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Article ; Online: A case of surgical site infection with severe spondylitis caused by

Urso, Rocco / Del Prete, Sossio / D'Antonio, Gianpiero / Sorace, Letizia / Albore, Marco / Bolino, Giorgio

2024 , Page(s) 258172241227658

Abstract: We describe a rare case of severe primary spondylitis caused ... ...

Abstract	We describe a rare case of severe primary spondylitis caused by
Language	English
Publishing date	2024-04-15
Publishing country	England
Document type	Journal Article
ZDB-ID	390918-9
ISSN	2042-1834 ; 0025-8172
ISSN (online)	2042-1834
ISSN	0025-8172
DOI	10.1177/00258172241227658
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Article ; Online: Medico-legal scene investigation in the case of burned bodies - a systematic review.

D'Antonio, Gianpiero / Serinelli, Serenella / Albore, Marco / Bolino, Giorgio

The Medico-legal journal

2023 Volume 91, Issue 4, Page(s) 226–230

Abstract: A judicial on-site examination is essential for the correct analysis of a forensic case, particularly when there has been a fatal fire, as heat-related changes to bodies make identification by the forensic pathologist and other specialists difficult ... ...

Abstract	A judicial on-site examination is essential for the correct analysis of a forensic case, particularly when there has been a fatal fire, as heat-related changes to bodies make identification by the forensic pathologist and other specialists difficult along with estimating the post-mortem interval and determining the precise cause and manner of death. We systematically reviewed all relevant articles dating from 2003 to 2022 in the PubMed database with a view to updating recommendations on how best to proceed. Our recommendations highlight the importance of a multidisciplinary team approach involving various forensic specialists.
MeSH term(s)	Humans ; Autopsy ; Burns ; Soft Tissue Injuries
Language	English
Publishing date	2023-10-04
Publishing country	England
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	390918-9
ISSN	2042-1834 ; 0025-8172
ISSN (online)	2042-1834
ISSN	0025-8172
DOI	10.1177/00258172231191214
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Article ; Online: Consent for sexual acts and rape offences: A dangerous international difformity.

Cioffi, Andrea / Bolino, Giorgio / Cecannecchia, Camilla

Medicine, science, and the law

2022 Volume 63, Issue 2, Page(s) 174

MeSH term(s)	Humans ; Rape ; Sex Offenses ; Informed Consent
Language	English
Publishing date	2022-11-13
Publishing country	England
Document type	Letter
ZDB-ID	301137-9
ISSN	2042-1818 ; 0025-8024
ISSN (online)	2042-1818
ISSN	0025-8024
DOI	10.1177/00258024221136684
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Article ; Online: Free access to emergency oral contraceptives (EOCs) in the European Union: A regulatory vacuum to be filled.

Cioffi, Andrea / Cecannecchia, Camilla / Cioffi, Fernanda / Rinaldi, Raffaella / Bolino, Giorgio

The International journal of risk & safety in medicine

2022 Volume 34, Issue 1, Page(s) 75–80

Abstract: Background: According to the World Health Organization (WHO), any woman in childbearing age who have decided not to take permanently an oral contraceptive but who are sexually active has the right to access emergency contraception (EC). Despite this, in ...

