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  1. Article ; Online: Continuous and Intermittent Glucose Monitoring in 2023.

    Dovc, Klemen / Bode, Bruce W / Battelino, Tadej

    Diabetes technology & therapeutics

    2024  Volume 26, Issue S1, Page(s) S14–S31

    MeSH term(s) Humans ; Blood Glucose Self-Monitoring ; Blood Glucose
    Chemical Substances Blood Glucose
    Language English
    Publishing date 2024-03-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1452816-2
    ISSN 1557-8593 ; 1520-9156
    ISSN (online) 1557-8593
    ISSN 1520-9156
    DOI 10.1089/dia.2024.2502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Continuous and Intermittent Glucose Monitoring in 2022.

    Dovc, Klemen / Bode, Bruce W / Battelino, Tadej

    Diabetes technology & therapeutics

    2023  Volume 25, Issue S1, Page(s) S15–S29

    MeSH term(s) Humans ; Blood Glucose ; Blood Glucose Self-Monitoring
    Chemical Substances Blood Glucose
    Language English
    Publishing date 2023-02-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1452816-2
    ISSN 1557-8593 ; 1520-9156
    ISSN (online) 1557-8593
    ISSN 1520-9156
    DOI 10.1089/dia.2023.2502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Enhancing patient success with GLP-1 analogs

    Kruger, Davida F. / Bode, Bruce W. / Spollett, Geralyn R.

    presented live at the American Association of Diabetes Educators' (AADE'S) 2009 annual meeting in Atlanta, Georgia, on August 7, 2009

    (The diabetes educator ; 36, Suppl. 3 ; Cases in practice)

    2010  

    Title variant Cases in practice
    Institution American Association of Diabetes Educators
    Author's details [Davida F. Kruger, Bruce Bode and Geralyn R. Spollett]
    Series title The diabetes educator ; 36, Suppl. 3
    Cases in practice
    Diabetes educator
    Collection Diabetes educator
    Language English
    Size S. 44S - 74S : Ill., graph. Darst.
    Publisher Sage
    Publishing place Thousand Oaks, CA
    Publishing country United States
    Document type Book
    HBZ-ID HT016504998
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Continuous and Intermittent Glucose Monitoring in 2021.

    Dovc, Klemen / Bode, Bruce W / Battelino, Tadej

    Diabetes technology & therapeutics

    2022  Volume 24, Issue S1, Page(s) S209–S219

    MeSH term(s) Blood Glucose ; Blood Glucose Self-Monitoring ; Glycated Hemoglobin A/analysis ; Humans ; Hypoglycemia
    Chemical Substances Blood Glucose ; Glycated Hemoglobin A
    Language English
    Publishing date 2022-05-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1452816-2
    ISSN 1557-8593 ; 1520-9156
    ISSN (online) 1557-8593
    ISSN 1520-9156
    DOI 10.1089/dia.2022.2514
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Continuous and Intermittent Glucose Monitoring in 2020.

    Bode, Bruce W / Battelino, Tadej / Dovc, Klemen

    Diabetes technology & therapeutics

    2021  Volume 23, Issue S2, Page(s) S16–S31

    MeSH term(s) Blood Glucose ; Blood Glucose Self-Monitoring ; Glycated Hemoglobin A/analysis ; Humans ; Hypoglycemia
    Chemical Substances Blood Glucose ; Glycated Hemoglobin A
    Language English
    Publishing date 2021-06-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1452816-2
    ISSN 1557-8593 ; 1520-9156
    ISSN (online) 1557-8593
    ISSN 1520-9156
    DOI 10.1089/dia.2021.2502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Continuous Glucose Monitoring in 2018.

