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  1. AU="Bo, L J"
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  1. Article: [Expression and influencing factors of hepcidin in classical paroxysmal nocturnal hemoglobinuria].

    Wang, Y S / Yao, H J / Bo, L J / Zhao, Y P / Zhang, Y L / Zhang, F K

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

    2019  Volume 40, Issue 10, Page(s) 818–821

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Enzyme-Linked Immunosorbent Assay ; Ferritins ; Hemoglobinuria, Paroxysmal ; Hepcidins ; Humans ; Retrospective Studies
    Chemical Substances Hepcidins ; Ferritins (9007-73-2)
    Language Chinese
    Publishing date 2019-11-24
    Publishing country China
    Document type Journal Article
    ISSN 0253-2727
    ISSN 0253-2727
    DOI 10.3760/cma.j.issn.0253-2727.2019.10.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Bioinformatics analysis of miRNA expression profile between primary and recurrent glioblastoma.

    Bo, L-J / Wei, B / Li, Z-H / Wang, Z-F / Gao, Z / Miao, Z

    European review for medical and pharmacological sciences

    2015  Volume 19, Issue 19, Page(s) 3579–3586

    Abstract: Objective: Glioblastoma (GBM) is the most malignant brain tumor with rapid relapse. The goal of this study is to identify microRNAs (miRNAs) involved in recurrent GBM.: Materials and methods: miRNA transcription profile data (GSE32466) were ... ...

    Abstract Objective: Glioblastoma (GBM) is the most malignant brain tumor with rapid relapse. The goal of this study is to identify microRNAs (miRNAs) involved in recurrent GBM.
    Materials and methods: miRNA transcription profile data (GSE32466) were downloaded, including 12 primary GBM samples and 12 recurrent GBM samples. Then, limma package was utilized to identify differentially expressed miRNAs (DEMs) with the criteria of false discovery rate < 0.05 and |log2 fold change| ≥ 1. Thereafter, miTarget and TargetScan databases were used to predict the potential target genes of DEMs. Regulatory co-expression network was constructed based on co-expressed genes and potential miRNA-gene pairs, and then, pathway analysis was conducted. Furthermore, database miRWalk was used to screen out known GBM-associated miRNAs from the identified DEMs.
    Results: A total of 71 DEMs were identified between primary and recurrent GBM samples, and 2684 potential target genes were found. Besides, regulatory co-expression network was constructed, including 12 DEMs and 81 potential target genes. These genes significantly enriched in ECM-receptor interaction, ribosome, and focal adhesion pathways, and DEMs like hsa-miR-320a, hsa-miR-139-5p, has-miR-128, hsa-miR-140-5p, and hsa-miR-146b-5p had high degree. Notably, 7 DEMs in network were known GBM-associated miRNAs recorded in database miRWalk.
    Conclusions: DEMs like hsa-miR-320a, hsa-miR-139-5p, has-miR-128, hsa-miR-146b-5p, hsa-let-7c, hsa-miR-128, and hsa-let-7a might participate in recurrent GBM. These results would pave ways for further study of recurrent GBM mechanism, and for the prevention and treatment of recurrent GBM. However, more experimental verifications are required to prove these predictions.
    MeSH term(s) Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; Computational Biology/methods ; Databases, Factual ; Glioblastoma/genetics ; Glioblastoma/pathology ; Humans ; MicroRNAs/metabolism ; Neoplasm Recurrence, Local
    Chemical Substances MicroRNAs
    Language English
    Publishing date 2015-10
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1887: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Survey of seven organophosphorus pesticides in drinking water, feedstuffs and raw milk from dairy farms in the Province Heilongjiang during 2008-2009

    Zhao, X. H. / Bo, L.-J. / Wang, J. Jing / Li, T. J.

    Milchwissenschaft

    2012  Volume 67, Issue 3, Page(s) 293–296

    Language German ; English
    Document type Article
    ZDB-ID 391678-9
    ISSN 0026-3788
    Database Current Contents Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Z 781: Show issues

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