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  1. Book ; Online: New Insights in the Landscape of Rare Tumors: Translational and Clinical Research Perspective

    Ibrahim, Toni / Blay, Jean-Yves / Bongiovanni, Alberto / De Vita, Alessandro

    2020  

    Keywords Medicine ; Oncology ; rare tumors ; bone and soft tissue sarcoma ; neuroendocrine neoplasms and endocrine gland tumors ; central nervous system neoplasms ; cholangiocarcinoma ; von Hippel-Lindau disease
    Size 1 electronic resource (166 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021231314
    ISBN 9782889662579 ; 2889662578
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: EORTC - 50 years of progress against cancer

    Blay, Jean-Yves

    (1962 - 2012)

    (EJC Supplements ; 10,1)

    2012  

    Institution European Organization for Research on Treatment of Cancer
    Author's details guest ed. J.-Y. Blay
    Series title EJC Supplements ; 10,1
    European journal of cancer
    Collection European journal of cancer
    Language English
    Size VIII, 166 S. : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT017205166
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Editorial: precision medicine of sarcomas and aggressive connective tissue tumours: from one-size-fits-all to haute couture.

    Blay, Jean-Yves

    Current opinion in oncology

    2022  Volume 34, Issue 4, Page(s) 320–321

    MeSH term(s) Humans ; Neoplasms, Connective Tissue ; Precision Medicine ; Sarcoma/therapy ; Soft Tissue Neoplasms/genetics ; Soft Tissue Neoplasms/therapy
    Language English
    Publishing date 2022-07-14
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 1049384-0
    ISSN 1531-703X ; 1040-8746
    ISSN (online) 1531-703X
    ISSN 1040-8746
    DOI 10.1097/CCO.0000000000000849
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Keeping the balance, the true major goal in advanced sarcoma.

    Blay, Jean-Yves

    Future oncology (London, England)

    2021  Volume 17, Issue 21s, Page(s) 11–16

    Abstract: Achieving a balance between long-term efficacy and good quality of life (QoL) is the main goal of treatment for patients with advanced soft tissue sarcoma, some of whom experience prolonged survival without progression. An awareness of the challenges ... ...

    Abstract Achieving a balance between long-term efficacy and good quality of life (QoL) is the main goal of treatment for patients with advanced soft tissue sarcoma, some of whom experience prolonged survival without progression. An awareness of the challenges particular to this complex set of diseases can help preserve patient QoL during treatment. Histology is among the main factors to consider when selecting treatment in advanced disease. Close attention to the toxicity profiles of available regimens is of particular importance, especially in more advanced lines where the population is usually more vulnerable. Surgical outcomes are significantly better in patients managed with expert care, and early referral to sarcoma reference centers is key to improving survival and QoL.
    MeSH term(s) Aged ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/adverse effects ; Clinical Decision-Making ; Fatigue/chemically induced ; Fatigue/diagnosis ; Female ; Goals ; Humans ; Male ; Middle Aged ; Neoadjuvant Therapy/adverse effects ; Neoadjuvant Therapy/methods ; Neoplasm Staging ; Progression-Free Survival ; Quality of Life ; Risk Assessment ; Sarcoma/diagnosis ; Sarcoma/pathology ; Sarcoma/therapy ; Severity of Illness Index ; Surgical Procedures, Operative ; Time-to-Treatment ; Treatment Outcome
    Chemical Substances Antineoplastic Agents
    Language English
    Publishing date 2021-06-10
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2274956-1
    ISSN 1744-8301 ; 1479-6694
    ISSN (online) 1744-8301
    ISSN 1479-6694
    DOI 10.2217/fon-2021-0451
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Sarcoma management: expertise and balance.

    Blay, Jean-Yves

    Future oncology (London, England)

    2021  Volume 17, Issue 21s, Page(s) 1

    MeSH term(s) Humans ; Sarcoma/therapy
    Language English
    Publishing date 2021-06-10
    Publishing country England
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 2274956-1
    ISSN 1744-8301 ; 1479-6694
    ISSN (online) 1744-8301
    ISSN 1479-6694
    DOI 10.2217/fon-2021-0448
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: The evolution of a revolutionary class

    Blay, Jean-Yves / Demetri, George D.

    extending the benefits of tyrosine kinase inhibitors

    (Seminars in oncology ; 38,2, Suppl. 1)

    2011  

    Author's details Jean-Yves Blay and George D. Demetri, guest eds
    Series title Seminars in oncology ; 38,2, Suppl. 1
    Collection
    Language English
    Size S33 S. : graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia, Pa
    Publishing country United States
    Document type Book
    HBZ-ID HT016785558
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: Foreword.

