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  1. Book: Atlas Schilddrüsensonografie

    Bojunga, Jörg

    2022  

    Institution Deutsche Gesellschaft für Angewandte Endokrinologie
    Deutsche Gesellschaft für Ultraschall in der Medizin
    Author's details Jörg Bojunga
    Keywords Schilddrüsenkrankheit
    Subject Schilddrüse
    Language German
    Size XII, 161 Seiten, llustrationen, Diagramme
    Edition 1. Auflage
    Publisher Elsevier
    Publishing place München
    Publishing country Germany
    Document type Book
    HBZ-ID HT021392668
    ISBN 978-3-437-21887-3 ; 3-437-21887-5 ; 9783437062025 ; 3437062026
    Database Catalogue ZB MED Medicine, Health

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  2. Book: FKDS-Trainer

    Bojunga, Jörg / Klein, Kathrin / Müller-Marbach, Alexis Michael / Schröder, Erich Adrian / Hofer, Matthias

    ein Arbeitsbuch für den Einstieg in die farbkodierte Duplexsonographie und Echokardiographie

    2023  

    Author's details Matthias Hofer (Hrsg) ; mit Beiträgen von: J. Bojunga, M. Hofer, K. Klein, A. Müller-Marbach, E. Schröder
    Keywords Fachhochschul-/Hochschulausbildung ; Ärzte aller Fachdisziplinen, Studierende der Medizin im Praktischen Jahr ; Blutgefäße ; Dopplersonografie ; Echokardiografie ; Farbduplexsonografie ; Gefäßdarstellung ; Kontrastverstärker ; Sonografie ; Ultraschalldiagnostik ; Farb-Doppler-Sonografie ; Ultraschallkardiografie
    Subject Ultraschallkardiographie ; Echokardiografie ; Echokardiographie ; Ultraschallechokardiographie ; Ultraschallechokardiografie ; Farb-Doppler-Sonographie ; Farbkodierte Duplexsonographie ; Farbkodierte Duplexsonografie ; Color duplex sonography
    Subject code 616.07543
    Language German
    Size 164 Seiten, Illustrationen, Diagramme, 29.5 cm x 20.5 cm, 650 g
    Edition 6. Auflage
    Publisher Didamed Verlag GmbH
    Publishing place Düsseldorf
    Publishing country Germany
    Document type Book
    Note Lernkarte als Beilage
    Accompanying material 1 Beilage
    HBZ-ID HT030387560
    ISBN 978-3-938103-43-2 ; 3-938103-43-4
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Thyroid ultrasound and its ancillary techniques.

    Bojunga, Joerg / Trimboli, Pierpaolo

    Reviews in endocrine & metabolic disorders

    2023  Volume 25, Issue 1, Page(s) 161–173

    Abstract: Ultrasound (US) of the thyroid has been used as a diagnostic tool since the late 1960s. US is the most important imaging tool for diagnosing thyroid disease. In the majority of cases a correct diagnosis can already be made in synopsis of the sonographic ... ...

    Abstract Ultrasound (US) of the thyroid has been used as a diagnostic tool since the late 1960s. US is the most important imaging tool for diagnosing thyroid disease. In the majority of cases a correct diagnosis can already be made in synopsis of the sonographic together with clinical findings and basal thyroid hormone parameters. However, the characterization of thyroid nodules by US remains challenging. The introduction of Thyroid Imaging Reporting and Data Systems (TIRADSs) has improved diagnostic accuracy of thyroid cancer significantly. Newer techniques such as elastography, superb microvascular imaging (SMI), contrast enhanced ultrasound (CEUS) and multiparametric ultrasound (MPUS) expand diagnostic options and tools further. In addition, the use of artificial intelligence (AI) is a promising tool to improve and simplify diagnostics of thyroid nodules and there is evidence that AI can exceed the performance of humans. Combining different US techniques with the introduction of new software, the use of AI, FNB as well as molecular markers might pave the way for a completely new area of diagnostic accuracy in thyroid disease. Finally, interventional ultrasound using US-guided thermal ablation (TA) procedures are increasingly proposed as therapy options for benign as well as malignant thyroid diseases.
    MeSH term(s) Humans ; Thyroid Nodule ; Artificial Intelligence ; Diagnosis, Differential ; Thyroid Neoplasms
    Language English
    Publishing date 2023-11-10
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2185718-0
    ISSN 1573-2606 ; 1389-9155
    ISSN (online) 1573-2606
    ISSN 1389-9155
    DOI 10.1007/s11154-023-09841-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Hepatitis C im Dialog