    Bode, Bruce W / Battelino, Tadej

    Diabetes technology & therapeutics

    2019  Volume 21, Issue S1, Page(s) S13–S31

    MeSH term(s) Adult ; Blood Glucose/analysis ; Blood Glucose Self-Monitoring/history ; Blood Glucose Self-Monitoring/methods ; Diabetes Mellitus, Type 1/blood ; Diabetes Mellitus, Type 1/drug therapy ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/drug therapy ; Female ; History, 21st Century ; Humans ; Hypoglycemic Agents/therapeutic use ; Insulin/therapeutic use ; Male
    Chemical Substances Blood Glucose ; Hypoglycemic Agents ; Insulin
    Language English
    Publishing date 2019-02-12
    Publishing country United States
    Document type Historical Article ; Journal Article ; Review
    ZDB-ID 1452816-2
    ISSN 1557-8593 ; 1520-9156
    ISSN (online) 1557-8593
    ISSN 1520-9156
    DOI 10.1089/dia.2019.2502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Assessing Time in Range with Postprandial Glucose-Focused Titration of Ultra Rapid Lispro (URLi) in People with Type 1 Diabetes.

    Bergenstal, Richard M / Bode, Bruce W / Bhargava, Anuj / Wang, Qianqian / Knights, Alastair W / Chang, Annette M

    Diabetes therapy : research, treatment and education of diabetes and related disorders

    2023  Volume 14, Issue 11, Page(s) 1933–1945

    Abstract: Introduction: To assess time in range (TIR) (70-180 mg/dL) with postprandial glucose (PPG)-focused titration of ultra rapid lispro (URLi; Lyumjev®) in combination with insulin degludec in people with type 1 diabetes (T1D).: Methods: This phase 2, ... ...

    Abstract Introduction: To assess time in range (TIR) (70-180 mg/dL) with postprandial glucose (PPG)-focused titration of ultra rapid lispro (URLi; Lyumjev®) in combination with insulin degludec in people with type 1 diabetes (T1D).
    Methods: This phase 2, single-group, open-label, exploratory study was conducted in 31 participants with T1D on multiple daily injection therapy. Participants were treated with insulin degludec and Lispro for an 11-day lead-in and then URLi for a 46-day treatment period consisting of 35-day titration and 11-day endpoint maintenance period. Glucose targets for the titration period were PPG < 140 mg/dL or < 20% increase from premeal, fasting glucose 80-110 mg/dL, and overnight excursion ± 30 mg/dL or less. Participants used the InPen™ bolus calculator and Dexcom G6 continuous glucose monitoring (CGM).
    Results: Primary endpoint mean TIR (70-180 mg/dL) with URLi during the maintenance period was 70.2%. TIR (70-180 mg/dL) and times below/above range were not significantly different with URLi (maintenance) versus lispro (lead-in). HbA1c decreased from 7.1% at screening to 6.8% at endpoint (least squares mean [LSM] change from baseline, - 0.36%; P < 0.001). Fructosamine and 1,5-anhydroglucitol improved (P < 0.001). Mean hourly glucose using CGM was reduced from 8:00 AM to 4:00 PM with URLi. Overall highest PPG excursion across meals was significantly reduced at URLi endpoint compared with lispro lead-in (mean 56.5 vs 72.4 mg/dL; P < 0.001). Insulin-to-carbohydrate ratio (U/X g) was reduced (more insulin given) at breakfast at URLi endpoint vs lead-in (LSM 9.0 vs 9.7 g; P = 0.002) and numerically decreased at other meals. Total daily insulin dose (TDD) was higher at URLi endpoint compared with lispro lead-in (mean 50.2 vs 47.0 U; P = 0.046) with similar prandial/TDD ratio (mean 52.1% vs 51.2%). There were no severe hypoglycemia events during the study.
    Conclusions: URLi in a basal-bolus regimen focusing on PPG targets demonstrated improved overall glycemic control and reduced PPG excursions without increased hypoglycemia in participants with T1D.
    Trial registration: ClinicalTrial.gov, NCT04585776.
    Language English
    Publishing date 2023-09-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2566702-6
    ISSN 1869-6961 ; 1869-6953
    ISSN (online) 1869-6961
    ISSN 1869-6953
    DOI 10.1007/s13300-023-01476-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Increased Time in Range with Ultra Rapid Lispro Treatment in Participants with Type 2 Diabetes: PRONTO-Time in Range.

