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  1. Book ; Thesis: Psychobiologische und neurophysiologische Langzeiteffekte einer multimodalen verhaltensmedizinischen Behandlung bei Kindern und Jugendlichen mit Aufmerksamkeitsdefizit-Hyperaktivitätsstörung

    Blume, Cornelia

    2007  

    Author's details vorgelegt von Cornelia Blume
    Subject code 618.92
    Language German
    Size 75 S., graph. Darst., 21 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Kiel, Univ., Diss., 2007
    HBZ-ID HT015299929
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2007 D 1076 order for loan Magazin

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  2. Book ; Thesis: Ökonomische Evaluation berufsbezogener Maßnahmen in der medizinischen Rehabilitation bei Patienten mit Rückenschmerzen

    Blume, Carsten

    eine Kosten-Nutzen-Analyse aus Rentenversicherungsperspektive

    (Schriften aus dem Institut für Rehabilitationswissenschaften der Humboldt-Universität zu Berlin ; 2007,3)

    2007  

    Author's details Carsten Blume
    Series title Schriften aus dem Institut für Rehabilitationswissenschaften der Humboldt-Universität zu Berlin ; 2007,3
    Collection
    Keywords Rückenschmerz ; Rehabilitation ; Kosten-Nutzen-Analyse ; Rentenversicherung
    Subject Gesetzliche Rentenversicherung ; Soziale Rentenversicherung ; Cost-benefit-Analyse ; Cost-benefit analysis ; Nutzen-Kosten-Analyse ; Kostennutzenanalyse ; Nutzenkostenanalyse ; Rehabilitierung ; Dorsopathie ; Rückenleiden ; Rückenschmerzen
    Subject code 617.56403
    Language German
    Size VII, 111 S. : graph. Darst., 21 cm, 182 gr.
    Publisher Shaker
    Publishing place Aachen
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Berlin, Humboldt-Univ., Diplomarbeit
    HBZ-ID HT015726894
    ISBN 978-3-8322-6553-3 ; 3-8322-6553-8
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2008 A 6230 order for loan Magazin

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  3. Book ; Online: GLEAM - General Learning Evolutionary Algorithm and Method : ein Evolutionärer Algorithmus und seine Anwendungen

    Blume, ChristianJakob, Wilfried

    2009  

    Abstract: Nach einer grundlegenden Einführung wird der Evolutionäre Algorithmus GLEAM ausführlich vorgestellt. Das breite Anwendungspotential dieses Optimierungs- und Planungsverfahrens wird durch eine Reihe von Anwendungsbeispielen aus den Bereichen Robotik, ... ...

    Abstract Nach einer grundlegenden Einführung wird der Evolutionäre Algorithmus GLEAM ausführlich vorgestellt. Das breite Anwendungspotential dieses Optimierungs- und Planungsverfahrens wird durch eine Reihe von Anwendungsbeispielen aus den Bereichen Robotik, Scheduling, Bauindustrie und Designoptimierung unterstrichen. Dabei werden auch Weiterentwicklungen behandelt, die Heuristiken und lokale Suche in das evolutionäre Verfahren integrieren, so dass ein hybrider oder memetischer Algorithmus entsteht
    Keywords Technology (General)
    Size 1 electronic resource (X, 196 p. p.)
    Publisher KIT Scientific Publishing
    Publishing place Verlagsort nicht ermittelbar
    Document type Book ; Online
    Note GERMAN ; Open Access
    HBZ-ID HT020196762
    ISBN 9783866444362 ; 3866444362
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Seasonal Variation in the Responsiveness of the Melanopsin System to Evening Light: Why We Should Report Season When Collecting Data in Human Sleep and Circadian Studies.

    Schöllhorn, Isabel / Stefani, Oliver / Blume, Christine / Cajochen, Christian

    Clocks & sleep

    2023  Volume 5, Issue 4, Page(s) 651–666

    Abstract: It is well known that variations in light exposure during the day affect light sensitivity in the evening. More daylight reduces sensitivity, and less daylight increases it. On average days, we spend less time outdoors in winter and receive far less ... ...