    Blay, Jean-Yves

    Expert review of anticancer therapy

    2020  Volume 20, Issue sup1, Page(s) 1–2

    MeSH term(s) Humans ; Sarcoma/pathology ; Sarcoma/therapy
    Language English
    Publishing date 2020-04-29
    Publishing country England
    Document type Introductory Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2112544-2
    ISSN 1744-8328 ; 1473-7140
    ISSN (online) 1744-8328
    ISSN 1473-7140
    DOI 10.1080/14737140.2020.1753508
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Editorial: Customizing sarcoma management and treatment.

    Blay, Jean-Yves

    Current opinion in oncology

    2019  Volume 31, Issue 4, Page(s) 302–303

    MeSH term(s) Humans ; Sarcoma/diagnosis ; Sarcoma/pathology ; Sarcoma/therapy
    Language English
    Publishing date 2019-05-02
    Publishing country United States
    Document type Editorial ; Introductory Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1049384-0
    ISSN 1531-703X ; 1040-8746
    ISSN (online) 1531-703X
    ISSN 1040-8746
    DOI 10.1097/CCO.0000000000000551
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Treatment of advanced soft tissue sarcoma by histological subtype: wish, prediction or reality?

    Blay, Jean-Yves

    Future oncology (London, England)

    2019  Volume 15, Issue 26s, Page(s) 5–10

    Abstract: Soft tissue sarcomas (STS) are heterogenous cancers encompassing more than 100 histological and molecular subtypes. Their extreme rarity underscores the need for international collaboration to identify specific treatment protocols. Increasing knowledge ... ...

    Abstract Soft tissue sarcomas (STS) are heterogenous cancers encompassing more than 100 histological and molecular subtypes. Their extreme rarity underscores the need for international collaboration to identify specific treatment protocols. Increasing knowledge of STS complexity as defined by molecular biology has led to the introduction of targeted therapies for several sarcoma subtypes, which is an encouraging start. In advanced STS, doxorubicin-based regimens are standard first-line chemotherapy. Options for second and later lines include ifosfamide, trabectedin, pazopanib, eribulin and gemcitabine-based regimens. Histological subtype has become a key factor when selecting best options to treat advanced sarcoma; however, the challenges of identifying optimal treatments for all STS histotypes are undeniably formidable. Fortunately, the sarcoma community shares the common goal of seeking greater knowledge about the characteristics of each subtype in order to improve diagnosis and outcomes. Progress made to date in this regard suggests that the vision to treat by subtype is achievable.
    MeSH term(s) Adult ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Clinical Trials as Topic ; Deoxycytidine/administration & dosage ; Deoxycytidine/analogs & derivatives ; Doxorubicin/administration & dosage ; Female ; Furans/administration & dosage ; Humans ; Ifosfamide/administration & dosage ; Ketones/administration & dosage ; Liposarcoma/drug therapy ; Liposarcoma/pathology ; Middle Aged ; Prognosis ; Pyrimidines/administration & dosage ; Sulfonamides/administration & dosage ; Survival Rate ; Trabectedin/administration & dosage
    Chemical Substances Furans ; Ketones ; Pyrimidines ; Sulfonamides ; Deoxycytidine (0W860991D6) ; pazopanib (7RN5DR86CK) ; Doxorubicin (80168379AG) ; gemcitabine (B76N6SBZ8R) ; Trabectedin (ID0YZQ2TCP) ; eribulin (LR24G6354G) ; Ifosfamide (UM20QQM95Y)
    Language English
    Publishing date 2019-09-10
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2274956-1
    ISSN 1744-8301 ; 1479-6694
    ISSN (online) 1744-8301
    ISSN 1479-6694
    DOI 10.2217/fon-2019-0488
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Management of sarcoma patients: centralization in reference centers to fragmentation of systemic treatment.

    Blay, Jean-Yves

    Current opinion in oncology

    2018  Volume 30, Issue 4, Page(s) 240–242

    MeSH term(s) Adult ; Child ; Humans ; Referral and Consultation ; Sarcoma/genetics ; Sarcoma/metabolism ; Sarcoma/pathology ; Sarcoma/therapy
    Language English
    Publishing date 2018-05-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1049384-0
    ISSN 1531-703X ; 1040-8746
    ISSN (online) 1531-703X
    ISSN 1040-8746
    DOI 10.1097/CCO.0000000000000461
    Database MEDical Literature Analysis and Retrieval System OnLINE

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