnoses.
    Results: A total of 180 patients with an average age of 62 years (range 20 to 94) were recruited, comprising 73 males and 107 females. Of the patients 69 had normal urodynamics, 39 had bladder outlet obstruction, 38 had increased bladder sensation on cystometry and 34 had detrusor overactivity. Bladder wall thickness was 1.1 to 4.5 mm in all groups. Males had a slightly thicker bladder wall than females (mean 2.1 vs 1.9 mm, p = 0.064). Mean bladder wall thickness in patients with normal urodynamics, bladder outlet obstruction, detrusor overactivity and increased bladder sensation was 2.0, 2.1, 1.9 and 1.8 mm, respectively. No significant difference was found between the groups (ANOVA p = 0.064, not significant). In particular there was no difference in bladder wall thickness between patients with normal urodynamics, and those with bladder outlet obstruction (p = 0.31) or detrusor overactivity (p = 0.309).
    Conclusions: Bladder wall thickness is remarkably uniform in patients with nonneurogenic voiding dysfunction. Therefore, it cannot reliably predict bladder outlet obstruction or detrusor overactivity. Bladder wall thickness measurement does not provide an alternative to urodynamic studies for diagnosing voiding dysfunction.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Ultrasonography ; Urinary Bladder/diagnostic imaging ; Urinary Bladder/pathology ; Urinary Bladder Neck Obstruction/diagnostic imaging ; Urinary Bladder Neck Obstruction/pathology ; Urinary Bladder, Overactive/diagnostic imaging ; Urinary Bladder, Overactive/pathology
    Language English
    Publishing date 2008-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1016/j.juro.2008.01.118
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