    Abstract It is well known that variations in light exposure during the day affect light sensitivity in the evening. More daylight reduces sensitivity, and less daylight increases it. On average days, we spend less time outdoors in winter and receive far less light than in summer. Therefore, it could be relevant when collecting research data on the non-image forming (NIF) effects of light on circadian rhythms and sleep. In fact, studies conducted only in winter may result in more pronounced NIF effects than in summer. Here, we systematically collected information on the extent to which studies on the NIF effects of evening light include information on season and/or light history. We found that more studies were conducted in winter than in summer and that reporting when a study was conducted or measuring individual light history is not currently a standard in sleep and circadian research. In addition, we sought to evaluate seasonal variations in a previously published dataset of 72 participants investigating circadian and sleep effects of evening light exposure in a laboratory protocol where daytime light history was not controlled. In this study, we selectively modulated melanopic irradiance at four different light levels (<90 lx). Here, we aimed to retrospectively evaluate seasonal variations in the responsiveness of the melanopsin system by combining all data sets in an exploratory manner. Our analyses suggest that light sensitivity is indeed reduced in summer compared to winter. Thus, to increase the reproducibility of NIF effects on sleep and circadian measures, we recommend an assessment of the light history and encourage standardization of reporting guidelines on the seasonal distribution of measurements.
    Language English
    Publishing date 2023-11-01
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2624-5175
    ISSN (online) 2624-5175
    DOI 10.3390/clockssleep5040044
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Ulceroglandular Tularemia in Children.

    Vogel, Bianca / Blume, Christian / Brangenberg, Ralf

    Deutsches Arzteblatt international

    2023  Volume 120, Issue 8, Page(s) 132

    MeSH term(s) Humans ; Child ; Tularemia/diagnosis ; Tularemia/drug therapy ; Skin Ulcer
    Language English
    Publishing date 2023-04-20
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2406159-1
    ISSN 1866-0452 ; 1866-0452
    ISSN (online) 1866-0452
    ISSN 1866-0452
    DOI 10.3238/arztebl.m2022.0393
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Thesis: Die Suspensionsplastik nach Cowan

    Blume, Claudia

    eine Langzeitstudie

    1999  

    Author's details vorgelegt von Claudia Blume
    Language German
    Size 75 S. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Düsseldorf, Univ., Diss., 1999
    HBZ-ID HT010620031
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    99 D 2649 order for loan Magazin

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  7. Book ; Thesis: Effektivität der Pulsatilen Perfusion

    Blume, Christina

    ein Vergleich der Rollerpumpe Stöckert SIII und der Diagonalpumpe DeltaStream® DP 1 durch Bestimmung des Energy Equivalent Pressure im Modellkreislauf

    2010  

    Author's details vorgelegt von Christina Barbara Anna Blume
    Language German
    Size 69, XI Bl. : Ill., graph. Darst., 30 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Hannover, Med. Hochsch., Diss., 2010
    HBZ-ID HT016715548
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2011 E 895 order for loan Magazin

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  8. Article: 'SleepCycles' package for R - A free software tool for the detection of sleep cycles from sleep staging.

    Blume, Christine / Cajochen, Christian

    MethodsX

    2021  Volume 8, Page(s) 101318

    Abstract: The detection of NREM-REM sleep cycles in human sleep data (i.e., polysomnographically assessed sleep stages) enables fine-grained analyses of ultradian variations in sleep microstructure (e.g., sleep spindles, and arousals), or other amplitude- and ... ...