Abstract	Background: According to the World Health Organization (WHO), any woman in childbearing age who have decided not to take permanently an oral contraceptive but who are sexually active has the right to access emergency contraception (EC). Despite this, in many European countries there are no specific laws governing the criteria for access to emergency oral contraceptives (EOCs) for girls under 18, especially about the need for third party consent. This normative vacuum is dangerous as it risks creating confusion and entrusting the management of the fundamental right of self-determination to the discretion of others. Moreover, in European Union (EU) countries, there is an inequality in terms of access to contraceptive supplies, reimbursement criteria and the availability of information online. Objective: Our article compares the criteria for access to EOCs (Ulipristal Acetate-UPA and Levonorgestrel-LNG) in the various EU countries to highlight possible disparities and consequent inequalities. Methods: Government and ministerial websites, European agencies websites, and Contraceptive Use by Method 2019 (WHO) have been consulted. Results: There are some differences between the various European countries that could configure inequality in EU countries. Conclusions: It would be appropriate a definitive levelling of the legislation of the European Union on emergency contraception associated with massive information and awareness campaigns.
MeSH term(s)	Female ; Humans ; Contraceptives, Postcoital ; Contraceptives, Oral ; European Union ; Vacuum ; Contraception, Postcoital/methods
Chemical Substances	Contraceptives, Postcoital ; Contraceptives, Oral
Language	English
Publishing date	2022-07-03
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1055458-0
ISSN	1878-6847 ; 0924-6479
ISSN (online)	1878-6847
ISSN	0924-6479
DOI	10.3233/JRS-220011
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Article: The Practice of Teaching and Scientific Research on Cadaveric Material Remains Crucial for Medical Education.

Bolino, Giorgio / Fineschi, Vittorio / Cecannecchia, Camilla / D'Antonio, Gianpiero / Frati, Paola

Clinics and practice

2023 Volume 13, Issue 5, Page(s) 1073–1081

Abstract: The practice of teaching and scientific research on cadaveric material remains crucial for medical education, especially in surgical disciplines. However, in Italy, this practice has been neglected due to legislative insufficiency and financial ... ...

Abstract	The practice of teaching and scientific research on cadaveric material remains crucial for medical education, especially in surgical disciplines. However, in Italy, this practice has been neglected due to legislative insufficiency and financial constraints. Although innovative methods and tools like simulators and e-learning have been adopted, direct hands-on experience with human cadavers remains irreplaceable for medical and surgical education. The absence of clear legislation governing cadaveric dissection has limited availability for teaching and research, resulting in economic burdens for universities and individuals seeking proper surgical training. To address this issue, Law No. 10/2020 and the recent implementing decree were introduced in Italy, providing detailed legislation on the donation of bodies for educational and research purposes. The law emphasizes the importance of respecting the donor's specific choices and aligns with constitutional principles promoting culture, research, and health protection. However, some critical issues related to consent procedures, duration of body availability, and preservation of anatomical parts remain. Additionally, the law's dissemination among the population needs improvement. Future optimization could include allowing donors to choose the timing of body donation and considering different timeframes for body availability. Furthermore, the implementation of consent procedures could be simplified to increase donations. The law should also address the need for appropriate reception centers and allocate resources for effective dissemination. Despite these challenges, Law No. 10/2020 represents a significant step forward in enhancing medical-surgical training, scientific research, and the overall quality of patient care in Italy.
Language	English
Publishing date	2023-09-01
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2605724-4
ISSN	2039-7283 ; 2039-7275
ISSN (online)	2039-7283
ISSN	2039-7275
DOI	10.3390/clinpract13050095
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Article ; Online: Abortion in Europe: Recent legislative changes and risk of inequality.

Cioffi, Andrea / Cecannecchia, Camilla / Cioffi, Fernanda / Bolino, Giorgio / Rinaldi, Raffaella

The International journal of risk & safety in medicine

2021 Volume 33, Issue 3, Page(s) 281–286

Abstract: Background: Induced abortion is a medical practice that has always been much discussed all over the world. Abortion is allowed in most European countries at the request of the woman with limitations that are imposed mainly by the gestational age. ... ...

