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  1. Article: Enriched Aptamer Libraries in Fluorescence-Based Assays for

    Zhang, Yiting / Xing, Hu / Bolotnikov, Grigory / Krämer, Markus / Gotzmann, Nina / Knippschild, Uwe / Kissmann, Ann-Kathrin / Rosenau, Frank

    Microorganisms

    2023  Volume 11, Issue 9

    Abstract: Rikenella ... ...

    Abstract Rikenella microfusus
    Language English
    Publishing date 2023-09-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11092266
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: IMPATIENT-qPCR: monitoring SELEX success during in vitro aptamer evolution.

    Kissmann, Ann-Kathrin / Bolotnikov, Grigory / Li, Runliu / Müller, Franziska / Xing, Hu / Krämer, Markus / Gottschalk, Kay-E / Andersson, Jakob / Weil, Tanja / Rosenau, Frank

    Applied microbiology and biotechnology

    2024  Volume 108, Issue 1, Page(s) 284

    Abstract: SELEX (Systematic Evolution of Ligands by Exponential enrichment) processes aim on the evolution of high-affinity aptamers as binding entities in diagnostics and biosensing. Aptamers can represent game-changers as constituents of diagnostic assays for ... ...

    Abstract SELEX (Systematic Evolution of Ligands by Exponential enrichment) processes aim on the evolution of high-affinity aptamers as binding entities in diagnostics and biosensing. Aptamers can represent game-changers as constituents of diagnostic assays for the management of instantly occurring infectious diseases or other health threats. Without in-process quality control measures SELEX suffers from low overall success rates. We present a quantitative PCR method for fast and easy quantification of aptamers bound to their targets. Simultaneous determination of melting temperatures (T
    MeSH term(s) Biological Assay ; Oligonucleotides ; Quality Control ; Temperature
    Chemical Substances Oligonucleotides
    Language English
    Publishing date 2024-04-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 392453-1
    ISSN 1432-0614 ; 0171-1741 ; 0175-7598
    ISSN (online) 1432-0614
    ISSN 0171-1741 ; 0175-7598
    DOI 10.1007/s00253-024-13085-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2229: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Robust Fluorometric Aptamer Assay for Direct and Rapid Detection of Clinical Isolates of

    Zhang, Yiting / Xing, Hu / Bolotnikov, Grigory / Krämer, Markus / Bozdogan, Anil / Kissmann, Ann-Kathrin / Weil, Tanja / Spellerberg, Barbara / Stenger, Steffen / Rosenau, Frank

    International journal of molecular sciences

    2024  Volume 25, Issue 6

    Abstract: Infections caused by yeasts of the ... ...

    Abstract Infections caused by yeasts of the genus
    MeSH term(s) Humans ; Candida ; Follow-Up Studies ; Candidiasis/diagnosis ; Candidiasis/drug therapy ; Candida glabrata ; Antifungal Agents/therapeutic use
    Chemical Substances Antifungal Agents
    Language English
    Publishing date 2024-03-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25063444
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The Designed Pore-Forming Antimicrobial Peptide C14R Combines Excellent Activity against the Major Opportunistic Human Pathogen

    Mildenberger, Vanessa / Alpízar-Pedraza, Daniel / Martell-Huguet, Ernesto M / Krämer, Markus / Bolotnikov, Grigory / Otero-Gonzalez, Anselmo J / Weil, Tanja / Rodriguez-Alfonso, Armando / Preising, Nico / Ständker, Ludger / Vogel, Verena / Spellerberg, Barbara / Kissmann, Ann-Kathrin / Rosenau, Frank

    Pharmaceuticals (Basel, Switzerland)

    2024  Volume 17, Issue 1

    Abstract: The diminishing portfolio of mankind's available antibiotics urges science to develop novel potent drugs. Here, we present a peptide fitting the typical blueprint of amphipathic and membrane-active antimicrobial peptides, denominated C14R. This 2 kDa ... ...

    Abstract The diminishing portfolio of mankind's available antibiotics urges science to develop novel potent drugs. Here, we present a peptide fitting the typical blueprint of amphipathic and membrane-active antimicrobial peptides, denominated C14R. This 2 kDa peptide consists of 16 amino acid residues, with seven being either hydrophobic, aromatic, or non-polar, and nine being polar or positively charged, strictly separated on opposite sides of the predicted α-helix. The affinity of the peptide C14R to
    Language English
    Publishing date 2024-01-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph17010083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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