    Abstract The detection of NREM-REM sleep cycles in human sleep data (i.e., polysomnographically assessed sleep stages) enables fine-grained analyses of ultradian variations in sleep microstructure (e.g., sleep spindles, and arousals), or other amplitude- and frequency-specific electroencephalographic features during sleep. While many laboratories have software that is used internally, reproducibility requires the availability of open-source software. Therefore, we here introduce the 'SleepCycles' package for R, an open-source software package that identifies sleep cycles and their respective (non-) rapid eye movement ([N]REM) periods from sleep staging data. Additionally, each (N)REM period is subdivided into parts of equal duration (percentiles), which may be useful for further fine-grained analyses. The detection criteria used in the package are, with some adaptations, largely based on criteria originally proposed by Feinberg and Floyd (1979). The latest version of the package can be downloaded from the Comprehensive R Archives Network (CRAN).•The package 'SleepCycles' for R allows to identify sleep cycles and their respective NREM and REM periods from sleep staging results.•Besides the cycle detection, NREM and REM periods are also split into parts of equal duration (percentiles) thereby allowing for a better temporal resolution across the night and comparisons of sleep cycles with different durations amongst different night recordings.
    Language English
    Publishing date 2021-03-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2830212-6
    ISSN 2215-0161
    ISSN 2215-0161
    DOI 10.1016/j.mex.2021.101318
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: An Intelligent and Efficient Workflow for Path-Oriented 3D Bioprinting of Tubular Scaffolds.

    Baroth, Timo / Loewner, Sebastian / Heymann, Henrik / Cholewa, Fabian / Blume, Holger / Blume, Cornelia

    3D printing and additive manufacturing

    2024  Volume 11, Issue 1, Page(s) 323–332

    Abstract: Modern 3D printing is a valuable tool for tissue engineering (TE), and the fabrication of complex geometries such as tubular scaffolds with adaptable structure, for example, as replacements for intestines, bronchi, esophagus, or vessels, could contribute ...

    Abstract Modern 3D printing is a valuable tool for tissue engineering (TE), and the fabrication of complex geometries such as tubular scaffolds with adaptable structure, for example, as replacements for intestines, bronchi, esophagus, or vessels, could contribute to standardized procedures in the future of regenerative medicine. However, high-precision bioprinting of scaffolds for tubular TE applications remain a major challenge and is an arduous endeavor with currently available three-axis bioprinters, which are limited to planar, layer-by-layer printing processes. In this work, a novel, straightforward workflow for creating toolpaths and command sets for tubular scaffolds is presented. By combining a custom software application with commercial 3D design software, a comparatively large degree of design freedom was achieved while ensuring ease of use and extensibility for future research needs. As a hardware platform, two commercial 3D bioprinters were retrofitted with a rotary axis to accommodate cylindrical mandrels as print beds, overcoming the limitations of planar print beds. The printing process using the new method was evaluated in terms of the mechanical, actuation, and synchronization characteristics of the linear and rotating axes, as well as the stability of the printing process. In this context, it became clear that extrusion-based printing processes are very sensitive to positioning errors when used with small nozzles. Despite these technical difficulties, the new process can produce single-layer, multilayer, and multimaterial structures with a wide range of pore geometries. In addition, extrusion-based printing processes can be combined with melt electrowriting to produce durable scaffolds with features in the micrometer to millimeter range. Overall, the suitability of this setup for a wide range of TE applications has thus been demonstrated.
    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Journal Article
    ISSN 2329-7670
    ISSN (online) 2329-7670
    DOI 10.1089/3dp.2022.0201
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Das Apfelbuch

    Blume, Cornelia / Steinmetz, Burkhard

    Apfelschätze erhalten und genießen

    2005  

    Author's details Cornelia Blume & Burkhard Steinmetz
    Keywords Apfel
    Subject Malus domestica ; Gartenapfel ; Malus communis ; Äpfel
    Language German
    Size 172 S. : Ill.
    Publisher pala-Verl
    Publishing place Darmstdt
    Publishing country Germany
    Document type Book
    HBZ-ID HT014468622
    ISBN 3-89566-219-4 ; 978-3-89566-219-5
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    058/1598 available for loan (reading room) Freihandmagazin (U1)

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    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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