Abstract	Background: Induced abortion is a medical practice that has always been much discussed all over the world. Abortion is allowed in most European countries at the request of the woman with limitations that are imposed mainly by the gestational age. However, there are legislative differences between European countries which impose stringent limits on the use of induced abortion. Objective: This article analyzes the European legislation on abortion, with a particular focus on countries in which there have been recent legislative changes in recent years, and the possible consequent risk of inequality among European women. Methods: Government and ministerial websites of the countries analyzed have been consulted to investigate abortion laws in Europe. In addition, the Global Abortion Policies Database of the World Health Organization was also consulted for a regulatory comparison. Results: The differences between the various European countries are considerable. Although guaranteed by most legislation, abortion remains a fragile right in some European countries. Conclusion: Different legislation in the various countries of Europe causes difficulties for women who want to have an abortion but who reside in states where there are strict limits to abortion. In addressing the issue of induced abortion, we must not forget that the center of this practice is the woman. For this reason, it is essential to apply a reasoning based on respect for women's rights: freedom, health, and self-determination.
MeSH term(s)	Abortion, Induced ; Europe ; Female ; Humans ; Personal Autonomy ; Pregnancy ; Women's Rights
Language	English
Publishing date	2021-12-13
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1055458-0
ISSN	1878-6847 ; 0924-6479
ISSN (online)	1878-6847
ISSN	0924-6479
DOI	10.3233/JRS-200095
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Article: The "Criminal Shield": Criminal Liability for Healthcare Professionals during the COVID-19 Pandemic.

Bolino, Giorgio / D'Antonio, Gianpiero / Sorace, Letizia / Fazio, Nicola Di / Volonnino, Gianpietro / Russa, Raffaele La / Arcangeli, Mauro / Frati, Paola

Healthcare (Basel, Switzerland)

2023 Volume 11, Issue 19

Abstract: The Sars-CoV-2 pandemic has had important economic, health, political, and jurisprudential implications all over the world. According to innovations already introduced by Law 24/2017, with Decree Law no. 44 of 1 April 2021 and the subsequent conversion ... ...

Abstract	The Sars-CoV-2 pandemic has had important economic, health, political, and jurisprudential implications all over the world. According to innovations already introduced by Law 24/2017, with Decree Law no. 44 of 1 April 2021 and the subsequent conversion law no. 71 of 2021, Italy is the only country in which ad hoc rules have been introduced to limit the professional liability of healthcare professionals during the health emergency. The "criminal shield" can be defined as the Legislator response to the extreme pressure on healthcare professionals during the pandemic.
Language	English
Publishing date	2023-10-01
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2721009-1
ISSN	2227-9032
ISSN	2227-9032
DOI	10.3390/healthcare11192661
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Article ; Online: Dedicated care pathways in Italian hospital emergency rooms for women who are victims of violence and abuse:

De Matteis, Alessandra / Maiese, Aniello / Chinotti, Franceska / Bolino, Giorgio

The Medico-legal journal

2020 Volume 88, Issue 1_suppl, Page(s) 38–42

Abstract: Gender-based violence affects one third of women globally with death the ultimate consequence after repeated violence. Government intervention is imperative. This article focuses on recent Italian legislation that provides a framework to assist victims ... ...

Abstract	Gender-based violence affects one third of women globally with death the ultimate consequence after repeated violence. Government intervention is imperative. This article focuses on recent Italian legislation that provides a framework to assist victims of violence in Italian Emergency Rooms.
MeSH term(s)	Emergency Service, Hospital/standards ; Female ; Forensic Medicine/legislation & jurisprudence ; Gender-Based Violence/prevention & control ; Humans ; Italy ; Practice Guidelines as Topic/standards
Language	English
Publishing date	2020-07-27
Publishing country	England
Document type	Journal Article
ZDB-ID	390918-9
ISSN	2042-1834 ; 0025-8172
ISSN (online)	2042-1834
ISSN	0025-8172
DOI	10.1177/0025817220935906
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Article ; Online: Death Due to Anaphylactic Reaction

Fabio Del Duca / Alice Chiara Manetti / Aniello Maiese / Gabriele Napoletano / Alessandro Ghamlouch / Natascha Pascale / Bolino Giorgio / Frati Paola / Raffaele La Russa

Medicina, Vol 59, Iss 12, p

The Role of the Forensic Pathologist in an Accurate Postmortem Diagnosis

2023 Volume 2184

Abstract: Background and Objectives : The diagnosis of anaphylaxis comprehensively depends on both situational information and laboratory investigations. For this purpose, serum tryptase concentration is examined as an indicator of systemic mast cell mediator ... ...