    Bojunga, Jörg / Sarrazin, Christoph

    100 Fragen - 100 Antworten ; 11 Tab

    2010  

    Author's details hrsg. von Christoph Sarrazin ... Unter Mitarb. von Jörg Bojunga
    Keywords Hepatitis C
    Subject Non-A-Non-B-Hepatitis ; Virushepatitis-Non-A-Non-B ; Hepatitis NANB
    Language German
    Size XII, 113 S. : graph. Darst.
    Edition 2., überarb. Aufl.
    Publisher Thieme
    Publishing place Stuttgart u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT016466547
    ISBN 978-3-13-133392-6 ; 3-13-133392-8
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: Ultrasound of Thyroid Nodules.

    Bojunga, Jörg

    Ultraschall in der Medizin (Stuttgart, Germany : 1980)

    2018  Volume 39, Issue 5, Page(s) 488–511

    Abstract: Thyroid nodules are a common finding in the general population. Ultrasonography is the most sensitive imaging tool for diagnosing thyroid nodules. However, sonographic differentiation of hormonally active versus inactive nodules, and in particular benign ...

    Title translation Sonografie von Schilddrüsenknoten.
    Abstract Thyroid nodules are a common finding in the general population. Ultrasonography is the most sensitive imaging tool for diagnosing thyroid nodules. However, sonographic differentiation of hormonally active versus inactive nodules, and in particular benign versus malignant nodules, remains unreliable. In this context, thyroid scintigraphy has its clinical significance predominantly in diagnosing hormonal activity of thyroid nodules. However, most nodules are benign and a significant number of patients undergo surgery for diagnostic rather than for therapeutic reasons. Efforts of the past years aimed to improve sonographic risk stratification, to predict malignancy of thyroid nodules through standardized diagnostic assessment of validated risk factors, in order to select patients who require further diagnostic workup. In the last years, several imaging and reporting systems, giving standardized categories with rates of malignancy, were evaluated as a basis for further clinical management. Recent technological developments, such as elastography, also show promising data and might be implemented into clinical practice. Ultrasound-guided fine needle aspiration is the key element in the diagnosis of sonographically suspicious thyroid nodules and significantly contributes to the diagnosis of malignancy versus benignity.
    MeSH term(s) Biopsy, Fine-Needle ; Diagnosis, Differential ; Elasticity Imaging Techniques ; Humans ; Image-Guided Biopsy ; Thyroid Neoplasms/diagnostic imaging ; Thyroid Nodule ; Ultrasonography
    Language English
    Publishing date 2018-09-03
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 801064-x
    ISSN 1438-8782 ; 1439-0914 ; 1431-4894 ; 0172-4614
    ISSN (online) 1438-8782
    ISSN 1439-0914 ; 1431-4894 ; 0172-4614
    DOI 10.1055/a-0659-2350
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Zufallsbefund Struma nodosa.

    Koehler, Viktoria Florentine / Bojunga, Jörg

    MMW Fortschritte der Medizin

    2022  Volume 164, Issue 20, Page(s) 62–64

    Title translation Incidental finding of thyroid follicular nodular disease.
    MeSH term(s) Humans ; Incidental Findings ; Thyroid Nodule/diagnostic imaging ; Thyroid Neoplasms/diagnosis ; Thyroid Neoplasms/surgery ; Adenocarcinoma, Follicular ; Goiter, Nodular ; Retrospective Studies
    Language German
    Publishing date 2022-11-14
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1478211-x
    ISSN 1613-3560 ; 1438-3276
    ISSN (online) 1613-3560
    ISSN 1438-3276
    DOI 10.1007/s15006-022-2023-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Schilddrüsenerkrankungen in der Schwangerschaft.