    Bailey, Timothy S / Bode, Bruce W / Wang, Qianqian / Knights, Alastair W / Chang, Annette M

    Diabetes therapy : research, treatment and education of diabetes and related disorders

    2023  Volume 14, Issue 5, Page(s) 883–897

    Abstract: Introduction: To evaluate time in range metrics and HbA1c in people with type 2 diabetes (T2D) treated with ultra rapid lispro (URLi) using continuous glucose monitoring (CGM) for the first time in this population.: Methods: This was a Phase 3b, 12- ... ...

    Abstract Introduction: To evaluate time in range metrics and HbA1c in people with type 2 diabetes (T2D) treated with ultra rapid lispro (URLi) using continuous glucose monitoring (CGM) for the first time in this population.
    Methods: This was a Phase 3b, 12-week, single-treatment study in adults with T2D on basal-bolus multiple daily injection (MDI) therapy using basal insulin glargine U-100 along with a rapid-acting insulin analog. Following a 4-week baseline period, 176 participants were newly treated with prandial URLi. Participants used unblinded CGM (Freestyle Libre). Primary endpoint was time in range (TIR) (70-180 mg/dl) during the daytime period at Week 12 compared to baseline with gated secondary endpoints of HbA1c change from baseline and 24-h TIR (70-180 mg/dl).
    Results: Improved glycemic control was observed at Week 12 versus baseline including mean daytime TIR (change from baseline [Δ] 3.8%; P = 0.007), HbA1c (Δ - 0.44%; P < 0.001), and 24-h TIR (Δ 3.3%; P = 0.016) with no significant difference in time below range (TBR). After 12 weeks, there was a statistically significant decrease in postprandial glucose incremental area under curve, overall, across all meals, within 1 h (P = 0.005) or 2 h (P < 0.001) after the start of a meal. Basal, bolus, and total insulin dose were intensified with increased bolus/total dose ratio at Week 12 (50.7%) versus baseline (44.5%; P < 0.001). There were no severe hypoglycemia events during the treatment period.
    Conclusions: In people with T2D, URLi in an MDI regimen was efficacious with improved glycemic control including TIR, HbA1c, and postprandial glucose without increased hypoglycemia/TBR. CLINICAL TRIAL REGISTRATION NUMBER: NCT04605991.
    Language English
    Publishing date 2023-04-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2566702-6
    ISSN 1869-6961 ; 1869-6953
    ISSN (online) 1869-6961
    ISSN 1869-6953
    DOI 10.1007/s13300-023-01400-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Continuous Glucose Monitoring in 2017.

    Battelino, Tadej / Bode, Bruce W

    Diabetes technology & therapeutics

    2018  Volume 20, Issue S1, Page(s) S13–S29

    MeSH term(s) Blood Glucose/analysis ; Blood Glucose Self-Monitoring ; Diabetes Mellitus, Type 1/blood ; Diabetes Mellitus, Type 1/drug therapy ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/drug therapy ; Humans ; Hypoglycemic Agents/therapeutic use ; Insulin/therapeutic use ; Insulin Infusion Systems
    Chemical Substances Blood Glucose ; Hypoglycemic Agents ; Insulin
    Language English
    Publishing date 2018-02-22
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1452816-2
    ISSN 1557-8593 ; 1520-9156
    ISSN (online) 1557-8593
    ISSN 1520-9156
    DOI 10.1089/dia.2018.2502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Continuous and Intermittent Glucose Monitoring in 2019.

    Battelino, Tadej / Dovc, Klemen / Bode, Bruce W

    Diabetes technology & therapeutics

    2020  Volume 22, Issue S1, Page(s) S3–S16

    MeSH term(s) Blood Glucose/analysis ; Blood Glucose Self-Monitoring/methods ; Blood Glucose Self-Monitoring/standards ; Consensus ; Diabetes Mellitus, Type 1/blood ; Diabetes Mellitus, Type 2/blood ; Guidelines as Topic ; Humans ; Reference Values ; Time Factors
    Chemical Substances Blood Glucose
    Language English
    Publishing date 2020-02-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1452816-2
    ISSN 1557-8593 ; 1520-9156
    ISSN (online) 1557-8593
    ISSN 1520-9156
    DOI 10.1089/dia.2020.2501
    Database MEDical Literature Analysis and Retrieval System OnLINE

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