Abstract	Background and Objectives : The diagnosis of anaphylaxis comprehensively depends on both situational information and laboratory investigations. For this purpose, serum tryptase concentration is examined as an indicator of systemic mast cell mediator release, linked to an underlying anaphylactic process. Increased levels of tryptase may occur in some events different from anaphylaxis, but usually information from crime scene investigations is lacking and autoptic findings are not specific. For legal reasons, it is required to achieve a definite diagnosis of mast cell degranulation that can lead to a certain diagnosis of death from anaphylaxis. Immunohistochemistry seems to be a relatively simple, reliable, and easily repeatable method that can assist the forensic pathologist in the differential diagnosis of death from anaphylaxis. Materials and Methods : This work provides an overview of the current literature on immunohistochemical methods useful in the determination process of anaphylactic-related deaths. A systematic search, according to the PRISMA statement, was performed in databases to identify studies investigating immunohistochemical targets related to anaphylaxis death. Results : This work underscores the importance of anaphylaxis mediators such as tryptase, CD117, and chymase in the immunohistochemical analysis of anaphylactic deaths. Conclusions : According to the reviewed literature, the diagnosis of death due to anaphylaxis should depend not just on the suspicion of an anaphylactic reaction but also on confirming mast cell degranulation through the identification of IHC positivity for inflammatory mediators, particularly in the respiratory tract.
Keywords	anaphylaxis ; anaphylactic-related death ; legal medicine ; forensic science ; differential diagnosis ; autopsy ; Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Scopolamine fatal outcome in an inmate after buscopan® smoking.

Strano-Rossi, Sabina / Mestria, Serena / Bolino, Giorgio / Polacco, Matteo / Grassi, Simone / Oliva, Antonio

International journal of legal medicine

2021 Volume 135, Issue 4, Page(s) 1455–1460

Abstract: Scopolamine is an alkaloid which acts as competitive antagonists to acetylcholine at central and peripheral muscarinic receptors. We report the case of a 41-year-old male convict with a 27-year history of cannabis abuse who suddenly died in the bed of ... ...

Abstract	Scopolamine is an alkaloid which acts as competitive antagonists to acetylcholine at central and peripheral muscarinic receptors. We report the case of a 41-year-old male convict with a 27-year history of cannabis abuse who suddenly died in the bed of his cell after having smoked buscopan® tablets. Since both abuse of substances and recent physical assaults had been reported, we opted for a comprehensive approach (post-mortem computed tomography CT (PMCT), full forensic autopsy, and toxicology testing) to determine which was the cause of the death. Virtopsy found significant cerebral edema and lungs edema that were confirmed at the autopsy and at the histopathological examination. Scopolamine was detected in peripheral blood at the toxic concentration of 14 ng/mL in blood and at 263 ng/mL in urine, and scopolamine butyl bromide at 17 ng/mL in blood and 90 ng/mL in urine. Quetiapine, mirtazapine, lorazepam, diazepam, and metabolites and valproate were also detected (at therapeutic concentrations). Inmates, especially when they have a history of drug abuse, are at risk to use any substance they can find for recreational purposes. In prisons, active surveillance on the management and assumption of prescribed drugs could avoid fatal acute intoxication.
MeSH term(s)	Adult ; Autopsy ; Butylscopolammonium Bromide/poisoning ; Edema/pathology ; Fatal Outcome ; Forensic Toxicology ; Humans ; Male ; Prisoners ; Scopolamine/poisoning ; Substance Abuse Detection
Chemical Substances	Butylscopolammonium Bromide (2Z3E1OF81V) ; Scopolamine (DL48G20X8X)
Language	English
Publishing date	2021-04-23
Publishing country	Germany
Document type	Case Reports
ZDB-ID	1055109-8
ISSN	1437-1596 ; 0937-9827
ISSN (online)	1437-1596
ISSN	0937-9827
DOI	10.1007/s00414-021-02583-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

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