    Bojunga, Jörg / Güngöze, Oya / Hofbauer, Ludwig / Müller, Elisa

    Deutsche medizinische Wochenschrift (1946)

    2023  Volume 148, Issue 1-02, Page(s) 17–26

    Abstract: Thyroid disease is the second most endocrinopathy during pregnancy 1. Thyroid dysfunction affects 2-3 % of pregnant women 2. Early diagnosis and initiation of therapy are important due to the potential complications in both mother and fetus. This article ...

    Title translation Thyroid disease during pregnancy.
    Abstract Thyroid disease is the second most endocrinopathy during pregnancy 1. Thyroid dysfunction affects 2-3 % of pregnant women 2. Early diagnosis and initiation of therapy are important due to the potential complications in both mother and fetus. This article provides an overview of current recommendations regarding thyroid diagnostics and constellations during pregnancy that require therapy.
    MeSH term(s) Female ; Humans ; Pregnancy ; Mothers ; Pregnancy Complications/diagnosis ; Pregnancy Complications/therapy ; Thyroid Diseases/diagnosis ; Thyroid Diseases/therapy
    Language German
    Publishing date 2023-01-02
    Publishing country Germany
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/a-1813-0892
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Autoimmunthyreoiditis.

    Koehler, Viktoria Florentine / Bojunga, Jörg

    Deutsche medizinische Wochenschrift (1946)

    2021  Volume 146, Issue 20, Page(s) 1329–1336

    Abstract: Autoimmune thyroiditis (AIT) is not only one of the most prevalent human autoimmune diseases, but also the most frequent cause of primary hypothyroidism. It is characterized by lymphocytic infiltration of the thyroid gland with subsequent gradual ... ...

    Title translation Autoimmune thyroid disease.
    Abstract Autoimmune thyroiditis (AIT) is not only one of the most prevalent human autoimmune diseases, but also the most frequent cause of primary hypothyroidism. It is characterized by lymphocytic infiltration of the thyroid gland with subsequent gradual destruction and fibrous replacement of thyroid tissue. Genetic predisposition, epigenetic modifications and environmental factors are suspected as disease triggers. Signs and symptoms of hypothyroidism include fatigue, bradycardia, constipation and cold intolerance. In subclinical hypothyroidism, symptoms may be absent. The diagnosis of AIT is based on the presence of antibodies against thyroid specific antigens, primarily anti-thyroid peroxidase antibodies and on a sonographically proven reduced echogenicity of the thyroid parenchyma. The diagnosis of concomitant hypothyroidism is primarily based on clinical signs and symptoms as well as measurement of thyroid-stimulating hormone (TSH)-concentration. Subclinical hypothyroidism is characterized by elevated TSH with normal serum free thyroxine (fT
    MeSH term(s) Hashimoto Disease ; Humans ; Hypothyroidism ; Thyrotropin ; Thyroxine ; Triiodothyronine
    Chemical Substances Triiodothyronine (06LU7C9H1V) ; Thyrotropin (9002-71-5) ; Thyroxine (Q51BO43MG4)
    Language German
    Publishing date 2021-10-13
    Publishing country Germany
    Document type Editorial
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/a-1258-5674
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Characteristics, clinical course and outcome of ventilated patients at a non-surgical intensive care unit in Germany: a single-centre, retrospective observational cohort analysis.

    Grünewaldt, Achim / Peiffer, Kai-Henrik / Bojunga, Jörg / Rohde, Gernot G U

    BMJ open

    2023  Volume 13, Issue 7, Page(s) e069834

    Abstract: Objectives: The objective of this study was to evaluate epidemiological characteristics, clinical course and outcome of mechanically ventilated non-surgical intensive care unit (ICU) patients, with the aim of improving the strategic planning of ICU ... ...

    Abstract Objectives: The objective of this study was to evaluate epidemiological characteristics, clinical course and outcome of mechanically ventilated non-surgical intensive care unit (ICU) patients, with the aim of improving the strategic planning of ICU capacities.
    Design: We conducted a retrospective observational cohort analysis. Data from mechanically ventilated intensive care patients were obtained by investigating electronic health records. The association between clinical parameters and ordinal scale data of clinical course was evaluated using Spearman correlation and Mann-Whitney U test. Relations between clinical parameters and in-hospital mortality rates were examined using binary logistic regression analysis.
    Setting: A single-centre study at the non-surgical ICU of the University Hospital of Frankfurt, Germany (tertiary care-level centre).
    Participants: All cases of critically ill adult patients in need of mechanical ventilation during the years 2013-2015 were included. In total, 932 cases were analysed.
    Results: From a total of 932 cases, 260 patients (27.9%) were transferred from peripheral ward, 224 patients (24.1%) were hospitalised via emergency rescue services, 211 patients (22.7%) were admitted via emergency room and 236 patients (25.3%) via various transfers. In 266 cases (28.5%), respiratory failure was the reason for ICU admission. The length of stay was higher in non-geriatric patients, patients with immunosuppression and haemato-oncological disease or those in need of renal replacement therapy. 431 patients died, which corresponds to an all-cause in-hospital mortality rate of 46.2%. 92 of 172 patients with presence of immunosuppression (53.5%), 111 of 186 patients (59.7%) with pre-existing haemato-oncological disease, 27 of 36 patients (75.0%) under extracorporeal membrane oxygenation (ECMO) therapy, and 182 of 246 patients (74.0%) undergoing renal replacement therapy died. In logistic regression analysis, these subgroups and older age were significantly associated with higher mortality rates.
    Conclusions: Respiratory failure was the main reason for ventilatory support at this non-surgical ICU. Immunosuppression, haemato-oncological diseases, the need for ECMO or renal replacement therapy and older age were associated with higher mortality.
    MeSH term(s) Adult ; Humans ; Retrospective Studies ; Respiration, Artificial ; Intensive Care Units ; Respiratory Insufficiency ; Disease Progression ; Hospital Mortality
    Language English
    Publishing date 2023-07-09
    Publishing country England
    Document type Observational Study ; Journal Article
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2022-069834
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Appropriate and mindful measurement of serum calcitonin in patients with thyroid nodules. A white paper.

    Trimboli, Pierpaolo / Valderrabano, Pablo / Pitoia, Fabian / Piccardo, Arnoldo / Bojunga, Jörg

    Endocrine

    2023  Volume 83, Issue 1, Page(s) 60–64

    Abstract: Medullary thyroid carcinoma (MTC) is an infrequent thyroid malignancy that is often diagnosed at advanced stage with consequent poor prognosis. Thus, the earlier the diagnosis of MTC, the better the prognosis. Unfortunately, the preoperative detection of ...

    Abstract Medullary thyroid carcinoma (MTC) is an infrequent thyroid malignancy that is often diagnosed at advanced stage with consequent poor prognosis. Thus, the earlier the diagnosis of MTC, the better the prognosis. Unfortunately, the preoperative detection of MTC remains challenging in clinical practice. In fact, while ultrasound and fine-needle aspiration cytology have suboptimal performance in this context, measuring serum calcitonin (Ctn), fully recognized as the most reliable test to detect MTC, is not universally accepted as routine test in all patients with thyroid nodule(s). The authors of this paper reappraise critically the matter of Ctn measurement in view of the recent advancements in the literature to point out the essential information to be known, and then to prepare an easy-to-use guide for clinicians to appropriately consider the measurement of serum Ctn during clinical practice.
    MeSH term(s) Humans ; Thyroid Nodule/diagnostic imaging ; Calcitonin ; Thyroid Neoplasms/pathology ; Carcinoma, Neuroendocrine/pathology
    Chemical Substances Calcitonin (9007-12-9)
    Language English
    Publishing date 2023-08-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1194484-5
    ISSN 1559-0100 ; 1355-008X ; 0969-711X
    ISSN (online) 1559-0100
    ISSN 1355-008X ; 0969-711X
    DOI 10.1007/s12020-023-03485-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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